ATE316989T1 - Synthetische melanine auf pflanzenbasis, verfahren zu deren herstellung sowie diese enthaltende zusammensetzungen - Google Patents
Synthetische melanine auf pflanzenbasis, verfahren zu deren herstellung sowie diese enthaltende zusammensetzungenInfo
- Publication number
- ATE316989T1 ATE316989T1 AT00954851T AT00954851T ATE316989T1 AT E316989 T1 ATE316989 T1 AT E316989T1 AT 00954851 T AT00954851 T AT 00954851T AT 00954851 T AT00954851 T AT 00954851T AT E316989 T1 ATE316989 T1 AT E316989T1
- Authority
- AT
- Austria
- Prior art keywords
- production
- plant
- compositions containing
- based synthetic
- containing same
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
- A61Q17/04—Topical preparations for affording protection against sunlight or other radiation; Topical sun tanning preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
- A61K8/347—Phenols
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/36—Carboxylic acids; Salts or anhydrides thereof
- A61K8/368—Carboxylic acids; Salts or anhydrides thereof with carboxyl groups directly bound to carbon atoms of aromatic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/44—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/4906—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom
- A61K8/4913—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom having five membered rings, e.g. pyrrolidone carboxylic acid
- A61K8/492—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom having five membered rings, e.g. pyrrolidone carboxylic acid having condensed rings, e.g. indol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/4973—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom
- A61K8/498—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom having 6-membered rings or their condensed derivatives, e.g. coumarin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/60—Sugars; Derivatives thereof
- A61K8/602—Glycosides, e.g. rutin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/84—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
- A61K8/86—Polyethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9728—Fungi, e.g. yeasts
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9789—Magnoliopsida [dicotyledons]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q1/00—Make-up preparations; Body powders; Preparations for removing make-up
- A61Q1/02—Preparations containing skin colorants, e.g. pigments
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/04—Preparations for care of the skin for chemically tanning the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q5/00—Preparations for care of the hair
- A61Q5/10—Preparations for permanently dyeing the hair
-
- C—CHEMISTRY; METALLURGY
- C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
- C09B—ORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES, e.g. PIGMENTS; MORDANTS; LAKES
- C09B61/00—Dyes of natural origin prepared from natural sources, e.g. vegetable sources
-
- C—CHEMISTRY; METALLURGY
- C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
- C09B—ORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES, e.g. PIGMENTS; MORDANTS; LAKES
- C09B69/00—Dyes not provided for by a single group of this subclass
- C09B69/10—Polymeric dyes; Reaction products of dyes with monomers or with macromolecular compounds
- C09B69/104—Polymeric dyes; Reaction products of dyes with monomers or with macromolecular compounds containing an indole dye, including melanine derivates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/42—Colour properties
- A61K2800/43—Pigments; Dyes
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT1999MI001896A ITMI991896A1 (it) | 1999-09-09 | 1999-09-09 | Melanine e pigmenti vegetali |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE316989T1 true ATE316989T1 (de) | 2006-02-15 |
Family
ID=11383593
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT00954851T ATE316989T1 (de) | 1999-09-09 | 2000-09-08 | Synthetische melanine auf pflanzenbasis, verfahren zu deren herstellung sowie diese enthaltende zusammensetzungen |
Country Status (9)
Country | Link |
---|---|
EP (1) | EP1212376B1 (de) |
JP (1) | JP2003509529A (de) |
AT (1) | ATE316989T1 (de) |
AU (1) | AU6720200A (de) |
BR (1) | BR0014257A (de) |
CA (1) | CA2383932A1 (de) |
DE (1) | DE60025833D1 (de) |
IT (1) | ITMI991896A1 (de) |
WO (1) | WO2001018125A1 (de) |
Families Citing this family (42)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU2001269301A1 (en) * | 2000-07-21 | 2002-02-05 | Zylepsis Limited | Melanin compositions |
GR20020100011A (el) * | 2002-01-16 | 2003-09-24 | Νικολαος Αβραμιδης | Η μελανινη για χρηση στην προληψη ή θεραπεια καθε τυπου υπερχοληστερολαιμιας, υπερλιπιδαιμιας και καθε διαταραχη λιπιδιων, σε ανθρωπους και ζωα |
AU2003237800A1 (en) | 2002-04-05 | 2003-10-27 | Government Of The United States, As Represented Bythe Secretary Of The Army | Polymeric antioxidants |
FR2851916B1 (fr) * | 2003-03-05 | 2007-04-27 | Utilisation de polyphenols catechiques pour la preparation de compositions destinees a favoriser la pigmentation naturelles de la peau | |
WO2004080380A2 (fr) * | 2003-03-05 | 2004-09-23 | L'oreal | Utilisation de polyphenols catechniques pour la preparation de compositions destinees a favoriser la pigmentation naturelle de la peau |
FR2873025B1 (fr) * | 2004-07-13 | 2008-02-29 | Oreal | Procede de traitement cosmetique pour moduler la pigmentation de la peau ou des phaneres |
US20060041087A1 (en) | 2004-07-23 | 2006-02-23 | Cholli Ashok L | Anti-oxidant macromonomers and polymers and methods of making and using the same |
JP4659407B2 (ja) * | 2004-07-29 | 2011-03-30 | サントリーホールディングス株式会社 | オリゴメリックプロアントシアニジン(opc)の分析方法 |
JP2006076946A (ja) * | 2004-09-10 | 2006-03-23 | Hoyu Co Ltd | 重金属及び/又は放射性物質の排泄、又は除去を用途とするメラニン類含有組成物、及びメラニン類の用途 |
CA2589883A1 (en) | 2004-12-03 | 2006-06-08 | Polnox Corporation | Synthesis of aniline and phenol-based antioxidant macromonomers and corresponding polymers |
WO2006060801A2 (en) | 2004-12-03 | 2006-06-08 | Polnox Corporation | Process for the synthesis of polyalkylphenol antioxidants |
FR2881953A1 (fr) * | 2005-02-11 | 2006-08-18 | Greenpharma Sa Sa | Utilisation de derives de la taxifoline comme agents pigmentants et protecteurs de la peau ou des cheveux |
EP1861484A2 (de) | 2005-02-22 | 2007-12-05 | Polnox Corporation | Stickstoff und gehindertes phenol enthaltende doppelfunktionelle makromolekulare antioxidantien: synthese, leistungsfähigkeit und anwendungen |
WO2006104957A2 (en) | 2005-03-25 | 2006-10-05 | Polnox Corporation | Alkylated and polymeric macromolecular antioxidants and methods of making and using the same |
WO2006116532A2 (en) * | 2005-04-28 | 2006-11-02 | University Of Massachusetts Lowell | Synthesis of oligo/poly(catechins) and methods of use |
WO2007050985A2 (en) | 2005-10-27 | 2007-05-03 | Polnox Corporation | Macromolecular antioxidants based on stξrically hindered phenolic phosphites |
US20070149660A1 (en) | 2005-10-27 | 2007-06-28 | Vijayendra Kumar | Stabilized polyolefin compositions |
US20070161522A1 (en) | 2005-12-02 | 2007-07-12 | Cholli Ashok L | Lubricant oil compositions |
GB2433439A (en) * | 2005-12-21 | 2007-06-27 | Ciba Sc Holding Ag | Use of transmission dyes to protect human skin from UV radiation |
WO2008005358A2 (en) | 2006-07-06 | 2008-01-10 | Polnox Corporation | Novel macromolecular antioxidants comprising differing antioxidant moieties: structures, methods of making and using the same |
US7767853B2 (en) | 2006-10-20 | 2010-08-03 | Polnox Corporation | Antioxidants and methods of making and using the same |
JP5201662B2 (ja) * | 2007-02-28 | 2013-06-05 | キッコーマン株式会社 | 血流改善組成物 |
FR2914859B1 (fr) * | 2007-04-13 | 2012-09-07 | Lucas Meyer Cosmetics | Compositions cosmetiques stables. |
JP5750730B2 (ja) | 2008-07-28 | 2015-07-22 | 株式会社えがお | ゴマ種子由来色素 |
FR2944794B1 (fr) * | 2009-04-28 | 2012-06-29 | Rocher Yves Biolog Vegetale | Procede de preparation d'oligomeres de glycoside de flavonoide et utilisation en cosmetique. |
CN102666671B (zh) * | 2009-10-23 | 2014-06-11 | 首尔大学校产学协力团 | 纳米尺寸的黑色素颗粒及其制备方法 |
CN103534009B (zh) * | 2011-05-16 | 2016-08-31 | 先进水处理公司 | 具有聚多巴胺涂层的改进的膜 |
CN103304801A (zh) * | 2012-03-14 | 2013-09-18 | 云南天士力帝泊洱生物茶集团有限公司 | 一种茶褐素的制备方法 |
KR101729710B1 (ko) | 2012-04-09 | 2017-04-24 | 서울대학교산학협력단 | 물에 안정하게 분산되는 멜라닌 나노입자를 포함하는 핵자기 공명 영상 조영제 |
EP3071544B1 (de) | 2013-11-22 | 2022-07-06 | Polnox Corporation | Makromolekulare antioxidanzien auf basis eines doppeltyp-anteils pro molekül: strukturen, verfahren zur herstellung und verwendung davon |
JP6411733B2 (ja) * | 2013-12-09 | 2018-10-24 | 株式会社ピュール | 噴霧容器入りヘアカラーリング剤 |
EP3082729A1 (de) * | 2013-12-20 | 2016-10-26 | Unilever N.V. | Sonnenlose selbstbräunung |
JP6562469B2 (ja) * | 2016-05-13 | 2019-08-21 | 株式会社Nil | 毛髪色素増強剤 |
WO2017195841A1 (ja) * | 2016-05-13 | 2017-11-16 | 株式会社Nil | 毛髪色素増強剤 |
JP6716130B2 (ja) * | 2016-07-04 | 2020-07-01 | 学校法人中部大学 | 抗アレルギー剤 |
US20180251695A1 (en) | 2017-03-01 | 2018-09-06 | Polnox Corporation | Macromolecular Corrosion (McIn) Inhibitors: Structures, Methods Of Making And Using The Same |
CN109260071B (zh) * | 2018-09-17 | 2021-06-15 | 西安理工大学 | 一种全天然酶发酵黑色染发剂的制备方法 |
CN111529434B (zh) * | 2020-05-11 | 2021-09-03 | 山东农业大学 | 一种含egcg的唇部预防保健产品及其应用 |
CN113081884B (zh) * | 2021-04-26 | 2022-05-24 | 北京中医药大学 | 一种抗黑色素组合物、制备方法及应用 |
CN113576972B (zh) * | 2021-08-11 | 2023-05-26 | 昆明医科大学 | 一种以滇橄榄鲜果果肉为主原料的美白淡斑复方制剂及其制备方法 |
CN115058005B (zh) * | 2022-05-11 | 2023-06-13 | 四川大学 | 低介电损耗的黑色素纳米材料及在基板上制备其涂层的方法及产品 |
KR102551315B1 (ko) * | 2022-08-02 | 2023-07-04 | 주식회사 미피션 | 하이드록시티로솔을 포함하는 모발 염색용 조성물 |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5714517A (en) * | 1980-06-27 | 1982-01-25 | Sansho Seiyaku Kk | Whitening cosmetic |
CA2000114C (en) * | 1988-10-03 | 1995-06-20 | Laurence K. Grill | Melanin production |
JP2823891B2 (ja) * | 1989-08-19 | 1998-11-11 | 琳次郎 猿野 | 毛髪用組成物の製造方法 |
US5227459A (en) * | 1990-05-18 | 1993-07-13 | Yale University | Synthetic melanin |
JPH06500011A (ja) * | 1990-06-29 | 1994-01-06 | ラージ スケール バイオロジー コーポレイション | 形質転換された微生物によるメラニンの製造 |
US5122461A (en) * | 1990-11-19 | 1992-06-16 | Industrial Technology Research Institute | Preparation of pyrocatecholic compounds |
IT1255146B (it) * | 1992-05-08 | 1995-10-20 | Intercast Europ | Melanina sintetica purificata particolarmente per dispositivi ottici abassa diffusione |
US5340734A (en) * | 1992-11-25 | 1994-08-23 | Biosource Genetics Corporation | Method for making stable, extracellular tyrosinase and synthesis of polyphenolic polymers therefrom |
FR2704554B1 (fr) * | 1993-04-27 | 1995-07-13 | Oreal | Procede de preparation d'un pigment melanique de faible granulometrie et son utilisation en cosmetique. |
US5744125A (en) * | 1993-08-19 | 1998-04-28 | Yale University | Cosmetic melanins |
US6242415B1 (en) * | 1997-02-12 | 2001-06-05 | Sri International | Mediation of cytokines by melanin |
DE19717837C2 (de) * | 1997-04-26 | 1999-10-28 | Thomas Feuerstein | HPLC-Säule zur Untersuchung der Melaninaffinität von Substanzen |
-
1999
- 1999-09-09 IT IT1999MI001896A patent/ITMI991896A1/it unknown
-
2000
- 2000-09-08 JP JP2001522340A patent/JP2003509529A/ja active Pending
- 2000-09-08 WO PCT/IB2000/001276 patent/WO2001018125A1/en active IP Right Grant
- 2000-09-08 AU AU67202/00A patent/AU6720200A/en not_active Abandoned
- 2000-09-08 BR BR0014257-3A patent/BR0014257A/pt not_active Application Discontinuation
- 2000-09-08 DE DE60025833T patent/DE60025833D1/de not_active Expired - Lifetime
- 2000-09-08 AT AT00954851T patent/ATE316989T1/de not_active IP Right Cessation
- 2000-09-08 EP EP00954851A patent/EP1212376B1/de not_active Expired - Lifetime
- 2000-09-08 CA CA002383932A patent/CA2383932A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
BR0014257A (pt) | 2002-05-21 |
ITMI991896A1 (it) | 2001-03-09 |
EP1212376A1 (de) | 2002-06-12 |
DE60025833D1 (de) | 2006-04-13 |
EP1212376B1 (de) | 2006-02-01 |
WO2001018125A1 (en) | 2001-03-15 |
CA2383932A1 (en) | 2001-03-15 |
ITMI991896A0 (it) | 1999-09-09 |
AU6720200A (en) | 2001-04-10 |
JP2003509529A (ja) | 2003-03-11 |
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