ATE303151T1 - Verwendung von mntbap zur behandlung von hepatischer insuffizienz - Google Patents
Verwendung von mntbap zur behandlung von hepatischer insuffizienzInfo
- Publication number
- ATE303151T1 ATE303151T1 AT01919589T AT01919589T ATE303151T1 AT E303151 T1 ATE303151 T1 AT E303151T1 AT 01919589 T AT01919589 T AT 01919589T AT 01919589 T AT01919589 T AT 01919589T AT E303151 T1 ATE303151 T1 AT E303151T1
- Authority
- AT
- Austria
- Prior art keywords
- mntbap
- hepatic insufficiency
- treat hepatic
- medicine
- insufficiency
- Prior art date
Links
- 208000000857 Hepatic Insufficiency Diseases 0.000 title 1
- 206010019663 Hepatic failure Diseases 0.000 title 1
- OAWZTKNCHQQRKF-UHFFFAOYSA-L manganese(3+);4-[10,15,20-tris(4-carboxyphenyl)porphyrin-22,24-diid-5-yl]benzoic acid Chemical compound [Mn+3].C1=CC(C(=O)O)=CC=C1C(C1=CC=C([N-]1)C(C=1C=CC(=CC=1)C(O)=O)=C1C=CC(=N1)C(C=1C=CC(=CC=1)C(O)=O)=C1C=CC([N-]1)=C1C=2C=CC(=CC=2)C(O)=O)=C2N=C1C=C2 OAWZTKNCHQQRKF-UHFFFAOYSA-L 0.000 title 1
- 239000003814 drug Substances 0.000 abstract 2
- OUUQCZGPVNCOIJ-UHFFFAOYSA-M Superoxide Chemical compound [O-][O] OUUQCZGPVNCOIJ-UHFFFAOYSA-M 0.000 abstract 1
- 102000019197 Superoxide Dismutase Human genes 0.000 abstract 1
- 108010012715 Superoxide dismutase Proteins 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 238000009109 curative therapy Methods 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 230000003449 preventive effect Effects 0.000 abstract 1
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 1
- 231100000331 toxic Toxicity 0.000 abstract 1
- 230000002588 toxic effect Effects 0.000 abstract 1
- 230000003612 virological effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/44—Oxidoreductases (1)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/44—Oxidoreductases (1)
- A61K38/446—Superoxide dismutase (1.15)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/06—Free radical scavengers or antioxidants
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y111/00—Oxidoreductases acting on a peroxide as acceptor (1.11)
- C12Y111/01—Peroxidases (1.11.1)
- C12Y111/01006—Catalase (1.11.1.6)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y111/00—Oxidoreductases acting on a peroxide as acceptor (1.11)
- C12Y111/01—Peroxidases (1.11.1)
- C12Y111/01009—Glutathione peroxidase (1.11.1.9)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y115/00—Oxidoreductases acting on superoxide as acceptor (1.15)
- C12Y115/01—Oxidoreductases acting on superoxide as acceptor (1.15) with NAD or NADP as acceptor (1.15.1)
- C12Y115/01001—Superoxide dismutase (1.15.1.1)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Biochemistry (AREA)
- Wood Science & Technology (AREA)
- General Engineering & Computer Science (AREA)
- Zoology (AREA)
- Genetics & Genomics (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Toxicology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Enzymes And Modification Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR0003887A FR2806911B1 (fr) | 2000-03-28 | 2000-03-28 | Utilisation de mimetiques de la sod dans le traitement d'insuffisances hepatocellulaires |
| PCT/FR2001/000939 WO2001072327A2 (fr) | 2000-03-28 | 2001-03-28 | Utilisation de mimetiques de la sod dans le traitement d'insuffisances hepatocellulaires |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE303151T1 true ATE303151T1 (de) | 2005-09-15 |
Family
ID=8848555
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT01919589T ATE303151T1 (de) | 2000-03-28 | 2001-03-28 | Verwendung von mntbap zur behandlung von hepatischer insuffizienz |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US20030118577A1 (de) |
| EP (1) | EP1267881B1 (de) |
| JP (1) | JP2003528152A (de) |
| AT (1) | ATE303151T1 (de) |
| AU (1) | AU2001246657A1 (de) |
| CA (1) | CA2404077A1 (de) |
| DE (1) | DE60113078T2 (de) |
| FR (1) | FR2806911B1 (de) |
| WO (1) | WO2001072327A2 (de) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7299082B2 (en) | 2003-10-31 | 2007-11-20 | Abbott Diabetes Care, Inc. | Method of calibrating an analyte-measurement device, and associated methods, devices and systems |
| US8165651B2 (en) * | 2004-02-09 | 2012-04-24 | Abbott Diabetes Care Inc. | Analyte sensor, and associated system and method employing a catalytic agent |
| US7699964B2 (en) | 2004-02-09 | 2010-04-20 | Abbott Diabetes Care Inc. | Membrane suitable for use in an analyte sensor, analyte sensor, and associated method |
| US7885698B2 (en) | 2006-02-28 | 2011-02-08 | Abbott Diabetes Care Inc. | Method and system for providing continuous calibration of implantable analyte sensors |
| US20100086519A1 (en) * | 2008-10-03 | 2010-04-08 | The Charlotte-Mecklenburg Hospital Authority D/B/A Carolinas Medical Center | Treatment of Hepatitis C Infection With Metalloporphyrins |
| RU2683203C2 (ru) | 2013-12-31 | 2019-03-26 | Эбботт Дайабитиз Кэр Инк. | Снабженный автономным питанием датчик аналита и использующие его устройства |
| CN113693189B (zh) * | 2021-09-28 | 2023-11-17 | 中国农业科学院北京畜牧兽医研究所 | 锰过氧化物酶用于降解棒曲霉素的应用及方法 |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH0653670B2 (ja) * | 1985-10-28 | 1994-07-20 | 日研フ−ド株式会社 | 化学療法剤の副作用低減化剤 |
| ES2083357T3 (es) * | 1987-03-14 | 1996-04-16 | Boehringer Ingelheim Int | Manganeso-superoxido-dismutasa humana (hmn-sod). |
| JPS6490133A (en) * | 1987-09-29 | 1989-04-06 | Otsuka Pharma Co Ltd | Pharmaceutical preparation for oral administration |
| JPH01238537A (ja) * | 1988-03-18 | 1989-09-22 | Toyo Jozo Co Ltd | 肝障害治療剤 |
| JPH0420285A (ja) * | 1990-05-15 | 1992-01-23 | Asahi Chem Ind Co Ltd | Ｓｏｄ誘導体 |
| CA2072934C (en) * | 1991-07-19 | 2007-08-28 | Karl William Aston | Manganese complexes of nitrogen-containing macrocyclic ligands effective as catalysts for dismutating superoxide |
| US5834509A (en) * | 1992-12-07 | 1998-11-10 | Eukarion, Inc. | Synthetic catalytic free radical scavengers useful as antioxidants for prevention and therapy of disease |
| US6204259B1 (en) * | 1993-01-14 | 2001-03-20 | Monsanto Company | Manganese complexes of nitrogen-containing macrocyclic ligands effective as catalysts for dismutating superoxide |
| US5747026A (en) * | 1993-10-15 | 1998-05-05 | University Of Alabama At Birmingham Research Foundation | Antioxidants |
| PL317192A1 (en) * | 1994-05-13 | 1997-03-17 | Monsanto Co | Methods of using pernitrite decomposition catalyst and their pharmaceutic compositions |
| JP2001521939A (ja) * | 1997-11-03 | 2001-11-13 | デューク・ユニバーシティー | 置換されたポルフィリン類 |
| WO2000023568A2 (en) * | 1998-10-06 | 2000-04-27 | Albert Einstein College Of Medicine Of Yeshiva University | Methods and compositions for decreasing mitochondrial overproduction of reactive oxygen species in cells |
| KR100873690B1 (ko) * | 1999-01-19 | 2008-12-12 | 유니버시티 오브 노스캐롤라이나 앳 채플 힐 | 인간 간 전구세포 |
| EP1155019B1 (de) * | 1999-01-25 | 2005-12-07 | National Jewish Medical and Research Center | Substituierte porphyrine und deren therapeutische verwendungen |
-
2000
- 2000-03-28 FR FR0003887A patent/FR2806911B1/fr not_active Expired - Fee Related
-
2001
- 2001-03-28 CA CA002404077A patent/CA2404077A1/fr not_active Abandoned
- 2001-03-28 WO PCT/FR2001/000939 patent/WO2001072327A2/fr not_active Ceased
- 2001-03-28 AT AT01919589T patent/ATE303151T1/de not_active IP Right Cessation
- 2001-03-28 AU AU2001246657A patent/AU2001246657A1/en not_active Abandoned
- 2001-03-28 JP JP2001570288A patent/JP2003528152A/ja active Pending
- 2001-03-28 EP EP01919589A patent/EP1267881B1/de not_active Expired - Lifetime
- 2001-03-28 US US10/240,270 patent/US20030118577A1/en not_active Abandoned
- 2001-03-28 DE DE60113078T patent/DE60113078T2/de not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| AU2001246657A1 (en) | 2001-10-08 |
| DE60113078D1 (de) | 2005-10-06 |
| US20030118577A1 (en) | 2003-06-26 |
| WO2001072327A3 (fr) | 2002-03-28 |
| FR2806911B1 (fr) | 2003-01-10 |
| FR2806911A1 (fr) | 2001-10-05 |
| JP2003528152A (ja) | 2003-09-24 |
| CA2404077A1 (fr) | 2001-10-04 |
| DE60113078T2 (de) | 2006-07-13 |
| EP1267881B1 (de) | 2005-08-31 |
| EP1267881A2 (de) | 2003-01-02 |
| WO2001072327A2 (fr) | 2001-10-04 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |