ATE301993T1 - Antineoplastische, antivirale oder antiretrovirale sperminderivate - Google Patents
Antineoplastische, antivirale oder antiretrovirale sperminderivateInfo
- Publication number
- ATE301993T1 ATE301993T1 AT89306425T AT89306425T ATE301993T1 AT E301993 T1 ATE301993 T1 AT E301993T1 AT 89306425 T AT89306425 T AT 89306425T AT 89306425 T AT89306425 T AT 89306425T AT E301993 T1 ATE301993 T1 AT E301993T1
- Authority
- AT
- Austria
- Prior art keywords
- antiretroviral
- antineoplastic
- sperm
- antiviral
- derivatives
- Prior art date
Links
- 230000000118 anti-neoplastic effect Effects 0.000 title abstract 2
- 230000000840 anti-viral effect Effects 0.000 title abstract 2
- 230000000798 anti-retroviral effect Effects 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 125000003710 aryl alkyl group Chemical group 0.000 abstract 2
- 125000004432 carbon atom Chemical group C* 0.000 abstract 2
- 241000238631 Hexapoda Species 0.000 abstract 1
- 229940034982 antineoplastic agent Drugs 0.000 abstract 1
- 229940030999 antipsoriatics Drugs 0.000 abstract 1
- 238000011225 antiretroviral therapy Methods 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/04—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N33/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic nitrogen compounds
- A01N33/02—Amines; Quaternary ammonium compounds
- A01N33/04—Nitrogen directly attached to aliphatic or cycloaliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/48—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with two nitrogen atoms as the only ring hetero atoms
- A01N43/54—1,3-Diazines; Hydrogenated 1,3-diazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/131—Amines acyclic
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/74—Synthetic polymeric materials
- A61K31/785—Polymers containing nitrogen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
- A61P33/06—Antimalarials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C209/00—Preparation of compounds containing amino groups bound to a carbon skeleton
- C07C209/04—Preparation of compounds containing amino groups bound to a carbon skeleton by substitution of functional groups by amino groups
- C07C209/06—Preparation of compounds containing amino groups bound to a carbon skeleton by substitution of functional groups by amino groups by substitution of halogen atoms
- C07C209/08—Preparation of compounds containing amino groups bound to a carbon skeleton by substitution of functional groups by amino groups by substitution of halogen atoms with formation of amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C209/00—Preparation of compounds containing amino groups bound to a carbon skeleton
- C07C209/62—Preparation of compounds containing amino groups bound to a carbon skeleton by cleaving carbon-to-nitrogen, sulfur-to-nitrogen, or phosphorus-to-nitrogen bonds, e.g. hydrolysis of amides, N-dealkylation of amines or quaternary ammonium compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C211/00—Compounds containing amino groups bound to a carbon skeleton
- C07C211/01—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms
- C07C211/02—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton
- C07C211/14—Amines containing amino groups bound to at least two aminoalkyl groups, e.g. diethylenetriamines
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Environmental Sciences (AREA)
- Agronomy & Crop Science (AREA)
- Pest Control & Pesticides (AREA)
- Plant Pathology (AREA)
- Dentistry (AREA)
- Wood Science & Technology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Tropical Medicine & Parasitology (AREA)
- Virology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Dermatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US07/210,520 US5091576A (en) | 1986-12-02 | 1988-06-23 | Anti-neoplastic, anti-viral or anti-retroviral spermine derivatives |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE301993T1 true ATE301993T1 (de) | 2005-09-15 |
Family
ID=22783232
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT89306425T ATE301993T1 (de) | 1988-06-23 | 1989-06-23 | Antineoplastische, antivirale oder antiretrovirale sperminderivate |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US5091576A (de) |
| EP (1) | EP0349224B1 (de) |
| JP (3) | JP2673136B2 (de) |
| AT (1) | ATE301993T1 (de) |
| CA (1) | CA1340773C (de) |
| DE (1) | DE68929539T2 (de) |
| ES (1) | ES2244953T3 (de) |
Families Citing this family (48)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6262125B1 (en) | 1986-12-02 | 2001-07-17 | University Of Florida Research Foundation, Inc. | Sterically hindered tetraamines and method for their production |
| US6184232B1 (en) * | 1986-12-02 | 2001-02-06 | University Of Florida | Analogs of biologically active, naturally occurring polyamines, pharmaceutical compositions and methods of treatment |
| US5393757A (en) * | 1986-12-02 | 1995-02-28 | University Of Florida | Polyamines and anti-diarrheal and gastrointestinal anti-spasmodic pharmaceutical compositions and methods of treatment |
| US5342945A (en) * | 1986-12-02 | 1994-08-30 | University Of Florida Research Foundation, Inc. | Anti-neoplastic, anti-viral or anti-retroviral spermine derivatives |
| US5753714A (en) * | 1987-02-03 | 1998-05-19 | Merrell Pharmaceuticals Inc. | Polyamine derivatives |
| US5654484A (en) * | 1987-10-08 | 1997-08-05 | Merrell Pharmaceuticals Inc. | Polyamine derivatives as antineoplastic agents |
| US5354782A (en) * | 1991-01-17 | 1994-10-11 | Merrell Dow Pharmaceuticals Inc. | Polyamine phenols as radioprotective agents |
| GB9105489D0 (en) * | 1991-03-15 | 1991-05-01 | Johnson Matthey Plc | Improvements in chemical compounds |
| US5814666A (en) * | 1992-04-13 | 1998-09-29 | The United States As Represented By The Department Of Health And Human Services | Encapsulated and non-encapsulated nitric oxide generators used as antimicrobial agents |
| EP0600342A1 (de) * | 1992-12-04 | 1994-06-08 | F. Hoffmann-La Roche Ag | Hispidospermidin und pharmazeutische Zubereitungen |
| AU5076293A (en) * | 1992-12-04 | 1994-06-16 | F. Hoffmann-La Roche Ag | Hispidospermidin |
| AU679972B2 (en) * | 1993-02-23 | 1997-07-17 | Merrell Dow Pharmaceuticals Inc. | Polyamine derivatives as radioprotective agents |
| DK0700380T3 (da) * | 1993-05-26 | 1998-11-09 | Merrell Pharma Inc | N-Alkylthiopolyaminderivater som radioprotektive midler |
| WO1995009832A1 (en) * | 1993-10-07 | 1995-04-13 | Merrell Dow Pharmaceuticals Inc. | Novel process for preparing polyamine derivatives and intermediates thereof |
| US5541230A (en) * | 1993-11-05 | 1996-07-30 | Us Health | Therapeutic polyamines |
| US5674908A (en) | 1993-12-20 | 1997-10-07 | Life Technologies, Inc. | Highly packed polycationic ammonium, sulfonium and phosphonium lipids |
| FR2714052B1 (fr) * | 1993-12-22 | 1996-02-02 | Synthelabo | Préparation de polyamines substituées sur les deux azotes terminaux. |
| DE69412467T2 (de) * | 1993-12-27 | 1999-01-28 | Novartis Ag, Basel | Ungesättigte aminoverbindungen zur verwendung als antikrebsmittel und als mittelgegen protozoen |
| US5510390A (en) * | 1994-01-28 | 1996-04-23 | University Of Florida Research Foundation, Inc. | Anti-hypertensive composition and methods of treatment |
| US5516807A (en) * | 1994-10-25 | 1996-05-14 | Warner-Lambert Company | Method for treating vascular proliferative disorders following balloon angioplasty |
| ATE206396T1 (de) * | 1995-03-15 | 2001-10-15 | Novartis Erfind Verwalt Gmbh | Piperidenyl-2-alkyl substituierte lineare polyamine zur senkung intrazellulärer, endogener polyaminkonzentrationen wie z.b. putrescin, spermidin und spermin und ihr einfluss auf die zellvermehrung |
| US5744335A (en) * | 1995-09-19 | 1998-04-28 | Mirus Corporation | Process of transfecting a cell with a polynucleotide mixed with an amphipathic compound and a DNA-binding protein |
| JP3470901B2 (ja) * | 1996-09-13 | 2003-11-25 | ユニヴァーシティ オブ フロリダ リサーチ ファウンデーション,インコーポレイテッド | Elf5A生合成の抑制方法 |
| WO1998017624A1 (en) * | 1996-10-18 | 1998-04-30 | Wisconsin Alumni Research Foundation | Conformationally restricted polyamines and their use as antineoplastic agents |
| US6083991A (en) * | 1997-06-04 | 2000-07-04 | University Of Florida Research Foundation, Inc. | Anti-arrhythmic composition and methods of treatment |
| US5889061A (en) * | 1997-10-15 | 1999-03-30 | Wisconsin Alumni Research Foundation | Conformationally restricted polyamines |
| US7087648B1 (en) * | 1997-10-27 | 2006-08-08 | The Regents Of The University Of California | Methods for modulating macrophage proliferation using polyamine analogs |
| US8198334B2 (en) * | 1997-10-27 | 2012-06-12 | Pathologica Llc | Methods for modulating macrophage proliferation in ocular disease using polyamine analogs |
| PT1129064E (pt) | 1998-11-12 | 2008-01-31 | Invitrogen Corp | Reagentes de transfecção |
| US6649587B1 (en) * | 1999-04-30 | 2003-11-18 | Slil Biomedical Corporation | Polyamine analog conjugates and quinone conjugates as therapies for cancers and prostate diseases |
| AU4678300A (en) * | 1999-04-30 | 2000-11-17 | Slil Biomedical Corporation | Novel polyamine analog conjugates and quinone conjugates as therapies for cancers and prostate diseases |
| HK1040993B (en) * | 1999-04-30 | 2006-11-10 | Cellgate, Inc. | Polyamines and their use in therapy |
| AU2002235126A1 (en) * | 2000-11-08 | 2002-05-21 | Slil Biomedical Corporation | Novel polyamine analog-amino acid conjugates useful as anticancer agents |
| US6399662B1 (en) * | 2000-12-13 | 2002-06-04 | University Of Florida | Method and composition for the treatment of diarrhea and gastrointestinal spasms |
| WO2002062341A1 (en) * | 2001-02-07 | 2002-08-15 | University Of Florida | Method and composition for the control of hair growth |
| US7045550B2 (en) * | 2001-08-07 | 2006-05-16 | Wisconsin Alumni Research Foundation | Polyamines and analogs for protecting cells during cancer chemotherapy and radiotherapy |
| CA2463771A1 (en) * | 2001-10-16 | 2003-04-24 | Slil Biomedical Corporation | Oligoamine compounds and derivatives thereof for cancer therapy |
| US20030185778A1 (en) * | 2002-02-07 | 2003-10-02 | Fahl William E. | Polyamine compounds and compositions for use in conjunction with cancer therapy |
| GB2389581A (en) * | 2002-06-12 | 2003-12-17 | Viaxxel Biotech Gmbh | Hydrogenated pyrimidines and their use as inhibitors of deoxyhypusine-synthase or hypusination of eIF-5A |
| US7353532B2 (en) * | 2002-08-30 | 2008-04-01 | International Business Machines Corporation | Secure system and method for enforcement of privacy policy and protection of confidentiality |
| US7829543B2 (en) | 2003-01-07 | 2010-11-09 | Paratek Pharmaceuticals, Inc. | Substituted polyamines as inhibitors of bacterial efflux pumps |
| JP4709552B2 (ja) * | 2003-02-19 | 2011-06-22 | 邦康 早田 | Lfa−1抑制剤、及びその用途 |
| WO2005023310A2 (en) * | 2003-09-09 | 2005-03-17 | University Of Florida Research Foundation, Inc. | Polyamine-metal chelator conjugates |
| US7423182B2 (en) * | 2004-11-03 | 2008-09-09 | University Of Florida | Aminated polyamines |
| AU2006279943B2 (en) * | 2005-08-10 | 2012-02-16 | The Johns Hopkins University | Polyamines useful as anti-parasitic and anti-cancer therapeutics and as lysine-specific demethylase inhibitors |
| GB0605107D0 (en) * | 2006-03-14 | 2006-04-26 | Bioforskning As | Use |
| WO2016011203A1 (en) | 2014-07-15 | 2016-01-21 | Life Technologies Corporation | Compositions with lipid aggregates and methods for efficient delivery of molecules to cells |
| CN113016714B (zh) * | 2021-03-04 | 2023-08-22 | 湖南中医药大学 | 一种泄泻食滞胃肠证动物模型的制备方法 |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2267204A (en) * | 1938-07-30 | 1941-12-23 | Monsanto Chemicals | Insecticide |
| US2279294A (en) * | 1940-04-24 | 1942-04-14 | Wingfoot Corp | Polyalkylene polyamines |
| US2638450A (en) * | 1950-01-17 | 1953-05-12 | Socony Vacuum Oil Co Inc | Reaction products of nu-alkylated polyalkylenepolyamines and alkenyl succinic acid anhydrides |
| US2687348A (en) * | 1952-09-17 | 1954-08-24 | Monsanto Chemicals | Herbicidal compositions |
| JPS606348B2 (ja) * | 1976-03-31 | 1985-02-18 | 三菱化学株式会社 | 新規ポリアミン類 |
| US4507321A (en) * | 1982-02-17 | 1985-03-26 | The Research Foundation Of State University Of New York | Epithelial cell growth regulating composition containing polyamines and a method of using same |
| US4505861A (en) * | 1982-07-23 | 1985-03-19 | University Of Florida | Methods and intermediates for the preparation of spermidine, homospermidine and norspermidine |
| JPS5927912A (ja) * | 1982-08-06 | 1984-02-14 | Kao Corp | ポリウレタンフオ−ムの製造法 |
| NZ212053A (en) * | 1984-05-17 | 1988-02-29 | Merrell Dow Pharma | Polyamine containing pharmaceutical compositions for treating neoplasms |
| JPS63115893A (ja) * | 1986-10-31 | 1988-05-20 | Dick Hercules Kk | 糖質のエピ化方法 |
| CA1305425C (en) * | 1986-12-02 | 1992-07-21 | Raymond J. Bergeron | Anti-neoplastic spermine derivative |
| ZA887410B (en) * | 1987-10-08 | 1989-06-28 | Merrell Dow Pharma | Polyamine derivatives as antineoplastic agents |
-
1988
- 1988-06-23 US US07/210,520 patent/US5091576A/en not_active Ceased
-
1989
- 1989-06-21 CA CA000603449A patent/CA1340773C/en not_active Expired - Fee Related
- 1989-06-23 DE DE68929539T patent/DE68929539T2/de not_active Expired - Lifetime
- 1989-06-23 AT AT89306425T patent/ATE301993T1/de not_active IP Right Cessation
- 1989-06-23 JP JP1162480A patent/JP2673136B2/ja not_active Expired - Lifetime
- 1989-06-23 EP EP89306425A patent/EP0349224B1/de not_active Expired - Lifetime
- 1989-06-23 ES ES89306425T patent/ES2244953T3/es not_active Expired - Lifetime
-
1994
- 1994-09-08 JP JP6240744A patent/JP2748333B2/ja not_active Expired - Lifetime
-
1997
- 1997-11-13 JP JP9329524A patent/JP2945360B2/ja not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| EP0349224B1 (de) | 2005-08-17 |
| JPH10168067A (ja) | 1998-06-23 |
| DE68929539D1 (de) | 2005-09-22 |
| JPH02117647A (ja) | 1990-05-02 |
| JP2748333B2 (ja) | 1998-05-06 |
| ES2244953T3 (es) | 2005-12-16 |
| JP2673136B2 (ja) | 1997-11-05 |
| EP0349224A2 (de) | 1990-01-03 |
| JP2945360B2 (ja) | 1999-09-06 |
| US5091576A (en) | 1992-02-25 |
| DE68929539T2 (de) | 2006-06-29 |
| CA1340773C (en) | 1999-09-28 |
| JPH07252193A (ja) | 1995-10-03 |
| EP0349224A3 (de) | 1992-01-22 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DE68929539D1 (de) | Antineoplastische, antivirale oder antiretrovirale Sperminderivate | |
| ATE116306T1 (de) | Hypoglykämische oxazolidindion-derivate. | |
| NL350027I1 (nl) | Pyridine-amiden en zouten hiervan, werkwijzen voorhet bereiden hiervan en pesticide-samenstellingen die deze verbindingen bevatten. | |
| NO920210L (no) | Antivirale pyrimidinnukleosider | |
| ATE107294T1 (de) | Thiazolderivate mit 5-lipoxygenase-hemmender wirkung. | |
| DE68917341D1 (de) | Benzophenon-Derivate. | |
| LV10745A (lv) | Fungicida kompozicija | |
| MX9204200A (es) | Estabilizadores de bromato para las 3-izotiazolonas. | |
| ES428629A1 (es) | Procedimiento para la preparacion de derivados de adenosinadisustituidos n(6). | |
| DE3577705D1 (de) | Substituierte azolylcyclopropyl-azolylmethyl-carbinol-derivate. | |
| DE3271116D1 (de) | N-amido substituted dipeptides | |
| DK0594329T3 (da) | Antimikrobielle midler, der omfatter polykvaternære ammoniumforbindelser | |
| DE69213656D1 (de) | 1-Alkyl-2-Acyl-1,2-Disulfonylhydrazine mit antineoplastischer Aktivität | |
| DE69106298D1 (de) | 4,5-Polymethylen-4-isothiazolin-3-on-Derivate mit biocider Wirkung. | |
| ATE110384T1 (de) | Makrolid-derivate. | |
| ATE105565T1 (de) | Pradimicinderivate. | |
| ATE110383T1 (de) | Makrolid-derivate. | |
| DK0430471T3 (da) | Fungicider | |
| ATE90356T1 (de) | 21-alkoxy-steroid-derivate. | |
| ATE111446T1 (de) | Cyanoguanidin-derivate. | |
| ITMI922071A1 (it) | Derivati xantonici, loro preparazione ed attivita' | |
| TH2970A (th) | สารฆ่าวัชพืชไธโอฟีนซัลโฟแนมีดและพิริดีนซัลโฟแนมีด | |
| ATE100449T1 (de) | 1,3-dioxolan-benzoesaeure und derivate davon. |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |