ATE358525T1 - Fraktionierung mittels dielektrophoresis und fraktionierung unter anwendung eines flussfeldes - Google Patents
Fraktionierung mittels dielektrophoresis und fraktionierung unter anwendung eines flussfeldesInfo
- Publication number
- ATE358525T1 ATE358525T1 AT97904207T AT97904207T ATE358525T1 AT E358525 T1 ATE358525 T1 AT E358525T1 AT 97904207 T AT97904207 T AT 97904207T AT 97904207 T AT97904207 T AT 97904207T AT E358525 T1 ATE358525 T1 AT E358525T1
- Authority
- AT
- Austria
- Prior art keywords
- matter
- chamber
- fractionation
- fluid
- dielectrophoresis
- Prior art date
Links
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B03—SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
- B03C—MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
- B03C5/00—Separating dispersed particles from liquids by electrostatic effect
- B03C5/02—Separators
- B03C5/022—Non-uniform field separators
- B03C5/028—Non-uniform field separators using travelling electric fields, i.e. travelling wave dielectrophoresis [TWD]
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B03—SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
- B03C—MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
- B03C5/00—Separating dispersed particles from liquids by electrostatic effect
- B03C5/005—Dielectrophoresis, i.e. dielectric particles migrating towards the region of highest field strength
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/0005—Field flow fractionation
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/0005—Field flow fractionation
- G01N2030/0015—Field flow fractionation characterised by driving force
- G01N2030/002—Field flow fractionation characterised by driving force sedimentation or centrifugal FFF
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/0005—Field flow fractionation
- G01N2030/0015—Field flow fractionation characterised by driving force
- G01N2030/0035—Field flow fractionation characterised by driving force electrical field
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/0005—Field flow fractionation
- G01N2030/004—Field flow fractionation characterised by opposing force
- G01N2030/0065—Dielectric FFF, i.e. opposing forces dominate hydrodynamic lift forces and steric effects
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Electrochemistry (AREA)
- Molecular Biology (AREA)
- Analytical Chemistry (AREA)
- Physics & Mathematics (AREA)
- Biochemistry (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Investigating Or Analyzing Materials By The Use Of Electric Means (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Steroid Compounds (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Electrostatic Separation (AREA)
- Treatment Of Liquids With Adsorbents In General (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US1090496P | 1996-01-31 | 1996-01-31 | |
US08/604,779 US5993630A (en) | 1996-01-31 | 1996-02-23 | Method and apparatus for fractionation using conventional dielectrophoresis and field flow fractionation |
US08/605,535 US5888370A (en) | 1996-02-23 | 1996-02-23 | Method and apparatus for fractionation using generalized dielectrophoresis and field flow fractionation |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE358525T1 true ATE358525T1 (de) | 2007-04-15 |
Family
ID=27359327
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT97904207T ATE358525T1 (de) | 1996-01-31 | 1997-01-31 | Fraktionierung mittels dielektrophoresis und fraktionierung unter anwendung eines flussfeldes |
Country Status (7)
Country | Link |
---|---|
EP (1) | EP0885055B1 (de) |
JP (1) | JP2000505545A (de) |
AT (1) | ATE358525T1 (de) |
AU (1) | AU729224B2 (de) |
CA (1) | CA2245514C (de) |
DE (1) | DE69737552T2 (de) |
WO (1) | WO1997027933A1 (de) |
Families Citing this family (41)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6641708B1 (en) * | 1996-01-31 | 2003-11-04 | Board Of Regents, The University Of Texas System | Method and apparatus for fractionation using conventional dielectrophoresis and field flow fractionation |
CN1181337C (zh) | 2000-08-08 | 2004-12-22 | 清华大学 | 微流体系统中实体分子的操纵方法及相关试剂盒 |
WO2000073780A1 (en) * | 1999-05-28 | 2000-12-07 | Proteologics, Inc. | Methods and apparatus for nonlinear mobility electrophoresis separation |
GB9916848D0 (en) * | 1999-07-20 | 1999-09-22 | Univ Wales Bangor | Travelling wave dielectrophoretic apparatus and method |
EP1108473A1 (de) * | 1999-12-16 | 2001-06-20 | Prior Engineering Ag | Apparat und Verfahren für Trennung durch Dielektrophoresis |
AU3160301A (en) * | 1999-12-16 | 2001-06-25 | Prior Engineering Ag | Device and method for separating particles by dielectrophoresis |
US6537433B1 (en) | 2000-03-10 | 2003-03-25 | Applera Corporation | Methods and apparatus for the location and concentration of polar analytes using an alternating electric field |
CN100495030C (zh) | 2000-09-30 | 2009-06-03 | 清华大学 | 多力操纵装置及其应用 |
CN100494360C (zh) * | 2001-03-22 | 2009-06-03 | 博奥生物有限公司 | 细胞分离方法及其应用 |
JP4779261B2 (ja) * | 2001-08-30 | 2011-09-28 | パナソニック株式会社 | 微粒子分離方法、微粒子分離装置、およびセンサ |
US7060798B2 (en) | 2002-05-13 | 2006-06-13 | State Of Oregon Acting By And Through The Oregon State Board Of Higher Education On Behalf Of Oregon State University | Modified protein adhesives and lignocellulosic composites made from the adhesives |
US7147764B2 (en) | 2003-03-28 | 2006-12-12 | Applera Corporation | Dual electrode injection of analyte into a capillary electrophoretic device |
US7169282B2 (en) * | 2003-05-13 | 2007-01-30 | Aura Biosystems Inc. | Dielectrophoresis apparatus |
JP2005334865A (ja) * | 2004-01-19 | 2005-12-08 | Hiroshima Univ | 固体微粒子分級装置及びこれを利用した固体微粒子分級方法 |
CA2552262C (en) | 2004-02-02 | 2016-04-19 | The University Of British Columbia | Scodaphoresis and methods and apparatus for moving and concentrating particles |
US8529744B2 (en) | 2004-02-02 | 2013-09-10 | Boreal Genomics Corp. | Enrichment of nucleic acid targets |
US10337054B2 (en) | 2004-02-02 | 2019-07-02 | Quantum-Si Incorporated | Enrichment of nucleic acid targets |
US9186685B2 (en) | 2012-01-13 | 2015-11-17 | The University Of British Columbia | Multiple arm apparatus and methods for separation of particles |
US8518228B2 (en) | 2011-05-20 | 2013-08-27 | The University Of British Columbia | Systems and methods for enhanced SCODA |
US7160425B2 (en) * | 2004-03-25 | 2007-01-09 | Hewlett-Packard Development Company, L.P. | Cell transporter for a biodevice |
EP1765501A1 (de) | 2004-05-28 | 2007-03-28 | Board of Regents, The University of Texas System | Programmierbare fluidverarbeiter |
EP1621877A1 (de) * | 2004-07-30 | 2006-02-01 | Julius-Maximilians-Universität Würzburg | Verfahren zur Kontaktierung von Elektrodenkammes |
US7811438B2 (en) * | 2004-12-08 | 2010-10-12 | Palo Alto Research Center Incorporated | Bio-enrichment device to enhance sample collection and detection |
CA2496294A1 (en) | 2005-02-07 | 2006-08-07 | The University Of British Columbia | Apparatus and methods for concentrating and separating particles such as molecules |
JP2008263847A (ja) * | 2007-04-19 | 2008-11-06 | Gunma Univ | 細胞分離装置および細胞分離方法 |
US8475641B2 (en) | 2008-02-01 | 2013-07-02 | The University Of British Columbia | Methods and apparatus for particle introduction and recovery |
JP5333752B2 (ja) * | 2009-03-27 | 2013-11-06 | セイコーエプソン株式会社 | 細胞分離装置および細胞分離方法 |
US8343440B2 (en) | 2009-03-27 | 2013-01-01 | Seiko Epson Corporation | Cell separating apparatus and cell separating method |
JP2010252785A (ja) | 2009-03-31 | 2010-11-11 | Kanagawa Acad Of Sci & Technol | 細胞濃縮分離装置 |
WO2010121381A1 (en) | 2009-04-21 | 2010-10-28 | The University Of British Columbia | System and methods for detection of particles |
WO2013166444A2 (en) | 2012-05-04 | 2013-11-07 | Boreal Genomics Corp. | Biomarker analysis using scodaphoresis |
US9340835B2 (en) | 2013-03-15 | 2016-05-17 | Boreal Genomics Corp. | Method for separating homoduplexed and heteroduplexed nucleic acids |
JP5780274B2 (ja) * | 2013-07-31 | 2015-09-16 | セイコーエプソン株式会社 | 細胞回収方法 |
US10928404B2 (en) | 2014-02-26 | 2021-02-23 | The Brigham And Women's Hospital, Inc. | System and method for cell levitation and monitoring |
JP6598253B2 (ja) * | 2015-05-18 | 2019-10-30 | 株式会社Humanix | 1細胞あるいは超微小域分子の電場捕獲・遊離分離・分子検出法 |
US11130986B2 (en) | 2015-05-20 | 2021-09-28 | Quantum-Si Incorporated | Method for isolating target nucleic acid using heteroduplex binding proteins |
JP6808960B2 (ja) * | 2016-04-15 | 2021-01-06 | 東京エレクトロン株式会社 | 処理液供給装置 |
CN110506201B (zh) * | 2017-02-10 | 2022-11-29 | 东曹株式会社 | 粒子检测装置和粒子检测方法 |
DE112018004857B4 (de) | 2017-08-23 | 2024-03-28 | Istanbul Teknik Universitesi | Mikrofluidisches system für krebszellen-separation, -erfassung und -medikamentscreening-analysen |
DE102018105931A1 (de) * | 2018-03-14 | 2019-09-19 | Technische Universität Darmstadt | Mikrowellenporator |
DE102018210693A1 (de) | 2018-06-29 | 2020-01-02 | Robert Bosch Gmbh | Vorrichtung und Verfahren zur dielektrischen Trennung von Partikeln |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4001102A (en) * | 1973-04-06 | 1977-01-04 | The Carborundum Company | Process for generating periodic non-uniform electric field, and for removing polarizable particulate material from fluid, using ferroelectric apparatus |
SU474723A1 (ru) * | 1973-06-04 | 1975-06-25 | Институт биологической физики АН СССР | Устройство разделени дисперсных частиц |
US4326934A (en) * | 1979-12-31 | 1982-04-27 | Pohl Herbert A | Continuous dielectrophoretic cell classification method |
US4440638A (en) * | 1982-02-16 | 1984-04-03 | U.T. Board Of Regents | Surface field-effect device for manipulation of charged species |
US5344535A (en) * | 1989-11-27 | 1994-09-06 | British Technology Group Limited | Dielectrophoretic characterization of micro-organisms and other particles |
DE4127405C2 (de) * | 1991-08-19 | 1996-02-29 | Fraunhofer Ges Forschung | Verfahren zur Trennung von Gemischen mikroskopisch kleiner, in einer Flüssigkeit oder einem Gel suspendierter dielektrischer Teilchen und Vorrichtung zur Durchführung des Verfahrens |
GB9208357D0 (en) * | 1992-04-16 | 1992-06-03 | British Tech Group | Apparatus for separating a mixture |
US5489506A (en) * | 1992-10-26 | 1996-02-06 | Biolife Systems, Inc. | Dielectrophoretic cell stream sorter |
-
1997
- 1997-01-31 AU AU18560/97A patent/AU729224B2/en not_active Ceased
- 1997-01-31 DE DE69737552T patent/DE69737552T2/de not_active Expired - Lifetime
- 1997-01-31 JP JP09527896A patent/JP2000505545A/ja not_active Ceased
- 1997-01-31 WO PCT/US1997/001746 patent/WO1997027933A1/en active IP Right Grant
- 1997-01-31 CA CA002245514A patent/CA2245514C/en not_active Expired - Fee Related
- 1997-01-31 AT AT97904207T patent/ATE358525T1/de not_active IP Right Cessation
- 1997-01-31 EP EP97904207A patent/EP0885055B1/de not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
CA2245514A1 (en) | 1997-08-07 |
AU729224B2 (en) | 2001-01-25 |
EP0885055B1 (de) | 2007-04-04 |
EP0885055A1 (de) | 1998-12-23 |
DE69737552T2 (de) | 2007-12-13 |
DE69737552D1 (de) | 2007-05-16 |
JP2000505545A (ja) | 2000-05-09 |
EP0885055A4 (de) | 1999-04-14 |
CA2245514C (en) | 2006-05-23 |
WO1997027933A1 (en) | 1997-08-07 |
AU1856097A (en) | 1997-08-22 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |