WO2003047526A3 - Cell adhesion and extracellular matrix proteins - Google Patents

Cell adhesion and extracellular matrix proteins Download PDF

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Publication number
WO2003047526A3
WO2003047526A3 PCT/US2002/038437 US0238437W WO03047526A3 WO 2003047526 A3 WO2003047526 A3 WO 2003047526A3 US 0238437 W US0238437 W US 0238437W WO 03047526 A3 WO03047526 A3 WO 03047526A3
Authority
WO
WIPO (PCT)
Prior art keywords
extracellular matrix
cell adhesion
matrix proteins
cadecm
polynucleotides
Prior art date
Application number
PCT/US2002/038437
Other languages
French (fr)
Other versions
WO2003047526A2 (en
Inventor
Mariah R Baughn
Shanya D Becha
Umesh Bhatia
Julie J Blake
Mark L Borowsky
John D Burrill
Angelo M Delegeane
Vicki S Elliott
Ameena R Gandhi
Original Assignee
Incyte Genomics Inc
Mariah R Baughn
Shanya D Becha
Umesh Bhatia
Julie J Blake
Mark L Borowsky
John D Burrill
Angelo M Delegeane
Vicki S Elliott
Ameena R Gandhi
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Incyte Genomics Inc, Mariah R Baughn, Shanya D Becha, Umesh Bhatia, Julie J Blake, Mark L Borowsky, John D Burrill, Angelo M Delegeane, Vicki S Elliott, Ameena R Gandhi filed Critical Incyte Genomics Inc
Priority to AU2002351194A priority Critical patent/AU2002351194A1/en
Publication of WO2003047526A2 publication Critical patent/WO2003047526A2/en
Publication of WO2003047526A3 publication Critical patent/WO2003047526A3/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cell Biology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

Various embodiments of the invention provide human cell adhesion and extracellular matrix proteins (CADECM) and polynucleotides which identify and encode CADECM. Embodiments of the invention also provide expression vectors, host cells, antibodies, agonists, and antagonists. Other embodiments provide methods for diagnosing, treating, or preventing disorders associated with aberrant expression of CADECM.
PCT/US2002/038437 2001-11-30 2002-11-26 Cell adhesion and extracellular matrix proteins WO2003047526A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2002351194A AU2002351194A1 (en) 2001-11-30 2002-11-26 Cell adhesion and extracellular matrix proteins

Applications Claiming Priority (14)

Application Number Priority Date Filing Date Title
US33434301P 2001-11-30 2001-11-30
US60/334,343 2001-11-30
US34027801P 2001-12-07 2001-12-07
US60/340,278 2001-12-07
US34506902P 2002-01-04 2002-01-04
US60/345,069 2002-01-04
US35135202P 2002-01-25 2002-01-25
US60/351,352 2002-01-25
US35716802P 2002-02-14 2002-02-14
US60/357,168 2002-02-14
US36912802P 2002-03-29 2002-03-29
US60/369,128 2002-03-29
US37080202P 2002-04-05 2002-04-05
US60/370,802 2002-04-05

Publications (2)

Publication Number Publication Date
WO2003047526A2 WO2003047526A2 (en) 2003-06-12
WO2003047526A3 true WO2003047526A3 (en) 2003-11-13

Family

ID=27569691

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2002/038437 WO2003047526A2 (en) 2001-11-30 2002-11-26 Cell adhesion and extracellular matrix proteins

Country Status (2)

Country Link
AU (1) AU2002351194A1 (en)
WO (1) WO2003047526A2 (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2643737C (en) 2006-03-13 2020-05-05 Mubio Products Bv Cancer vaccine
US7488584B2 (en) * 2006-03-24 2009-02-10 Picobella Methods for diagnosing and treating kidney and colorectal cancer
CN102245773B (en) 2008-11-03 2014-08-27 阿莱斯亚生物疗法股份有限公司 Antibodies that specifically block the biological activity of a tumor antigen
CA2772551A1 (en) * 2009-08-26 2011-03-03 Immunotope, Inc. Cytotoxic t-lymphocyte-inducing immunogens for prevention, treatment, and diagnosis of cancer
BR112013025198A2 (en) 2011-03-31 2018-12-04 Alethia Biotherapeutics Inc. kidney-associated antigen 1 antibodies and antigen-binding fragments thereof
KR102102239B1 (en) 2012-01-09 2020-04-21 에이디씨 테라퓨틱스 에스에이 Method for treating breast cancer
US20160122742A1 (en) * 2013-05-31 2016-05-05 Marcel Mechali Protein involved in dna replication, and modulation of its activity
EP3330284A1 (en) * 2016-12-05 2018-06-06 Neuronax Sa Use of peptide compounds for promoting survival, growth and cell differentiation

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1996024673A1 (en) * 1995-02-10 1996-08-15 Leukosite, Inc. Mucosal vascular addressins and uses thereof
US5962643A (en) * 1991-07-11 1999-10-05 The Regents Of The University Of California Integrin β subunit and uses thereof
US6037324A (en) * 1996-01-04 2000-03-14 Leukosite, Inc. Inhibitors of MAdCAM-1-mediated interactions and methods of use therefor

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5962643A (en) * 1991-07-11 1999-10-05 The Regents Of The University Of California Integrin β subunit and uses thereof
WO1996024673A1 (en) * 1995-02-10 1996-08-15 Leukosite, Inc. Mucosal vascular addressins and uses thereof
US6037324A (en) * 1996-01-04 2000-03-14 Leukosite, Inc. Inhibitors of MAdCAM-1-mediated interactions and methods of use therefor

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
DATABASE GENBANK [online] 13 May 2003 (2003-05-13), WAMBUTT R. ET AL., XP002965566, accession no. NCBI Database accession no. (AL831998) *
LEUNG E. ET AL.: "Cloning of the mucosal addressin MAdCAM-1 from human brain: identification of novel alternatively spliced transcripts", IMMUNOL. CELL BIOL., vol. 74, no. 6, December 1996 (1996-12-01), pages 490 - 496, XP002965564 *
SHEPPARD ET AL.: "Complete amino acid sequence of a novel integrin beta subunit (beta 6) identified in epithelial cells using the polymerase chain reaction", J. BIOL. CHEM., vol. 265, no. 20, 15 July 1990 (1990-07-15), pages 11502 - 11507, XP001089800 *
SHYJAN ET AL.: "Human mucosal addressin cell adhesion molecule-1 (MAdCAM-1) demonstrates structural and functional similarities to the alpha 4 beta 7-integrin binding domains of murine MAdCAM-1, but extreme divergence of mucin-like sequences", J. IMMUNOL., vol. 156, no. 8, 15 April 1996 (1996-04-15), pages 2851 - 2857, XP002965565 *

Also Published As

Publication number Publication date
AU2002351194A8 (en) 2003-06-17
AU2002351194A1 (en) 2003-06-17
WO2003047526A2 (en) 2003-06-12

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