ATE324373T1 - Immunmodulierende verbindungen - Google Patents

Immunmodulierende verbindungen

Info

Publication number
ATE324373T1
ATE324373T1 AT02746260T AT02746260T ATE324373T1 AT E324373 T1 ATE324373 T1 AT E324373T1 AT 02746260 T AT02746260 T AT 02746260T AT 02746260 T AT02746260 T AT 02746260T AT E324373 T1 ATE324373 T1 AT E324373T1
Authority
AT
Austria
Prior art keywords
compound
relates
present
novel heterocyclic
immunomodulating compounds
Prior art date
Application number
AT02746260T
Other languages
English (en)
Inventor
Per Axel Bjoerk
Tomas Fex
Lars Olof Goeran Pettersson
Poul Sorensen
Graca Thrige Dorthe Da
Original Assignee
Active Biotech Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Active Biotech Ab filed Critical Active Biotech Ab
Application granted granted Critical
Publication of ATE324373T1 publication Critical patent/ATE324373T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Diabetes (AREA)
  • Rheumatology (AREA)
  • Pulmonology (AREA)
  • Emergency Medicine (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Obesity (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Endocrinology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Hematology (AREA)
  • Dermatology (AREA)
  • Transplantation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AT02746260T 2001-07-04 2002-07-02 Immunmodulierende verbindungen ATE324373T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE0102404A SE0102404D0 (sv) 2001-07-04 2001-07-04 Novel immunomodulating compounds

Publications (1)

Publication Number Publication Date
ATE324373T1 true ATE324373T1 (de) 2006-05-15

Family

ID=20284743

Family Applications (1)

Application Number Title Priority Date Filing Date
AT02746260T ATE324373T1 (de) 2001-07-04 2002-07-02 Immunmodulierende verbindungen

Country Status (21)

Country Link
EP (1) EP1409485B1 (de)
JP (1) JP2005501033A (de)
CN (1) CN1249063C (de)
AT (1) ATE324373T1 (de)
AU (1) AU2002315996B2 (de)
BR (1) BR0210776A (de)
CA (1) CA2451749A1 (de)
DE (1) DE60210977T2 (de)
ES (1) ES2258150T3 (de)
HK (1) HK1066809A1 (de)
HR (1) HRP20031055B1 (de)
HU (1) HUP0401204A3 (de)
MX (1) MXPA04000017A (de)
NO (1) NO20035684L (de)
NZ (1) NZ530316A (de)
PL (1) PL367637A1 (de)
RU (1) RU2004103079A (de)
SE (1) SE0102404D0 (de)
WO (1) WO2003004495A1 (de)
YU (1) YU101603A (de)
ZA (1) ZA200309806B (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1562944B1 (de) * 2002-11-22 2007-02-14 Active Biotech AB Pyrazolochinoline mit immunmodulierenderwirkung
ATE425164T1 (de) 2002-12-16 2009-03-15 Active Biotech Ab Tetrazyklische immunmodulierende verbindungen
GB0305876D0 (en) * 2003-03-14 2003-04-16 Avidex Ltd Immuno inhibitory heterocyclic compounds
EP2284172A1 (de) * 2003-03-14 2011-02-16 MediGene Ltd. Immunmodulierende heterocyclische Verbindungen
GB0325644D0 (en) 2003-11-04 2003-12-10 Avidex Ltd Immuno ihibitory pyrazolone compounds
CA2553329A1 (en) 2004-01-14 2005-07-28 Ajinomoto Co., Inc. New fused polycyclic compounds
GB0411770D0 (en) * 2004-05-26 2004-06-30 Avidex Ltd Immuno inhibitory heterocyclic compouds
DK1776366T3 (da) 2004-08-09 2009-02-16 Medigene Ltd Immunomodulerende oxopyrazolocinnoliner som CD80-inhibitorer
CN101863903B (zh) * 2010-06-08 2014-03-12 沈阳药科大学 1,4-二氢噻吩并[3’,2’:5,6]噻喃并[4,3-c]吡唑-3-羧酸衍生物及其应用
BR112015030387B1 (pt) * 2013-06-24 2021-02-09 Merck Patent Gmbh compostos de pirazol moduladores de fshr, seus usos, e composição farmacêutica
EP2883883A1 (de) 2013-12-16 2015-06-17 Cardio3 Biosciences S.A. Therapeutische Ziele und Mittel zur Behandlung von ischämiebedingten Reperfusionsschäden
NZ728298A (en) 2014-07-08 2017-09-29 Avertana Ltd Extraction of products from titanium-bearing minerals

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4268516A (en) * 1978-10-11 1981-05-19 Pfizer Inc. [1]Benzothiopyrano[4,3-c]pyrazoles as immunoregulatory agents
US4312870A (en) * 1979-06-21 1982-01-26 Ciba-Geigy Corporation Pyrazoloquinolines
GB8818895D0 (en) * 1988-08-09 1988-09-14 Boots Co Plc Therapeutic agents
PH26314A (en) * 1988-08-09 1994-04-29 Boots Co Plc Benzopyrano [4,3-c] pyrazoles derivatives
SE8903564D0 (sv) * 1989-10-26 1989-10-26 Pharmacia Ab New use condensed quinoline compound
BR9105984A (pt) * 1990-02-02 1992-11-10 Boots Co Plc Processo de preparacao de derivados do pirazol e de composicoes farmaceuticas que contem os mesmos
AR006520A1 (es) * 1996-03-20 1999-09-08 Astra Pharma Prod Derivados de 2-arilpirazolisoquinolina y cinolinona y procedimiento para su preparacion.

Also Published As

Publication number Publication date
HK1066809A1 (en) 2005-04-01
DE60210977T2 (de) 2006-09-21
NO20035684L (no) 2004-03-02
NO20035684D0 (no) 2003-12-19
EP1409485A1 (de) 2004-04-21
CN1249063C (zh) 2006-04-05
JP2005501033A (ja) 2005-01-13
MXPA04000017A (es) 2004-05-21
EP1409485B1 (de) 2006-04-26
YU101603A (en) 2006-05-25
ES2258150T3 (es) 2006-08-16
WO2003004495A1 (en) 2003-01-16
HUP0401204A2 (hu) 2004-10-28
ZA200309806B (en) 2004-12-20
BR0210776A (pt) 2004-07-20
NZ530316A (en) 2004-08-27
AU2002315996B2 (en) 2007-11-29
DE60210977D1 (de) 2006-06-01
HRP20031055B1 (en) 2008-01-31
CN1522254A (zh) 2004-08-18
HUP0401204A3 (en) 2008-03-28
CA2451749A1 (en) 2003-01-16
HRP20031055A2 (en) 2004-06-30
PL367637A1 (en) 2005-03-07
SE0102404D0 (sv) 2001-07-04
RU2004103079A (ru) 2005-06-10

Similar Documents

Publication Publication Date Title
HK1086562A1 (en) Pyrazoloquinolines with immunomodulating activity
HK1067120A1 (en) Glutaminyl based dpiv inhibitors
WO2005092895A3 (en) Alpha aryl or heteroaryl methyl beta piperidino propanoic acid compounds as orl1-receptor antagonists
MX2021001433A (es) Nuevos compuestos heterociclicos como inhibidores de la monoacilglicerol lipasa.
ATE324373T1 (de) Immunmodulierende verbindungen
WO2004074244A3 (en) Pyrimidine compounds
BR0311343A (pt) Derivados de piridazina
NO20063196L (no) Nye fusjonerte pyrrolokarbazoler
HUP0500136A2 (hu) Oxitocin antagonista hatású szubsztituált diketo-piperazinok, eljárás előállításukra, az ezeket tartalmazó gyógyszerkészítmények és alkalmazásuk
SE0200919D0 (sv) Chemical compounds
WO2003087062A3 (en) 4-(heterocyclyl)-benzenesulfoximine compounds for the treatment of inflammation
MXPA05007607A (es) Inhibidores amida y ester de la metaloproteinasa de matriz.
WO2006079720A8 (fr) Nouveaux derives d1oximes heterocycliques, leur procede de preparation et leur utilisation comme agents hypoglycemiants et hypoli pemiants
HK1075663A1 (en) Novel heteroaryl-substituted acetone derivatives as inhibitors of phospholipase a sb 2 /sb
ATE425164T1 (de) Tetrazyklische immunmodulierende verbindungen
HK1061845A1 (en) New process for the industrial synthesis of substituted thiophenecarboxylates, and application of such compounds
GB0412314D0 (en) Compounds
WO2003080631A3 (en) Plasma carboxypeptidase b inhibitors
WO2004024060A3 (en) Metalloproteinase inhibitors and intermediates for preparation thereof
WO2003076426A3 (en) Pyridinyloxy derivatives as 5-ht receptor ligands
ATE327987T1 (de) Methylthiophencarboxanilide
WO2005025492A3 (en) Novel compositions, pharmaceutical compositions, and methods for the treatment and prevention of heart disease
MX2021007505A (es) Síntesis de 3-metil-1,2,4-tiadiazol-5-carbohidrazida o de su forma deuterada con metil-d3.
WO2007009080A3 (en) Ppar [alpha/gamma] agonists and processes of preparing

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties