ATE322263T1 - Verbessertes transdermales abgabesystem für die verabreichung von rotigotin - Google Patents
Verbessertes transdermales abgabesystem für die verabreichung von rotigotinInfo
- Publication number
- ATE322263T1 ATE322263T1 AT03766331T AT03766331T ATE322263T1 AT E322263 T1 ATE322263 T1 AT E322263T1 AT 03766331 T AT03766331 T AT 03766331T AT 03766331 T AT03766331 T AT 03766331T AT E322263 T1 ATE322263 T1 AT E322263T1
- Authority
- AT
- Austria
- Prior art keywords
- rotigotine
- matrix
- tds
- delivery system
- transdermal delivery
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
- A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
- A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
- A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
- A61K9/7061—Polyacrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
- A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
- A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
- A61K9/7069—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained otherwise than by reactions only involving carbon to carbon unsaturated bonds, e.g. polysiloxane, polyesters, polyurethane, polyethylene oxide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP02016860A EP1386605A1 (de) | 2002-07-30 | 2002-07-30 | Verbessertes transdermales System für die Verabreichung von Rotigotin |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE322263T1 true ATE322263T1 (de) | 2006-04-15 |
Family
ID=30011090
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT03766331T ATE322263T1 (de) | 2002-07-30 | 2003-07-28 | Verbessertes transdermales abgabesystem für die verabreichung von rotigotin |
Country Status (19)
Country | Link |
---|---|
EP (2) | EP1386605A1 (de) |
JP (2) | JP4837916B2 (de) |
KR (1) | KR101016838B1 (de) |
CN (2) | CN101953819A (de) |
AT (1) | ATE322263T1 (de) |
AU (1) | AU2003258539B2 (de) |
BR (1) | BR0313091A (de) |
CA (1) | CA2491366A1 (de) |
DE (1) | DE60304477T2 (de) |
DK (1) | DK1524975T3 (de) |
ES (1) | ES2256780T3 (de) |
IL (1) | IL165918A0 (de) |
MX (1) | MXPA05000350A (de) |
NO (1) | NO333297B1 (de) |
PL (1) | PL217079B1 (de) |
PT (1) | PT1524975E (de) |
SI (1) | SI1524975T1 (de) |
WO (1) | WO2004012730A1 (de) |
ZA (1) | ZA200500252B (de) |
Families Citing this family (31)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1386605A1 (de) * | 2002-07-30 | 2004-02-04 | Schwarz Pharma Ag | Verbessertes transdermales System für die Verabreichung von Rotigotin |
EP1386604A1 (de) * | 2002-07-30 | 2004-02-04 | Schwarz Pharma Ag | Verbessertes transdermales Verabreichungssystem |
DE10361259A1 (de) * | 2003-12-24 | 2005-07-28 | Schwarz Pharma Ag | Verwendung von Rotigotine in einem Frühstadium von Morbus Parkinson zur Prävention des weiteren Neuronenverlustes |
DE10361258A1 (de) | 2003-12-24 | 2005-07-28 | Schwarz Pharma Ag | Verwendung von substituierten 2-Aminotetralinen zur vorbeugenden Behandlung von Morbus Parkinson |
DE102004014841B4 (de) | 2004-03-24 | 2006-07-06 | Schwarz Pharma Ag | Verwendung von Rotigotin zur Behandlung und Prävention des Parkinson-Plus-Syndroms |
WO2006039532A2 (en) * | 2004-09-29 | 2006-04-13 | Schwarz Pharma, Inc. | Transdermal therapeutic system for parkinson’s disease |
US7353034B2 (en) | 2005-04-04 | 2008-04-01 | X One, Inc. | Location sharing and tracking using mobile phones or other wireless devices |
CN102281873A (zh) * | 2008-10-06 | 2011-12-14 | 迈兰技术有限公司 | 非晶罗替戈汀(rotigotine)透皮系统 |
DE102008060203A1 (de) | 2008-12-07 | 2010-06-10 | Dietrich Wilhelm Schacht | Wirkstoffstabilisierende flächenförmige Vorrichtung |
EP2201941A1 (de) | 2008-12-29 | 2010-06-30 | UCB Pharma GmbH | Pflaster-Herstellungstechnologie |
HUE039447T2 (hu) | 2009-12-22 | 2018-12-28 | Ucb Biopharma Sprl | Polivinilpirrolidon rotigotin nem kristályos formája szilárd diszperziójának stabilizálására |
JP5820469B2 (ja) | 2010-04-30 | 2015-11-24 | テイコク ファーマ ユーエスエー インコーポレーテッド | プロピニルアミノインダンの経皮組成物 |
CN103476404B (zh) | 2011-03-24 | 2017-09-29 | 帝国制药美国公司 | 包含活性剂层和活性剂转化层的透皮组合物 |
EP2559435A1 (de) | 2011-08-19 | 2013-02-20 | UCB Pharma GmbH | Rotigotin in der Behandlung von Hemineglekt, Schlaganfall und Defiziten nach einem Schlaganfall |
JP5913614B2 (ja) | 2011-11-09 | 2016-04-27 | テイコク ファーマ ユーエスエー インコーポレーテッド | 皮膚新生物の処置方法 |
DE102011119043A1 (de) | 2011-11-22 | 2013-05-23 | Alfred E. Tiefenbacher (Gmbh & Co. Kg) | Transdermales therapeutisches System (TDS) mit Rotigotin |
DE102011090178A1 (de) * | 2011-12-30 | 2013-07-04 | Lts Lohmann Therapie-Systeme Ag | Transdermales therapeutisches System mit geringer Neigung zur Spontankristallisation |
CA2878376C (en) * | 2012-07-05 | 2018-08-07 | Sk Chemicals Co., Ltd. | Transdermally absorbable preparation containing rotigotine |
JP6050896B2 (ja) | 2012-11-02 | 2016-12-21 | テイコク ファーマ ユーエスエー インコーポレーテッド | プロピニルアミノインダン経皮組成物 |
TW201431570A (zh) | 2012-11-22 | 2014-08-16 | Ucb Pharma Gmbh | 用於經皮投服羅替戈汀(Rotigotine)之多天式貼片 |
JP2016135744A (ja) * | 2013-05-08 | 2016-07-28 | 株式会社 ケイ・エム トランスダーム | 貼付剤 |
WO2014198422A1 (de) | 2013-06-14 | 2014-12-18 | Tesa Labtec Gmbh | Transdermales therapiesystem (tts) mit rotigotin |
WO2014198423A1 (de) | 2013-06-14 | 2014-12-18 | Tesa Labtec Gmbh | Dreischichtiges transdermales therapiesystem (tts) |
ES2694662T3 (es) | 2013-07-03 | 2018-12-26 | Lts Lohmann Therapie-Systeme Ag | Sistema terapéutico transdérmico con componente electrónico |
US11633367B2 (en) | 2014-05-20 | 2023-04-25 | Lts Lohmann Therapie-Systeme Ag | Transdermal delivery system containing rotigotine |
JP6895755B2 (ja) * | 2014-05-20 | 2021-06-30 | エルテーエス ローマン テラピー−ジステーメ アーゲー | 経皮送達システムにおける活性薬剤の放出を調節するための方法 |
ES2954087T3 (es) | 2014-05-20 | 2023-11-20 | Lts Lohmann Therapie Systeme Ag | Sistema de administración transdérmica que incluye un mediador de interfase |
KR102364378B1 (ko) | 2014-05-21 | 2022-02-16 | 에스케이케미칼 주식회사 | 안정성을 향상시킨 로티고틴 함유 경피흡수제제 |
CN104382850B (zh) * | 2014-10-17 | 2017-12-22 | 烟台大学 | 一种罗替戈汀微乳及微乳凝胶 |
WO2019234662A1 (en) * | 2018-06-07 | 2019-12-12 | Nal Pharmaceutical Group Limited | Transdermal drug delivery system containing rotigotine |
PT3854388T (pt) | 2020-01-24 | 2023-12-11 | Luye Pharma Switzerland Ag | Sistema terapêutico transdérmico com o princípio ativo rotigotina e pelo menos um adesivo de silicone não resistente a aminas |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5989586A (en) * | 1992-10-05 | 1999-11-23 | Cygnus, Inc. | Two-phase matrix for sustained release drug delivery device |
AUPN814496A0 (en) * | 1996-02-19 | 1996-03-14 | Monash University | Dermal penetration enhancer |
DE19814083C2 (de) * | 1998-03-30 | 2002-02-07 | Lohmann Therapie Syst Lts | Verfahren zur Herstellung von transdermalen therapeutischen Systemen unter Verwendung von basischen Alkalimetallsalzen zur Umwandlung von Wirkstoffsalzen in die freien Basen |
DE19814084B4 (de) * | 1998-03-30 | 2005-12-22 | Lts Lohmann Therapie-Systeme Ag | D2-Agonist enthaltendes transdermales therapeutisches System zur Behandlung des Parkinson-Syndroms und Verfahren zu seiner Herstellung |
DE19940238A1 (de) * | 1999-08-25 | 2001-03-01 | Lohmann Therapie Syst Lts | Wirkstoffhaltiges therapeutisches System zur Applikation auf der Haut mit mindestens zwei polymerhaltigen Schichten |
ES2203563T3 (es) * | 2001-05-08 | 2004-04-16 | Schwarz Pharma Ag | Sistema terapeutico transdermico mejorado para el tratamiento de la enfermedad de parkinson. |
EP1386604A1 (de) * | 2002-07-30 | 2004-02-04 | Schwarz Pharma Ag | Verbessertes transdermales Verabreichungssystem |
EP1386605A1 (de) * | 2002-07-30 | 2004-02-04 | Schwarz Pharma Ag | Verbessertes transdermales System für die Verabreichung von Rotigotin |
-
2002
- 2002-07-30 EP EP02016860A patent/EP1386605A1/de not_active Withdrawn
-
2003
- 2003-07-28 CN CN2010102984651A patent/CN101953819A/zh active Pending
- 2003-07-28 WO PCT/EP2003/008320 patent/WO2004012730A1/en active IP Right Grant
- 2003-07-28 DK DK03766331T patent/DK1524975T3/da active
- 2003-07-28 PL PL374814A patent/PL217079B1/pl unknown
- 2003-07-28 CN CNA038184257A patent/CN1671375A/zh active Pending
- 2003-07-28 JP JP2004525349A patent/JP4837916B2/ja not_active Expired - Lifetime
- 2003-07-28 CA CA002491366A patent/CA2491366A1/en not_active Abandoned
- 2003-07-28 EP EP03766331A patent/EP1524975B9/de not_active Expired - Lifetime
- 2003-07-28 BR BR0313091-6A patent/BR0313091A/pt not_active Application Discontinuation
- 2003-07-28 AU AU2003258539A patent/AU2003258539B2/en not_active Expired
- 2003-07-28 DE DE60304477T patent/DE60304477T2/de not_active Expired - Lifetime
- 2003-07-28 SI SI200330224T patent/SI1524975T1/sl unknown
- 2003-07-28 AT AT03766331T patent/ATE322263T1/de active
- 2003-07-28 PT PT03766331T patent/PT1524975E/pt unknown
- 2003-07-28 ES ES03766331T patent/ES2256780T3/es not_active Expired - Lifetime
- 2003-07-28 KR KR1020057001233A patent/KR101016838B1/ko active IP Right Grant
- 2003-07-28 MX MXPA05000350A patent/MXPA05000350A/es active IP Right Grant
-
2004
- 2004-12-22 IL IL16591804A patent/IL165918A0/xx unknown
-
2005
- 2005-01-11 ZA ZA2005/00252A patent/ZA200500252B/en unknown
- 2005-01-27 NO NO20050472A patent/NO333297B1/no not_active IP Right Cessation
-
2011
- 2011-06-15 JP JP2011133638A patent/JP5564469B2/ja not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
NO333297B1 (no) | 2013-04-29 |
JP2011219485A (ja) | 2011-11-04 |
NO20050472L (no) | 2005-01-27 |
DE60304477D1 (de) | 2006-05-18 |
PL217079B1 (pl) | 2014-06-30 |
ES2256780T3 (es) | 2006-07-16 |
PL374814A1 (en) | 2005-10-31 |
WO2004012730A1 (en) | 2004-02-12 |
EP1524975B1 (de) | 2006-04-05 |
JP5564469B2 (ja) | 2014-07-30 |
CA2491366A1 (en) | 2004-02-12 |
PT1524975E (pt) | 2006-07-31 |
EP1386605A1 (de) | 2004-02-04 |
BR0313091A (pt) | 2005-06-21 |
DK1524975T3 (da) | 2006-07-31 |
AU2003258539A1 (en) | 2004-02-23 |
AU2003258539B2 (en) | 2008-08-21 |
MXPA05000350A (es) | 2005-03-31 |
EP1524975A1 (de) | 2005-04-27 |
EP1524975B9 (de) | 2012-02-22 |
JP2005535687A (ja) | 2005-11-24 |
CN101953819A (zh) | 2011-01-26 |
KR101016838B1 (ko) | 2011-02-22 |
CN1671375A (zh) | 2005-09-21 |
KR20050056942A (ko) | 2005-06-16 |
ZA200500252B (en) | 2006-01-25 |
JP4837916B2 (ja) | 2011-12-14 |
SI1524975T1 (sl) | 2006-06-30 |
IL165918A0 (en) | 2006-01-15 |
DE60304477T2 (de) | 2006-12-14 |
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