ATE336240T1 - Therapeutische verwendung von stickstoffmonoxydinhibitoren - Google Patents

Therapeutische verwendung von stickstoffmonoxydinhibitoren

Info

Publication number
ATE336240T1
ATE336240T1 AT97952182T AT97952182T ATE336240T1 AT E336240 T1 ATE336240 T1 AT E336240T1 AT 97952182 T AT97952182 T AT 97952182T AT 97952182 T AT97952182 T AT 97952182T AT E336240 T1 ATE336240 T1 AT E336240T1
Authority
AT
Austria
Prior art keywords
tissue
inhibitor
cells
population
bone marrow
Prior art date
Application number
AT97952182T
Other languages
English (en)
Inventor
Grigori Enikolopov
Natalia I Peunova
Boris Kuzin
Hollis Cline
Tatiyana Michurina
Original Assignee
Cold Spring Harbor Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cold Spring Harbor Lab filed Critical Cold Spring Harbor Lab
Application granted granted Critical
Publication of ATE336240T1 publication Critical patent/ATE336240T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/17—Amides, e.g. hydroxamic acids having the group >N—C(O)—N< or >N—C(S)—N<, e.g. urea, thiourea, carmustine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/216—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acids having aromatic rings, e.g. benactizyne, clofibrate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A61K31/223—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of alpha-aminoacids

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Emergency Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
AT97952182T 1996-11-13 1997-11-13 Therapeutische verwendung von stickstoffmonoxydinhibitoren ATE336240T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US3069096P 1996-11-13 1996-11-13
US4541197P 1997-05-02 1997-05-02

Publications (1)

Publication Number Publication Date
ATE336240T1 true ATE336240T1 (de) 2006-09-15

Family

ID=26706342

Family Applications (1)

Application Number Title Priority Date Filing Date
AT97952182T ATE336240T1 (de) 1996-11-13 1997-11-13 Therapeutische verwendung von stickstoffmonoxydinhibitoren

Country Status (7)

Country Link
US (2) US5977181A (de)
EP (1) EP0952828B1 (de)
AT (1) ATE336240T1 (de)
AU (1) AU5585598A (de)
CA (1) CA2271729A1 (de)
DE (1) DE69736526T2 (de)
WO (1) WO1998020865A2 (de)

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6593372B2 (en) 1996-11-13 2003-07-15 Cold Spring Harbor Laboratory Therapeutic uses for nitric oxide inhibitors
US6372796B1 (en) 1996-11-13 2002-04-16 Cold Spring Harbor Laboratory Therapeutic uses for nitric oxide inhibitors
ATE336240T1 (de) 1996-11-13 2006-09-15 Cold Spring Harbor Lab Therapeutische verwendung von stickstoffmonoxydinhibitoren
AU8647198A (en) * 1997-08-12 1999-03-01 Chugai Seiyaku Kabushiki Kaisha Remedies for diseases associated with bone resorption
WO2000057891A1 (en) 1999-03-30 2000-10-05 Trustees Of Boston University Compositions and methods for producing platelets and/or proplatelets from megakaryocytes
CA2374209A1 (en) * 1999-05-20 2000-11-30 Cold Spring Harbor Laboratory Therapeutic uses for nitric oxide inhibitors
WO2003078578A2 (en) * 2002-03-12 2003-09-25 Lsu Medical Center Modulation of the immune response through the manipulation of arginine levels
WO2008034929A1 (es) * 2006-09-19 2008-03-27 Fundación Progreso Y Salud Método para el cultivo y mantenimiento de células troncales pluripotenciales y de células progenitoras de mamífero en estado no diferenciado
WO2010019905A1 (en) 2008-08-15 2010-02-18 N30 Pharmaceuticals, Llc Novel pyrrole inhibitors of s-nitrosoglutathione reductase as therapeutic agents
DK2315590T3 (da) 2008-08-15 2012-11-19 N30 Pharmaceuticals Inc Pyrrolinhibitorer af S-nitrosoglutathionreduktase
LT2318006T (lt) 2008-08-15 2017-01-10 Nivalis Therapeutics, Inc. Nauji s-nitrozoglutationo reduktazės pirolo inhibitoriai, kaip terapiniai agentai
US10745467B2 (en) 2010-03-26 2020-08-18 The Trustees Of Dartmouth College VISTA-Ig for treatment of autoimmune, allergic and inflammatory disorders
EP2552947A4 (de) 2010-03-26 2013-11-13 Dartmouth College Vista-regulatorisches t-zellen-mediator-protein, vista-bindende wirkstoffe und verwendung davon
US20150231215A1 (en) 2012-06-22 2015-08-20 Randolph J. Noelle VISTA Antagonist and Methods of Use
WO2012048275A2 (en) 2010-10-08 2012-04-12 Caridianbct, Inc. Configurable methods and systems of growing and harvesting cells in a hollow fiber bioreactor system
WO2013006635A1 (en) * 2011-07-05 2013-01-10 N30 Pharmaceuticals, Llc Novel pyrrole inhibitors of s-nitrosoglutathione reductase as therapeutic agents for liver toxicity
US9890215B2 (en) 2012-06-22 2018-02-13 King's College London Vista modulators for diagnosis and treatment of cancer
EP2892558B1 (de) 2012-09-07 2019-04-10 The Trustees Of Dartmouth College Vista-modulatoren zur diagnose und behandlung von krebs
CN105793411B (zh) 2013-11-16 2018-04-17 泰尔茂比司特公司 生物反应器中的细胞扩增
US11014987B2 (en) 2013-12-24 2021-05-25 Janssen Pharmaceutics Nv Anti-vista antibodies and fragments, uses thereof, and methods of identifying same
ES2920677T3 (es) 2013-12-24 2022-08-08 Janssen Pharmaceutica Nv Anticuerpos y fragmentos anti-VISTA
EP3613841B1 (de) 2014-03-25 2022-04-20 Terumo BCT, Inc. Passives ersetzen von medien
EP3154585B1 (de) 2014-06-11 2022-02-23 Kathy A. Green Verwendung von vista-agonisten und antagonisten zur unterdrückung oder verbesserung der humoralen immunität
US20160090569A1 (en) 2014-09-26 2016-03-31 Terumo Bct, Inc. Scheduled Feed
AU2015357463B2 (en) 2014-12-05 2021-10-07 Immunext, Inc. Identification of VSIG8 as the putative vista receptor and its use thereof to produce vista/VSIG8 modulators
CN107922497B (zh) 2015-06-24 2022-04-12 詹森药业有限公司 抗vista抗体和片段
WO2017004592A1 (en) 2015-07-02 2017-01-05 Terumo Bct, Inc. Cell growth with mechanical stimuli
TWI756204B (zh) 2016-02-12 2022-03-01 比利時商楊森製藥公司 抗ｖｉｓｔａ抗體及片段、其用途及鑑定其之方法
CN118108843A (zh) 2016-04-15 2024-05-31 伊穆奈克斯特股份有限公司 抗人vista抗体及其用途
EP3464565A4 (de) 2016-05-25 2020-01-01 Terumo BCT, Inc. Zellexpansion
US11104874B2 (en) 2016-06-07 2021-08-31 Terumo Bct, Inc. Coating a bioreactor
US11685883B2 (en) 2016-06-07 2023-06-27 Terumo Bct, Inc. Methods and systems for coating a cell growth surface
JP7393945B2 (ja) 2017-03-31 2023-12-07 テルモ ビーシーティー、インコーポレーテッド 細胞増殖
US11624046B2 (en) 2017-03-31 2023-04-11 Terumo Bct, Inc. Cell expansion

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1994028013A1 (en) * 1993-05-20 1994-12-08 Research Corporation Technologies, Inc. Peptides for suppression of myeloid progenitor cell proliferation and treatment of septic shock
JPH07316023A (ja) * 1994-05-26 1995-12-05 Shiseido Co Ltd 育毛料
ATE336240T1 (de) 1996-11-13 2006-09-15 Cold Spring Harbor Lab Therapeutische verwendung von stickstoffmonoxydinhibitoren

Also Published As

Publication number Publication date
DE69736526T2 (de) 2007-04-26
WO1998020865A2 (en) 1998-05-22
CA2271729A1 (en) 1998-05-22
EP0952828B1 (de) 2006-08-16
EP0952828A2 (de) 1999-11-03
AU5585598A (en) 1998-06-03
WO1998020865A3 (en) 1998-07-23
DE69736526D1 (de) 2006-09-28
US5977181A (en) 1999-11-02
US20030119905A1 (en) 2003-06-26
US6809117B2 (en) 2004-10-26

Similar Documents

Publication Publication Date Title
ATE336240T1 (de) Therapeutische verwendung von stickstoffmonoxydinhibitoren
DE69721006D1 (de) Verwendung des modifizierten eigenen blutes zur behandlung von autoimmunerkrankungen
ATE212237T1 (de) Verwendung von neuronalen fötalen zellinien für transplantationstherapie
ES551761A0 (es) Un procedimiento para la preparacion de un vector de dna recombinante
ATE219519T1 (de) Rekombinanttherapien für infektionen und hyperproliferative störungen
HUP0103578A2 (hu) Az oszteoprotegerin-ligand aktivitásának csökkentő szabályozására szolgáló eljárás
ATE258796T1 (de) Verwendung von vitamin d4-derivaten zur behandlung von hauterkrankungen
SE8902532D0 (sv) Bestaemning av plasmaproteiner
DE69518760D1 (de) Wachstumsdifferenzierungsfaktor-12
EA200001124A1 (ru) Способ генной терапии
HUP9901188A2 (hu) Új, meghatározott enzimkeverékek sejtkinyeréshez és sebkezeléshez
DE69633393D1 (de) Mitteln zur behandlung von auto-immun krankheiten
ATE499445T1 (de) Menschliche ubiqutin ligase e3. verwendung für die modulation von nf-kappa b
Liu et al. Dupuytren's disease among the Chinese in Taiwan
DE69824017D1 (de) Vehikel zur gentherapie enthaltend dermales huellgewebe
DE69332373D1 (de) Menschlicher epidermaler Gen-Promotor
MacLennan et al. Scalp autografts and hair transfer to the face in the burned child
DE69528473D1 (de) Verwendung von hepatozyten-wachstumsfaktor zur induzierung der proliferation und differenzierung von hämatopoietischen zellen
PT990000E (pt) Factor 3 de crescimento do tecido conjuntivo
DE50004024D1 (de) Verwendung von treosulfan zur konditionierung von patienten vor knochenmarktransplantation oder blutstammzelltransplantation
SU628904A1 (ru) Способ обезболивани
WO1995035373A3 (en) Nucleic acid molecules encoding human contactin
Steinmann et al. Collagen disorders
Kohutis Risk-taking, life satisfaction, and locus of control in older adults.
UA6493A (uk) Хірургічний скальпель

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties