ATE346837T1 - Verfahren zur herstellung des inneren salzes von (r)- or (s)-aminocarnitin, salze und derivate davon - Google Patents
Verfahren zur herstellung des inneren salzes von (r)- or (s)-aminocarnitin, salze und derivate davonInfo
- Publication number
- ATE346837T1 ATE346837T1 AT02767834T AT02767834T ATE346837T1 AT E346837 T1 ATE346837 T1 AT E346837T1 AT 02767834 T AT02767834 T AT 02767834T AT 02767834 T AT02767834 T AT 02767834T AT E346837 T1 ATE346837 T1 AT E346837T1
- Authority
- AT
- Austria
- Prior art keywords
- aminocarnitine
- derivatives
- salts
- inner salt
- preparing
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C227/14—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof
- C07C227/16—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof by reactions not involving the amino or carboxyl groups
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C231/00—Preparation of carboxylic acid amides
- C07C231/02—Preparation of carboxylic acid amides from carboxylic acids or from esters, anhydrides, or halides thereof by reaction with ammonia or amines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C273/00—Preparation of urea or its derivatives, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
- C07C273/18—Preparation of urea or its derivatives, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups of substituted ureas
- C07C273/1809—Preparation of urea or its derivatives, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups of substituted ureas with formation of the N-C(O)-N moiety
- C07C273/1818—Preparation of urea or its derivatives, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups of substituted ureas with formation of the N-C(O)-N moiety from -N=C=O and XNR'R"
- C07C273/1827—X being H
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Health & Medical Sciences (AREA)
- Diabetes (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Obesity (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Endocrinology (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Emergency Medicine (AREA)
- Hematology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT2001RM000456A ITRM20010456A1 (it) | 2001-07-26 | 2001-07-26 | Procedimento per la preparazione di (r)- o (s)- amminocarnitina sale interno, dei suoi sali e dei suoi derivati. |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE346837T1 true ATE346837T1 (de) | 2006-12-15 |
Family
ID=11455694
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT02767834T ATE346837T1 (de) | 2001-07-26 | 2002-07-17 | Verfahren zur herstellung des inneren salzes von (r)- or (s)-aminocarnitin, salze und derivate davon |
Country Status (19)
| Country | Link |
|---|---|
| US (1) | US6953865B2 (de) |
| EP (1) | EP1409448B1 (de) |
| JP (1) | JP4212473B2 (de) |
| KR (1) | KR100879125B1 (de) |
| CN (1) | CN1231460C (de) |
| AT (1) | ATE346837T1 (de) |
| AU (1) | AU2002330738B2 (de) |
| CA (1) | CA2453019A1 (de) |
| CY (1) | CY1107567T1 (de) |
| DE (1) | DE60216466T2 (de) |
| DK (1) | DK1409448T3 (de) |
| ES (1) | ES2280570T3 (de) |
| HK (1) | HK1068327A1 (de) |
| HU (1) | HUP0401617A3 (de) |
| IT (1) | ITRM20010456A1 (de) |
| MX (1) | MXPA04000676A (de) |
| PL (1) | PL367614A1 (de) |
| PT (1) | PT1409448E (de) |
| WO (1) | WO2003010129A1 (de) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1299266B1 (it) * | 1998-05-15 | 2000-02-29 | Sigma Tau Ind Farmaceuti | Inibitori reversibili della carnitina palmitoil trasferasi |
| US7776915B2 (en) * | 2005-03-24 | 2010-08-17 | Tracie Martyn International, Llc | Topical formulations and methods of use |
| WO2008109991A1 (en) * | 2007-03-09 | 2008-09-18 | University Health Network | Inhibitors of carnitine palmitoyltransferase and treating cancer |
| US8680282B2 (en) | 2007-08-01 | 2014-03-25 | University Health Network | Cyclic inhibitors of carnitine palmitoyltransferase and treating cancer |
| CN111621541A (zh) * | 2019-02-27 | 2020-09-04 | 上海艾美晶生物科技有限公司 | 使用电渗析技术拆分光学异构体的方法 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4767781A (en) * | 1981-11-26 | 1988-08-30 | Takeda Chemical Industries, Ltd. | Derivatives of beta-amino-gamma-trimethylammonio-butyrate and their production and use |
| IT1261489B (it) * | 1993-07-29 | 1996-05-23 | Sigma Tau Ind Farmaceuti | Procedimento per la produzione di r amminocarnitina e s amminocarnitina. |
| IT1299266B1 (it) * | 1998-05-15 | 2000-02-29 | Sigma Tau Ind Farmaceuti | Inibitori reversibili della carnitina palmitoil trasferasi |
| IT1306184B1 (it) * | 1999-08-05 | 2001-05-30 | Sigma Tau Ind Farmaceuti | Nitrilossi derivati della (r) e (s)-carnitina. |
-
2001
- 2001-07-26 IT IT2001RM000456A patent/ITRM20010456A1/it unknown
-
2002
- 2002-07-17 EP EP02767834A patent/EP1409448B1/de not_active Expired - Lifetime
- 2002-07-17 US US10/482,729 patent/US6953865B2/en not_active Expired - Fee Related
- 2002-07-17 CA CA002453019A patent/CA2453019A1/en not_active Abandoned
- 2002-07-17 KR KR1020037017244A patent/KR100879125B1/ko not_active IP Right Cessation
- 2002-07-17 DK DK02767834T patent/DK1409448T3/da active
- 2002-07-17 MX MXPA04000676A patent/MXPA04000676A/es active IP Right Grant
- 2002-07-17 PL PL02367614A patent/PL367614A1/xx unknown
- 2002-07-17 JP JP2003515489A patent/JP4212473B2/ja not_active Expired - Fee Related
- 2002-07-17 AU AU2002330738A patent/AU2002330738B2/en not_active Ceased
- 2002-07-17 CN CNB028140222A patent/CN1231460C/zh not_active Expired - Fee Related
- 2002-07-17 AT AT02767834T patent/ATE346837T1/de not_active IP Right Cessation
- 2002-07-17 WO PCT/IT2002/000468 patent/WO2003010129A1/en active IP Right Grant
- 2002-07-17 ES ES02767834T patent/ES2280570T3/es not_active Expired - Lifetime
- 2002-07-17 DE DE60216466T patent/DE60216466T2/de not_active Expired - Lifetime
- 2002-07-17 PT PT02767834T patent/PT1409448E/pt unknown
- 2002-07-17 HU HU0401617A patent/HUP0401617A3/hu unknown
-
2005
- 2005-01-13 HK HK05100341A patent/HK1068327A1/xx not_active IP Right Cessation
-
2007
- 2007-02-26 CY CY20071100269T patent/CY1107567T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| KR100879125B1 (ko) | 2009-01-19 |
| WO2003010129A1 (en) | 2003-02-06 |
| ITRM20010456A1 (it) | 2003-01-27 |
| MXPA04000676A (es) | 2004-04-05 |
| DE60216466T2 (de) | 2007-09-20 |
| PL367614A1 (en) | 2005-03-07 |
| AU2002330738B2 (en) | 2008-05-08 |
| DE60216466D1 (de) | 2007-01-11 |
| ES2280570T3 (es) | 2007-09-16 |
| JP4212473B2 (ja) | 2009-01-21 |
| US20040171875A1 (en) | 2004-09-02 |
| DK1409448T3 (da) | 2007-04-02 |
| KR20040032116A (ko) | 2004-04-14 |
| ITRM20010456A0 (it) | 2001-07-26 |
| JP2004536867A (ja) | 2004-12-09 |
| CY1107567T1 (el) | 2013-03-13 |
| CN1527811A (zh) | 2004-09-08 |
| US6953865B2 (en) | 2005-10-11 |
| CN1231460C (zh) | 2005-12-14 |
| PT1409448E (pt) | 2007-02-28 |
| EP1409448A1 (de) | 2004-04-21 |
| HK1068327A1 (en) | 2005-04-29 |
| EP1409448B1 (de) | 2006-11-29 |
| CA2453019A1 (en) | 2003-02-06 |
| HUP0401617A2 (hu) | 2004-12-28 |
| HUP0401617A3 (en) | 2008-05-28 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
Ref document number: 1409448 Country of ref document: EP |
|
| REN | Ceased due to non-payment of the annual fee |