ATE317839T1 - Verfahren zur fluormethylierung von alkoholen durch halogenierung-decarboxylierung - Google Patents

Verfahren zur fluormethylierung von alkoholen durch halogenierung-decarboxylierung

Info

Publication number
ATE317839T1
ATE317839T1 AT01935471T AT01935471T ATE317839T1 AT E317839 T1 ATE317839 T1 AT E317839T1 AT 01935471 T AT01935471 T AT 01935471T AT 01935471 T AT01935471 T AT 01935471T AT E317839 T1 ATE317839 T1 AT E317839T1
Authority
AT
Austria
Prior art keywords
fluoromethylation
decarboxylation
halogenation
alcohols
Prior art date
Application number
AT01935471T
Other languages
English (en)
Inventor
Christopher Bieniarz
Kornepati V Ramakrishna
Christopher Behme
Original Assignee
Abbott Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Lab filed Critical Abbott Lab
Application granted granted Critical
Publication of ATE317839T1 publication Critical patent/ATE317839T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C41/00—Preparation of ethers; Preparation of compounds having groups, groups or groups
    • C07C41/01—Preparation of ethers
    • C07C41/18—Preparation of ethers by reactions not forming ether-oxygen bonds
    • C07C41/22—Preparation of ethers by reactions not forming ether-oxygen bonds by introduction of halogens; by substitution of halogen atoms by other halogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
AT01935471T 2000-06-01 2001-05-14 Verfahren zur fluormethylierung von alkoholen durch halogenierung-decarboxylierung ATE317839T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US09/587,417 US6271422B1 (en) 2000-06-01 2000-06-01 Method for fluoromethylation of alcohols via halogenative decarboxylation

Publications (1)

Publication Number Publication Date
ATE317839T1 true ATE317839T1 (de) 2006-03-15

Family

ID=24349720

Family Applications (1)

Application Number Title Priority Date Filing Date
AT01935471T ATE317839T1 (de) 2000-06-01 2001-05-14 Verfahren zur fluormethylierung von alkoholen durch halogenierung-decarboxylierung

Country Status (29)

Country Link
US (1) US6271422B1 (de)
EP (1) EP1286939B1 (de)
JP (1) JP2004508293A (de)
KR (1) KR100799895B1 (de)
CN (1) CN1283606C (de)
AR (1) AR028664A1 (de)
AT (1) ATE317839T1 (de)
AU (2) AU2001261565B2 (de)
BG (1) BG107336A (de)
BR (1) BR0110776A (de)
CA (1) CA2410428A1 (de)
CZ (1) CZ20023790A3 (de)
DE (1) DE60117258T2 (de)
DK (1) DK1286939T3 (de)
ES (1) ES2258085T3 (de)
HK (1) HK1054371B (de)
HU (1) HUP0302239A3 (de)
IL (2) IL152857A0 (de)
MX (1) MXPA02011851A (de)
NO (1) NO20025791D0 (de)
NZ (1) NZ522502A (de)
PE (1) PE20011339A1 (de)
PL (1) PL364001A1 (de)
PT (1) PT1286939E (de)
SK (1) SK17512002A3 (de)
TW (1) TWI222435B (de)
UY (1) UY26738A1 (de)
WO (1) WO2001094286A1 (de)
ZA (1) ZA200208850B (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7083580B2 (en) 2001-04-06 2006-08-01 Mattioli Engineering Ltd. Method and apparatus for skin absorption enhancement and transdermal drug delivery
WO2005023175A2 (en) * 2003-09-10 2005-03-17 Cristália Produtos Químicos Farmacêuticos Ltda. Stable pharmaceutical composition of fluoroether compound for anesthetic use, method for stabilizing a fluoroether compound, use of stabilizer agent for precluding the degradation of a fluoroether compound
WO2006055748A2 (en) * 2004-11-17 2006-05-26 Minrad Inc. Method for the preparation of sevoflurane
CN103664584B (zh) * 2013-12-23 2015-06-03 湖南方盛制药股份有限公司 a-氟代丙酰乙酸酯的制备方法
CN104529721B (zh) * 2015-01-16 2017-04-19 河北一品制药有限公司 一种七氟烷的工业化制备方法
CN107698430B (zh) * 2017-11-01 2021-01-08 华东医药（西安）博华制药有限公司 一种七氟烷反应液的后处理方法

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1250928A (de) * 1968-10-28 1971-10-27
US3683092A (en) 1970-07-31 1972-08-08 Baxter Laboratories Inc Method of anesthesia
US4469898A (en) 1979-12-26 1984-09-04 Baxter Travenol Laboratories, Inc. Method of synthesizing fluoromethylhexafluoroisopropyl ether
US4250334A (en) 1979-12-26 1981-02-10 Baxter Travenol Laboratories, Inc. Method of synthesizing fluoromethylhexafluoroisopropyl ether
US4314087A (en) 1979-12-26 1982-02-02 Baxter Travenol Laboratories, Inc. Methods of synthesizing hexafluoroisopropanol from impure mixtures and synthesis of a fluoromethyl ether therefrom
JPS57209235A (en) * 1981-06-18 1982-12-22 Sumitomo Chem Co Ltd Tetrahydronaphthalene derivative and its preparation
US4847427A (en) * 1988-04-13 1989-07-11 E. I. Du Pont De Nemours And Company Process for preparing fluorocarbon polyethers
US4874901A (en) * 1988-05-06 1989-10-17 Boc, Inc. Process for the production of polyfluorinated ethers
US4996371A (en) * 1990-01-16 1991-02-26 Boc, Inc. Method for fluorodecarboxylation
CN1074759C (zh) * 1996-02-21 2001-11-14 森陶硝子株式会社 氟甲基1,1,1,3,3,3－六氟异丙醚的生产方法
US5789630A (en) 1996-02-27 1998-08-04 University Of Iowa Research Foundation Process for the synthesis of hexafluoropropanes
US5705710A (en) 1997-01-15 1998-01-06 University Of Iowa Research Foundation Process for the synthesis of hexafluoroisopropyl ethers
US5969193A (en) * 1997-08-18 1999-10-19 Medeva Pharmaceuticals Pa, Inc. Method for the preparation of sevoflurane
US5886239A (en) * 1997-11-21 1999-03-23 Baxter International Inc. Method of preparing monofluoromethyl ethers
US6100434A (en) * 1999-03-26 2000-08-08 Abbott Laboratories Method for synthesizing sevoflurane and an intermediate thereof
US6303831B1 (en) * 2000-06-01 2001-10-16 Abbott Laboratories Synthetic method for fluoromethylation of halogenated alcohols
US6245949B1 (en) * 2000-06-01 2001-06-12 Abbott Laboratories Synthetic method for the fluoromethylation of alcohols

Also Published As

Publication number Publication date
IL152857A (en) 2008-11-03
AU6156501A (en) 2001-12-17
WO2001094286A1 (en) 2001-12-13
KR20030007751A (ko) 2003-01-23
PT1286939E (pt) 2006-06-30
CN1446188A (zh) 2003-10-01
EP1286939B1 (de) 2006-02-15
PE20011339A1 (es) 2002-01-05
AR028664A1 (es) 2003-05-21
KR100799895B1 (ko) 2008-01-31
HUP0302239A2 (hu) 2003-10-28
DE60117258D1 (de) 2006-04-20
BR0110776A (pt) 2004-06-01
UY26738A1 (es) 2001-12-28
JP2004508293A (ja) 2004-03-18
PL364001A1 (en) 2004-11-29
CA2410428A1 (en) 2001-12-13
MXPA02011851A (es) 2003-05-14
CZ20023790A3 (cs) 2003-02-12
NZ522502A (en) 2004-09-24
ZA200208850B (en) 2003-12-22
DE60117258T2 (de) 2006-11-16
HUP0302239A3 (en) 2006-03-28
AU2001261565B2 (en) 2006-07-20
EP1286939A1 (de) 2003-03-05
CN1283606C (zh) 2006-11-08
HK1054371A1 (en) 2003-11-28
NO20025791L (no) 2002-12-02
IL152857A0 (en) 2003-06-24
NO20025791D0 (no) 2002-12-02
US6271422B1 (en) 2001-08-07
DK1286939T3 (da) 2006-06-19
HK1054371B (zh) 2006-12-08
TWI222435B (en) 2004-10-21
BG107336A (bg) 2003-07-31
SK17512002A3 (sk) 2003-04-01
ES2258085T3 (es) 2006-08-16

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