ATE308518T1 - Indolderivate und deren verwendung als liganden der receptoren cb2 - Google Patents

Indolderivate und deren verwendung als liganden der receptoren cb2

Info

Publication number
ATE308518T1
ATE308518T1 AT03752808T AT03752808T ATE308518T1 AT E308518 T1 ATE308518 T1 AT E308518T1 AT 03752808 T AT03752808 T AT 03752808T AT 03752808 T AT03752808 T AT 03752808T AT E308518 T1 ATE308518 T1 AT E308518T1
Authority
AT
Austria
Prior art keywords
indole derivatives
ligands
receptors
halo
so2nr5r6
Prior art date
Application number
AT03752808T
Other languages
English (en)
Inventor
Francis Barth
Carole Guillaumont
Murielle Rinaldi-Carmona
Claude Vernhet
Original Assignee
Sanofi Aventis
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Aventis filed Critical Sanofi Aventis
Application granted granted Critical
Publication of ATE308518T1 publication Critical patent/ATE308518T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/12—Antidiarrhoeals
    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/02—Nasal agents, e.g. decongestants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A—HUMAN NECESSITIES
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    • A—HUMAN NECESSITIES
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    • A—HUMAN NECESSITIES
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    • A—HUMAN NECESSITIES
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    • A61P19/00—Drugs for skeletal disorders
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    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
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    • A—HUMAN NECESSITIES
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    • A—HUMAN NECESSITIES
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    • A—HUMAN NECESSITIES
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    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
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    • A—HUMAN NECESSITIES
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    • A61P25/00—Drugs for disorders of the nervous system
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    • A—HUMAN NECESSITIES
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    • A—HUMAN NECESSITIES
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    • A—HUMAN NECESSITIES
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    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Diabetes (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Psychiatry (AREA)
  • Cardiology (AREA)
  • Oncology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Hematology (AREA)
  • Dermatology (AREA)
  • Urology & Nephrology (AREA)
  • Hospice & Palliative Care (AREA)
  • Obesity (AREA)
  • Psychology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Otolaryngology (AREA)
AT03752808T 2002-05-17 2003-05-15 Indolderivate und deren verwendung als liganden der receptoren cb2 ATE308518T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0206133A FR2839718B1 (fr) 2002-05-17 2002-05-17 Derives d'indole, leur procede de preparation et les compositions pharmaceutiques en contenant
PCT/FR2003/001470 WO2003097597A2 (fr) 2002-05-17 2003-05-15 Derives d'indole et leur utilisation en tant que ligands des recepteurs cb2

Publications (1)

Publication Number Publication Date
ATE308518T1 true ATE308518T1 (de) 2005-11-15

Family

ID=29286599

Family Applications (1)

Application Number Title Priority Date Filing Date
AT03752808T ATE308518T1 (de) 2002-05-17 2003-05-15 Indolderivate und deren verwendung als liganden der receptoren cb2

Country Status (20)

Country Link
US (1) US7138424B2 (de)
EP (1) EP1507758B1 (de)
JP (1) JP2005530797A (de)
KR (1) KR20040106560A (de)
CN (1) CN1668588A (de)
AT (1) ATE308518T1 (de)
AU (1) AU2003258762A1 (de)
BR (1) BR0311185A (de)
CA (1) CA2482756A1 (de)
DE (1) DE60302156T2 (de)
EA (1) EA200401315A1 (de)
FR (1) FR2839718B1 (de)
HR (1) HRP20041073A2 (de)
IL (1) IL164941A0 (de)
IS (1) IS7513A (de)
MA (1) MA27203A1 (de)
MX (1) MXPA04011387A (de)
NO (1) NO20044970L (de)
PL (1) PL374111A1 (de)
WO (1) WO2003097597A2 (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7067539B2 (en) * 2001-02-08 2006-06-27 Schering Corporation Cannabinoid receptor ligands
UY27939A1 (es) 2002-08-21 2004-03-31 Glaxo Group Ltd Compuestos
AR043633A1 (es) 2003-03-20 2005-08-03 Schering Corp Ligandos de receptores de canabinoides
GB0402355D0 (en) * 2004-02-03 2004-03-10 Glaxo Group Ltd Novel compounds
TW200533657A (en) * 2004-02-17 2005-10-16 Esteve Labor Dr Substituted pyrazoline compounds, their preparation and use as medicaments
MX2007006102A (es) * 2004-11-22 2007-07-11 Threshold Pharmaceuticals Inc Agentes anti-cancer de union a tubulina y profarmacos de los mismos.
EP1743892A1 (de) * 2005-07-15 2007-01-17 Laboratorios del Dr. Esteve S.A. Substituierte Pyrazolin Verbindungen, deren Herstellung und Verwendung als Medikament
FR2893615B1 (fr) 2005-11-18 2008-03-07 Sanofi Aventis Sa Derives de 3-acylindole, leur preparation et leur application en therapeutique
GB0702862D0 (en) * 2007-02-14 2007-03-28 Univ Aberdeen Therapeutic compounds
RU2010111551A (ru) * 2007-08-29 2011-10-10 Шеринг Корпорейшн (US) Замещенные индольные производные и способы их применения
FR2933697B1 (fr) 2008-07-11 2010-08-13 Sanofi Aventis Derives de 1-benzyl-cinnolin-4-(1h)-one substitues, leur preparation et leur application en therapeutique
FR2950055A1 (fr) 2009-09-17 2011-03-18 Sanofi Aventis Derives de 3-amino-cinnolin-4(1h)-one substitues, leur preparation et leur application en therapeutique
FR2983859B1 (fr) 2011-12-12 2014-01-17 Sanofi Sa Derives de 1,3,5-triazine-2-amine, leur preparation et leur application en diagnostique et en therapeutique

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2735774B1 (fr) * 1995-06-21 1997-09-12 Sanofi Sa Utilisation de composes agonistes du recepteur cb2 humain pour la preparation de medicaments immunomodulateurs, nouveaux composes agonistes du recepteur cb2 et les compositions pharmaceutiques les contenant
CA2387138A1 (en) * 1999-10-18 2001-04-26 University Of Connecticut Cannabimimetic indole derivatives

Also Published As

Publication number Publication date
US20060089345A1 (en) 2006-04-27
DE60302156T2 (de) 2006-07-20
CN1668588A (zh) 2005-09-14
IL164941A0 (en) 2005-12-18
BR0311185A (pt) 2005-02-22
US7138424B2 (en) 2006-11-21
JP2005530797A (ja) 2005-10-13
MXPA04011387A (es) 2005-02-14
CA2482756A1 (fr) 2003-11-27
MA27203A1 (fr) 2005-01-03
FR2839718A1 (fr) 2003-11-21
EP1507758B1 (de) 2005-11-02
DE60302156D1 (de) 2005-12-08
FR2839718B1 (fr) 2004-06-25
KR20040106560A (ko) 2004-12-17
AU2003258762A1 (en) 2003-12-02
WO2003097597A3 (fr) 2004-04-01
WO2003097597A2 (fr) 2003-11-27
IS7513A (is) 2004-10-20
NO20044970L (no) 2005-02-17
EA200401315A1 (ru) 2005-04-28
PL374111A1 (en) 2005-10-03
HRP20041073A2 (en) 2004-12-31
EP1507758A2 (de) 2005-02-23

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