ATE324901T1 - Hemmung der angiogenese durch peptidanaloge der kininogen domäne 5mit hohem molekulargewicht - Google Patents

Hemmung der angiogenese durch peptidanaloge der kininogen domäne 5mit hohem molekulargewicht

Info

Publication number
ATE324901T1
ATE324901T1 AT99957529T AT99957529T ATE324901T1 AT E324901 T1 ATE324901 T1 AT E324901T1 AT 99957529 T AT99957529 T AT 99957529T AT 99957529 T AT99957529 T AT 99957529T AT E324901 T1 ATE324901 T1 AT E324901T1
Authority
AT
Austria
Prior art keywords
angiogenesis
molecular weight
high molecular
inhibition
peptide analogues
Prior art date
Application number
AT99957529T
Other languages
English (en)
Inventor
W Robert Colman
A Shaker Mousa
Original Assignee
Univ Temple
Du Pont Pharm Co
W Robert Colman
A Shaker Mousa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Temple, Du Pont Pharm Co, W Robert Colman, A Shaker Mousa filed Critical Univ Temple
Application granted granted Critical
Publication of ATE324901T1 publication Critical patent/ATE324901T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/81—Protease inhibitors
    • C07K14/8107—Endopeptidase (E.C. 3.4.21-99) inhibitors
    • C07K14/8139—Cysteine protease (E.C. 3.4.22) inhibitors, e.g. cystatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
AT99957529T 1998-11-10 1999-11-09 Hemmung der angiogenese durch peptidanaloge der kininogen domäne 5mit hohem molekulargewicht ATE324901T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US10784498P 1998-11-10 1998-11-10

Publications (1)

Publication Number Publication Date
ATE324901T1 true ATE324901T1 (de) 2006-06-15

Family

ID=22318781

Family Applications (1)

Application Number Title Priority Date Filing Date
AT99957529T ATE324901T1 (de) 1998-11-10 1999-11-09 Hemmung der angiogenese durch peptidanaloge der kininogen domäne 5mit hohem molekulargewicht

Country Status (6)

Country Link
US (1) US6284726B1 (de)
EP (1) EP1044012B1 (de)
AT (1) ATE324901T1 (de)
AU (1) AU1521500A (de)
DE (1) DE69931140T2 (de)
WO (1) WO2000027415A2 (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6767889B1 (en) * 1998-11-10 2004-07-27 Temple University Of The Commonwealth System Of Higher Education Inhibition of angiogenesis by high molecular weight kininogen and peptide analogs thereof
US6821947B2 (en) * 2001-12-04 2004-11-23 Thomas Jefferson University Endorepellin: methods and compositions for inhibiting angiogenesis
EP1344531A1 (de) * 2002-03-15 2003-09-17 Aventis Behring GmbH Peptide abgeleitet von der Domäne 5 von Kininogen von hohem Molekulargewicht (HK) gegen thrombische Krankheiten
AU2003267199A1 (en) * 2002-09-13 2004-04-30 Attenuon, Llc Human kininogen d3 domain polypeptide as an anti-angiogenic and anti-tumor agent
SE0301431D0 (sv) 2003-05-19 2003-05-19 Dermagen Novel antimicrobial peptides
US8440217B1 (en) 2005-06-15 2013-05-14 Mawaheb M. EL-Naggar Method and system with contact lens product for treating and preventing adverse eye conditions
US8883153B2 (en) * 2009-03-27 2014-11-11 The Research for The State University of New York Methods for preventing and treating angioedema
CO2018007216A2 (es) 2015-12-15 2018-09-20 Dyax Corp Ensayo de cuantificacion de peptido para diferenciar quininogeno de alto peso molecular (hmwk) de longitud completa y hmwk escindido
EP3562499A1 (de) * 2016-12-29 2019-11-06 Development Center for Biotechnology Aus kininogen-1 abgeleitete peptide für proteinarzneimittel in vivo

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5580722A (en) * 1989-07-18 1996-12-03 Oncogene Science, Inc. Methods of determining chemicals that modulate transcriptionally expression of genes associated with cardiovascular disease
US5596079A (en) 1991-12-16 1997-01-21 Smith; James R. Mimetics of senescent cell derived inhibitors of DNA synthesis
US5756291A (en) 1992-08-21 1998-05-26 Gilead Sciences, Inc. Aptamers specific for biomolecules and methods of making
JPH0782172A (ja) * 1993-09-17 1995-03-28 Hoechst Japan Ltd 創傷治療剤
CA2189340A1 (en) 1994-05-04 1995-11-16 James W. Dennis Modulators of cytokines of the tgf-.beta. superfamily and methods for assaying for same
JPH08208692A (ja) 1994-09-28 1996-08-13 Sumitomo Pharmaceut Co Ltd 新規な細胞接着抑制ペプチド誘導体
MX9703988A (es) * 1994-12-12 1998-02-28 Omeros Med Sys Inc SOLUCIaN Y MÉTODO DE IRRIGACIaN PARA LA INHIBICIaN DEL DOLOR, LA INFLAMACIaN Y ES ESPASMO.
US5817748A (en) 1995-03-17 1998-10-06 The Research Foundation Of State University Of New York Mimotopes of human Platelet glycoprotein Ib/IX
EP0871464B1 (de) 1995-06-09 2003-04-02 The Regents Of The University Of Michigan Bradikininanaloge als selektive thrombininhibitoren
EP0808627A2 (de) 1996-05-22 1997-11-26 Hoechst Aktiengesellschaft Verwendung nicht-peptidischer Bradykinin-Antagonisten zur Behandlung und Prävention von chronisch-fibrogenetischen Lebererkrankungen, akuten Lebererkrankungen und den damit verbundenen Komplikationen
CA2187728A1 (en) 1996-05-29 1997-11-29 Mary Lou Guerinot Iron-regulated metal transporters and uses therefor

Also Published As

Publication number Publication date
EP1044012A4 (de) 2003-07-09
US6284726B1 (en) 2001-09-04
DE69931140D1 (de) 2006-06-08
EP1044012A1 (de) 2000-10-18
DE69931140T2 (de) 2007-02-01
AU1521500A (en) 2000-05-29
WO2000027415A2 (en) 2000-05-18
EP1044012B1 (de) 2006-05-03

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