ATE334137T1 - Ringerweiterte nukleoside und nukleotide - Google Patents

Ringerweiterte nukleoside und nukleotide

Info

Publication number
ATE334137T1
ATE334137T1 AT02001587T AT02001587T ATE334137T1 AT E334137 T1 ATE334137 T1 AT E334137T1 AT 02001587 T AT02001587 T AT 02001587T AT 02001587 T AT02001587 T AT 02001587T AT E334137 T1 ATE334137 T1 AT E334137T1
Authority
AT
Austria
Prior art keywords
compositions
nucleosides
ringer
nucleotides
extended
Prior art date
Application number
AT02001587T
Other languages
English (en)
Inventor
Barry Burns
Ramachandra Hosmane
Original Assignee
Nabi
Univ Maryland
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nabi, Univ Maryland filed Critical Nabi
Application granted granted Critical
Publication of ATE334137T1 publication Critical patent/ATE334137T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/052—Imidazole radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Genetics & Genomics (AREA)
  • Communicable Diseases (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Oncology (AREA)
  • Molecular Biology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
AT02001587T 1993-09-29 1994-09-29 Ringerweiterte nukleoside und nukleotide ATE334137T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US12821293A 1993-09-29 1993-09-29

Publications (1)

Publication Number Publication Date
ATE334137T1 true ATE334137T1 (de) 2006-08-15

Family

ID=22434211

Family Applications (2)

Application Number Title Priority Date Filing Date
AT94929358T ATE223428T1 (de) 1993-09-29 1994-09-29 Nukleoside und nukleotide mit vergrösserten ringen
AT02001587T ATE334137T1 (de) 1993-09-29 1994-09-29 Ringerweiterte nukleoside und nukleotide

Family Applications Before (1)

Application Number Title Priority Date Filing Date
AT94929358T ATE223428T1 (de) 1993-09-29 1994-09-29 Nukleoside und nukleotide mit vergrösserten ringen

Country Status (9)

Country Link
EP (2) EP1227103B1 (de)
AT (2) ATE223428T1 (de)
AU (1) AU7844594A (de)
CA (1) CA2173116C (de)
DE (2) DE69431304T2 (de)
DK (2) DK0724587T3 (de)
ES (2) ES2269528T3 (de)
PT (2) PT1227103E (de)
WO (1) WO1995009175A1 (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7094766B1 (en) 1995-06-06 2006-08-22 Trustees Of Boston University Use of locally applied DNA fragments
US20030032610A1 (en) 1996-06-03 2003-02-13 Gilchrest Barbara A. Method to inhibit cell growth using oligonucleotides
US6147056A (en) * 1995-06-06 2000-11-14 Trustees Of Boston University Use of locally applied DNA fragments
US5955059A (en) * 1995-06-06 1999-09-21 Trustees Of Boston University Use of locally applied DNA fragments
EP1274410A2 (de) 2000-03-31 2003-01-15 Trustees Of Boston University Verwendung von lokal aplizierten dna-fragmenten
US6555581B1 (en) 2001-02-15 2003-04-29 Jones Pharma, Inc. Levothyroxine compositions and methods
FR2825705B1 (fr) 2001-06-08 2005-05-20 Aventis Pharma Sa Nouveaux composes heterocycliques, leur preparation et leur utilisation comme medicaments, notamment comme anti-bacteriens
FR2835186B1 (fr) 2002-01-28 2006-10-20 Aventis Pharma Sa Nouveaux composes heterocycliques, actifs comme inhibiteurs de beta-lactamases
FR2844273B1 (fr) 2002-09-05 2008-04-04 Aventis Pharma Sa Nouveaux composes heterocycliques, procede et intermediaires de preparation et utilisation comme medicament, notamment comme inhibiteurs de beta-lactamases et anti-bacteriens.
CN107074904B (zh) 2014-10-23 2022-12-23 深圳华大智造科技股份有限公司 信号约束测序(scs)和用于信号约束测序的核苷酸类似物

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS60992B2 (ja) * 1977-03-15 1985-01-11 財団法人微生物化学研究会 コホルマイシンおよび関連物質の分離法
US4163839A (en) * 1977-12-09 1979-08-07 Zaidan Hojin Biselbutsu Kagaku Kenkyu Kai Isocoformycin and a process for the production thereof
US4935505A (en) * 1983-05-03 1990-06-19 Townsend Leroy B Novel azolo [1,3] diazepine-5-ol compounds and their uses
US4713372A (en) * 1984-03-16 1987-12-15 Warner-Lambert Company 2-chloropentostatin compound having adenosine diaminase inhibitory activity
IL108524A0 (en) * 1993-02-03 1994-05-30 Gensia Inc Imidazodiazepine analogs

Also Published As

Publication number Publication date
DK0724587T3 (da) 2003-01-06
DE69434805T2 (de) 2007-02-22
CA2173116C (en) 2006-02-28
DE69431304D1 (de) 2002-10-10
WO1995009175A1 (en) 1995-04-06
DE69434805D1 (de) 2006-09-07
PT724587E (pt) 2003-01-31
DK1227103T3 (da) 2006-11-27
PT1227103E (pt) 2006-12-29
AU7844594A (en) 1995-04-18
ES2269528T3 (es) 2007-04-01
ES2182847T3 (es) 2003-03-16
EP1227103A3 (de) 2002-10-16
EP0724587A1 (de) 1996-08-07
EP0724587B1 (de) 2002-09-04
DE69431304T2 (de) 2003-05-15
EP1227103B1 (de) 2006-07-26
EP0724587A4 (de) 1996-12-27
ATE223428T1 (de) 2002-09-15
EP0724587B8 (de) 2003-01-29
CA2173116A1 (en) 1995-04-06
EP1227103A2 (de) 2002-07-31

Similar Documents

Publication Publication Date Title
IL101836A0 (en) Pharmaceutical compositions containing 1,3-oxathiolane nucleoside derivatives
MD1224B2 (en) Application of nucleoside analogues with 1,3-oxathiolan for treatment of hepatitis B
MY109796A (en) 1,3-oxathiolane nucleoside analogues.
TW366347B (en) Antiviral pharmaceutical compositions comprising 1,3-oxathiolane nucleoside analogues
IL101144A0 (en) Pharmaceutical compositions containing 1,3-oxathiolane nucleoside analogue and derivatives thereof for the treatment of hepatitis b virus infections
RU93043875A (ru) 1-(2-гидроксиметил)-1,3-оксатиолан-5-ил)-5-фторцитозин и способ лечения
MD1838G2 (ro) Derivaţi de 5,6-diclorbenzimidazol, procedeu de obţinere a lor, compoziţie farmaceutică şi metodă de tratament sau de prevenire a infecţiei virotice herpetice
WO2004046159A8 (en) Antiviral nucleoside derivatives
ES2138969T3 (es) Combinacion de nucleosidos antivirales.
MY127808A (en) Use of dideoxy nucleoside analogues in the treatment of viral infections
ATE334137T1 (de) Ringerweiterte nukleoside und nukleotide
MY105523A (en) Substituted-1,3-oxathiolanes with antiviral properties.
IE893991L (en) 2',3'-dideoxypurine nucleoside/purine nucleoside¹phosphorylase inhibitor combination therapy and composition
IE893080L (en) Novel 2'-halomethylidene,2'-ethenylidene and¹2'-ethynyl adenosine derivatives
MX9701273A (es) Succinato de (4-(2-amino-6-(ciclopropilamino)-9h-purin-9-il)2-ciclopenten-1-metanol como agente antiviral.
MY137298A (en) Therapeutic nucleosides
IL92402A0 (en) Pyrimidine nucleoside derivatives,their preparation and pharmaceutical compositions containing them
ES2078380T3 (es) Oligofosfatos de accion antiviral.
MY103900A (en) 6-substituted 2'', 3''-dideoxynucleosides and pharmaceutical compositions
MY113560A (en) Use of 5-fluoro-2'-deoxy-3'-thiacytidine for the treatment of hepatitis b
ES2067395A1 (es) Derivados de nucleosidos o analogos a nucleosidos.

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification

Ref document number: 1227103

Country of ref document: EP

REN Ceased due to non-payment of the annual fee