ATE305008T1 - Gonadotropin freisetzenden hormon rezeptor antagonisten und ihre verwandten verwendungen - Google Patents
Gonadotropin freisetzenden hormon rezeptor antagonisten und ihre verwandten verwendungenInfo
- Publication number
- ATE305008T1 ATE305008T1 AT00973591T AT00973591T ATE305008T1 AT E305008 T1 ATE305008 T1 AT E305008T1 AT 00973591 T AT00973591 T AT 00973591T AT 00973591 T AT00973591 T AT 00973591T AT E305008 T1 ATE305008 T1 AT E305008T1
- Authority
- AT
- Austria
- Prior art keywords
- receptor antagonists
- releasing hormone
- hormone receptor
- gonadotropin releasing
- related uses
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/02—Drugs for disorders of the endocrine system of the hypothalamic hormones, e.g. TRH, GnRH, CRH, GRH, somatostatin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/02—Drugs for disorders of the endocrine system of the hypothalamic hormones, e.g. TRH, GnRH, CRH, GRH, somatostatin
- A61P5/04—Drugs for disorders of the endocrine system of the hypothalamic hormones, e.g. TRH, GnRH, CRH, GRH, somatostatin for decreasing, blocking or antagonising the activity of the hypothalamic hormones
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Endocrinology (AREA)
- Diabetes (AREA)
- Dermatology (AREA)
- Reproductive Health (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US41876899A | 1999-10-15 | 1999-10-15 | |
PCT/US2000/028677 WO2001029044A1 (en) | 1999-10-15 | 2000-10-16 | Gonadotropin-releasing hormone receptor antagonists and methods relating thereto |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE305008T1 true ATE305008T1 (de) | 2005-10-15 |
Family
ID=23659500
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT00973591T ATE305008T1 (de) | 1999-10-15 | 2000-10-16 | Gonadotropin freisetzenden hormon rezeptor antagonisten und ihre verwandten verwendungen |
Country Status (11)
Country | Link |
---|---|
EP (1) | EP1220857B1 (de) |
JP (1) | JP2003512379A (de) |
KR (1) | KR20020045609A (de) |
AT (1) | ATE305008T1 (de) |
AU (1) | AU769855B2 (de) |
CA (1) | CA2386942A1 (de) |
DE (1) | DE60022769T2 (de) |
ES (1) | ES2249302T3 (de) |
HK (1) | HK1047437B (de) |
MX (1) | MXPA02003614A (de) |
WO (1) | WO2001029044A1 (de) |
Families Citing this family (22)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP4931314B2 (ja) | 2000-01-25 | 2012-05-16 | ニューロクライン バイオサイエンシーズ,インコーポレイテッド | 性腺刺激ホルモン放出ホルモンレセプタアンタゴニストおよびそれに関連した方法 |
US7288517B2 (en) | 2001-04-30 | 2007-10-30 | Aeterna Zentaris Gmbh | Treatment of dementia and neurodegenerative diseases with intermediate doses of LHRH antagonists |
EP1412363A1 (de) * | 2001-08-02 | 2004-04-28 | Neurocrine Biosciences, Inc. | Rezeptor antagonisten für gonadotropin-freisetzende hormone |
AU2002324586B2 (en) | 2001-08-02 | 2008-04-24 | Neurocrine Biosciences, Inc. | 1,3,5-triazine-2,4,6-triones, preparation and use as gonadotropin-releasing hormone receptor antagonists |
MXPA04000986A (es) | 2001-08-02 | 2005-02-17 | Neurocrine Biosciences Inc | 1,2,3-triazin-3,5-dionas sustituidas como antagonistas del receptor de hormona de liberacion de gonadotropina (gnrh). |
JP2005505525A (ja) * | 2001-08-02 | 2005-02-24 | ニューロクライン バイオサイエンシーズ, インコーポレイテッド | 性腺刺激ホルモン放出ホルモンレセプターアンタゴニストおよびそれに関連する方法 |
EP1411941A2 (de) | 2001-08-02 | 2004-04-28 | Neurocrine Biosciences, Inc. | Pyridinon- und pyridazinonderivate als antagonisten des gonadotropin-freisetzungshormon-rezeptors |
AU2003202115A1 (en) | 2002-02-12 | 2003-09-04 | Pfizer Inc. | Non-peptide compounds affecting the action of gonadotropin-releasing hormone (gnrh) |
BR0312123A (pt) | 2002-06-13 | 2005-03-29 | Pfizer | Agentes de gnrh não peptìdicos, composições farmacêuticas e métodos para o seu uso |
CN100376246C (zh) | 2003-07-07 | 2008-03-26 | 纽罗克里生物科学有限公司 | 作为促性激素释放激素受体拮抗剂的嘧啶-2,4-二酮衍生物 |
WO2005007633A1 (en) | 2003-07-07 | 2005-01-27 | Neurocrine Biosciences, Inc. | Gonadotropin-releasing hormone receptor antagonists and methods relating thereto |
CN100424078C (zh) | 2003-07-07 | 2008-10-08 | 纽罗克里生物科学有限公司 | 作为促性激素释放激素受体拮抗剂的嘧啶-2,4-二酮衍生物 |
CL2008000985A1 (es) | 2007-04-06 | 2008-10-10 | Neurocrine Biosciences Inc | Compuesto derivado de heterociclos de nitrogeno, agonistas del receptor gnrh; composicion farmaceutica que comprende a dicho compuesto; y uso para tratar una afeccion relacionada con las hormonas sexuales, endometriosis, dismenorrea, enfermedad de ov |
WO2008124614A1 (en) | 2007-04-06 | 2008-10-16 | Neurocrine Biosciences, Inc. | Gonadotropin-releasing hormone receptor antagonists and methods relating thereto |
JP5637859B2 (ja) * | 2007-12-13 | 2014-12-10 | バーテックス ファーマシューティカルズ インコーポレイテッドVertex Pharmaceuticals Incorporated | 嚢胞性線維症膜コンダクタンスレギュレーターのモジュレーター |
CN101987865B (zh) * | 2009-07-29 | 2014-07-30 | 中国人民解放军军事医学科学院毒物药物研究所 | 含有乙内酰脲结构的促黄体生成素释放激素拮抗剂 |
TW201130854A (en) | 2009-12-22 | 2011-09-16 | Bayer Schering Pharma Ag | Pyridinone derivatives and pharmaceutical compositions thereof |
WO2012175514A1 (en) | 2011-06-21 | 2012-12-27 | Bayer Intellectual Property Gmbh | Pyridinone derivatives and pharmaceutical compositions thereof |
MX357841B (es) * | 2012-02-28 | 2018-07-26 | Tiumbio Co Ltd | Antagonistas de los receptores de la hormona liberadora de gonadotropina, método para la preparación de éstos y composición farmacéutica que los contienen. |
WO2014133112A1 (ja) * | 2013-03-01 | 2014-09-04 | 国立大学法人東京大学 | オートタキシン阻害活性を有する8-置換イミダゾピリミジノン誘導体 |
KR101973074B1 (ko) * | 2018-11-30 | 2019-04-26 | 주식회사 티움바이오 | 퓨로피리미딘 화합물의 염 및 결정형, 및 이를 포함하는 약학적 조성물 |
MX2022006281A (es) | 2019-11-25 | 2022-06-08 | Amgen Inc | Compuestos heterociclicos como inhibidores de delta-5 desaturasa y metodos de uso. |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2300479A1 (en) * | 1997-12-26 | 1999-07-08 | Shuichi Furuya | Nitrogen-containing heterocyclic compounds, their production and use |
US6081508A (en) * | 1998-02-25 | 2000-06-27 | Indus River Networks, Inc. | Remote computer communication |
AU3118399A (en) * | 1998-04-02 | 1999-10-25 | Merck & Co., Inc. | Antagonists of gonadotropin releasing hormone |
-
2000
- 2000-10-16 KR KR1020027004773A patent/KR20020045609A/ko not_active Application Discontinuation
- 2000-10-16 EP EP00973591A patent/EP1220857B1/de not_active Expired - Lifetime
- 2000-10-16 WO PCT/US2000/028677 patent/WO2001029044A1/en active Search and Examination
- 2000-10-16 DE DE60022769T patent/DE60022769T2/de not_active Expired - Fee Related
- 2000-10-16 ES ES00973591T patent/ES2249302T3/es not_active Expired - Lifetime
- 2000-10-16 AT AT00973591T patent/ATE305008T1/de not_active IP Right Cessation
- 2000-10-16 MX MXPA02003614A patent/MXPA02003614A/es active IP Right Grant
- 2000-10-16 AU AU12089/01A patent/AU769855B2/en not_active Ceased
- 2000-10-16 CA CA002386942A patent/CA2386942A1/en not_active Abandoned
- 2000-10-16 JP JP2001531842A patent/JP2003512379A/ja active Pending
-
2002
- 2002-12-16 HK HK02109095.3A patent/HK1047437B/zh not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
ES2249302T3 (es) | 2006-04-01 |
WO2001029044A1 (en) | 2001-04-26 |
JP2003512379A (ja) | 2003-04-02 |
AU1208901A (en) | 2001-04-30 |
HK1047437B (zh) | 2005-12-16 |
CA2386942A1 (en) | 2001-04-26 |
DE60022769T2 (de) | 2006-07-06 |
HK1047437A1 (en) | 2003-02-21 |
AU769855B2 (en) | 2004-02-05 |
EP1220857A1 (de) | 2002-07-10 |
KR20020045609A (ko) | 2002-06-19 |
MXPA02003614A (es) | 2002-10-23 |
EP1220857B1 (de) | 2005-09-21 |
DE60022769D1 (de) | 2006-02-02 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |