ATE376558T1 - Neues nichtstrukturelles hcv polypeptid - Google Patents
Neues nichtstrukturelles hcv polypeptidInfo
- Publication number
- ATE376558T1 ATE376558T1 AT00989206T AT00989206T ATE376558T1 AT E376558 T1 ATE376558 T1 AT E376558T1 AT 00989206 T AT00989206 T AT 00989206T AT 00989206 T AT00989206 T AT 00989206T AT E376558 T1 ATE376558 T1 AT E376558T1
- Authority
- AT
- Austria
- Prior art keywords
- polypeptides
- new non
- hcv polypeptide
- polynucleotides
- structural hcv
- Prior art date
Links
- 229920001184 polypeptide Polymers 0.000 title abstract 4
- 102000004196 processed proteins & peptides Human genes 0.000 title abstract 4
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 4
- 102000040430 polynucleotide Human genes 0.000 abstract 3
- 108091033319 polynucleotide Proteins 0.000 abstract 3
- 239000002157 polynucleotide Substances 0.000 abstract 3
- 241000711549 Hepacivirus C Species 0.000 abstract 1
- 230000003197 catalytic effect Effects 0.000 abstract 1
- 230000002163 immunogen Effects 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 230000035772 mutation Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
- C07K14/08—RNA viruses
- C07K14/18—Togaviridae; Flaviviridae
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/53—DNA (RNA) vaccination
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/57—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/24011—Flaviviridae
- C12N2770/24211—Hepacivirus, e.g. hepatitis C virus, hepatitis G virus
- C12N2770/24222—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Virology (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Genetics & Genomics (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US16750299P | 1999-11-24 | 1999-11-24 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE376558T1 true ATE376558T1 (de) | 2007-11-15 |
Family
ID=22607625
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT00989206T ATE376558T1 (de) | 1999-11-24 | 2000-11-22 | Neues nichtstrukturelles hcv polypeptid |
Country Status (9)
| Country | Link |
|---|---|
| EP (1) | EP1233982B1 (de) |
| JP (1) | JP2003516732A (de) |
| KR (1) | KR100788812B1 (de) |
| CN (2) | CN1425027A (de) |
| AT (1) | ATE376558T1 (de) |
| AU (1) | AU2574601A (de) |
| CA (1) | CA2390082C (de) |
| DE (1) | DE60036881T2 (de) |
| WO (1) | WO2001038360A2 (de) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7491808B2 (en) | 2000-06-15 | 2009-02-17 | Novartis Vaccines And Diagnostics, Inc. | HCV non-structural protein mutants and uses thereof |
| US7022830B2 (en) | 2000-08-17 | 2006-04-04 | Tripep Ab | Hepatitis C virus codon optimized non-structural NS3/4A fusion gene |
| US6680059B2 (en) | 2000-08-29 | 2004-01-20 | Tripep Ab | Vaccines containing ribavirin and methods of use thereof |
| AU2001292151B2 (en) * | 2000-08-17 | 2006-05-04 | Tripep Ab | Vaccines containing ribavirin and methods of use thereof |
| US6858590B2 (en) | 2000-08-17 | 2005-02-22 | Tripep Ab | Vaccines containing ribavirin and methods of use thereof |
| EP1436397B1 (de) | 2001-10-11 | 2010-05-12 | Merck Sharp & Dohme Corp. | Hepatitis-c-virus-impfstoff |
| DE60236364D1 (en) | 2001-10-11 | 2010-06-24 | Angeletti P Ist Richerche Bio | Hepatitis-c-virus-impfstoff |
| CN1678630A (zh) * | 2002-07-02 | 2005-10-05 | 希龙公司 | 具有修饰的ns3结构域的hcv融合蛋白 |
| AU2003298605B2 (en) | 2002-10-16 | 2007-10-18 | Gen-Probe Incorporated | Compositions and methods for detecting west nile virus |
| US7927840B2 (en) | 2006-09-11 | 2011-04-19 | Gen Probe Incorporated | Method for detecting West Nile Virus nucleic acids in the 3′ non-coding region |
| GB0226722D0 (en) * | 2002-11-15 | 2002-12-24 | Glaxo Group Ltd | Vaccine |
| EP1765386A4 (de) * | 2004-05-17 | 2008-07-30 | Novartis Vaccines & Diagnostic | Verkürzte ns5-domäne von hepatitis-c-virus sowie diese enthaltende fusionsproteine |
| JP4836281B2 (ja) * | 2004-08-27 | 2011-12-14 | ノバルティス ヴァクシンズ アンド ダイアグノスティクス インコーポレイテッド | Hcv非構造タンパク質変異体およびその使用 |
| EP2460533A3 (de) * | 2004-10-18 | 2014-01-08 | Globeimmune, Inc. | Therapeutikum auf Hefebasis gegen chronische Hepatitis-C-Infection |
| AU2006257323B2 (en) | 2005-06-17 | 2011-12-22 | Msd Italia S.R.L. | Hepatitis C virus nucleic acid vaccine |
| EP2061888A2 (de) * | 2006-08-25 | 2009-05-27 | Novartis AG | Hcv-fusionspolypeptide |
| US8071561B2 (en) | 2007-08-16 | 2011-12-06 | Chrontech Pharma Ab | Immunogen platform |
| US8728489B2 (en) | 2008-09-19 | 2014-05-20 | Globeimmune, Inc. | Immunotherapy for chronic hepatitis C virus infection |
| WO2010112733A1 (fr) * | 2009-03-30 | 2010-10-07 | bioMérieux | Support solide de détection du vhc |
| CN102645534B (zh) * | 2012-04-26 | 2015-08-12 | 杭州市萧山区第一人民医院 | 基于量子点编码微球芯片检测丙型肝炎病毒的方法 |
| CA2906417C (en) | 2013-03-14 | 2022-06-21 | Robert Ziemann | Hcv core lipid binding domain monoclonal antibodies |
| CA2906407A1 (en) * | 2013-03-14 | 2014-09-18 | Abbott Laboratories | Hcv ns3 recombinant antigens and mutants thereof for improved antibody detection |
| EP2968526A4 (de) | 2013-03-14 | 2016-11-09 | Abbott Lab | Hcv-antigen-antikörper-kombinationstest sowie verfahren und zusammensetzungen zur verwendung darin |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5683864A (en) * | 1987-11-18 | 1997-11-04 | Chiron Corporation | Combinations of hepatitis C virus (HCV) antigens for use in immunoassays for anti-HCV antibodies |
| RU2130969C1 (ru) * | 1990-04-04 | 1999-05-27 | Чирон Корпорейшн | Композиция для диагностики гепатита c человека (варианты), способ и набор для обнаружения антител к вирусу гепатита c человека |
| CA2099883A1 (en) * | 1991-11-07 | 1993-05-08 | John A. Kink | Epitope mapping of the c33c region of hcv |
| US5709995A (en) * | 1994-03-17 | 1998-01-20 | The Scripps Research Institute | Hepatitis C virus-derived peptides capable of inducing cytotoxic T lymphocyte responses |
| DE4428705A1 (de) * | 1994-08-12 | 1996-02-15 | Boehringer Mannheim Gmbh | Rekombinantes Antigen aus der NS3-Region des Hepatitis C Virus |
| JP4452401B2 (ja) * | 1997-08-11 | 2010-04-21 | ベーリンガー インゲルハイム (カナダ) リミテッド | C型肝炎ウイルス阻害ペプチドアナログ |
| WO1999028482A2 (en) * | 1997-11-28 | 1999-06-10 | Schering Corporation | Single-chain recombinant complexes of hepatitis c virus ns3 protease and ns4a cofactor peptide |
| KR100628411B1 (ko) * | 1998-01-30 | 2006-09-28 | 더 제너럴 하스피탈 코포레이션 | C형 간염 바이러스의 비구조 단백질을 이용한 유전자면역법 |
| AU772386B2 (en) * | 1999-05-04 | 2004-04-29 | Boehringer Ingelheim (Canada) Ltd. | Surrogate cell-based system and method for assaying the activity of hepatitis C virus NS3 protease |
-
2000
- 2000-11-22 AU AU25746/01A patent/AU2574601A/en not_active Abandoned
- 2000-11-22 KR KR1020027006693A patent/KR100788812B1/ko not_active Expired - Fee Related
- 2000-11-22 CA CA2390082A patent/CA2390082C/en not_active Expired - Fee Related
- 2000-11-22 EP EP00989206A patent/EP1233982B1/de not_active Expired - Lifetime
- 2000-11-22 JP JP2001540123A patent/JP2003516732A/ja active Pending
- 2000-11-22 WO PCT/US2000/032326 patent/WO2001038360A2/en not_active Ceased
- 2000-11-22 CN CN00818577A patent/CN1425027A/zh active Pending
- 2000-11-22 CN CN200910170570A patent/CN101684146A/zh active Pending
- 2000-11-22 AT AT00989206T patent/ATE376558T1/de active
- 2000-11-22 DE DE60036881T patent/DE60036881T2/de not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| AU2574601A (en) | 2001-06-04 |
| DE60036881D1 (de) | 2007-12-06 |
| EP1233982A2 (de) | 2002-08-28 |
| CA2390082C (en) | 2010-06-29 |
| WO2001038360A3 (en) | 2002-03-07 |
| CN101684146A (zh) | 2010-03-31 |
| KR20020065537A (ko) | 2002-08-13 |
| WO2001038360A2 (en) | 2001-05-31 |
| JP2003516732A (ja) | 2003-05-20 |
| KR100788812B1 (ko) | 2007-12-27 |
| EP1233982B1 (de) | 2007-10-24 |
| CA2390082A1 (en) | 2001-05-31 |
| DE60036881T2 (de) | 2008-07-10 |
| WO2001038360A9 (en) | 2002-12-12 |
| CN1425027A (zh) | 2003-06-18 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
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