ATE344052T1 - Protein-verabreichungssystem, das dem menschlichen papillomavirus ähnliche partikel benützt. - Google Patents
Protein-verabreichungssystem, das dem menschlichen papillomavirus ähnliche partikel benützt.Info
- Publication number
- ATE344052T1 ATE344052T1 AT99940951T AT99940951T ATE344052T1 AT E344052 T1 ATE344052 T1 AT E344052T1 AT 99940951 T AT99940951 T AT 99940951T AT 99940951 T AT99940951 T AT 99940951T AT E344052 T1 ATE344052 T1 AT E344052T1
- Authority
- AT
- Austria
- Prior art keywords
- protein
- delivery system
- papilloma virus
- human papilloma
- protein delivery
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/86—Viral vectors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/20011—Papillomaviridae
- C12N2710/20022—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/20011—Papillomaviridae
- C12N2710/20023—Virus like particles [VLP]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2830/00—Vector systems having a special element relevant for transcription
- C12N2830/001—Vector systems having a special element relevant for transcription controllable enhancer/promoter combination
- C12N2830/002—Vector systems having a special element relevant for transcription controllable enhancer/promoter combination inducible enhancer/promoter combination, e.g. hypoxia, iron, transcription factor
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2830/00—Vector systems having a special element relevant for transcription
- C12N2830/70—Vector systems having a special element relevant for transcription from fungi
- C12N2830/702—Vector systems having a special element relevant for transcription from fungi yeast
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Virology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Zoology (AREA)
- Molecular Biology (AREA)
- Wood Science & Technology (AREA)
- Biophysics (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- Plant Pathology (AREA)
- Physics & Mathematics (AREA)
- Microbiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US9663898P | 1998-08-14 | 1998-08-14 |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE344052T1 true ATE344052T1 (de) | 2006-11-15 |
Family
ID=22258340
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT99940951T ATE344052T1 (de) | 1998-08-14 | 1999-08-10 | Protein-verabreichungssystem, das dem menschlichen papillomavirus ähnliche partikel benützt. |
Country Status (8)
Country | Link |
---|---|
EP (1) | EP1105157B1 (de) |
JP (1) | JP4563582B2 (de) |
AT (1) | ATE344052T1 (de) |
AU (1) | AU753391B2 (de) |
CA (1) | CA2339324C (de) |
DE (1) | DE69933875T2 (de) |
ES (1) | ES2275350T3 (de) |
WO (1) | WO2000009157A1 (de) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1187928B1 (de) * | 1999-06-30 | 2007-05-23 | Evotec AG | Virusähnliche partikel, vorbereitung und verwendung in screening und funktionelle genomanwendung |
US20040014033A1 (en) | 1999-06-30 | 2004-01-22 | Evotec Biosystems Ag, A Corporation Of Germany | Virus like particles, their preparation and their use preferably in pharmaceutical screening and functional genomics |
US7476517B2 (en) | 1999-06-30 | 2009-01-13 | Evotec Ag | Virus like particles, their preparation and their use preferably in pharmaceutical screening and functional genomics |
GB0007231D0 (en) * | 2000-03-24 | 2000-05-17 | Chiron Spa | Modified rna for gene delivery |
ES2323634T5 (es) * | 2002-05-17 | 2012-09-04 | University Of Cape Town | Proteínas quiméricas l1 del virus del papiloma humano 16 que contienen un péptido l2, partículas tipo virus preparadas a partir de estas proteínas y un método para preparar las partículas |
MXPA05010285A (es) * | 2003-03-24 | 2005-11-17 | Merck & Co Inc | Expresion optimizada de hpv 31 l1 en levadura. |
MY140664A (en) * | 2003-09-29 | 2010-01-15 | Merck Sharp & Dohme | Optimized expression of hpv 45 l1 in yeast |
MY139500A (en) | 2003-11-12 | 2009-10-30 | Merck Sharp & Dohme | Optimized expression of hpv 58 l1 in yeast |
EP1730175B1 (de) | 2004-03-24 | 2010-04-28 | Merck Sharp & Dohme Corp. | Optimierte expression von hpv-52-l1 in hefe |
WO2011151333A1 (en) * | 2010-06-02 | 2011-12-08 | Deutsches Krebsforschungszentrum | Papillomavirus l2 c-terminal peptides for vaccination |
WO2017106822A1 (en) | 2015-12-17 | 2017-06-22 | The Penn State Research Foundation | Paramyxovirus virus-like particles as protein delivery vehicles |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5618536A (en) * | 1992-09-03 | 1997-04-08 | The United States Of America As Represented By The Department Of Health And Human Services | Chimeric papillomavirus-like particles |
US5437951A (en) * | 1992-09-03 | 1995-08-01 | The United States Of America As Represented By The Department Of Health And Human Services | Self-assembling recombinant papillomavirus capsid proteins |
DE4447664C2 (de) * | 1994-10-07 | 1999-04-15 | Lutz Prof Dr Gissmann | Fusionsproteine, Verfahren zu deren Herstellung sowie deren Anwendung |
WO1996011272A2 (de) * | 1994-10-07 | 1996-04-18 | Medigene Gesellschaft Für Molekularbiologische Diagnostik, Theraphie Und Technologie Mbh | Papillomavirusähnliche partikel, fusionsproteine sowie verfahren zu deren herstellung |
JP3958360B2 (ja) * | 1995-02-24 | 2007-08-15 | キャンタブ ファーマシューティカルズ リサーチ リミティド | 免疫治療剤として役立つポリペプチド及びポリペプチド調製の方法 |
GB9621091D0 (en) * | 1996-10-09 | 1996-11-27 | Fondation Pour Le Perfectionem | Attenuated microorganisms strains and their uses |
-
1999
- 1999-08-10 JP JP2000564659A patent/JP4563582B2/ja not_active Expired - Lifetime
- 1999-08-10 EP EP99940951A patent/EP1105157B1/de not_active Expired - Lifetime
- 1999-08-10 AT AT99940951T patent/ATE344052T1/de not_active IP Right Cessation
- 1999-08-10 AU AU54699/99A patent/AU753391B2/en not_active Expired
- 1999-08-10 CA CA2339324A patent/CA2339324C/en not_active Expired - Lifetime
- 1999-08-10 DE DE69933875T patent/DE69933875T2/de not_active Expired - Lifetime
- 1999-08-10 WO PCT/US1999/017931 patent/WO2000009157A1/en active IP Right Grant
- 1999-08-10 ES ES99940951T patent/ES2275350T3/es not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
CA2339324A1 (en) | 2000-02-24 |
AU753391B2 (en) | 2002-10-17 |
CA2339324C (en) | 2011-05-31 |
EP1105157B1 (de) | 2006-11-02 |
JP2002522056A (ja) | 2002-07-23 |
EP1105157A4 (de) | 2004-12-08 |
DE69933875T2 (de) | 2007-05-31 |
WO2000009157A1 (en) | 2000-02-24 |
ES2275350T3 (es) | 2007-06-01 |
AU5469999A (en) | 2000-03-06 |
EP1105157A1 (de) | 2001-06-13 |
DE69933875D1 (de) | 2006-12-14 |
JP4563582B2 (ja) | 2010-10-13 |
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Legal Events
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RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |