ATE301715T1 - Durch molekulares pathogenicid vermittelte krankheitsresistenz in pflanzen - Google Patents
Durch molekulares pathogenicid vermittelte krankheitsresistenz in pflanzenInfo
- Publication number
- ATE301715T1 ATE301715T1 AT99970685T AT99970685T ATE301715T1 AT E301715 T1 ATE301715 T1 AT E301715T1 AT 99970685 T AT99970685 T AT 99970685T AT 99970685 T AT99970685 T AT 99970685T AT E301715 T1 ATE301715 T1 AT E301715T1
- Authority
- AT
- Austria
- Prior art keywords
- pathogen
- fusion proteins
- present
- pathogenicide
- molecular
- Prior art date
Links
- 208000035240 Disease Resistance Diseases 0.000 title 1
- 230000001404 mediated effect Effects 0.000 title 1
- 102000037865 fusion proteins Human genes 0.000 abstract 4
- 108020001507 fusion proteins Proteins 0.000 abstract 4
- 244000052769 pathogen Species 0.000 abstract 3
- 230000001717 pathogenic effect Effects 0.000 abstract 3
- 108091028043 Nucleic acid sequence Proteins 0.000 abstract 2
- 239000012528 membrane Substances 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- 238000004873 anchoring Methods 0.000 abstract 1
- 230000005540 biological transmission Effects 0.000 abstract 1
- 230000001413 cellular effect Effects 0.000 abstract 1
- 230000001627 detrimental effect Effects 0.000 abstract 1
- 230000004807 localization Effects 0.000 abstract 1
- 244000000003 plant pathogen Species 0.000 abstract 1
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
- 230000010076 replication Effects 0.000 abstract 1
- 230000008685 targeting Effects 0.000 abstract 1
- 231100000331 toxic Toxicity 0.000 abstract 1
- 230000002588 toxic effect Effects 0.000 abstract 1
- 239000013598 vector Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
- C12N15/8261—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield
- C12N15/8271—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance
- C12N15/8279—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance for biotic stress resistance, pathogen resistance, disease resistance
- C12N15/8283—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance for biotic stress resistance, pathogen resistance, disease resistance for virus resistance
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/21—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Pseudomonadaceae (F)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/415—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from plants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70503—Immunoglobulin superfamily
- C07K14/7051—T-cell receptor (TcR)-CD3 complex
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
- C07K16/10—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from RNA viruses
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
- C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
- C12N15/8257—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits for the production of primary gene products, e.g. pharmaceutical products, interferon
- C12N15/8258—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits for the production of primary gene products, e.g. pharmaceutical products, interferon for the production of oral vaccines (antigens) or immunoglobulins
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/10—Immunoglobulins specific features characterized by their source of isolation or production
- C07K2317/13—Immunoglobulins specific features characterized by their source of isolation or production isolated from plants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
- C07K2317/62—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
- C07K2317/622—Single chain antibody (scFv)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Genetics & Genomics (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biophysics (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Immunology (AREA)
- Zoology (AREA)
- Biomedical Technology (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Cell Biology (AREA)
- Virology (AREA)
- Gastroenterology & Hepatology (AREA)
- Plant Pathology (AREA)
- Microbiology (AREA)
- Physics & Mathematics (AREA)
- Botany (AREA)
- Toxicology (AREA)
- Pharmacology & Pharmacy (AREA)
- Peptides Or Proteins (AREA)
- Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP98119630 | 1998-10-16 | ||
IN666BO1998 | 1998-10-16 | ||
PCT/EP1999/007844 WO2000023593A2 (en) | 1998-10-16 | 1999-10-15 | Molecular pathogenicide mediated plant disease resistance |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE301715T1 true ATE301715T1 (de) | 2005-08-15 |
Family
ID=26149719
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT99970685T ATE301715T1 (de) | 1998-10-16 | 1999-10-15 | Durch molekulares pathogenicid vermittelte krankheitsresistenz in pflanzen |
Country Status (8)
Country | Link |
---|---|
US (1) | US6825325B1 (de) |
EP (1) | EP1123398B1 (de) |
AT (1) | ATE301715T1 (de) |
BR (1) | BR9915543A (de) |
CA (1) | CA2345903C (de) |
DE (1) | DE69926647T2 (de) |
ES (1) | ES2246093T3 (de) |
WO (1) | WO2000023593A2 (de) |
Families Citing this family (37)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2000025574A1 (en) * | 1998-10-30 | 2000-05-11 | Thomas Jefferson University | Production of biomedical peptides and proteins in plants using plant virus vectors |
US7696325B2 (en) | 1999-03-10 | 2010-04-13 | Chugai Seiyaku Kabushiki Kaisha | Polypeptide inducing apoptosis |
US20030143234A1 (en) * | 1999-08-20 | 2003-07-31 | Wenyuan Shi | Anti-microbial targeting chimeric pharmaceutical |
EP1092769B1 (de) * | 1999-10-15 | 2008-10-29 | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. | Polypeptid-Tag's für den Nachweis und die Aufreinigung von Polypeptiden |
DE19962583A1 (de) * | 1999-12-23 | 2001-06-28 | Mueller Hermelink Hans Konrad | Antikörper gegen Plasmazellen |
DE10003573A1 (de) * | 2000-01-27 | 2001-08-09 | Mpb Cologne Gmbh Molecular Pla | Hemmung von Kohlenhydrat-modifizierenden Enzymen in Wirtsorganismen |
GB0003284D0 (en) * | 2000-02-15 | 2000-04-05 | Secr Defence Brit | Anti-viral therapy |
US8034903B2 (en) | 2000-10-20 | 2011-10-11 | Chugai Seiyaku Kabushiki Kaisha | Degraded TPO agonist antibody |
MXPA03006454A (es) * | 2001-01-18 | 2004-02-12 | Icon Genetics Inc | Utilizacion de virus para detectar o purificar proteinas. |
US7390885B2 (en) * | 2001-11-26 | 2008-06-24 | Cell Matrix, Inc. | Humanized collagen antibodies and related methods |
US7365167B2 (en) | 2001-11-26 | 2008-04-29 | Cell Matrix, Inc. | Humanized collagen antibodies and related methods |
GB0128793D0 (en) * | 2001-11-30 | 2002-01-23 | Novartis Forschungsstiftung | Screening method for compounds that modulate neuronal activity |
CA2482607C (en) * | 2002-04-22 | 2013-06-11 | Fraunhofer-Gesellschaft Zur Foerderung Der Angewandten Forschung E.V. | Antibodies, recombinant antibodies, recombinant antibody fragments and fusions mediated plant disease resistance against fungi |
KR101239242B1 (ko) | 2002-08-02 | 2013-03-11 | 글락소스미스클라인 바이오로지칼즈 에스.에이. | 항원 조합물을 포함하는 나이세리아 백신 조성물 |
JP5348651B2 (ja) * | 2002-11-22 | 2013-11-20 | ネクスバイオ,インク. | 広域抗ウイルス治療および予防薬 |
EP2192172B1 (de) | 2003-02-03 | 2014-12-03 | iBio, Inc. | System zur Expression von Genen in Pflanzen |
JP2004279086A (ja) * | 2003-03-13 | 2004-10-07 | Konica Minolta Holdings Inc | 放射線画像変換パネル及び放射線画像変換パネルの製造方法 |
US8703134B2 (en) | 2003-05-15 | 2014-04-22 | Iogenetics, Llc | Targeted cryptosporidium biocides |
US7566447B2 (en) | 2003-05-15 | 2009-07-28 | Iogenetics, Llc | Biocides |
US8394379B2 (en) | 2003-05-15 | 2013-03-12 | Iogenetics, Llc | Targeted cryptosporidium biocides |
WO2006106903A1 (ja) | 2005-03-31 | 2006-10-12 | Chugai Seiyaku Kabushiki Kaisha | sc(Fv)2構造異性体 |
WO2006129843A2 (en) * | 2005-05-31 | 2006-12-07 | Canon Kabushiki Kaisha | Bispecific capturing molecule |
AU2006256041B2 (en) | 2005-06-10 | 2012-03-29 | Chugai Seiyaku Kabushiki Kaisha | Stabilizer for protein preparation comprising meglumine and use thereof |
US9241994B2 (en) | 2005-06-10 | 2016-01-26 | Chugai Seiyaku Kabushiki Kaisha | Pharmaceutical compositions containing sc(Fv)2 |
WO2008062310A2 (en) * | 2006-05-19 | 2008-05-29 | Hornedo Jose Luis Stephano | Elimination of the bacteria that cause pierce's disease |
US8859229B2 (en) * | 2007-02-02 | 2014-10-14 | Yale University | Transient transfection with RNA |
US10155038B2 (en) | 2007-02-02 | 2018-12-18 | Yale University | Cells prepared by transient transfection and methods of use thereof |
US9249423B2 (en) | 2007-02-02 | 2016-02-02 | Yale University | Method of de-differentiating and re-differentiating somatic cells using RNA |
EP2197903B9 (de) * | 2007-09-04 | 2015-04-22 | The Government of the United States of America as represented by the Secretary of the Department of Health and Human Services | Deletionen in der domäne ii von pseudomonas-exotoxin, die die nichtspezifische toxizität vermindern |
JO2913B1 (en) | 2008-02-20 | 2015-09-15 | امجين إنك, | Antibodies directed towards angiopoietin-1 and angiopoietin-2 proteins and their uses |
EP2258719A1 (de) * | 2009-05-19 | 2010-12-08 | Max-Delbrück-Centrum für Molekulare Medizin (MDC) | Mehrfachziel-T-Zellen-Rezeptor |
CA2754024A1 (en) | 2009-08-24 | 2011-03-03 | Sylvia Schleker | Antibody fusion-mediated plant resistance against oomycota |
CN102869377A (zh) | 2010-03-10 | 2013-01-09 | 葛兰素史密丝克莱恩生物有限公司 | 免疫原性组合物 |
US9217040B2 (en) | 2011-01-14 | 2015-12-22 | The Regents Of The University Of California | Therapeutic antibodies against ROR-1 protein and methods for use of same |
TR201819577T4 (tr) | 2013-04-29 | 2019-01-21 | Agrosavfe N V | Sfingolipitleri bağlayan antikorlar içeren agrokimyasal bileşimler. |
JP7089877B2 (ja) | 2014-11-05 | 2022-06-23 | バイオタリス・エン・フェー | 重鎖抗体の可変ドメインをコードするポリヌクレオチドを含むトランスジェニック植物 |
US10676723B2 (en) | 2015-05-11 | 2020-06-09 | David Gordon Bermudes | Chimeric protein toxins for expression by therapeutic bacteria |
Family Cites Families (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5374548A (en) * | 1986-05-02 | 1994-12-20 | Genentech, Inc. | Methods and compositions for the attachment of proteins to liposomes using a glycophospholipid anchor |
EP0479180A3 (en) * | 1990-10-05 | 1992-08-26 | Hoechst Aktiengesellschaft | Virus resistant plants, method for their production |
US5989886A (en) * | 1991-01-02 | 1999-11-23 | The Johns Hopkins University | Method for the inhibition and prevention of viral replication using fusions of a virus protein and a destructive enzyme |
US5866787A (en) * | 1993-03-08 | 1999-02-02 | Cleveland Clinic Foundation | Transgenic plants co-expressing a functional human 2-5A system |
GB9321469D0 (en) * | 1993-10-18 | 1993-12-08 | Zeneca Ltd | Insecticidal proteins |
US5686600A (en) * | 1994-06-28 | 1997-11-11 | Novartis Finance Corporation | Antibodies which bind to insect gut proteins and their use |
WO1996009398A1 (en) * | 1994-09-19 | 1996-03-28 | Rijkslandbouwuniversiteit Wageningen | Gene constructs encoding crop-protecting agents, as well as transformed plants containing and expressing such constructs, and methods of controlling plague organisms and pathogens in crops |
US5698679A (en) * | 1994-09-19 | 1997-12-16 | National Jewish Center For Immunology And Respiratory Medicine | Product and process for targeting an immune response |
US5876950A (en) * | 1995-01-26 | 1999-03-02 | Bristol-Myers Squibb Company | Monoclonal antibodies specific for different epitopes of human GP39 and methods for their use in diagnosis and therapy |
GB9520641D0 (en) * | 1995-10-10 | 1995-12-13 | Medical Res Council | Improvements in or relating to protection against intracellular infection |
CA2236036A1 (en) * | 1995-10-27 | 1998-01-29 | California Institute Of Technology | Signal-regulated, cleavage-mediated toxins |
AR020090A1 (es) * | 1998-06-15 | 2002-04-10 | John Innes Ct | Celula vegetal monocotiledonea o semilla de ella,planta o parte de una planta, metodo para hacer una celula vegetal monocotiledonea, metodo para hacer unaplanta, uso de una construccion de expresion para producir una celula de planta o semilla monocotiledonea, y uso de una construccion de expresion |
AU6137499A (en) * | 1998-09-03 | 2000-03-27 | Yong Ping Duan | Methods for controlling viral diseases in plants |
-
1999
- 1999-10-15 ES ES99970685T patent/ES2246093T3/es not_active Expired - Lifetime
- 1999-10-15 BR BR9915543-5A patent/BR9915543A/pt not_active IP Right Cessation
- 1999-10-15 WO PCT/EP1999/007844 patent/WO2000023593A2/en active IP Right Grant
- 1999-10-15 CA CA002345903A patent/CA2345903C/en not_active Expired - Fee Related
- 1999-10-15 EP EP99970685A patent/EP1123398B1/de not_active Expired - Lifetime
- 1999-10-15 DE DE69926647T patent/DE69926647T2/de not_active Expired - Lifetime
- 1999-10-15 AT AT99970685T patent/ATE301715T1/de not_active IP Right Cessation
- 1999-10-18 US US09/419,788 patent/US6825325B1/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
WO2000023593A2 (en) | 2000-04-27 |
ES2246093T3 (es) | 2006-02-01 |
DE69926647T2 (de) | 2006-11-09 |
BR9915543A (pt) | 2001-08-14 |
EP1123398B1 (de) | 2005-08-10 |
DE69926647D1 (de) | 2005-09-15 |
US6825325B1 (en) | 2004-11-30 |
WO2000023593A3 (en) | 2000-07-27 |
EP1123398A2 (de) | 2001-08-16 |
CA2345903A1 (en) | 2000-04-27 |
CA2345903C (en) | 2006-09-26 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |