ATE345137T1 - Verwendung von 2h-(1,3)-oxazino(3,2-a)indol- derivaten zur behandlung von neuropathischem schmerz - Google Patents

Verwendung von 2h-(1,3)-oxazino(3,2-a)indol- derivaten zur behandlung von neuropathischem schmerz

Info

Publication number
ATE345137T1
ATE345137T1 AT04740899T AT04740899T ATE345137T1 AT E345137 T1 ATE345137 T1 AT E345137T1 AT 04740899 T AT04740899 T AT 04740899T AT 04740899 T AT04740899 T AT 04740899T AT E345137 T1 ATE345137 T1 AT E345137T1
Authority
AT
Austria
Prior art keywords
oxazino
treatment
neuropathic pain
indole derivatives
indole
Prior art date
Application number
AT04740899T
Other languages
English (en)
Inventor
Angelo Guglielmotti
Lorenzo Polenzani
Alessandra Alisi
Nicola Cazzolla
Original Assignee
Acraf
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Acraf filed Critical Acraf
Application granted granted Critical
Publication of ATE345137T1 publication Critical patent/ATE345137T1/de

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5365Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines ortho- or peri-condensed with heterocyclic ring systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Indole Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Medicinal Preparation (AREA)
AT04740899T 2003-07-18 2004-07-08 Verwendung von 2h-(1,3)-oxazino(3,2-a)indol- derivaten zur behandlung von neuropathischem schmerz ATE345137T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT001467A ITMI20031467A1 (it) 2003-07-18 2003-07-18 Farmaco attivo nel dolore neuropatico

Publications (1)

Publication Number Publication Date
ATE345137T1 true ATE345137T1 (de) 2006-12-15

Family

ID=34131193

Family Applications (1)

Application Number Title Priority Date Filing Date
AT04740899T ATE345137T1 (de) 2003-07-18 2004-07-08 Verwendung von 2h-(1,3)-oxazino(3,2-a)indol- derivaten zur behandlung von neuropathischem schmerz

Country Status (21)

Country Link
US (1) US20060211691A1 (de)
EP (1) EP1646391B1 (de)
JP (1) JP2006528142A (de)
KR (1) KR20060033784A (de)
CN (1) CN100409850C (de)
AR (1) AR045993A1 (de)
AT (1) ATE345137T1 (de)
AU (1) AU2004262876B2 (de)
CA (1) CA2526852C (de)
DE (1) DE602004003252T2 (de)
DK (1) DK1646391T3 (de)
EA (1) EA008927B1 (de)
ES (1) ES2276317T3 (de)
GE (1) GEP20084307B (de)
HK (1) HK1087027A1 (de)
IL (1) IL172156A0 (de)
IT (1) ITMI20031467A1 (de)
PL (1) PL1646391T3 (de)
PT (1) PT1646391E (de)
UA (1) UA81050C2 (de)
WO (1) WO2005014001A1 (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101103157B1 (ko) * 2006-12-26 2012-01-04 다이호야쿠힌고교 가부시키가이샤 당뇨병성 뉴로퍼시 치료제
DE102007058504A1 (de) 2007-12-05 2009-07-09 Acino Ag Transdermales therapeutisches System mit einem Gehalt an einem Modulator für nikotinische Acetylcholinrezeptoren (nAChR)

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5189041A (en) * 1990-11-16 1993-02-23 Syntex (U.S.A.) Inc. Tricyclic 5-ht3 receptor antagonists
GB9120628D0 (en) * 1991-09-27 1991-11-06 Fujisawa Pharmaceutical Co Pyrrolobenzoxazine derivatives and process for preparation thereof
PT884319E (pt) * 1992-03-12 2004-09-30 Smithkline Beecham Plc N-¬(1-n-butil-4-piperidil)metil|-3,4-di-hidro-2h-¬1,3|oxazino¬3,2-a|indole-10-carboxamida ou um seu sal farmaceuticamente aceitavel
IL117438A (en) * 1995-03-16 2001-12-23 Lilly Co Eli Indazolecarboxamides, their preparation and pharmaceutical compositions containing them
EP1200086A4 (de) * 1999-08-04 2009-05-27 Icagen Inc Methoden zur behandlung oder vorbeugung von schmerzen und angstzuständen
US20040038874A1 (en) * 2002-08-22 2004-02-26 Osemwota Omoigui Method of treatment of persistent pain

Also Published As

Publication number Publication date
AU2004262876A1 (en) 2005-02-17
EP1646391B1 (de) 2006-11-15
CA2526852A1 (en) 2005-02-17
DE602004003252T2 (de) 2007-05-03
HK1087027A1 (en) 2006-10-06
PT1646391E (pt) 2007-01-31
CN100409850C (zh) 2008-08-13
ES2276317T3 (es) 2007-06-16
EP1646391A1 (de) 2006-04-19
AR045993A1 (es) 2005-11-23
AU2004262876B2 (en) 2010-05-20
JP2006528142A (ja) 2006-12-14
GEP20084307B (en) 2008-02-11
ITMI20031467A1 (it) 2005-01-19
CA2526852C (en) 2011-08-30
EA200600270A1 (ru) 2006-06-30
WO2005014001A9 (en) 2005-05-26
KR20060033784A (ko) 2006-04-19
PL1646391T3 (pl) 2007-04-30
IL172156A0 (en) 2006-04-10
CN1809361A (zh) 2006-07-26
US20060211691A1 (en) 2006-09-21
UA81050C2 (en) 2007-11-26
WO2005014001A1 (en) 2005-02-17
DK1646391T3 (da) 2007-03-19
DE602004003252D1 (de) 2006-12-28
EA008927B1 (ru) 2007-08-31

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