ATE307215T1 - Verfahren zur erkennung von modulatoren der vegf- kinase-domäne - Google Patents

Verfahren zur erkennung von modulatoren der vegf- kinase-domäne

Info

Publication number
ATE307215T1
ATE307215T1 AT01946127T AT01946127T ATE307215T1 AT E307215 T1 ATE307215 T1 AT E307215T1 AT 01946127 T AT01946127 T AT 01946127T AT 01946127 T AT01946127 T AT 01946127T AT E307215 T1 ATE307215 T1 AT E307215T1
Authority
AT
Austria
Prior art keywords
kinase domain
vegf kinase
modulators
detecting modulators
vegf
Prior art date
Application number
AT01946127T
Other languages
English (en)
Inventor
Dana L Johnson
Stuart L Emanuel
Original Assignee
Ortho Mcneil Pharm Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ortho Mcneil Pharm Inc filed Critical Ortho Mcneil Pharm Inc
Application granted granted Critical
Publication of ATE307215T1 publication Critical patent/ATE307215T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/48Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving transferase
    • C12Q1/485Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving transferase involving kinase
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/71Receptors; Cell surface antigens; Cell surface determinants for growth factors; for growth regulators
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Toxicology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
AT01946127T 2000-06-07 2001-06-06 Verfahren zur erkennung von modulatoren der vegf- kinase-domäne ATE307215T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US21013200P 2000-06-07 2000-06-07
PCT/US2001/018312 WO2001094624A1 (en) 2000-06-07 2001-06-06 Method to detect modulators of vegf kinase domain

Publications (1)

Publication Number Publication Date
ATE307215T1 true ATE307215T1 (de) 2005-11-15

Family

ID=22781690

Family Applications (1)

Application Number Title Priority Date Filing Date
AT01946127T ATE307215T1 (de) 2000-06-07 2001-06-06 Verfahren zur erkennung von modulatoren der vegf- kinase-domäne

Country Status (16)

Country Link
US (1) US7070938B2 (de)
EP (1) EP1294929B1 (de)
JP (1) JP2004508016A (de)
CN (1) CN1457366A (de)
AT (1) ATE307215T1 (de)
AU (2) AU6821301A (de)
BR (1) BR0111530A (de)
CA (1) CA2411072A1 (de)
DE (1) DE60114196T2 (de)
DK (1) DK1294929T3 (de)
ES (1) ES2250420T3 (de)
IL (1) IL153309A0 (de)
MX (1) MXPA02012224A (de)
NZ (1) NZ523386A (de)
WO (1) WO2001094624A1 (de)
ZA (1) ZA200300128B (de)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MY128450A (en) 2000-05-24 2007-02-28 Upjohn Co 1-(pyrrolidin-1-ylmethyl)-3-(pyrrol-2-ylmethylidene)-2-indolinone derivatives

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4568649A (en) 1983-02-22 1986-02-04 Immunex Corporation Immediate ligand detection assay
US5185438A (en) 1991-04-02 1993-02-09 The Trustees Of Princeton University Nucleic acids encoding hencatoporetic stem cell receptor flk-2
US5861301A (en) 1992-02-20 1999-01-19 American Cayanamid Company Recombinant kinase insert domain containing receptor and gene encoding same
US5770176A (en) 1995-12-08 1998-06-23 Chiron Diagnostics Corporation Assays for functional nuclear receptors
AU2066797A (en) * 1996-03-21 1997-10-10 Sugen, Inc. Assays for kdr/flk-1 receptor tyrosine kinase inhibitors
ATE371727T1 (de) 1997-06-18 2007-09-15 Merck & Co Inc Kdr, ein menschlicher tyrosin kinase rezeptor
CA2340598A1 (en) * 1998-09-08 2000-03-16 Agouron Pharmaceuticals, Inc. Modifications of the vegf receptor-2 protein and methods of use

Also Published As

Publication number Publication date
DK1294929T3 (da) 2005-12-12
MXPA02012224A (es) 2004-08-19
IL153309A0 (en) 2003-07-06
EP1294929A4 (de) 2004-12-29
DE60114196T2 (de) 2006-07-20
EP1294929B1 (de) 2005-10-19
ZA200300128B (en) 2004-02-13
NZ523386A (en) 2004-07-30
BR0111530A (pt) 2003-07-22
WO2001094624A1 (en) 2001-12-13
JP2004508016A (ja) 2004-03-18
AU2001268213B2 (en) 2005-11-10
ES2250420T3 (es) 2006-04-16
DE60114196D1 (de) 2006-03-02
US7070938B2 (en) 2006-07-04
US20020037537A1 (en) 2002-03-28
CN1457366A (zh) 2003-11-19
EP1294929A1 (de) 2003-03-26
AU6821301A (en) 2001-12-17
CA2411072A1 (en) 2001-12-13

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