MXPA02012224A - Metodo para detectar moduladores del dominio cinasa del factor de crecimiento endotelial vascular. - Google Patents

Metodo para detectar moduladores del dominio cinasa del factor de crecimiento endotelial vascular.

Info

Publication number
MXPA02012224A
MXPA02012224A MXPA02012224A MXPA02012224A MXPA02012224A MX PA02012224 A MXPA02012224 A MX PA02012224A MX PA02012224 A MXPA02012224 A MX PA02012224A MX PA02012224 A MXPA02012224 A MX PA02012224A MX PA02012224 A MXPA02012224 A MX PA02012224A
Authority
MX
Mexico
Prior art keywords
kinase domain
vegf kinase
modulators
detect modulators
detect
Prior art date
Application number
MXPA02012224A
Other languages
English (en)
Inventor
Stuart L Emanuel
Original Assignee
Johnson & Johnson
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Johnson & Johnson filed Critical Johnson & Johnson
Publication of MXPA02012224A publication Critical patent/MXPA02012224A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/48—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving transferase
    • C12Q1/485—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving transferase involving kinase
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/71—Receptors; Cell surface antigens; Cell surface determinants for growth factors; for growth regulators
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Toxicology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

La presente invencion se refiere a ensayos para la deteccion de compuestos con actividad famacologica, particularmente para la deteccion de moduladores del dominio de cinasa del receptor del factor de crecimiento endotelial vascular (VEGF-R2) de la rata.
MXPA02012224A 2000-06-07 2001-06-06 Metodo para detectar moduladores del dominio cinasa del factor de crecimiento endotelial vascular. MXPA02012224A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US21013200P 2000-06-07 2000-06-07
PCT/US2001/018312 WO2001094624A1 (en) 2000-06-07 2001-06-06 Method to detect modulators of vegf kinase domain

Publications (1)

Publication Number Publication Date
MXPA02012224A true MXPA02012224A (es) 2004-08-19

Family

ID=22781690

Family Applications (1)

Application Number Title Priority Date Filing Date
MXPA02012224A MXPA02012224A (es) 2000-06-07 2001-06-06 Metodo para detectar moduladores del dominio cinasa del factor de crecimiento endotelial vascular.

Country Status (16)

Country Link
US (1) US7070938B2 (es)
EP (1) EP1294929B1 (es)
JP (1) JP2004508016A (es)
CN (1) CN1457366A (es)
AT (1) ATE307215T1 (es)
AU (2) AU6821301A (es)
BR (1) BR0111530A (es)
CA (1) CA2411072A1 (es)
DE (1) DE60114196T2 (es)
DK (1) DK1294929T3 (es)
ES (1) ES2250420T3 (es)
IL (1) IL153309A0 (es)
MX (1) MXPA02012224A (es)
NZ (1) NZ523386A (es)
WO (1) WO2001094624A1 (es)
ZA (1) ZA200300128B (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MY128450A (en) 2000-05-24 2007-02-28 Upjohn Co 1-(pyrrolidin-1-ylmethyl)-3-(pyrrol-2-ylmethylidene)-2-indolinone derivatives

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4568649A (en) 1983-02-22 1986-02-04 Immunex Corporation Immediate ligand detection assay
US5185438A (en) 1991-04-02 1993-02-09 The Trustees Of Princeton University Nucleic acids encoding hencatoporetic stem cell receptor flk-2
US5861301A (en) 1992-02-20 1999-01-19 American Cayanamid Company Recombinant kinase insert domain containing receptor and gene encoding same
US5770176A (en) 1995-12-08 1998-06-23 Chiron Diagnostics Corporation Assays for functional nuclear receptors
AU2066797A (en) * 1996-03-21 1997-10-10 Sugen, Inc. Assays for kdr/flk-1 receptor tyrosine kinase inhibitors
ATE371727T1 (de) 1997-06-18 2007-09-15 Merck & Co Inc Kdr, ein menschlicher tyrosin kinase rezeptor
CA2340598A1 (en) * 1998-09-08 2000-03-16 Agouron Pharmaceuticals, Inc. Modifications of the vegf receptor-2 protein and methods of use

Also Published As

Publication number Publication date
DK1294929T3 (da) 2005-12-12
IL153309A0 (en) 2003-07-06
EP1294929A4 (en) 2004-12-29
DE60114196T2 (de) 2006-07-20
EP1294929B1 (en) 2005-10-19
ZA200300128B (en) 2004-02-13
NZ523386A (en) 2004-07-30
BR0111530A (pt) 2003-07-22
WO2001094624A1 (en) 2001-12-13
JP2004508016A (ja) 2004-03-18
AU2001268213B2 (en) 2005-11-10
ES2250420T3 (es) 2006-04-16
DE60114196D1 (de) 2006-03-02
US7070938B2 (en) 2006-07-04
US20020037537A1 (en) 2002-03-28
CN1457366A (zh) 2003-11-19
EP1294929A1 (en) 2003-03-26
ATE307215T1 (de) 2005-11-15
AU6821301A (en) 2001-12-17
CA2411072A1 (en) 2001-12-13

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