ATE359504T1 - Vorkonzentrierende verbindungstelle für die kupplung von flüssiger chromatographie und kapillarelektrophorese - Google Patents
Vorkonzentrierende verbindungstelle für die kupplung von flüssiger chromatographie und kapillarelektrophoreseInfo
- Publication number
- ATE359504T1 ATE359504T1 AT04015701T AT04015701T ATE359504T1 AT E359504 T1 ATE359504 T1 AT E359504T1 AT 04015701 T AT04015701 T AT 04015701T AT 04015701 T AT04015701 T AT 04015701T AT E359504 T1 ATE359504 T1 AT E359504T1
- Authority
- AT
- Austria
- Prior art keywords
- separation
- electrodes
- preconcentrating
- joint
- liquid chromatography
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
- G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
- G01N27/416—Systems
- G01N27/447—Systems using electrophoresis
- G01N27/44756—Apparatus specially adapted therefor
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/26—Conditioning of the fluid carrier; Flow patterns
- G01N30/38—Flow patterns
- G01N30/46—Flow patterns using more than one column
- G01N30/461—Flow patterns using more than one column with serial coupling of separation columns
- G01N30/463—Flow patterns using more than one column with serial coupling of separation columns for multidimensional chromatography
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/84—Preparation of the fraction to be distributed
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/88—Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/88—Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86
- G01N2030/8809—Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86 analysis specially adapted for the sample
- G01N2030/8813—Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86 analysis specially adapted for the sample biological materials
- G01N2030/8831—Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86 analysis specially adapted for the sample biological materials involving peptides or proteins
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/26—Conditioning of the fluid carrier; Flow patterns
- G01N30/38—Flow patterns
- G01N30/46—Flow patterns using more than one column
- G01N30/461—Flow patterns using more than one column with serial coupling of separation columns
- G01N30/465—Flow patterns using more than one column with serial coupling of separation columns with specially adapted interfaces between the columns
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Physics & Mathematics (AREA)
- Pathology (AREA)
- Molecular Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Electrochemistry (AREA)
- Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
- Peptides Or Proteins (AREA)
- Solid-Sorbent Or Filter-Aiding Compositions (AREA)
- Pyridine Compounds (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Electrochromic Elements, Electrophoresis, Or Variable Reflection Or Absorption Elements (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP04015701A EP1612550B1 (de) | 2004-07-03 | 2004-07-03 | Vorkonzentrierende Verbindungstelle für die Kupplung von flüssiger Chromatographie und Kapillarelektrophorese |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE359504T1 true ATE359504T1 (de) | 2007-05-15 |
Family
ID=34925611
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT06013800T ATE388397T1 (de) | 2004-07-03 | 2004-07-03 | Vorkonzentrationsverbindung zur kopplung von kapillarer elektrochromatografie und kapillarzonenelektrophorese |
AT04015701T ATE359504T1 (de) | 2004-07-03 | 2004-07-03 | Vorkonzentrierende verbindungstelle für die kupplung von flüssiger chromatographie und kapillarelektrophorese |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT06013800T ATE388397T1 (de) | 2004-07-03 | 2004-07-03 | Vorkonzentrationsverbindung zur kopplung von kapillarer elektrochromatografie und kapillarzonenelektrophorese |
Country Status (7)
Country | Link |
---|---|
US (1) | US7820023B2 (de) |
EP (2) | EP1612550B1 (de) |
JP (1) | JP4527619B2 (de) |
AT (2) | ATE388397T1 (de) |
CA (1) | CA2511079A1 (de) |
DE (2) | DE602004005843T2 (de) |
ES (2) | ES2301118T3 (de) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7641780B2 (en) * | 2001-05-01 | 2010-01-05 | Calibrant Biosystems, Inc. | Two-dimensional microfluidics for protein separations and gene analysis |
US20080156080A1 (en) * | 2007-01-02 | 2008-07-03 | Calibrant Biosystems, Inc. | Methods and systems for multidimensional concentration and separation of biomolecules using capillary isotachophoresis |
US20080160629A1 (en) * | 2007-01-02 | 2008-07-03 | Calibrant Biosystems, Inc. | Methods and systems for off-line multidimensional concentration and separation of biomolecules |
KR20100087130A (ko) * | 2007-09-26 | 2010-08-03 | 메사추세츠 인스티튜트 오브 테크놀로지 | 전기역학적 농축 장치 및 그의 사용 방법 |
JP5047928B2 (ja) * | 2008-11-11 | 2012-10-10 | シャープ株式会社 | 電気泳動装置およびその構成器具 |
CZ303056B6 (cs) | 2010-12-14 | 2012-03-14 | Mikrobiologický ústav AV CR, v.v.i. | Zpusob modifikace povrchu pro prekoncentraci fosforylovaných peptidu pro desorpcne-ionizacní techniky hmotnostní spektrometrie |
US8871072B2 (en) * | 2011-09-28 | 2014-10-28 | The United States Of America, As Represented By The Secretary Of The Navy | Flow step focusing |
CZ307023B6 (cs) * | 2013-05-20 | 2017-11-22 | Ăšstav analytickĂ© chemie AV ÄŚR, v. v. i. | Způsob předkoncentrace složek kapalných vzorků |
CN103638691B (zh) * | 2013-11-01 | 2015-07-22 | 朱江 | 混合物分离纯化用交变弱电场阵列电子色谱分离方法 |
CN110327994B (zh) * | 2019-07-11 | 2020-12-08 | 北京理工大学 | 一种多维微流控电泳芯片及检测装置,检测方法 |
CN112098501B (zh) * | 2020-09-15 | 2023-12-05 | 中国科学院合肥物质科学研究院 | 一种面向高毒性VOCs混合物现场检测的nafion-FAIMS检测装置及方法 |
Family Cites Families (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3735640A (en) * | 1972-03-10 | 1973-05-29 | L Chizhov | Apparatus for injecting a sample into a gas chromatograph |
US4043678A (en) * | 1976-03-01 | 1977-08-23 | Technicon Instruments Corporation | Cuvette |
GB2225339A (en) * | 1988-11-15 | 1990-05-30 | Aligena Ag | Separating electrically charged macromolecular compounds by forced-flow membrane electrophoresis |
US5240577A (en) * | 1990-11-13 | 1993-08-31 | University Of North Carolina At Chapel Hill | Two-dimensional high-performance liquid chromatography/capillary electrophoresis |
EP0488947B1 (de) * | 1990-11-26 | 1995-02-15 | Ciba-Geigy Ag | Detektorzelle |
US6074827A (en) * | 1996-07-30 | 2000-06-13 | Aclara Biosciences, Inc. | Microfluidic method for nucleic acid purification and processing |
US6387234B1 (en) * | 1998-08-31 | 2002-05-14 | Iowa State University Research Foundation, Inc. | Integrated multiplexed capillary electrophoresis system |
WO2001053794A1 (en) | 2000-01-18 | 2001-07-26 | Northeastern University | Parallel sample loading and injection device for multichannel microfluidic devices |
US6749735B1 (en) * | 2000-03-16 | 2004-06-15 | David Le Febre | Electromobility focusing controlled channel electrophoresis system |
US6558523B1 (en) * | 2000-04-10 | 2003-05-06 | The Regents Of The University Of California | Injector-concentrator electrodes for microchannel electrophoresis |
JP3744310B2 (ja) | 2000-04-13 | 2006-02-08 | 株式会社日立製作所 | 電気泳動装置 |
ATE432466T1 (de) * | 2000-10-31 | 2009-06-15 | Caliper Life Sciences Inc | Mikrofluidisches verfahren für in-situ- materialkonzentration |
US7070682B2 (en) * | 2001-01-16 | 2006-07-04 | Cheng Lee | Microfluidic apparatus for performing gel protein extractions and methods for using the apparatus |
KR100425536B1 (ko) * | 2001-07-16 | 2004-03-30 | 학교법인 포항공과대학교 | 유체 마이크로칩용 브레드보드 |
DE10136275C1 (de) * | 2001-07-25 | 2002-12-12 | Fraunhofer Ges Forschung | Verfahren und Vorrichtung zur Probentrennung |
JP2003066005A (ja) * | 2001-08-23 | 2003-03-05 | Kikuchi Jun | 細胞の電気泳動方法及び装置 |
JP2003149218A (ja) | 2001-11-08 | 2003-05-21 | Nano Solution:Kk | 2次元高速液体クロマトグラフ装置及びそれを用いた蛋白質分析装置 |
US6802967B2 (en) * | 2002-03-06 | 2004-10-12 | Shimadzu Corporation | Multi-dimension liquid chromatography separation system |
JP2004101477A (ja) | 2002-09-12 | 2004-04-02 | Yoshio Yamauchi | 2次元高速液体クロマトグラフ装置及びそれを用いた蛋白質分析装置 |
JP2004157096A (ja) * | 2002-11-02 | 2004-06-03 | Minoru Seki | 化学物質の二次元分離機構及びその装置 |
-
2004
- 2004-07-03 DE DE602004005843T patent/DE602004005843T2/de not_active Expired - Lifetime
- 2004-07-03 DE DE602004012326T patent/DE602004012326T2/de not_active Expired - Lifetime
- 2004-07-03 ES ES06013800T patent/ES2301118T3/es not_active Expired - Lifetime
- 2004-07-03 EP EP04015701A patent/EP1612550B1/de not_active Expired - Lifetime
- 2004-07-03 EP EP06013800A patent/EP1717580B1/de not_active Expired - Lifetime
- 2004-07-03 ES ES04015701T patent/ES2283907T3/es not_active Expired - Lifetime
- 2004-07-03 AT AT06013800T patent/ATE388397T1/de not_active IP Right Cessation
- 2004-07-03 AT AT04015701T patent/ATE359504T1/de not_active IP Right Cessation
-
2005
- 2005-06-28 US US11/169,103 patent/US7820023B2/en not_active Expired - Fee Related
- 2005-06-29 CA CA002511079A patent/CA2511079A1/en not_active Abandoned
- 2005-07-01 JP JP2005193598A patent/JP4527619B2/ja not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
ATE388397T1 (de) | 2008-03-15 |
JP2006017731A (ja) | 2006-01-19 |
US7820023B2 (en) | 2010-10-26 |
DE602004012326D1 (de) | 2008-04-17 |
ES2283907T3 (es) | 2007-11-01 |
EP1717580A2 (de) | 2006-11-02 |
EP1612550A1 (de) | 2006-01-04 |
EP1717580A3 (de) | 2006-12-13 |
JP4527619B2 (ja) | 2010-08-18 |
US20060086611A1 (en) | 2006-04-27 |
EP1717580B1 (de) | 2008-03-05 |
CA2511079A1 (en) | 2006-01-03 |
DE602004005843D1 (de) | 2007-05-24 |
DE602004012326T2 (de) | 2009-03-26 |
DE602004005843T2 (de) | 2007-08-30 |
EP1612550B1 (de) | 2007-04-11 |
ES2301118T3 (es) | 2008-06-16 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
Giordano et al. | On-line sample pre-concentration in microfluidic devices: A review | |
Wainright et al. | Sample pre-concentration by isotachophoresis in microfluidic devices | |
Graß et al. | A new PMMA-microchip device for isotachophoresis with integrated conductivity detector | |
US9039973B2 (en) | Hybrid digital and channel microfluidic devices and methods of use thereof | |
Shadpour et al. | Multichannel microchip electrophoresis device fabricated in polycarbonate with an integrated contact conductivity sensor array | |
US9728387B2 (en) | Solid phase extraction with capillary electrophoresis | |
JP2006017731A5 (de) | ||
ATE359504T1 (de) | Vorkonzentrierende verbindungstelle für die kupplung von flüssiger chromatographie und kapillarelektrophorese | |
Gong et al. | On-line sample preconcentration using field-amplified stacking injection in microchip capillary electrophoresis | |
Kato et al. | Rapid analysis of amino acids in Japanese green tea by microchip electrophoresis using plastic microchip and fluorescence detection | |
Wu et al. | Multi-dimension microchip-capillary electrophoresis device for determination of functional proteins in infant milk formula | |
Lin et al. | A poly-methylmethacrylate electrophoresis microchip with sample preconcentrator | |
Chen et al. | Flow-through sampling for electrophoresis-based microchips and their applications for protein analysis | |
Tachibana et al. | Robust and simple interface for microchip electrophoresis–mass spectrometry | |
Wu et al. | Sensitive analysis of amino acids and vitamin B3 in functional drinks via field-amplified stacking with reversed-field stacking in microchip electrophoresis | |
Pumera | Microfluidics in amino acid analysis | |
Gaspar et al. | Split injection: A simple introduction of subnanoliter sample volumes for chip electrophoresis | |
CN103055973A (zh) | 一种新型微流控分离芯片及其制备方法 | |
Jeong et al. | Transient isotachophoresis of highly saline samples using a microchip | |
Sheng et al. | Rapid ultraviolet monitoring of multiple psychotropic drugs with a renewable microfluidic device | |
EP2334432A1 (de) | Materialtrennvorrichtung | |
Kinde et al. | Electrophoretic extraction of low molecular weight cationic analytes from sodium dodecyl sulfate containing sample matrices for their direct electrospray ionization mass spectrometry | |
Sahlin | Two-dimensional capillary electrophoresis using tangentially connected capillaries | |
Silvertand et al. | Selective protein removal and desalting using microchip CE | |
Chun | Integration of electropreconcentration and electrospray ionization in a microchip |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
UEP | Publication of translation of european patent specification |
Ref document number: 1612550 Country of ref document: EP |
|
REN | Ceased due to non-payment of the annual fee |