ATE317442T1 - Verfahren zur züchtung von mikroorganismen die methanol metabolisieren - Google Patents

Verfahren zur züchtung von mikroorganismen die methanol metabolisieren

Info

Publication number
ATE317442T1
ATE317442T1 AT97301428T AT97301428T ATE317442T1 AT E317442 T1 ATE317442 T1 AT E317442T1 AT 97301428 T AT97301428 T AT 97301428T AT 97301428 T AT97301428 T AT 97301428T AT E317442 T1 ATE317442 T1 AT E317442T1
Authority
AT
Austria
Prior art keywords
methanol
microorganisms
cultivation
rate
metabolize methanol
Prior art date
Application number
AT97301428T
Other languages
English (en)
Inventor
Koji Magota
Tomohiro Rogi
Yasuyoshi Sakai
Nobuo Kato
Original Assignee
Daiichi Asubio Pharma Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Daiichi Asubio Pharma Co Ltd filed Critical Daiichi Asubio Pharma Co Ltd
Application granted granted Critical
Publication of ATE317442T1 publication Critical patent/ATE317442T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/58—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from fungi
    • C12N9/60—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from fungi from yeast
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • C12N15/81—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
    • C12N15/815—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts for yeasts other than Saccharomyces

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Mycology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
AT97301428T 1996-03-04 1997-03-04 Verfahren zur züchtung von mikroorganismen die methanol metabolisieren ATE317442T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP07089996A JP3794748B2 (ja) 1996-03-04 1996-03-04 メタノール代謝系を有する微生物の培養法

Publications (1)

Publication Number Publication Date
ATE317442T1 true ATE317442T1 (de) 2006-02-15

Family

ID=13444848

Family Applications (1)

Application Number Title Priority Date Filing Date
AT97301428T ATE317442T1 (de) 1996-03-04 1997-03-04 Verfahren zur züchtung von mikroorganismen die methanol metabolisieren

Country Status (11)

Country Link
US (1) US6171828B1 (de)
EP (1) EP0794256B1 (de)
JP (1) JP3794748B2 (de)
CN (1) CN1205337C (de)
AT (1) ATE317442T1 (de)
AU (1) AU733585B2 (de)
CA (1) CA2198965C (de)
DE (1) DE69735224T2 (de)
DK (1) DK0794256T3 (de)
ES (1) ES2253767T3 (de)
TW (1) TW514666B (de)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2686899B1 (fr) * 1992-01-31 1995-09-01 Rhone Poulenc Rorer Sa Nouveaux polypeptides biologiquement actifs, leur preparation et compositions pharmaceutiques les contenant.
JP3794748B2 (ja) * 1996-03-04 2006-07-12 第一アスビオファーマ株式会社 メタノール代謝系を有する微生物の培養法
US20050100991A1 (en) * 2001-04-12 2005-05-12 Human Genome Sciences, Inc. Albumin fusion proteins
JP2003530838A (ja) * 2000-04-12 2003-10-21 ヒューマン ゲノム サイエンシズ インコーポレイテッド アルブミン融合タンパク質
CA2446739A1 (en) * 2001-05-25 2002-12-05 Human Genome Sciences, Inc. Chemokine beta-1 fusion proteins
ES2425738T3 (es) * 2001-12-21 2013-10-17 Human Genome Sciences, Inc. Proteínas de fusión de la albúmina
AU2002364587A1 (en) * 2001-12-21 2003-07-30 Human Genome Sciences, Inc. Albumin fusion proteins
EP1594530A4 (de) 2003-01-22 2006-10-11 Human Genome Sciences Inc Albuminfusionsproteine
ATE550437T1 (de) * 2003-08-01 2012-04-15 Us Gov Health & Human Serv Verfahren zur expression und reinigung von immunotoxinen
WO2014071289A1 (en) 2012-11-05 2014-05-08 Genomatica, Inc. Microorganisms for enhancing the availability of reducing equivalents in the presence of methanol, and for producing 3-hydroxyisobutyrate
CN103060411B (zh) * 2013-01-05 2014-02-05 义马煤业集团煤生化高科技工程有限公司 一种甲醇蛋白肽的生产方法
CN103045494B (zh) * 2013-01-05 2014-10-29 义马煤业集团煤生化高科技工程有限公司 一株高效转化甲醇生产单细胞蛋白的毕赤酵母及其应用
EP3184642B1 (de) * 2015-12-22 2019-05-08 bisy e.U. Hefezelle
CN119095864A (zh) * 2022-04-02 2024-12-06 武汉远大弘元股份有限公司 一种甲醇诱导启动子及其在制备丙谷二肽中的应用
WO2025077804A1 (en) * 2023-10-12 2025-04-17 Chengdu Kanghua Biological Products Co., Ltd. Methanol monitoring method for the fermentation process of methanotrophic yeast
CN120015152B (zh) * 2025-04-21 2025-08-12 苏州工业园区旭太生物工程有限公司 一种多肽诱导型生物发酵培养基优化方法及系统

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4342832A (en) * 1979-07-05 1982-08-03 Genentech, Inc. Method of constructing a replicable cloning vehicle having quasi-synthetic genes
JPH0427384A (ja) * 1990-05-21 1992-01-30 Central Glass Co Ltd 蟻酸脱水素酵素の製造法
US5612198A (en) * 1990-09-04 1997-03-18 The Salk Institute Production of insulin-like growth factor-1 in methylotrophic yeast cells
WO1992013951A1 (en) * 1991-02-04 1992-08-20 The Salk Institute Biotechnology/Industrial Associates, Inc. Production of human serum albumin in methylotrophic yeast cells
CA2058820C (en) * 1991-04-25 2003-07-15 Kotikanyad Sreekrishna Expression cassettes and vectors for the secretion of human serum albumin in pichia pastoris cells
ES2093294T3 (es) * 1992-02-28 1996-12-16 Suntory Ltd Nuevo vector que comprende un promotor inducible por el metanol y/o glicerol.
GB9402832D0 (en) * 1994-02-15 1994-04-06 Smith Kline Beecham Biolog S A Novel process
JP3794748B2 (ja) * 1996-03-04 2006-07-12 第一アスビオファーマ株式会社 メタノール代謝系を有する微生物の培養法

Also Published As

Publication number Publication date
DE69735224T2 (de) 2006-08-03
US6171828B1 (en) 2001-01-09
AU1503897A (en) 1997-09-11
CN1205337C (zh) 2005-06-08
JP3794748B2 (ja) 2006-07-12
EP0794256B1 (de) 2006-02-08
CA2198965A1 (en) 1997-09-04
AU733585B2 (en) 2001-05-17
DE69735224D1 (de) 2006-04-20
DK0794256T3 (da) 2006-06-12
CA2198965C (en) 2007-05-15
EP0794256A2 (de) 1997-09-10
ES2253767T3 (es) 2006-06-01
JPH09234059A (ja) 1997-09-09
TW514666B (en) 2002-12-21
CN1167152A (zh) 1997-12-10
EP0794256A3 (de) 1998-06-17

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