ATE328893T1 - Antibakterielle protonierte oligonukleotide - Google Patents
Antibakterielle protonierte oligonukleotideInfo
- Publication number
- ATE328893T1 ATE328893T1 AT99966301T AT99966301T ATE328893T1 AT E328893 T1 ATE328893 T1 AT E328893T1 AT 99966301 T AT99966301 T AT 99966301T AT 99966301 T AT99966301 T AT 99966301T AT E328893 T1 ATE328893 T1 AT E328893T1
- Authority
- AT
- Austria
- Prior art keywords
- protonated
- oligonucleotides
- antibacterial
- nucleic acids
- resistant
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N57/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic phosphorus compounds
- A01N57/10—Biocides, pest repellants or attractants, or plant growth regulators containing organic phosphorus compounds having phosphorus-to-oxygen bonds or phosphorus-to-sulfur bonds
- A01N57/16—Biocides, pest repellants or attractants, or plant growth regulators containing organic phosphorus compounds having phosphorus-to-oxygen bonds or phosphorus-to-sulfur bonds containing heterocyclic radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/60—Sugars; Derivatives thereof
- A61K8/606—Nucleosides; Nucleotides; Nucleic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/02—Local antiseptics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
- C07H21/02—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids with ribosyl as saccharide radical
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Molecular Biology (AREA)
- Veterinary Medicine (AREA)
- Biochemistry (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Plant Pathology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Communicable Diseases (AREA)
- Dermatology (AREA)
- Birds (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Agronomy & Crop Science (AREA)
- Pest Control & Pesticides (AREA)
- Oncology (AREA)
- Dentistry (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Environmental Sciences (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Saccharide Compounds (AREA)
- Medicinal Preparation (AREA)
- Cosmetics (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US09/222,009 US6211349B1 (en) | 1998-12-30 | 1998-12-30 | Protonated/acidified nucleic acids and methods of use |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE328893T1 true ATE328893T1 (de) | 2006-06-15 |
Family
ID=22830357
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT99966301T ATE328893T1 (de) | 1998-12-30 | 1999-12-15 | Antibakterielle protonierte oligonukleotide |
Country Status (8)
Country | Link |
---|---|
US (1) | US6211349B1 (de) |
EP (1) | EP1140965B1 (de) |
JP (1) | JP2002534433A (de) |
AT (1) | ATE328893T1 (de) |
AU (1) | AU2187300A (de) |
CA (1) | CA2358570C (de) |
DE (1) | DE69931809T2 (de) |
WO (1) | WO2000040591A1 (de) |
Families Citing this family (24)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5855911A (en) * | 1995-08-29 | 1999-01-05 | Board Of Regents, The University Of Texas System | Liposomal phosphodiester, phosphorothioate, and P-ethoxy oligonucleotides |
US7309692B1 (en) | 1996-07-08 | 2007-12-18 | Board Of Regents, The University Of Texas System | Inhibition of chronic myelogenous leukemic cell growth by liposomal-antisense oligodeoxy-nucleotides targeting to GRB2 or CRK1 |
US6977244B2 (en) | 1996-10-04 | 2005-12-20 | Board Of Regents, The University Of Texas Systems | Inhibition of Bcl-2 protein expression by liposomal antisense oligodeoxynucleotides |
US7704962B1 (en) | 1997-10-03 | 2010-04-27 | Board Of Regents, The University Of Texas System | Small oligonucleotides with anti-tumor activity |
US7285288B1 (en) | 1997-10-03 | 2007-10-23 | Board Of Regents, The University Of Texas System | Inhibition of Bcl-2 protein expression by liposomal antisense oligodeoxynucleotides |
US6211162B1 (en) * | 1998-12-30 | 2001-04-03 | Oligos Etc. Inc. | Pulmonary delivery of protonated/acidified nucleic acids |
US20020032164A1 (en) | 1998-12-30 | 2002-03-14 | Dale Roderic M. K. | Antimicrobial compounds and methods for their use |
US6627215B1 (en) * | 1998-12-30 | 2003-09-30 | Oligos Etc. Inc. | Devices for improved wound management |
US7868162B2 (en) * | 1998-12-30 | 2011-01-11 | Lakewood-Amedex, Inc. | Antimicrobial and antiviral compounds and methods for their use |
US20050136458A1 (en) * | 1998-12-31 | 2005-06-23 | Oligos, Etc, Inc. | Method for nucleic acid preparation |
AU2002327180A1 (en) * | 2001-06-04 | 2003-01-21 | The General Hospital Corporation | Detection and therapy of vulnerable plaque with photodynamic compounds |
JP3602071B2 (ja) * | 2001-06-05 | 2004-12-15 | 株式会社日立製作所 | 核酸の精製分離方法 |
IL159722A0 (en) * | 2001-07-10 | 2004-06-20 | Oligos Etc Inc | Pharmaceutical compositions containing oligonucleotides |
WO2003061386A1 (en) * | 2002-01-03 | 2003-07-31 | Board Of Regents, The University Of Texas System | Wt1 antisense oligos for the inhibition of breast cancer |
AU2004269150C1 (en) * | 2003-08-28 | 2010-11-18 | Novartis Ag | Interfering RNA duplex having blunt-ends and 3'-modifications |
WO2006122409A1 (en) * | 2005-05-16 | 2006-11-23 | Replicor Inc. | Antimicrobial molecules and their uses |
WO2007022642A2 (en) * | 2005-08-25 | 2007-03-01 | Replicor Inc. | Anti-inflammatory molecules and their uses |
GB0608838D0 (en) | 2006-05-04 | 2006-06-14 | Novartis Ag | Organic compounds |
US11377468B2 (en) | 2017-03-10 | 2022-07-05 | Lakewood Amedex, Inc. | Antimicrobial compounds, compositions, and uses thereof |
US12030908B2 (en) | 2017-03-10 | 2024-07-09 | Lakewood Amedex, Inc. | Antimicrobial compounds, compositions, and uses thereof |
US11795192B2 (en) | 2017-03-10 | 2023-10-24 | Lakewood Amedex, Inc. | Antimicrobial compounds, compositions, and uses thereof |
CN110612143B (zh) * | 2017-03-10 | 2021-07-02 | 莱克伍德阿美达克斯股份有限公司 | 抗微生物化合物、组合物及其用途 |
CA3066722A1 (en) | 2017-06-12 | 2018-12-20 | Lakewood Amedex, Inc | Bisphosphocin gel formulations and uses thereof |
KR20210075968A (ko) | 2018-10-17 | 2021-06-23 | 레이크우드 아메덱스, 인크. | 구강 점막염을 치료하기 위한 방법 및 조성물 |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5115637A (en) * | 1974-07-26 | 1976-02-07 | Yukio Kobayashi | Ch3 cooh to pentakurorufuenoorunokongonyoru satsukinseibutsushitsu |
CA1231053A (en) * | 1984-01-09 | 1988-01-05 | Capetrol International, Inc. | Germicides having ph values of less than about l |
US5294533A (en) | 1988-07-05 | 1994-03-15 | Baylor College Of Medicine | Antisense oligonucleotide antibiotics complementary to the macromolecular synthesis operon, methods of treating bacterial infections and methods for identification of bacteria |
ZA902710B (en) * | 1989-05-22 | 1991-12-24 | Univ Georgia Res Found | Enzyme luminescence assay |
IL108206A0 (en) * | 1993-01-06 | 1994-04-12 | Univ Johns Hopkins | Oligomers having improved stability at acid ph |
GB9505438D0 (en) | 1995-03-17 | 1995-05-03 | Sod Conseils Rech Applic | Antisense oligonucleotides |
US5747256A (en) * | 1995-12-19 | 1998-05-05 | Beckman Instruments, Inc. | Homogeneous DNA probe titration assay |
WO1998003533A1 (en) * | 1996-07-24 | 1998-01-29 | Oligos Etc. And Oligos Therapeutics, Inc. | Antisense oligonucleotides as antibacterial agents |
-
1998
- 1998-12-30 US US09/222,009 patent/US6211349B1/en not_active Expired - Lifetime
-
1999
- 1999-12-15 WO PCT/US1999/029843 patent/WO2000040591A1/en active IP Right Grant
- 1999-12-15 DE DE69931809T patent/DE69931809T2/de not_active Expired - Lifetime
- 1999-12-15 AU AU21873/00A patent/AU2187300A/en not_active Abandoned
- 1999-12-15 EP EP99966301A patent/EP1140965B1/de not_active Expired - Lifetime
- 1999-12-15 AT AT99966301T patent/ATE328893T1/de not_active IP Right Cessation
- 1999-12-15 JP JP2000592299A patent/JP2002534433A/ja active Pending
- 1999-12-15 CA CA2358570A patent/CA2358570C/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
EP1140965A1 (de) | 2001-10-10 |
WO2000040591A1 (en) | 2000-07-13 |
EP1140965B1 (de) | 2006-06-07 |
AU2187300A (en) | 2000-07-24 |
DE69931809D1 (de) | 2006-07-20 |
CA2358570A1 (en) | 2000-07-13 |
DE69931809T2 (de) | 2007-01-04 |
CA2358570C (en) | 2013-02-26 |
JP2002534433A (ja) | 2002-10-15 |
US6211349B1 (en) | 2001-04-03 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |