DE69431304D1 - Nukleoside und nukleotide mit vergrösserten ringen - Google Patents

Nukleoside und nukleotide mit vergrösserten ringen

Info

Publication number
DE69431304D1
DE69431304D1 DE69431304T DE69431304T DE69431304D1 DE 69431304 D1 DE69431304 D1 DE 69431304D1 DE 69431304 T DE69431304 T DE 69431304T DE 69431304 T DE69431304 T DE 69431304T DE 69431304 D1 DE69431304 D1 DE 69431304D1
Authority
DE
Germany
Prior art keywords
compositions
nucleosides
nucleotides
purine
ring
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69431304T
Other languages
English (en)
Other versions
DE69431304T2 (de
Inventor
Barry Burns
Ramachandra Hosmane
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Maryland at Baltimore
University of Maryland at Baltimore County UMBC
Original Assignee
University of Maryland at Baltimore
University of Maryland at Baltimore County UMBC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of Maryland at Baltimore, University of Maryland at Baltimore County UMBC filed Critical University of Maryland at Baltimore
Application granted granted Critical
Publication of DE69431304D1 publication Critical patent/DE69431304D1/de
Publication of DE69431304T2 publication Critical patent/DE69431304T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/052—Imidazole radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
DE69431304T 1993-09-29 1994-09-29 Nukleoside und nukleotide mit vergrösserten ringen Expired - Lifetime DE69431304T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US12821293A 1993-09-29 1993-09-29
PCT/US1994/010905 WO1995009175A1 (en) 1993-09-29 1994-09-29 Ring-expanded nucleosides and nucleotides

Publications (2)

Publication Number Publication Date
DE69431304D1 true DE69431304D1 (de) 2002-10-10
DE69431304T2 DE69431304T2 (de) 2003-05-15

Family

ID=22434211

Family Applications (2)

Application Number Title Priority Date Filing Date
DE69431304T Expired - Lifetime DE69431304T2 (de) 1993-09-29 1994-09-29 Nukleoside und nukleotide mit vergrösserten ringen
DE69434805T Expired - Lifetime DE69434805T2 (de) 1993-09-29 1994-09-29 Ringerweiterte Nukleoside und Nukleotide

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE69434805T Expired - Lifetime DE69434805T2 (de) 1993-09-29 1994-09-29 Ringerweiterte Nukleoside und Nukleotide

Country Status (9)

Country Link
EP (2) EP0724587B8 (de)
AT (2) ATE334137T1 (de)
AU (1) AU7844594A (de)
CA (1) CA2173116C (de)
DE (2) DE69431304T2 (de)
DK (2) DK1227103T3 (de)
ES (2) ES2182847T3 (de)
PT (2) PT724587E (de)
WO (1) WO1995009175A1 (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7094766B1 (en) 1995-06-06 2006-08-22 Trustees Of Boston University Use of locally applied DNA fragments
US5955059A (en) * 1995-06-06 1999-09-21 Trustees Of Boston University Use of locally applied DNA fragments
US6147056A (en) * 1995-06-06 2000-11-14 Trustees Of Boston University Use of locally applied DNA fragments
US20030032610A1 (en) 1996-06-03 2003-02-13 Gilchrest Barbara A. Method to inhibit cell growth using oligonucleotides
AU2001251115A1 (en) 2000-03-31 2001-10-15 Trustees Of Boston University Use of locally applied dna fragments
US6555581B1 (en) 2001-02-15 2003-04-29 Jones Pharma, Inc. Levothyroxine compositions and methods
FR2825705B1 (fr) 2001-06-08 2005-05-20 Aventis Pharma Sa Nouveaux composes heterocycliques, leur preparation et leur utilisation comme medicaments, notamment comme anti-bacteriens
FR2835186B1 (fr) 2002-01-28 2006-10-20 Aventis Pharma Sa Nouveaux composes heterocycliques, actifs comme inhibiteurs de beta-lactamases
FR2844273B1 (fr) 2002-09-05 2008-04-04 Aventis Pharma Sa Nouveaux composes heterocycliques, procede et intermediaires de preparation et utilisation comme medicament, notamment comme inhibiteurs de beta-lactamases et anti-bacteriens.
US10190162B2 (en) 2014-10-23 2019-01-29 Complete Genomics, Inc. Signal confinement sequencing (SCS) and nucleotide analogues for signal confinement sequencing

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS60992B2 (ja) * 1977-03-15 1985-01-11 財団法人微生物化学研究会 コホルマイシンおよび関連物質の分離法
US4163839A (en) * 1977-12-09 1979-08-07 Zaidan Hojin Biselbutsu Kagaku Kenkyu Kai Isocoformycin and a process for the production thereof
US4935505A (en) * 1983-05-03 1990-06-19 Townsend Leroy B Novel azolo [1,3] diazepine-5-ol compounds and their uses
US4713372A (en) * 1984-03-16 1987-12-15 Warner-Lambert Company 2-chloropentostatin compound having adenosine diaminase inhibitory activity
IL108524A0 (en) * 1993-02-03 1994-05-30 Gensia Inc Imidazodiazepine analogs

Also Published As

Publication number Publication date
ATE334137T1 (de) 2006-08-15
ES2182847T3 (es) 2003-03-16
DE69434805D1 (de) 2006-09-07
DE69431304T2 (de) 2003-05-15
DK1227103T3 (da) 2006-11-27
EP0724587A4 (de) 1996-12-27
CA2173116C (en) 2006-02-28
DK0724587T3 (da) 2003-01-06
EP0724587B8 (de) 2003-01-29
EP1227103A3 (de) 2002-10-16
EP1227103B1 (de) 2006-07-26
EP0724587A1 (de) 1996-08-07
WO1995009175A1 (en) 1995-04-06
DE69434805T2 (de) 2007-02-22
AU7844594A (en) 1995-04-18
EP1227103A2 (de) 2002-07-31
PT1227103E (pt) 2006-12-29
ATE223428T1 (de) 2002-09-15
PT724587E (pt) 2003-01-31
EP0724587B1 (de) 2002-09-04
ES2269528T3 (es) 2007-04-01
CA2173116A1 (en) 1995-04-06

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition