ATE378041T1 - Durch coazervation hergestellte mikrokapseln mit einem wirkstoff in ethylcellulose als hüllpolymer - Google Patents

Durch coazervation hergestellte mikrokapseln mit einem wirkstoff in ethylcellulose als hüllpolymer

Info

Publication number
ATE378041T1
ATE378041T1 AT04741678T AT04741678T ATE378041T1 AT E378041 T1 ATE378041 T1 AT E378041T1 AT 04741678 T AT04741678 T AT 04741678T AT 04741678 T AT04741678 T AT 04741678T AT E378041 T1 ATE378041 T1 AT E378041T1
Authority
AT
Austria
Prior art keywords
active ingredient
coazervation
ethyl cellulose
shell polymer
micro capsules
Prior art date
Application number
AT04741678T
Other languages
German (de)
English (en)
Inventor
Roberto Golzi
Luigi Boltri
Christian Stollberg
Original Assignee
Eurand Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eurand Spa filed Critical Eurand Spa
Application granted granted Critical
Publication of ATE378041T1 publication Critical patent/ATE378041T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J3/00—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
    • A61J3/005—Coating of tablets or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/167—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface
    • A61K9/1676—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface having a drug-free core with discrete complete coating layer containing drug
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J13/00—Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
    • B01J13/02—Making microcapsules or microballoons
    • B01J13/06—Making microcapsules or microballoons by phase separation
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J13/00—Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
    • B01J13/02—Making microcapsules or microballoons
    • B01J13/06—Making microcapsules or microballoons by phase separation
    • B01J13/08—Simple coacervation, i.e. addition of highly hydrophilic material
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J13/00—Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
    • B01J13/02—Making microcapsules or microballoons
    • B01J13/20—After-treatment of capsule walls, e.g. hardening
    • B01J13/206—Hardening; drying
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Dispersion Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Medicinal Preparation (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT04741678T 2003-05-30 2004-05-28 Durch coazervation hergestellte mikrokapseln mit einem wirkstoff in ethylcellulose als hüllpolymer ATE378041T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT001096A ITMI20031096A1 (it) 2003-05-30 2003-05-30 Microcapsule per coacervazione contenenti farmaco incorporato nel polimero di rivestimento

Publications (1)

Publication Number Publication Date
ATE378041T1 true ATE378041T1 (de) 2007-11-15

Family

ID=30131119

Family Applications (1)

Application Number Title Priority Date Filing Date
AT04741678T ATE378041T1 (de) 2003-05-30 2004-05-28 Durch coazervation hergestellte mikrokapseln mit einem wirkstoff in ethylcellulose als hüllpolymer

Country Status (9)

Country Link
US (2) US20070048385A1 (enExample)
EP (1) EP1628640B1 (enExample)
JP (1) JP4968829B2 (enExample)
AT (1) ATE378041T1 (enExample)
DK (1) DK1628640T3 (enExample)
ES (1) ES2297439T3 (enExample)
IT (1) ITMI20031096A1 (enExample)
PL (1) PL1628640T3 (enExample)
WO (1) WO2004105725A2 (enExample)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101351680B1 (ko) * 2007-03-22 2014-01-15 주식회사 엘지생활건강 마이크로 캡슐，그 제조방법 및 마이크로 캡슐을 포함하는기능성 조성물
EP3003031A1 (en) 2013-06-04 2016-04-13 Vyome Biosciences Pvt Ltd Coated particles and compositions comprising same

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4394287A (en) * 1981-04-10 1983-07-19 Eurand America, Inc. Incorporation of finely divided additives at the surface of microcapsule walls
US4634587A (en) * 1982-07-09 1987-01-06 Key Pharmaceuticals, Inc. Sustained release quinidine dosage form
US4704285A (en) * 1985-11-18 1987-11-03 The Dow Chemical Company Sustained release compositions comprising hydroxypropyl cellulose ethers
JPS62135419A (ja) * 1985-12-06 1987-06-18 Ikeda Mohandou:Kk ジクロフエナク塩の粒状組成物及びその製造法
JPH0832625B2 (ja) * 1987-01-29 1996-03-29 武田薬品工業株式会社 有核顆粒およびその製造法
US5026560A (en) * 1987-01-29 1991-06-25 Takeda Chemical Industries, Ltd. Spherical granules having core and their production
US5252337A (en) * 1991-06-25 1993-10-12 Eurand America, Inc. Controlled release calcium channel blocker microcapsules
EP0706794B1 (en) * 1994-10-14 2001-12-12 Japan Energy Corporation Anti-aids pharmaceutical preparations and processes for the production thereof
DE19539361A1 (de) * 1995-10-23 1997-04-24 Basf Ag Verfahren zur Herstellung von mehrschichtigen, festen Arzneiformen zur oralen oder rektalen Verabreichung
TR199802718T2 (xx) * 1996-06-28 1999-03-22 Schering Corporation Bir triazol mantara kar�� bile�i�ini i�eren a��zdan al�nan bile�im.
FR2758461A1 (fr) * 1997-01-17 1998-07-24 Pharma Pass Composition pharmaceutique presentant une biodisponibilite elevee et son procede de preparation
UA65607C2 (uk) * 1998-03-04 2004-04-15 Орто-Макнейл Фармацевтикал, Інк. Фармацевтична композиція (варіанти) та спосіб її приготування
EP1072257A1 (en) * 1998-04-17 2001-01-31 Taisho Pharmaceutical Co., Ltd Multiple-unit sustained release tablets
DE19930795A1 (de) * 1999-07-03 2001-01-11 Encapbiosystems Ag Schiers Verfahren zur Verkapselung von Substanzen sowie Teilchen dafür

Also Published As

Publication number Publication date
JP2007509844A (ja) 2007-04-19
EP1628640B1 (en) 2007-11-14
ITMI20031096A1 (it) 2004-11-30
ES2297439T3 (es) 2008-05-01
DK1628640T3 (da) 2008-03-17
WO2004105725A2 (en) 2004-12-09
EP1628640A2 (en) 2006-03-01
US20070048385A1 (en) 2007-03-01
WO2004105725A3 (en) 2005-05-26
PL1628640T3 (pl) 2008-06-30
US20130156934A1 (en) 2013-06-20
JP4968829B2 (ja) 2012-07-04
ITMI20031096A0 (it) 2003-05-30

Similar Documents

Publication Publication Date Title
RU2218153C2 (ru) Драже, имеющее ядро, покрытое противогрибковым средством и полимером
BR9909434A (pt) Microcápsulas umectáveis tendo núcleos revestidos de polìmero hidrofóbico
AU2006282675B2 (en) Method for production of single- and multi-layer microcapsules
DK1140012T3 (da) Omdannelse af væskefyldte gelatinekapsler til systemer til kontrolleret frigivelsessystemer ved flere coatinger
BRPI0315142B8 (pt) cápsula de lanzoprazol de liberação modificada
JP2004513187A5 (enExample)
RU2015149770A (ru) Композиция, состоящая из множества частиц, покрытых кишечнорастворимой оболочкой и имеющих белковую внутреннюю оболочку
EP0391518A3 (en) Sustained-release pharmaceutical preparation
ATE446087T1 (de) Mikrokügelchen mit nanokapseln, die ein lipophiles arzneimittel enthalten
WO2011027960A3 (ko) 화장품용 색조캡슐 조성물, 이의 제조방법 및 이를 이용한 화장품 제제
ATE526059T1 (de) Wasserenthaltende puderzubereitung, verfahren zu deren herstellung und kosmetische zubereitung diese enthaltend
DE502004009222D1 (de) Von peroxycarbonsäuren
NO20032017L (no) Kjerne-skallpartikler og fremgangsmåte for deres fremstilling
WO2004028504A8 (en) Modified release dosage forms
ATE257688T1 (de) Heftpflaster mit duftstoffhaltigen mikrokapseln und verfahren zu seiner herstellung
WO1999022724A3 (en) Extended release formulation containing venlafaxin
WO2007051198A3 (en) Photo-responsive microencapsulation materials, compositions and methods of use thereof
ATE378041T1 (de) Durch coazervation hergestellte mikrokapseln mit einem wirkstoff in ethylcellulose als hüllpolymer
HRP20070353T3 (en) Extended release coated minitablets of venlafaxine hydrochloride
ATE444731T1 (de) Geschmacksmaskierte beschichtete teilchen, verfahren zur herstellung und in der mundhöhle dispergierbare tabletten enthaltend die beschichteten teilchen
FR2868442B1 (fr) Fer a repasser comportant un reservoir d'additif
WO2003049706A3 (en) Wrinkle cream comprising hydrophillic and hydrophobic particles
KR890004683A (ko) 복합입자 및 그의 제조방법
JP2023008935A5 (enExample)
NO20030371D0 (no) En reaktor som omfatter et pakket lag av båren katalysator eller båren katalysatorforlöper, og en anvendelse av reaktoren

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties