ATE318600T1 - Diaryl piperidyl-pyrrol-derivate als antiprotozoenmittel - Google Patents

Diaryl piperidyl-pyrrol-derivate als antiprotozoenmittel

Info

Publication number
ATE318600T1
ATE318600T1 AT00978439T AT00978439T ATE318600T1 AT E318600 T1 ATE318600 T1 AT E318600T1 AT 00978439 T AT00978439 T AT 00978439T AT 00978439 T AT00978439 T AT 00978439T AT E318600 T1 ATE318600 T1 AT E318600T1
Authority
AT
Austria
Prior art keywords
diaryl
piperidyl
pyrrole derivatives
antiprotozoal agents
antiprotozoal
Prior art date
Application number
AT00978439T
Other languages
German (de)
English (en)
Inventor
Tesfaye Biftu
Danqing D Feng
Gui-Bai Liang
Mitree M Ponpipom
Xiaoxia Qian
Michael H Fisher
Matthew J Wyvratt
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Application granted granted Critical
Publication of ATE318600T1 publication Critical patent/ATE318600T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K20/00Accessory food factors for animal feeding-stuffs
    • A23K20/10Organic substances
    • A23K20/116Heterocyclic compounds
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K50/00Feeding-stuffs specially adapted for particular animals
    • A23K50/70Feeding-stuffs specially adapted for particular animals for birds
    • A23K50/75Feeding-stuffs specially adapted for particular animals for birds for poultry
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • A61P33/02Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Polymers & Plastics (AREA)
  • Veterinary Medicine (AREA)
  • Birds (AREA)
  • Animal Husbandry (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Food Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyrrole Compounds (AREA)
AT00978439T 1999-11-12 2000-11-09 Diaryl piperidyl-pyrrol-derivate als antiprotozoenmittel ATE318600T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US16514299P 1999-11-12 1999-11-12

Publications (1)

Publication Number Publication Date
ATE318600T1 true ATE318600T1 (de) 2006-03-15

Family

ID=22597609

Family Applications (1)

Application Number Title Priority Date Filing Date
AT00978439T ATE318600T1 (de) 1999-11-12 2000-11-09 Diaryl piperidyl-pyrrol-derivate als antiprotozoenmittel

Country Status (11)

Country Link
US (2) US6291480B1 (https=)
EP (1) EP1278520B1 (https=)
JP (1) JP4722360B2 (https=)
AT (1) ATE318600T1 (https=)
AU (1) AU781552B2 (https=)
CA (1) CA2390100C (https=)
DE (1) DE60026350T2 (https=)
ES (1) ES2257336T3 (https=)
NZ (1) NZ518718A (https=)
WO (1) WO2001034149A1 (https=)
ZA (1) ZA200203685B (https=)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001034150A1 (en) * 1999-11-12 2001-05-17 Merck & Co., Inc. Aliphatic amine substituted piperidyl diaryl pyrrole derivatives as antiprotozoal agents
GB0112348D0 (en) 2001-05-19 2001-07-11 Smithkline Beecham Plc Compounds
EP1414948B1 (en) * 2001-07-10 2009-09-16 Biogen Idec Inc. Inhibition of apoptosis process and improvement of cell performance
US7375105B2 (en) 2001-09-05 2008-05-20 Smithkline Beecham P.L.C. Pyridine substituted furan derivatives as Raf kinase inhibitors
EP1632488A1 (en) * 2003-06-11 2006-03-08 Sankyo Company, Limited Cyclic tertiary amine compound
WO2007056457A2 (en) 2005-11-09 2007-05-18 Combinatorx, Incorporated Methods, compositions, and kits for the treatment of medical conditions
WO2014121342A1 (en) * 2013-02-08 2014-08-14 Luoda Pharma Pty Limited Methods of treating topical microbial infections
RU2659205C1 (ru) * 2017-06-01 2018-06-28 Федеральное государственное бюджетное научное учреждение "Прикаспийский зональный научно-исследовательский ветеринарный институт" Способ профилактики кокцидиоза цыплят-бройлеров при выращивании их на мясо
BE1028700B1 (nl) * 2020-10-13 2022-05-16 Poulpharm Bvba Werkwijze voor het testen van de efficiëntie van anti-parasitaire (coccidiose) middelen bij pluimvee en konijnen
WO2025085377A1 (en) * 2023-10-16 2025-04-24 Zoetis Services Llc Use of zoalene in livestock
WO2025171002A1 (en) * 2024-02-05 2025-08-14 Elanco Us Inc. Multi-layered granule therapeutics

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4153703A (en) * 1977-06-30 1979-05-08 Uniroyal, Inc. Method of controlling insects and acarids with certain aryl-substituted thiazoles
WO1996017841A1 (en) * 1994-12-06 1996-06-13 Nippon Soda Co., Ltd. Pyridylpyrrole compounds, process for production, and agrohorticultural bactericide
US5792778A (en) * 1995-08-10 1998-08-11 Merck & Co., Inc. 2-substituted aryl pyrroles, compositions containing such compounds and methods of use
WO1997005877A1 (en) * 1995-08-10 1997-02-20 Merck & Co., Inc. 2-substituted aryl pyrroles, compositions containing such compounds and methods of use
AU7529096A (en) * 1995-10-31 1997-05-22 Merck & Co., Inc. Substituted aryl pyrroles, compositions containing such compounds and methods of use
JPH09194477A (ja) * 1996-01-18 1997-07-29 Nippon Soda Co Ltd 新規なピリジルピロール化合物、製法および農園芸用殺菌剤
WO1997048725A1 (en) * 1996-06-21 1997-12-24 Peptech Limited Novel peptides for prevention and treatment of infection
WO2000001688A1 (en) * 1998-07-02 2000-01-13 Sankyo Company, Limited Five-membered heteroaryl compounds
JP2000080094A (ja) * 1998-07-02 2000-03-21 Sankyo Co Ltd 5員ヘテロアリ―ル化合物
WO2000066124A1 (fr) * 1999-04-28 2000-11-09 Sankyo Company, Limited Agents preventifs ou inhibiteurs destines a une hepatopathie
JP2001010957A (ja) * 1999-04-28 2001-01-16 Sankyo Co Ltd 肝障害の予防または抑制剤

Also Published As

Publication number Publication date
JP4722360B2 (ja) 2011-07-13
EP1278520A1 (en) 2003-01-29
JP2003527336A (ja) 2003-09-16
US6291480B1 (en) 2001-09-18
AU781552B2 (en) 2005-05-26
CA2390100C (en) 2010-01-05
CA2390100A1 (en) 2001-05-17
NZ518718A (en) 2004-03-26
ZA200203685B (en) 2003-06-05
EP1278520B1 (en) 2006-03-01
US6384052B1 (en) 2002-05-07
DE60026350T2 (de) 2006-11-09
DE60026350D1 (de) 2006-04-27
AU1590401A (en) 2001-06-06
WO2001034149A1 (en) 2001-05-17
ES2257336T3 (es) 2006-08-01
EP1278520A4 (en) 2003-05-02

Similar Documents

Publication Publication Date Title
DE60010098D1 (de) 28-epirapaloge
DE60032601D1 (de) Als antikrebsmittel verwendbare heterocyklische derivate
PT935465E (pt) Compostos novos de imidazole substituido
DE60019577D1 (de) 4, 5, 6, 7-tetrahydroindazolderivate als antitumormittel
NL300304I1 (nl) Pleuromutilinderivaten als anti-bacteriele middelen.
BR9706973A (pt) Novos compostos de imidazol substituídos
ATE384715T1 (de) 1,3 - disubstituierte pyrrolidine als alpha -2- adrenozeptorantagonisten
ATE294803T1 (de) Pyrrolobenzodiazepine
NO20002810L (no) Elektrokjemisk genereringsutstyr for oksygen
DE69930518D1 (de) Als antikrebsmittel verwendbare alkinyl-substituierte chinolin-2-on-derivate
ATE297898T1 (de) 4-carboxamino-2-subsitutierte-1,2,3,4- tetrahydrochinoline als cetp inhibitoren
ATE277906T1 (de) 4-carboxamino-2-methyl-1,2,3,4- tetrahydrochinoline als cetp inhibitoren
PT1140944E (pt) Derivados de epotilona e sua utilizacao como agentes antitumorais
ATE260914T1 (de) Triazolyltropanderivate als ccr5-modulatoren
NL300242I2 (nl) Omega-carboxyaryl gesubstitueerde difenylureums als raf kinaseremmers.
DE60025385D1 (de) 2,4-diaminopyrimidinderivate als immunosuppressiva
ATE228111T1 (de) M-amidinophenyl-analoga als faktor-xa-inhibitoren
NO991563L (no) N-substituerte, azaheterosykliske forbindelser
DE60020595D1 (de) 3,4-dihydro-(1h)chinazolin-2-on-verbindungen als csbp/p38-kinase-inhibitoren
PT998460E (pt) Novos derivados de tetrazole
ATE318600T1 (de) Diaryl piperidyl-pyrrol-derivate als antiprotozoenmittel
ATE387448T1 (de) 4,5-pyrazinoxindole als proteinkinasehemmer
IT1302004B1 (it) Tioeteri eterociclici come additivi per lubrificanti.
MXPA01010403A (es) Agentes quimiotacticos e inhibidores derivados de osteopontina y usos de los mismos.
DE69814894D1 (de) Isochinolin derivate als urokinase inhibitoren

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties