ATE375348T1 - Analoge von n-acetylardeemin, verfahren zur herstellung und verwendung dieser analogen - Google Patents
Analoge von n-acetylardeemin, verfahren zur herstellung und verwendung dieser analogenInfo
- Publication number
- ATE375348T1 ATE375348T1 AT96942827T AT96942827T ATE375348T1 AT E375348 T1 ATE375348 T1 AT E375348T1 AT 96942827 T AT96942827 T AT 96942827T AT 96942827 T AT96942827 T AT 96942827T AT E375348 T1 ATE375348 T1 AT E375348T1
- Authority
- AT
- Austria
- Prior art keywords
- cr3r3
- hydrogen
- linear
- branched chain
- chr4
- Prior art date
Links
- XTLQWSBGQKPGCF-YWDSKPHESA-N 5-n-acetylardeemin Chemical class C1=CC=C2C(=O)N3[C@H](C)C(=O)N4[C@H](N(C(C)=O)C=5C6=CC=CC=5)[C@@]6(C(C)(C)C=C)C[C@H]4C3=NC2=C1 XTLQWSBGQKPGCF-YWDSKPHESA-N 0.000 title 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 8
- 239000001257 hydrogen Substances 0.000 abstract 8
- 150000002431 hydrogen Chemical class 0.000 abstract 6
- 125000000217 alkyl group Chemical group 0.000 abstract 4
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 abstract 3
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 3
- 150000001875 compounds Chemical class 0.000 abstract 2
- 229910052736 halogen Inorganic materials 0.000 abstract 2
- 150000002367 halogens Chemical class 0.000 abstract 2
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 125000002252 acyl group Chemical group 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000003282 alkyl amino group Chemical group 0.000 abstract 1
- 125000004414 alkyl thio group Chemical group 0.000 abstract 1
- 125000003236 benzoyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C(*)=O 0.000 abstract 1
- 125000004663 dialkyl amino group Chemical group 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 230000035945 sensitivity Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/22—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains four or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Hematology (AREA)
- Pharmacology & Pharmacy (AREA)
- Oncology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Saccharide Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US675095P | 1995-11-15 | 1995-11-15 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE375348T1 true ATE375348T1 (de) | 2007-10-15 |
Family
ID=21722393
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT96942827T ATE375348T1 (de) | 1995-11-15 | 1996-11-15 | Analoge von n-acetylardeemin, verfahren zur herstellung und verwendung dieser analogen |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US6147076A (de) |
| EP (1) | EP0815111B1 (de) |
| JP (1) | JPH10512899A (de) |
| AT (1) | ATE375348T1 (de) |
| AU (1) | AU729877B2 (de) |
| CA (1) | CA2209775C (de) |
| DE (1) | DE69637283D1 (de) |
| MX (1) | MX9705309A (de) |
| WO (1) | WO1997018215A1 (de) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1999015174A1 (en) * | 1997-09-22 | 1999-04-01 | Sloan-Kettering Institute For Cancer Research | Reverse prenyl compounds as immunosuppressants |
| EP1343758A1 (de) | 2000-11-08 | 2003-09-17 | K.U. Leuven Research & Development | Als kontrastmittel geeignete, substituierte bisindolderivate, diese enthaltende pharmazeutische zusammensetzungen und zwischenprodukte zu deren herstellung |
| CN102276615B (zh) * | 2011-08-26 | 2013-10-23 | 四川大学 | 一种制备甲酰阿地咪的方法 |
| WO2014089177A2 (en) * | 2012-12-04 | 2014-06-12 | Massachusetts Institute Of Technology | Compounds, conjugates and compositions of epipolythiodiketopiperazines and polythiodiketopiperazines |
| CN103113376B (zh) * | 2013-02-04 | 2015-03-04 | 浙江工业大学 | 一种生物碱及制备方法和应用 |
| WO2017197045A1 (en) | 2016-05-11 | 2017-11-16 | Movassaghi Mohammad | Convergent and enantioselective total synthesis of communesin analogs |
| WO2018209239A1 (en) | 2017-05-11 | 2018-11-15 | Massachusetts Institute Of Technology | Potent agelastatin derivatives as modulators for cancer invasion and metastasis |
| US10640508B2 (en) | 2017-10-13 | 2020-05-05 | Massachusetts Institute Of Technology | Diazene directed modular synthesis of compounds with quaternary carbon centers |
| US11535634B2 (en) | 2019-06-05 | 2022-12-27 | Massachusetts Institute Of Technology | Compounds, conjugates, and compositions of epipolythiodiketopiperazines and polythiodiketopiperazines and uses thereof |
| CN110724149B (zh) * | 2019-10-17 | 2022-04-05 | 中山大学 | 一种海洋真菌来源的吲哚生物碱二聚体化合物及制备方法与抗海洋污损生物防除剂中的应用 |
| WO2022006145A1 (en) * | 2020-06-29 | 2022-01-06 | Zymergen Inc. | Modulus modifiers and films thereof |
| US12030888B2 (en) | 2021-02-24 | 2024-07-09 | Massachusetts Institute Of Technology | Himastatin derivatives, and processes of preparation thereof, and uses thereof |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS58152487A (ja) * | 1982-03-05 | 1983-09-10 | Fujisawa Pharmaceut Co Ltd | Ｆｒ−９００２２０物質およびその製造法 |
| JPS6041678A (ja) * | 1983-08-16 | 1985-03-05 | Fujisawa Pharmaceut Co Ltd | インド−ル誘導体 |
| JPH06505474A (ja) * | 1991-01-31 | 1994-06-23 | アボツト・ラボラトリーズ | エンドセリン転換酵素阻害剤 |
| US5196420A (en) * | 1991-07-19 | 1993-03-23 | The United States Of America As Represented By The Secretary Of Agriculture | Cycloechinulin antiinsectan metabolite |
| US5284947A (en) * | 1992-09-15 | 1994-02-08 | Abbott Laboratories | Multiple drug resistance-attenuating compounds |
| US5338845A (en) * | 1992-12-02 | 1994-08-16 | Sterling Winthrop Inc. | Aspergillus species, cyclic dimeric dipeptide derivative substance P antagonist biosynthetic products thereof, and process for preparation thereof |
-
1996
- 1996-11-15 AU AU11425/97A patent/AU729877B2/en not_active Ceased
- 1996-11-15 JP JP9519179A patent/JPH10512899A/ja not_active Ceased
- 1996-11-15 CA CA002209775A patent/CA2209775C/en not_active Expired - Fee Related
- 1996-11-15 US US08/749,908 patent/US6147076A/en not_active Expired - Fee Related
- 1996-11-15 WO PCT/US1996/019086 patent/WO1997018215A1/en not_active Ceased
- 1996-11-15 AT AT96942827T patent/ATE375348T1/de not_active IP Right Cessation
- 1996-11-15 EP EP96942827A patent/EP0815111B1/de not_active Expired - Lifetime
- 1996-11-15 DE DE69637283T patent/DE69637283D1/de not_active Expired - Lifetime
-
1997
- 1997-07-14 MX MX9705309A patent/MX9705309A/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| MX9705309A (es) | 1998-06-30 |
| DE69637283D1 (de) | 2007-11-22 |
| CA2209775C (en) | 2006-01-24 |
| EP0815111A4 (de) | 1998-05-06 |
| WO1997018215A1 (en) | 1997-05-22 |
| CA2209775A1 (en) | 1997-05-22 |
| US6147076A (en) | 2000-11-14 |
| AU729877B2 (en) | 2001-02-15 |
| AU1142597A (en) | 1997-06-05 |
| EP0815111B1 (de) | 2007-10-10 |
| EP0815111A1 (de) | 1998-01-07 |
| JPH10512899A (ja) | 1998-12-08 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ATE375348T1 (de) | Analoge von n-acetylardeemin, verfahren zur herstellung und verwendung dieser analogen | |
| BG102792A (bg) | Производни на заместени 4-хидроксифенилалканоилови киселини с агонистична активност към рраr-гама | |
| DE69738740D1 (de) | Verwendung von Oestrogen Antagonisten und Oestrogen Agonisten zur Behandlung von pathologischen Zuständen | |
| EA200000834A1 (ru) | Фунгицидные 7-алкилтриазолопиримидины | |
| DE69725007D1 (de) | Delta 1,6 bicyclo (4,4,0) basierte farbstoffe zur kontrastverstaerkung in der optischen bilderzeugung | |
| KR850007975A (ko) | 6-클로로벤즈아졸릴옥시아세트아미드의 제조방법 | |
| DE69521615D1 (de) | Streptogramine in gereinigter form, ihre herstellung und diese enthaltende pharmazeutische zusammensetzungen | |
| ATE112762T1 (de) | Herstellung und verwendung von n-jodopropargyl- oxycarbonylaminosäure-estern als antimicrobielle mittel. | |
| ATE199710T1 (de) | Aromatische diselenide und selenosulfide zur verwendung als antioxidans-mittel | |
| EP0618899A4 (de) | Aromatische ester von phenylendialkanoaten als inhibitoren humaner neutrophiler elastase. | |
| ES2134732B1 (es) | "mezclas estabilizantes". | |
| AU590030B2 (en) | Antihypertensive combination product | |
| EA199901006A1 (ru) | Фунгицидная смесь | |
| BR9307288A (pt) | Composto processo para a preparação do mesmo composição herbicida e processo de combate de crescimento de vegetais indesejáveis num local | |
| EA200200665A1 (ru) | Новые соединения бензолсульфонамида, способ их получения и фармацевтические композиции, их содержащие | |
| EA199901023A1 (ru) | Фунгицидная смесь | |
| SE8504346L (sv) | N-alkyl(en)-n-(o,o-disubstituerad tiofosforyl)-n',n'-disubstituerade glycinamider, sett att framstella dessa samt akaricid, insekticid och fungicid, innehallande dess foreningar som verksam bestandsdel | |
| DK0434095T3 (da) | Phenylacetonitrilalkylaminoalkyl-ortho-substituerede arylforbindelser som immunosuppressorer | |
| YU132789A (sh) | Novi dekapeptidi | |
| CO4761030A1 (es) | Mezclas fungicidas que contienen al menos un compuesto seleccionado de carbamatos con grupos aromaticos y un carbamato alifatico | |
| EA200001157A3 (ru) | Новые замещенные производные (дигидро)бензоксазина и (дигидро)бензотиазина, способ их получения и содержащие их фармацевтические композиции | |
| ES8800663A1 (es) | Procedimiento para preparar compuestos arilsulfonicos. | |
| ATE46340T1 (de) | Oximinophosphorsaeurederivate, verfahren zu ihrer herstellung und ihre verwendung zur bekaempfung von schaedlingen. | |
| ES458283A1 (es) | Procedimiento para preparar pirimidinas difosforiladas. | |
| EA200300656A1 (ru) | Фунгицидная смесь |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |