ATE368861T1 - Neuartige verwendungen von durch ble-gene kodierten proteinen und antibiotika aus der bleomycin-familie - Google Patents

Neuartige verwendungen von durch ble-gene kodierten proteinen und antibiotika aus der bleomycin-familie

Info

Publication number
ATE368861T1
ATE368861T1 AT03811464T AT03811464T ATE368861T1 AT E368861 T1 ATE368861 T1 AT E368861T1 AT 03811464 T AT03811464 T AT 03811464T AT 03811464 T AT03811464 T AT 03811464T AT E368861 T1 ATE368861 T1 AT E368861T1
Authority
AT
Austria
Prior art keywords
protein
ble
bleomycin family
antibiotic
bleomycin
Prior art date
Application number
AT03811464T
Other languages
English (en)
Inventor
Darren Hart
Ben Godber
Jonathan M Blackburn
Mike Mcandrews
Original Assignee
Sense Proteomic Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB0224872A external-priority patent/GB0224872D0/en
Priority claimed from GB0229640A external-priority patent/GB2385327A/en
Priority claimed from GB0307379A external-priority patent/GB2400102A/en
Application filed by Sense Proteomic Ltd filed Critical Sense Proteomic Ltd
Application granted granted Critical
Publication of ATE368861T1 publication Critical patent/ATE368861T1/de

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/94—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving narcotics or drugs or pharmaceuticals, neurotransmitters or associated receptors
    • G01N33/9446—Antibacterials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/68—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
    • A61K47/6801—Drug-antibody or immunoglobulin conjugates defined by the pharmacologically or therapeutically active agent
    • A61K47/6803—Drugs conjugated to an antibody or immunoglobulin, e.g. cisplatin-antibody conjugates
    • A61K47/6807—Drugs conjugated to an antibody or immunoglobulin, e.g. cisplatin-antibody conjugates the drug or compound being a sugar, nucleoside, nucleotide, nucleic acid, e.g. RNA antisense
    • A61K47/6809—Antibiotics, e.g. antitumor antibiotics anthracyclins, adriamycin, doxorubicin or daunomycin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2415/00—Assays, e.g. immunoassays or enzyme assays, involving penicillins or cephalosporins
AT03811464T 2002-10-25 2003-10-27 Neuartige verwendungen von durch ble-gene kodierten proteinen und antibiotika aus der bleomycin-familie ATE368861T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB0224872A GB0224872D0 (en) 2002-10-25 2002-10-25 Probe for mass spectrometry
GB0229640A GB2385327A (en) 2001-12-21 2002-12-20 Probe for mass spectrometry
GB0307379A GB2400102A (en) 2003-03-31 2003-03-31 Uses of Ble proteins and bleomycin

Publications (1)

Publication Number Publication Date
ATE368861T1 true ATE368861T1 (de) 2007-08-15

Family

ID=32329543

Family Applications (1)

Application Number Title Priority Date Filing Date
AT03811464T ATE368861T1 (de) 2002-10-25 2003-10-27 Neuartige verwendungen von durch ble-gene kodierten proteinen und antibiotika aus der bleomycin-familie

Country Status (9)

Country Link
US (1) US20060194715A1 (de)
EP (1) EP1565754B1 (de)
JP (2) JP2006506447A (de)
AT (1) ATE368861T1 (de)
AU (1) AU2003302133A1 (de)
DE (1) DE60315343T2 (de)
DK (1) DK1565754T3 (de)
ES (1) ES2290556T3 (de)
WO (1) WO2004046730A2 (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7094568B2 (en) * 2000-08-17 2006-08-22 Sense Proteomic Ltd. Method for producing proteins tagged at the N- or C-terminus
US20040002078A1 (en) 2001-12-05 2004-01-01 Sense Proteomic Limited Arrays
DK2078197T3 (en) * 2006-11-01 2016-05-23 Ventana Med Syst Inc Haptenes, hapten conjugates, compositions thereof and processes for their preparation and use
CN101199866B (zh) * 2007-12-27 2010-09-22 高景星 一种具有多种生物活性的可溶性棉纤维及其制备方法
GB2460717A (en) 2008-06-11 2009-12-16 Sense Proteomic Ltd Autoantibodies for the detection of a predisposition to Lupus
GB2478734A (en) 2010-03-15 2011-09-21 Sense Proteomic Ltd Auto-antibody biomarkers of prostate cancer
GB201017520D0 (en) 2010-10-15 2010-12-01 Sense Proteomic Ltd Biomarkers
EP3267206B1 (de) 2012-03-30 2020-07-22 BD Kiestra B.V. Automatisierte auswahl von mikroorganismen und identifikation mittels maldi
JP6231263B2 (ja) * 2012-07-17 2017-11-15 株式会社島津製作所 アフィニティ支持体及びそれを用いた物質の捕捉方法
CN104569325B (zh) * 2014-12-26 2016-11-23 华中农业大学 用于检测食品中氨基糖苷类抗生素残留的抗体芯片试剂盒及方法
CN112116950B (zh) * 2020-09-10 2022-08-12 南京理工大学 基于深度度量学习的蛋白质折叠识别方法
WO2023122567A1 (en) * 2021-12-21 2023-06-29 Absci Corporation Fola selection assay to identify strains with increased soluble target protein expression

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS59225064A (ja) * 1983-06-03 1984-12-18 ユニチカ株式会社 生理活性物質固定化用担体
US4705616A (en) * 1986-09-15 1987-11-10 Sepragen Corporation Electrophoresis-mass spectrometry probe
US5420228A (en) * 1991-04-05 1995-05-30 University Of Pittsburgh Of The Commonwealth System Of Higher Education Fluorescent-labelled bleomycin analogues
FR2706678B1 (fr) * 1993-06-10 1995-07-13 Commissariat Energie Atomique Sonde de spectrométrie de masse, notamment en plasma magnétisé.
US6027900A (en) * 1996-04-12 2000-02-22 Carnegie Institution Of Washington Methods and tools for transformation of eukaryotic algae
BR0113330A (pt) * 2000-08-17 2003-12-30 Procognia Ltd Método para produção de uma ou mais proteìnas, biblioteca de proteìnas rotuladas, método para a produção de um arranjo de proteìnas, arranjo, métodos de triagem de um ou mais compostos para atividade biológica, de uma ou mais proteìnas para interações de proteìna-proteìna e de proteìna-ácido nucleico especìfica, uso de um arranjo, métodos de geração de um arranjo de anticorpos, e de triagem de abund ncia de ou função de proteìnas, e, uso de uma proteìna rotulada
US20030022151A1 (en) * 2001-01-17 2003-01-30 Gopal Thinakaran Functional screening

Also Published As

Publication number Publication date
DK1565754T3 (da) 2007-12-17
DE60315343T2 (de) 2008-04-17
JP2006506447A (ja) 2006-02-23
DE60315343D1 (de) 2007-09-13
ES2290556T3 (es) 2008-02-16
AU2003302133A8 (en) 2004-06-15
WO2004046730A2 (en) 2004-06-03
WO2004046730A3 (en) 2004-09-02
JP2010156715A (ja) 2010-07-15
EP1565754B1 (de) 2007-08-01
US20060194715A1 (en) 2006-08-31
EP1565754A2 (de) 2005-08-24
AU2003302133A1 (en) 2004-06-15

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