BR0311185A - Derivados de indol, seu processo de preparação e composições farmacêuticas contendo os mesmos - Google Patents

Derivados de indol, seu processo de preparação e composições farmacêuticas contendo os mesmos

Info

Publication number
BR0311185A
BR0311185A BR0311185-7A BR0311185A BR0311185A BR 0311185 A BR0311185 A BR 0311185A BR 0311185 A BR0311185 A BR 0311185A BR 0311185 A BR0311185 A BR 0311185A
Authority
BR
Brazil
Prior art keywords
indole derivatives
pharmaceutical compositions
preparation process
compositions containing
halo
Prior art date
Application number
BR0311185-7A
Other languages
English (en)
Inventor
Francis Barth
Carole Guillaumont
Murielle Rinaldi-Carmona
Claude Vernhet
Original Assignee
Sanofi Aventis
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Aventis filed Critical Sanofi Aventis
Publication of BR0311185A publication Critical patent/BR0311185A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/12—Antidiarrhoeals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
    • A—HUMAN NECESSITIES
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/02—Nasal agents, e.g. decongestants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A—HUMAN NECESSITIES
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    • A—HUMAN NECESSITIES
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    • A61P19/00—Drugs for skeletal disorders
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/06—Antigout agents, e.g. antihyperuricemic or uricosuric agents
    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P19/00—Drugs for skeletal disorders
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    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
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    • A—HUMAN NECESSITIES
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    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
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    • A—HUMAN NECESSITIES
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    • A—HUMAN NECESSITIES
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    • A—HUMAN NECESSITIES
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    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pulmonology (AREA)
  • Diabetes (AREA)
  • Immunology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Hematology (AREA)
  • Dermatology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Psychiatry (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Otolaryngology (AREA)
  • Psychology (AREA)
  • Hospice & Palliative Care (AREA)
  • Obesity (AREA)

Abstract

"DERIVADOS DE INDOL, SEU PROCESSO DE PREPARAçãO E COMPOSIçõES FARMACêUTICAS CONTENDO OS MESMOS". A presente invenção tem como objetivo compostos de fórmula (I), bem como sua preparação e composições farmacêuticas contendo os mesmos. Estes compostos são ligandos de receptores de canabinóides CB~ 2~.
BR0311185-7A 2002-05-17 2003-05-15 Derivados de indol, seu processo de preparação e composições farmacêuticas contendo os mesmos BR0311185A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0206133A FR2839718B1 (fr) 2002-05-17 2002-05-17 Derives d'indole, leur procede de preparation et les compositions pharmaceutiques en contenant
PCT/FR2003/001470 WO2003097597A2 (fr) 2002-05-17 2003-05-15 Derives d'indole et leur utilisation en tant que ligands des recepteurs cb2

Publications (1)

Publication Number Publication Date
BR0311185A true BR0311185A (pt) 2005-02-22

Family

ID=29286599

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0311185-7A BR0311185A (pt) 2002-05-17 2003-05-15 Derivados de indol, seu processo de preparação e composições farmacêuticas contendo os mesmos

Country Status (20)

Country Link
US (1) US7138424B2 (pt)
EP (1) EP1507758B1 (pt)
JP (1) JP2005530797A (pt)
KR (1) KR20040106560A (pt)
CN (1) CN1668588A (pt)
AT (1) ATE308518T1 (pt)
AU (1) AU2003258762A1 (pt)
BR (1) BR0311185A (pt)
CA (1) CA2482756A1 (pt)
DE (1) DE60302156T2 (pt)
EA (1) EA200401315A1 (pt)
FR (1) FR2839718B1 (pt)
HR (1) HRP20041073A2 (pt)
IL (1) IL164941A0 (pt)
IS (1) IS7513A (pt)
MA (1) MA27203A1 (pt)
MX (1) MXPA04011387A (pt)
NO (1) NO20044970L (pt)
PL (1) PL374111A1 (pt)
WO (1) WO2003097597A2 (pt)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7067539B2 (en) * 2001-02-08 2006-06-27 Schering Corporation Cannabinoid receptor ligands
UY27939A1 (es) 2002-08-21 2004-03-31 Glaxo Group Ltd Compuestos
TW200505902A (en) * 2003-03-20 2005-02-16 Schering Corp Cannabinoid receptor ligands
GB0402355D0 (en) * 2004-02-03 2004-03-10 Glaxo Group Ltd Novel compounds
TW200533657A (en) * 2004-02-17 2005-10-16 Esteve Labor Dr Substituted pyrazoline compounds, their preparation and use as medicaments
CA2587210A1 (en) * 2004-11-22 2006-06-01 Threshold Pharmaceuticals, Inc. Tubulin binding anti cancer agents and prodrugs thereof
EP1743892A1 (en) 2005-07-15 2007-01-17 Laboratorios del Dr. Esteve S.A. Substituted pyrazoline compounds, their preparation and use as medicaments
FR2893615B1 (fr) 2005-11-18 2008-03-07 Sanofi Aventis Sa Derives de 3-acylindole, leur preparation et leur application en therapeutique
GB0702862D0 (en) * 2007-02-14 2007-03-28 Univ Aberdeen Therapeutic compounds
AR068106A1 (es) * 2007-08-29 2009-11-04 Schering Corp Derivados de indol 2-carboxi sustituidos y una composicion farmaceutica
FR2933697B1 (fr) 2008-07-11 2010-08-13 Sanofi Aventis Derives de 1-benzyl-cinnolin-4-(1h)-one substitues, leur preparation et leur application en therapeutique
FR2950055A1 (fr) 2009-09-17 2011-03-18 Sanofi Aventis Derives de 3-amino-cinnolin-4(1h)-one substitues, leur preparation et leur application en therapeutique
FR2983859B1 (fr) 2011-12-12 2014-01-17 Sanofi Sa Derives de 1,3,5-triazine-2-amine, leur preparation et leur application en diagnostique et en therapeutique

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2735774B1 (fr) * 1995-06-21 1997-09-12 Sanofi Sa Utilisation de composes agonistes du recepteur cb2 humain pour la preparation de medicaments immunomodulateurs, nouveaux composes agonistes du recepteur cb2 et les compositions pharmaceutiques les contenant
MXPA02005101A (es) * 1999-10-18 2003-09-25 Alexipharma Inc Derivados de indol canabimimeticos.

Also Published As

Publication number Publication date
KR20040106560A (ko) 2004-12-17
WO2003097597A2 (fr) 2003-11-27
AU2003258762A1 (en) 2003-12-02
EA200401315A1 (ru) 2005-04-28
CN1668588A (zh) 2005-09-14
ATE308518T1 (de) 2005-11-15
EP1507758B1 (fr) 2005-11-02
CA2482756A1 (fr) 2003-11-27
US7138424B2 (en) 2006-11-21
PL374111A1 (en) 2005-10-03
US20060089345A1 (en) 2006-04-27
MXPA04011387A (es) 2005-02-14
MA27203A1 (fr) 2005-01-03
HRP20041073A2 (en) 2004-12-31
JP2005530797A (ja) 2005-10-13
IL164941A0 (en) 2005-12-18
EP1507758A2 (fr) 2005-02-23
DE60302156D1 (de) 2005-12-08
NO20044970L (no) 2005-02-17
WO2003097597A3 (fr) 2004-04-01
DE60302156T2 (de) 2006-07-20
IS7513A (is) 2004-10-20
FR2839718B1 (fr) 2004-06-25
FR2839718A1 (fr) 2003-11-21

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