ATE318584T1 - Prozess zur herstellung kristalliner partikel von fluticason, beclomethason, salmeterol und salbutamol - Google Patents

Prozess zur herstellung kristalliner partikel von fluticason, beclomethason, salmeterol und salbutamol

Info

Publication number
ATE318584T1
ATE318584T1 AT02770107T AT02770107T ATE318584T1 AT E318584 T1 ATE318584 T1 AT E318584T1 AT 02770107 T AT02770107 T AT 02770107T AT 02770107 T AT02770107 T AT 02770107T AT E318584 T1 ATE318584 T1 AT E318584T1
Authority
AT
Austria
Prior art keywords
solvent
substance
liquid
crystalline particles
beclomethason
Prior art date
Application number
AT02770107T
Other languages
English (en)
Inventor
Martin John Mcloughlin
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Application granted granted Critical
Publication of ATE318584T1 publication Critical patent/ATE318584T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicinal Preparation (AREA)
  • Catalysts (AREA)
  • Saccharide Compounds (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
  • Mixers With Rotating Receptacles And Mixers With Vibration Mechanisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Extraction Or Liquid Replacement (AREA)
AT02770107T 2001-10-25 2002-10-23 Prozess zur herstellung kristalliner partikel von fluticason, beclomethason, salmeterol und salbutamol ATE318584T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB0125604.9A GB0125604D0 (en) 2001-10-25 2001-10-25 Novel process

Publications (1)

Publication Number Publication Date
ATE318584T1 true ATE318584T1 (de) 2006-03-15

Family

ID=9924497

Family Applications (1)

Application Number Title Priority Date Filing Date
AT02770107T ATE318584T1 (de) 2001-10-25 2002-10-23 Prozess zur herstellung kristalliner partikel von fluticason, beclomethason, salmeterol und salbutamol

Country Status (8)

Country Link
US (1) US20040258756A1 (de)
EP (1) EP1438023B1 (de)
JP (1) JP4351532B2 (de)
AT (1) ATE318584T1 (de)
DE (1) DE60209516T2 (de)
ES (1) ES2258156T3 (de)
GB (1) GB0125604D0 (de)
WO (1) WO2003035035A1 (de)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0216700D0 (en) 2002-07-18 2002-08-28 Astrazeneca Ab Process
GB0302673D0 (en) 2003-02-06 2003-03-12 Astrazeneca Ab Pharmaceutical formulations
SE0302029D0 (sv) * 2003-07-07 2003-07-07 Astrazeneca Ab Novel process
JP2005177746A (ja) * 2003-11-28 2005-07-07 Mitsubishi Chemicals Corp 有機化合物微粒子の製造方法
GB0406069D0 (en) * 2004-03-17 2004-04-21 Thompson James Process
CN101312713A (zh) * 2005-03-18 2008-11-26 纳米材料科技有限公司 可吸入的药物
JP4896418B2 (ja) * 2005-03-23 2012-03-14 富士フイルム株式会社 有機微粒子およびその分散液の製造方法、ならびにそれにより得られる有機微粒子およびその分散液
WO2006113309A1 (en) 2005-04-15 2006-10-26 Dr. Reddy's Laboratories Ltd. Lacidipine particles
JP4993875B2 (ja) * 2005-05-06 2012-08-08 富士フイルム株式会社 凝集ナノ粒子の分散方法
US8679341B2 (en) * 2005-05-06 2014-03-25 Fujifilm Corporation Method of concentrating nanoparticles and method of deaggregating aggregated nanoparticles
JP4870383B2 (ja) * 2005-05-06 2012-02-08 富士フイルム株式会社 ナノ粒子の濃縮方法
US8283395B2 (en) 2005-05-09 2012-10-09 Fujifilm Corporation Method of producing organic-particles-dispersion liquid
FR2897267A1 (fr) * 2006-02-16 2007-08-17 Flamel Technologies Sa Formes pharmaceutiques multimicroparticulaires pour administration per os
GB0705159D0 (en) * 2007-03-19 2007-04-25 Prosonix Ltd Process for making crystals
GB0711680D0 (en) * 2007-06-18 2007-07-25 Prosonix Ltd Process
US8052645B2 (en) 2008-07-23 2011-11-08 Avant Medical Corp. System and method for an injection using a syringe needle
EP2276527B1 (de) 2008-05-20 2018-02-28 Avant Medical Corp. Autoinjektorsystem
PT105058B (pt) * 2010-04-21 2013-04-17 Hovione Farmaciencia S A Processo para processamento de partículas de ingredientes activos farmacêuticos
CN102058996A (zh) * 2010-10-29 2011-05-18 华侨大学 非溶剂法改进超临界抗溶剂过程制备药物超细微粒的方法
CA2833748C (en) 2011-04-20 2019-07-16 Amgen Inc. Autoinjector apparatus
AU2012282936B2 (en) * 2011-07-08 2016-11-10 Pfizer Limited Process for the preparation of fluticasone propionate form 1
USD898908S1 (en) 2012-04-20 2020-10-13 Amgen Inc. Pharmaceutical product cassette for an injection device
US8765725B2 (en) 2012-05-08 2014-07-01 Aciex Therapeutics, Inc. Preparations of hydrophobic therapeutic agents, methods of manufacture and use thereof
CA2872845C (en) 2012-05-08 2021-11-09 Aciex Therapeutics, Inc. Preparation of nanocrystals of fluticasone propionate
EP2705838A1 (de) * 2012-09-06 2014-03-12 Xspray Microparticles Ab Tiotropium-Zubereitungen
DE102012221219B4 (de) * 2012-11-20 2014-05-28 Jesalis Pharma Gmbh Verfahren zur Vergrößerung der Partikelgröße kristalliner Wirkstoff-Mikropartikel
US9815865B2 (en) 2013-01-07 2017-11-14 Nicox Ophthalmics, Inc. Preparations of hydrophobic therapeutic agents, methods of manufacture and use thereof
WO2014137982A1 (en) 2013-03-08 2014-09-12 The Board Of Trustees Of The University Of Illinois Ultrasonic method and apparatus for producing particles having a controlled size distribution
JP6768501B2 (ja) 2013-03-15 2020-10-14 アムゲン・インコーポレーテッド 薬物カセット、自動注入機、および自動注入機システム
EP2968760B1 (de) 2013-03-15 2024-01-03 Amgen Inc. Medikamentenkassette, autoinjektor und autoinjektorsystem
CN104055741B (zh) * 2013-03-18 2017-02-15 青岛大学 一种孟鲁司特钠片剂及其制备方法
GB201402556D0 (en) 2014-02-13 2014-04-02 Crystec Ltd Improvements relating to inhalable particles
CN104771931B (zh) * 2015-04-20 2016-12-07 顾玉奎 一种中药超声提取装置

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4855436A (en) * 1987-12-11 1989-08-08 Jet Research Center, Inc. Method of preparation of 2,6-bis(picrylamino)-3,5-dinitropyridine
DE69112917T2 (de) * 1990-06-15 1996-05-15 Merck & Co Inc Kristallisationsverfahren zur Verbesserung der Kristallstruktur und -grösse.
FR2669635B1 (fr) * 1990-11-22 1994-06-10 Furchim Procede de fabrication d'hydroxymethylfurfural (hmf) du purete elevee.
US5658549A (en) * 1991-12-12 1997-08-19 Glaxo Group Limited Aerosol formulations containing propellant 134a and fluticasone propionate
GB9610821D0 (en) * 1996-05-23 1996-07-31 Glaxo Wellcome Inc Metering apparatus
GB9622173D0 (en) * 1996-10-24 1996-12-18 Glaxo Group Ltd Particulate Products
GB9828721D0 (en) * 1998-12-24 1999-02-17 Glaxo Group Ltd Novel apparatus and process
GB9925934D0 (en) * 1999-11-03 1999-12-29 Glaxo Group Ltd Novel apparatus and process

Also Published As

Publication number Publication date
WO2003035035A1 (en) 2003-05-01
ES2258156T3 (es) 2006-08-16
GB0125604D0 (en) 2001-12-19
US20040258756A1 (en) 2004-12-23
DE60209516T2 (de) 2006-08-10
JP2005512763A (ja) 2005-05-12
JP4351532B2 (ja) 2009-10-28
DE60209516D1 (de) 2006-04-27
EP1438023B1 (de) 2006-03-01
EP1438023A1 (de) 2004-07-21

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