ATE314369T1 - Dibenzo a,g) quinolizinium derivate und ihre salze - Google Patents

Dibenzo a,g) quinolizinium derivate und ihre salze

Info

Publication number
ATE314369T1
ATE314369T1 AT99901239T AT99901239T ATE314369T1 AT E314369 T1 ATE314369 T1 AT E314369T1 AT 99901239 T AT99901239 T AT 99901239T AT 99901239 T AT99901239 T AT 99901239T AT E314369 T1 ATE314369 T1 AT E314369T1
Authority
AT
Austria
Prior art keywords
group
carbons
represent
formula
different
Prior art date
Application number
AT99901239T
Other languages
English (en)
Inventor
Jung Ho Hanwool Apt - Kim
Tae Neung Jhong
Young Ki Keosung Apt - Paik
Joon Seo Durae Apt - Park
Eui Deok Durae Apt - Kim
You Suk Hyundae Apt Nd Lee
Seung Un Durae Apt - Kim
Original Assignee
Hanwha Chemical Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hanwha Chemical Corp filed Critical Hanwha Chemical Corp
Application granted granted Critical
Publication of ATE314369T1 publication Critical patent/ATE314369T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Quinoline Compounds (AREA)
AT99901239T 1998-12-21 1999-01-19 Dibenzo a,g) quinolizinium derivate und ihre salze ATE314369T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR1019980058722A KR20000042507A (ko) 1998-12-21 1998-12-21 콜레스테롤 생합성 저해효과를 나타내는 디벤조[a,g]퀴놀리지늄 유도체
PCT/KR1999/000030 WO2000037468A1 (en) 1998-12-21 1999-01-19 DIBENZO[a,g]QUINOLIZINIUM DERIVATIVES AND THE SALTS THEREOF

Publications (1)

Publication Number Publication Date
ATE314369T1 true ATE314369T1 (de) 2006-01-15

Family

ID=36676726

Family Applications (1)

Application Number Title Priority Date Filing Date
AT99901239T ATE314369T1 (de) 1998-12-21 1999-01-19 Dibenzo a,g) quinolizinium derivate und ihre salze

Country Status (14)

Country Link
US (2) US6030979A (de)
EP (1) EP1140930B1 (de)
JP (1) JP2000191662A (de)
KR (1) KR20000042507A (de)
CN (1) CN1216884C (de)
AT (1) ATE314369T1 (de)
AU (1) AU777377B2 (de)
BR (1) BR9916431A (de)
CA (1) CA2355469A1 (de)
DE (1) DE69929244T2 (de)
ES (1) ES2257027T3 (de)
IL (1) IL143754A0 (de)
RU (1) RU2223962C2 (de)
WO (1) WO2000037468A1 (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20000021073A (ko) 1998-09-25 2000-04-15 박원배 콜레스테롤 생합성 저해제
CN1759834B (zh) * 2004-09-17 2010-06-23 中国医学科学院医药生物技术研究所 黄连素或其与辛伐他汀联合在制备用于预防或治疗与血脂有关疾病或症状的产品中用途
KR100706309B1 (ko) * 2006-02-14 2007-04-12 한국생명공학연구원 항진균 활성이 우수한 베르베루빈 유도체
CN101153039B (zh) * 2006-09-30 2010-12-01 中国科学院上海药物研究所 13，13a-二氢小檗碱衍生物及其药物组合物和用途
US8003795B2 (en) 2007-06-22 2011-08-23 Cvi Pharmaceuticals Limited Compounds and compositions for reducing lipid levels
WO2009035598A1 (en) * 2007-09-10 2009-03-19 Concert Pharmaceuticals, Inc. Deuterated pirfenidone
WO2010075469A1 (en) * 2008-12-23 2010-07-01 Cvi Pharmaceuticals Limited Corydaline derivatives useful for reducing lipid levels
US20110009628A1 (en) * 2009-07-08 2011-01-13 Haiyan Liu Compounds and Compositions for Modulating Lipid Levels and Methods of Preparing Same
KR101155753B1 (ko) 2010-09-29 2012-06-12 동아제약주식회사 퀴놀린 유도체 화합물을 포함하는 약학 조성물
CA2970561C (en) * 2015-01-07 2019-07-23 Changzhou Deze Medical Science Co., Ltd Mangiferin-6-o-berberine salt and preparation method and use thereof
WO2018022904A2 (en) 2016-07-27 2018-02-01 Case Western Reserve University Compounds and methods of promoting myelination
CN107722000A (zh) * 2017-11-03 2018-02-23 中国药科大学 9位－取代的小檗碱衍生物的制备及其医药用途

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1265627A (de) * 1970-08-26 1972-03-01
DE2043218A1 (de) * 1970-09-01 1972-03-02 Dainippon Pharmaceutical Co , Ltd, Osaka (Japan) Pharmazeutische Zubereitungen zur Behandlung von Magengeschwüren
JPS4942700A (de) * 1972-08-25 1974-04-22
JPS4972298A (de) * 1972-11-16 1974-07-12
US3835140A (en) * 1973-01-30 1974-09-10 Us Health Process for the preparation of dehydroberbinium salts
JPS5231360B2 (de) * 1973-05-11 1977-08-13
US4042592A (en) * 1974-05-08 1977-08-16 Kanebo, Ltd. Novel dibenzo[a,g]quinolizinium compounds
DE2527941A1 (de) * 1975-06-23 1977-01-20 Kanebo Ltd Neue berbinderivate, verfahren zu ihrer herstellung und sie enthaltende mittel
US4033966A (en) * 1975-06-24 1977-07-05 Kanebo, Ltd. Novel berbine derivatives
JPS5248696A (en) * 1975-10-14 1977-04-18 Tetsuo Ikegawa Preparation of 9-substituted-tetrahdropyranyl berberines
US4200629A (en) * 1975-11-26 1980-04-29 Junichi Nakamura Anti-fungal substance and preparing method thereof
US4087426A (en) * 1976-08-16 1978-05-02 Research Corporation Oxybisberberine and a process for its production
US4980344A (en) * 1982-05-14 1990-12-25 Maroko Peter R Compositions for improving circulatory performance
US4761417A (en) * 1982-05-14 1988-08-02 Maroko Peter R Compounds, compositions and method of treatments for improving circulatory performance
JPS61130289A (ja) * 1984-11-29 1986-06-18 Ss Pharmaceut Co Ltd １３−プロピルベルベリンの塩
JPH0814787B2 (ja) * 1987-07-15 1996-02-14 三菱電機株式会社 デ−タ伝送装置
EP0307489A1 (de) * 1987-09-15 1989-03-22 S O "Pharmachim" Antiglaukommittel

Also Published As

Publication number Publication date
US6030979A (en) 2000-02-29
DE69929244T2 (de) 2006-09-14
CN1216884C (zh) 2005-08-31
AU777377B2 (en) 2004-10-14
KR20000042507A (ko) 2000-07-15
DE69929244D1 (de) 2006-02-02
ES2257027T3 (es) 2006-07-16
EP1140930B1 (de) 2005-12-28
EP1140930A1 (de) 2001-10-10
US6028197A (en) 2000-02-22
IL143754A0 (en) 2002-04-21
AU2077699A (en) 2000-07-12
WO2000037468A1 (en) 2000-06-29
BR9916431A (pt) 2001-09-04
RU2223962C2 (ru) 2004-02-20
CN1330650A (zh) 2002-01-09
JP2000191662A (ja) 2000-07-11
CA2355469A1 (en) 2000-06-29

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