ATE322263T1 - Verbessertes transdermales abgabesystem für die verabreichung von rotigotin - Google Patents

Verbessertes transdermales abgabesystem für die verabreichung von rotigotin

Info

Publication number
ATE322263T1
ATE322263T1 AT03766331T AT03766331T ATE322263T1 AT E322263 T1 ATE322263 T1 AT E322263T1 AT 03766331 T AT03766331 T AT 03766331T AT 03766331 T AT03766331 T AT 03766331T AT E322263 T1 ATE322263 T1 AT E322263T1
Authority
AT
Austria
Prior art keywords
rotigotine
matrix
tds
delivery system
transdermal delivery
Prior art date
Application number
AT03766331T
Other languages
English (en)
Inventor
Mike Hannay
Dietrich Wilhelm Schacht
Hans-Michael Wolff
Original Assignee
Sanol Arznei Schwarz Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanol Arznei Schwarz Gmbh filed Critical Sanol Arznei Schwarz Gmbh
Application granted granted Critical
Publication of ATE322263T1 publication Critical patent/ATE322263T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
    • A61K9/7061—Polyacrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7069—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained otherwise than by reactions only involving carbon to carbon unsaturated bonds, e.g. polysiloxane, polyesters, polyurethane, polyethylene oxide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Psychology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AT03766331T 2002-07-30 2003-07-28 Verbessertes transdermales abgabesystem für die verabreichung von rotigotin ATE322263T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP02016860A EP1386605A1 (de) 2002-07-30 2002-07-30 Verbessertes transdermales System für die Verabreichung von Rotigotin

Publications (1)

Publication Number Publication Date
ATE322263T1 true ATE322263T1 (de) 2006-04-15

Family

ID=30011090

Family Applications (1)

Application Number Title Priority Date Filing Date
AT03766331T ATE322263T1 (de) 2002-07-30 2003-07-28 Verbessertes transdermales abgabesystem für die verabreichung von rotigotin

Country Status (19)

Country Link
EP (2) EP1386605A1 (de)
JP (2) JP4837916B2 (de)
KR (1) KR101016838B1 (de)
CN (2) CN101953819A (de)
AT (1) ATE322263T1 (de)
AU (1) AU2003258539B2 (de)
BR (1) BR0313091A (de)
CA (1) CA2491366A1 (de)
DE (1) DE60304477T2 (de)
DK (1) DK1524975T3 (de)
ES (1) ES2256780T3 (de)
IL (1) IL165918A0 (de)
MX (1) MXPA05000350A (de)
NO (1) NO333297B1 (de)
PL (1) PL217079B1 (de)
PT (1) PT1524975E (de)
SI (1) SI1524975T1 (de)
WO (1) WO2004012730A1 (de)
ZA (1) ZA200500252B (de)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10041478A1 (de) 2000-08-24 2002-03-14 Sanol Arznei Schwarz Gmbh Neue pharmazeutische Zusammensetzung
EP1386604A1 (de) * 2002-07-30 2004-02-04 Schwarz Pharma Ag Verbessertes transdermales Verabreichungssystem
EP1386605A1 (de) * 2002-07-30 2004-02-04 Schwarz Pharma Ag Verbessertes transdermales System für die Verabreichung von Rotigotin
DE10361259A1 (de) * 2003-12-24 2005-07-28 Schwarz Pharma Ag Verwendung von Rotigotine in einem Frühstadium von Morbus Parkinson zur Prävention des weiteren Neuronenverlustes
DE10361258A1 (de) 2003-12-24 2005-07-28 Schwarz Pharma Ag Verwendung von substituierten 2-Aminotetralinen zur vorbeugenden Behandlung von Morbus Parkinson
DE102004014841B4 (de) 2004-03-24 2006-07-06 Schwarz Pharma Ag Verwendung von Rotigotin zur Behandlung und Prävention des Parkinson-Plus-Syndroms
WO2006039532A2 (en) * 2004-09-29 2006-04-13 Schwarz Pharma, Inc. Transdermal therapeutic system for parkinson’s disease
US7353034B2 (en) 2005-04-04 2008-04-01 X One, Inc. Location sharing and tracking using mobile phones or other wireless devices
EP2742934A1 (de) * 2008-10-06 2014-06-18 Mylan Technologies, Inc. Amorphes transdermales Rotigotin-System
DE102008060203A1 (de) 2008-12-07 2010-06-10 Dietrich Wilhelm Schacht Wirkstoffstabilisierende flächenförmige Vorrichtung
EP2201941A1 (de) 2008-12-29 2010-06-30 UCB Pharma GmbH Pflaster-Herstellungstechnologie
PL3257504T3 (pl) * 2009-12-22 2024-10-21 UCB Biopharma SRL Poliwinylopirolidon do stabilizacji stałej dyspersji niekrystalicznej postaci rotygotyny
CA2793571C (en) 2010-04-30 2015-10-13 Teikoku Pharma Usa, Inc. Propynylaminoindan transdermal compositions
WO2012129429A2 (en) 2011-03-24 2012-09-27 Teikoku Pharma Usa, Inc. Transdermal compositions comprising an active agent layer and an active agent conversion layer
EP2559435A1 (de) 2011-08-19 2013-02-20 UCB Pharma GmbH Rotigotin in der Behandlung von Hemineglekt, Schlaganfall und Defiziten nach einem Schlaganfall
US9913812B2 (en) 2011-11-09 2018-03-13 Teikoku Pharma Usa, Inc. Methods for the treatment of skin neoplasms
DE102011119043A1 (de) 2011-11-22 2013-05-23 Alfred E. Tiefenbacher (Gmbh & Co. Kg) Transdermales therapeutisches System (TDS) mit Rotigotin
DE102011090178A1 (de) 2011-12-30 2013-07-04 Lts Lohmann Therapie-Systeme Ag Transdermales therapeutisches System mit geringer Neigung zur Spontankristallisation
AU2013285733B2 (en) * 2012-07-05 2016-11-10 Sk Chemicals Co., Ltd. Transdermally absorbable preparation containing rotigotine
KR101856515B1 (ko) 2012-11-02 2018-05-10 테이코쿠 팔마 유에스에이, 인코포레이티드 프로피닐아미노인단 경피 조성물
TW201431570A (zh) 2012-11-22 2014-08-16 Ucb Pharma Gmbh 用於經皮投服羅替戈汀（Ｒｏｔｉｇｏｔｉｎｅ）之多天式貼片
JP2016135744A (ja) * 2013-05-08 2016-07-28 株式会社 ケイ・エム トランスダーム 貼付剤
WO2014198422A1 (de) 2013-06-14 2014-12-18 Tesa Labtec Gmbh Transdermales therapiesystem (tts) mit rotigotin
WO2014198423A1 (de) 2013-06-14 2014-12-18 Tesa Labtec Gmbh Dreischichtiges transdermales therapiesystem (tts)
ES2694662T3 (es) 2013-07-03 2018-12-26 Lts Lohmann Therapie-Systeme Ag Sistema terapéutico transdérmico con componente electrónico
CN106456568B (zh) 2014-05-20 2020-03-27 Lts勒曼治疗系统股份公司 包含界面调节剂的经皮递送系统
CN106456567A (zh) * 2014-05-20 2017-02-22 Lts勒曼治疗系统股份公司 在经皮递送系统中调节活性剂释放的方法
EP3145502B1 (de) * 2014-05-20 2022-07-06 LTS Lohmann Therapie-Systeme AG Transdermales abgabesystem mit rotigotin
KR102364378B1 (ko) * 2014-05-21 2022-02-16 에스케이케미칼 주식회사 안정성을 향상시킨 로티고틴 함유 경피흡수제제
CN104382850B (zh) * 2014-10-17 2017-12-22 烟台大学 一种罗替戈汀微乳及微乳凝胶
WO2019234662A1 (en) * 2018-06-07 2019-12-12 Nal Pharmaceutical Group Limited Transdermal drug delivery system containing rotigotine
DK3854388T3 (da) 2020-01-24 2023-11-27 Luye Pharma Switzerland Ag Transdermalt terapeutisk system omfattende rotigotin og mindst et ikke-aminresistent silikoneklæbestof

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Publication number Priority date Publication date Assignee Title
US5989586A (en) * 1992-10-05 1999-11-23 Cygnus, Inc. Two-phase matrix for sustained release drug delivery device
AUPN814496A0 (en) * 1996-02-19 1996-03-14 Monash University Dermal penetration enhancer
DE19814084B4 (de) * 1998-03-30 2005-12-22 Lts Lohmann Therapie-Systeme Ag D2-Agonist enthaltendes transdermales therapeutisches System zur Behandlung des Parkinson-Syndroms und Verfahren zu seiner Herstellung
DE19814083C2 (de) * 1998-03-30 2002-02-07 Lohmann Therapie Syst Lts Verfahren zur Herstellung von transdermalen therapeutischen Systemen unter Verwendung von basischen Alkalimetallsalzen zur Umwandlung von Wirkstoffsalzen in die freien Basen
DE19940238A1 (de) * 1999-08-25 2001-03-01 Lohmann Therapie Syst Lts Wirkstoffhaltiges therapeutisches System zur Applikation auf der Haut mit mindestens zwei polymerhaltigen Schichten
EP1256340B1 (de) * 2001-05-08 2003-08-13 Schwarz Pharma Ag Verbessertes transdermales therapeutisches System zur Behandlung von Morbus Parkinson
EP1386605A1 (de) * 2002-07-30 2004-02-04 Schwarz Pharma Ag Verbessertes transdermales System für die Verabreichung von Rotigotin
EP1386604A1 (de) * 2002-07-30 2004-02-04 Schwarz Pharma Ag Verbessertes transdermales Verabreichungssystem

Also Published As

Publication number Publication date
JP2011219485A (ja) 2011-11-04
KR20050056942A (ko) 2005-06-16
PL374814A1 (en) 2005-10-31
CN101953819A (zh) 2011-01-26
JP4837916B2 (ja) 2011-12-14
DK1524975T3 (da) 2006-07-31
NO333297B1 (no) 2013-04-29
EP1524975B9 (de) 2012-02-22
BR0313091A (pt) 2005-06-21
JP5564469B2 (ja) 2014-07-30
DE60304477D1 (de) 2006-05-18
AU2003258539A1 (en) 2004-02-23
PL217079B1 (pl) 2014-06-30
IL165918A0 (en) 2006-01-15
EP1524975B1 (de) 2006-04-05
EP1386605A1 (de) 2004-02-04
NO20050472L (no) 2005-01-27
WO2004012730A1 (en) 2004-02-12
PT1524975E (pt) 2006-07-31
AU2003258539B2 (en) 2008-08-21
KR101016838B1 (ko) 2011-02-22
CA2491366A1 (en) 2004-02-12
CN1671375A (zh) 2005-09-21
MXPA05000350A (es) 2005-03-31
ES2256780T3 (es) 2006-07-16
ZA200500252B (en) 2006-01-25
SI1524975T1 (sl) 2006-06-30
JP2005535687A (ja) 2005-11-24
DE60304477T2 (de) 2006-12-14
EP1524975A1 (de) 2005-04-27

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