ATE321064T1 - Sulfatierte polysaccharide und verfahren zur behandlung von entzündungen unter verwendung derselben - Google Patents

Sulfatierte polysaccharide und verfahren zur behandlung von entzündungen unter verwendung derselben

Info

Publication number
ATE321064T1
ATE321064T1 AT02734003T AT02734003T ATE321064T1 AT E321064 T1 ATE321064 T1 AT E321064T1 AT 02734003 T AT02734003 T AT 02734003T AT 02734003 T AT02734003 T AT 02734003T AT E321064 T1 ATE321064 T1 AT E321064T1
Authority
AT
Austria
Prior art keywords
same
treating inflammation
sulfated polysaccharides
sulfated
polysaccharides
Prior art date
Application number
AT02734003T
Other languages
English (en)
Inventor
Tahir Ahmed
Gregory A Smith
Original Assignee
Ivax Research Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ivax Research Inc filed Critical Ivax Research Inc
Application granted granted Critical
Publication of ATE321064T1 publication Critical patent/ATE321064T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
    • C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
    • C08B37/0075—Heparin; Heparan sulfate; Derivatives thereof, e.g. heparosan; Purification or extraction methods thereof
    • C08B37/0078—Degradation products
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7024—Esters of saccharides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/02—Nasal agents, e.g. decongestants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/14—Antitussive agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/14—Decongestants or antiallergics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H11/00—Compounds containing saccharide radicals esterified by inorganic acids; Metal salts thereof
    • C—CHEMISTRY; METALLURGY
    • C40—COMBINATORIAL TECHNOLOGY
    • C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B40/00—Libraries per se, e.g. arrays, mixtures
AT02734003T 2001-04-16 2002-04-16 Sulfatierte polysaccharide und verfahren zur behandlung von entzündungen unter verwendung derselben ATE321064T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US28479001P 2001-04-16 2001-04-16

Publications (1)

Publication Number Publication Date
ATE321064T1 true ATE321064T1 (de) 2006-04-15

Family

ID=23091543

Family Applications (1)

Application Number Title Priority Date Filing Date
AT02734003T ATE321064T1 (de) 2001-04-16 2002-04-16 Sulfatierte polysaccharide und verfahren zur behandlung von entzündungen unter verwendung derselben

Country Status (13)

Country Link
US (1) US7056898B2 (de)
EP (1) EP1381620B1 (de)
JP (1) JP2005510453A (de)
KR (1) KR20040008157A (de)
AR (1) AR035827A1 (de)
AT (1) ATE321064T1 (de)
CA (1) CA2444761A1 (de)
DE (1) DE60210070T2 (de)
DK (1) DK1381620T3 (de)
ES (1) ES2258145T3 (de)
NZ (1) NZ529036A (de)
PT (1) PT1381620E (de)
WO (1) WO2002083700A2 (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005075490A2 (en) * 2004-02-03 2005-08-18 Ivax Corporation Synthesis of polysulfated uronic acid glycosides
EP1731131A1 (de) * 2004-03-29 2006-12-13 Kringle Pharma Inc. Hgf-produktionsbeschleuniger mit heparinähnlichem oligosaccharid
AU2005271349B2 (en) 2004-08-05 2011-10-27 Ivax Drug Research Institute Ltd Polysulfated glycosides and salts thereof
US20080249165A1 (en) * 2004-08-05 2008-10-09 Ivax Drug Research Institute Ltd. Glycosides and Salts Thereof
CA2781923C (en) 2009-12-03 2018-08-14 Opko Health, Inc. Hypersulfated disaccharide formulations
JP2014500863A (ja) * 2010-10-29 2014-01-16 オプコ ヘルス インコーポレイテッド エラスターゼ関連障害を治療するための高硫酸化二糖
JP5871500B2 (ja) * 2011-06-20 2016-03-01 公益財団法人先端医療振興財団 α−Ｋｌｏｔｈｏ／ＦＧＦ２３複合体形成阻害化合物
EP3500583A1 (de) 2016-08-16 2019-06-26 OPKO Pharmaceuticals, LLC Reine heptasulfatierte disaccharide mit verbesserter oraler bioverfügbarkeit

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL85145A (en) 1987-01-23 1994-08-26 Univ Australian Anti-metastatic pharmacological or veterinary preparations containing modified herpin with reduced anticoagulant activity
US5827886A (en) * 1997-05-07 1998-10-27 Thione International, Inc. Composition for relief of arthritis-induced symptoms

Also Published As

Publication number Publication date
DE60210070D1 (de) 2006-05-11
NZ529036A (en) 2005-11-25
ES2258145T3 (es) 2006-08-16
US20030087875A1 (en) 2003-05-08
DE60210070T2 (de) 2006-12-07
EP1381620A2 (de) 2004-01-21
WO2002083700A3 (en) 2003-04-17
PT1381620E (pt) 2006-06-30
WO2002083700B1 (en) 2003-09-18
JP2005510453A (ja) 2005-04-21
KR20040008157A (ko) 2004-01-28
AR035827A1 (es) 2004-07-14
EP1381620B1 (de) 2006-03-22
CA2444761A1 (en) 2002-10-24
US7056898B2 (en) 2006-06-06
WO2002083700A2 (en) 2002-10-24
DK1381620T3 (da) 2006-06-26

Similar Documents

Publication Publication Date Title
DE50010492D1 (de) Verfahren und Vorrichtung zur Herstellung von Einzelglasscheiben
DE60016209D1 (de) Hemisynthetisches verfahren und dessen zwischenprudukte
DE60036963D1 (de) Filteranordnung und verfahren zur wartung
DE60122532D1 (de) Verfahren zur behandlung von mehreren bohrlochintervallen
ATE241647T1 (de) Verfahren und vorrichtung zur herstellung von celluloseethern
ATE339185T1 (de) Verfahren zur behandlung von entzündungsbedingten zuständen der augen
DE69928218D1 (de) Pumpen und regelunssystem und dessen verfahren
DE50113041D1 (de) Verfahren und vorrichtung zur herstellung von dünnen glasscheiben
DE60042806D1 (de) Verfahren und Vorrichtung zur Herstellung von in Längsrichtung angeordneten Vliesstoffen
DE50007778D1 (de) Reinigungselement, insbesondere zur reinigung von zähnen und verfahren zu seiner herstellung
DE69818648D1 (de) Verfahren zur behandlung keimblättriger pflanzen
DE60114439D1 (de) Verfahren zur antimikrobiellen behandlung von fasermaterialien
DE50208266D1 (de) Verfahren und system zur unterstützung der projektierung von fertigungsanlagen
DE60021960D1 (de) Verfahren zur Kompensation von Neigung und/oder Defokussierung, und Vorrichtung für dasselbige
ATE321064T1 (de) Sulfatierte polysaccharide und verfahren zur behandlung von entzündungen unter verwendung derselben
DE60039778D1 (de) Verfahren und vorrichtung zur automatisierung der
DE69810449D1 (de) Verfahren zur behandlung von keimblättrigen pflanzen
DE50213931D1 (de) Verfahren und vorrichtung zur behandlung von fehlerverdacht
DE60110878D1 (de) Verfahren zur Objektfiltrierung und Klientgerät unter Verwendung desselben
ATE402761T1 (de) Katalysatorzusammensetzung und verfahren unter verwendung dieser zusammensetzung
DE1231998T1 (de) Filtervorrichtung und verfahren zur waschung der filterelemente
ATA20122001A (de) Verfahren zur behandlung von cellulosischen formkörpern
ATE335665T1 (de) System und verfahren zur herstellung von lasteinheiten
DE60025417D1 (de) Verfahren und Vorrichtung zur Herstellung von zweifarbigen Elementen
ATE307871T1 (de) Verfahren zur behandlung von gewebe

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification

Ref document number: 1381620

Country of ref document: EP