ATE359273T1 - Amonafidsalze - Google Patents
AmonafidsalzeInfo
- Publication number
- ATE359273T1 ATE359273T1 AT03718511T AT03718511T ATE359273T1 AT E359273 T1 ATE359273 T1 AT E359273T1 AT 03718511 T AT03718511 T AT 03718511T AT 03718511 T AT03718511 T AT 03718511T AT E359273 T1 ATE359273 T1 AT E359273T1
- Authority
- AT
- Austria
- Prior art keywords
- sup
- sub
- independently
- alkyl group
- amonafide
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
- C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
- C07D221/04—Ortho- or peri-condensed ring systems
- C07D221/06—Ring systems of three rings
- C07D221/14—Aza-phenalenes, e.g. 1,8-naphthalimide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Lubricants (AREA)
- Separation Using Semi-Permeable Membranes (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10/128,129 US6693198B2 (en) | 2002-04-22 | 2002-04-22 | Amonafide salts |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE359273T1 true ATE359273T1 (de) | 2007-05-15 |
Family
ID=29248438
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT03718511T ATE359273T1 (de) | 2002-04-22 | 2003-04-22 | Amonafidsalze |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US6693198B2 (de) |
| EP (1) | EP1499595B1 (de) |
| JP (2) | JP4630518B2 (de) |
| AT (1) | ATE359273T1 (de) |
| AU (1) | AU2003221771B2 (de) |
| CA (1) | CA2482445A1 (de) |
| DE (1) | DE60313156T2 (de) |
| ES (1) | ES2287463T3 (de) |
| WO (1) | WO2003089415A1 (de) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20050239816A1 (en) * | 2002-04-22 | 2005-10-27 | Xanthus Life Sciences, Inc. | Amonafide salts |
| US6693198B2 (en) | 2002-04-22 | 2004-02-17 | Xanthus Life Sciences, Inc. | Amonafide salts |
| EP1539150A4 (de) * | 2002-07-08 | 2006-10-11 | Chemgenex Pharmaceuticals Inc | Naphthalimidsynthese, einschliesslich amonafid-synthese, und pharmazeutische zubereitungen daraus |
| AU2005209845A1 (en) * | 2004-01-30 | 2005-08-18 | Chemgenex Pharmaceuticals, Inc. | Naphthalimide dosing by N-acetyl transferase genotyping |
| BRPI0510719A (pt) * | 2004-05-05 | 2007-11-20 | Unibioscreen Sa | derivados de naftalimida, composição farmacêutica, uso e método de preparação dos mesmos |
| CA2569279A1 (en) * | 2004-06-04 | 2005-12-15 | Chemgenex Pharmaceuticals, Inc. | Methods of treating cellular proliferative disease using naphthalimide and parp-1 inhibitors |
| FR2898902B1 (fr) * | 2006-03-24 | 2010-09-10 | Oreal | Colorants particuliers de type naphtalimide, composition tinctoriale comprenant au moins un tel colorant, procede de mise en oeuvre et utilisations |
| ES2338193B8 (es) * | 2008-02-25 | 2011-07-19 | Centro Atlantico Del Medicamento, S.A. | Nuevas sales de amonafide. |
| CA2995880C (en) | 2009-01-16 | 2021-01-05 | Exelixis, Inc. | Processes for preparing n-(4-{[6,7-bis(methyloxy)quinolin-4-yl]oxy}phenyl)-n'-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide |
| CN102718709A (zh) * | 2011-03-30 | 2012-10-10 | 北京德众万全药物技术开发有限公司 | 一种制备氨萘非特的新方法 |
| CN109490291B (zh) * | 2018-11-20 | 2021-05-11 | 上海应用技术大学 | 基于吸电子基取代的1,8-萘酰亚胺类化合物作为氟离子的显色试剂的用途 |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES459497A1 (es) * | 1977-06-04 | 1978-04-16 | Made Labor Sa | Un metodo para la preparacion industrial de naftalimidas y sus derivados. |
| US4614820A (en) * | 1983-04-01 | 1986-09-30 | Warner-Lambert Co. | 3,6-disubstituted-1,8-naphthalimides |
| US4499266A (en) * | 1983-04-01 | 1985-02-12 | Warner-Lambert Company | 3,6-Dinitro-1,8-naphthalimides |
| US5183821A (en) | 1983-09-19 | 1993-02-02 | Laboratories Knoll, S.A. | Method for treating leukemias using N-(2-dimethylaminoethyl)-3-amino-1,8-naphthalimide for treating leukemias and solid tumors |
| US4665071A (en) | 1984-02-21 | 1987-05-12 | Warner-Lambert Company | 3,6-disubstituted-1,8-naphthalimides and methods for their production and use |
| DE3614414A1 (de) * | 1986-04-29 | 1987-11-05 | Knoll Ag | Neue benzo(de)isochinolin-1,3-dione, ihre herstellung und verwendung |
| DE3635711A1 (de) * | 1986-10-21 | 1988-04-28 | Knoll Ag | 5-nitrobenzo(de)isochinolin-1,3-dione, ihre herstellung und verwendung |
| US5420137A (en) | 1989-07-11 | 1995-05-30 | Knoll Ag | Amonafide salts |
| DE3922771A1 (de) * | 1989-07-11 | 1991-01-24 | Knoll Ag | Amonafide-salze |
| DE4106122A1 (de) * | 1991-02-27 | 1992-09-03 | Bayer Ag | Neue naphthalimide, diese enthaltende toner und die verwendung der neuen naphthalimide als additive fuer toner |
| AU760136B2 (en) * | 1998-11-25 | 2003-05-08 | Merck Patent Gmbh | Substituted benzo(DE)isoquinoline-1,3-diones |
| US6630173B2 (en) | 2000-04-12 | 2003-10-07 | Chemgenex Therapeutics, Inc. | Naphthalimide compositions and uses thereof |
| US6693198B2 (en) | 2002-04-22 | 2004-02-17 | Xanthus Life Sciences, Inc. | Amonafide salts |
-
2002
- 2002-04-22 US US10/128,129 patent/US6693198B2/en not_active Expired - Fee Related
- 2002-07-05 JP JP2002197809A patent/JP4630518B2/ja not_active Expired - Fee Related
-
2003
- 2003-04-22 CA CA002482445A patent/CA2482445A1/en not_active Abandoned
- 2003-04-22 DE DE60313156T patent/DE60313156T2/de not_active Expired - Lifetime
- 2003-04-22 AT AT03718511T patent/ATE359273T1/de not_active IP Right Cessation
- 2003-04-22 WO PCT/US2003/012619 patent/WO2003089415A1/en active IP Right Grant
- 2003-04-22 ES ES03718511T patent/ES2287463T3/es not_active Expired - Lifetime
- 2003-04-22 EP EP03718511A patent/EP1499595B1/de not_active Expired - Lifetime
- 2003-04-22 AU AU2003221771A patent/AU2003221771B2/en not_active Ceased
- 2003-10-20 US US10/690,458 patent/US6989390B2/en not_active Expired - Fee Related
-
2009
- 2009-08-27 JP JP2009197462A patent/JP2010006831A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| US6693198B2 (en) | 2004-02-17 |
| US20030203932A1 (en) | 2003-10-30 |
| DE60313156T2 (de) | 2007-12-13 |
| EP1499595B1 (de) | 2007-04-11 |
| AU2003221771B2 (en) | 2007-02-15 |
| JP2003321452A (ja) | 2003-11-11 |
| AU2003221771A1 (en) | 2003-11-03 |
| WO2003089415A1 (en) | 2003-10-30 |
| CA2482445A1 (en) | 2003-10-30 |
| EP1499595A1 (de) | 2005-01-26 |
| US6989390B2 (en) | 2006-01-24 |
| JP4630518B2 (ja) | 2011-02-09 |
| JP2010006831A (ja) | 2010-01-14 |
| US20040132763A1 (en) | 2004-07-08 |
| ES2287463T3 (es) | 2007-12-16 |
| DE60313156D1 (de) | 2007-05-24 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |