WO2001074854A3 - 32449, a putative human transporter and uses thereof - Google Patents

32449, a putative human transporter and uses thereof Download PDF

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Publication number
WO2001074854A3
WO2001074854A3 PCT/US2001/010395 US0110395W WO0174854A3 WO 2001074854 A3 WO2001074854 A3 WO 2001074854A3 US 0110395 W US0110395 W US 0110395W WO 0174854 A3 WO0174854 A3 WO 0174854A3
Authority
WO
WIPO (PCT)
Prior art keywords
mtp
nucleic acid
acid molecules
expression vectors
provides isolated
Prior art date
Application number
PCT/US2001/010395
Other languages
French (fr)
Other versions
WO2001074854A2 (en
Inventor
Maria Alexandra Glucksmann
Original Assignee
Millennium Pharm Inc
Maria Alexandra Glucksmann
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Millennium Pharm Inc, Maria Alexandra Glucksmann filed Critical Millennium Pharm Inc
Priority to AU2001249697A priority Critical patent/AU2001249697A1/en
Publication of WO2001074854A2 publication Critical patent/WO2001074854A2/en
Publication of WO2001074854A3 publication Critical patent/WO2001074854A3/en

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

The invention provides isolated nucleic acid molecules, designated MTP nucleic acid molecules, which encode novel MTP-related transporter molecules. The invention also provides antisense nucleic acid molecules, recombinant expression vectors containing MTP nucleic acid molecules, host cells into which the expression vectors have been introduced, and nonhuman transgenic animals in which an MTP gene has been introduced or disrupted. The invention still further provides isolated MTP proteins, fusion proteins, antigenic peptides and anti-MTP antibodies. Diagnostic methods utilizing compositions of the invention are also provided.
PCT/US2001/010395 2000-03-31 2001-03-30 32449, a putative human transporter and uses thereof WO2001074854A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2001249697A AU2001249697A1 (en) 2000-03-31 2001-03-30 32449, a novel human transporter and uses thereof

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US19354900P 2000-03-31 2000-03-31
US60/193,549 2000-03-31

Publications (2)

Publication Number Publication Date
WO2001074854A2 WO2001074854A2 (en) 2001-10-11
WO2001074854A3 true WO2001074854A3 (en) 2002-05-30

Family

ID=22714081

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2001/010395 WO2001074854A2 (en) 2000-03-31 2001-03-30 32449, a putative human transporter and uses thereof

Country Status (2)

Country Link
AU (1) AU2001249697A1 (en)
WO (1) WO2001074854A2 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020064821A1 (en) * 2000-07-05 2002-05-30 Merkulov Gennady V. Isolated human ion channel proteins, nucleic acid molecules encoding human ion channel proteins, and uses thereof
US20020115136A1 (en) * 2001-02-07 2002-08-22 Gennady Merkulov Isolated human transporter proteins, nucleic acid molecules encoding human transporter proteins, and uses thereof

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999055865A1 (en) * 1998-04-29 1999-11-04 Genesis Research And Development Corporation Limited Polynucleotides isolated from skin cells and methods for their use
WO2000061614A2 (en) * 1999-04-09 2000-10-19 Human Genome Sciences, Inc. Uncoupling proteins
WO2001016318A2 (en) * 1999-09-01 2001-03-08 Genentech, Inc. Secreted and transmembrane polypeptides and nucleic acids encoding the same

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999055865A1 (en) * 1998-04-29 1999-11-04 Genesis Research And Development Corporation Limited Polynucleotides isolated from skin cells and methods for their use
WO2000061614A2 (en) * 1999-04-09 2000-10-19 Human Genome Sciences, Inc. Uncoupling proteins
WO2001016318A2 (en) * 1999-09-01 2001-03-08 Genentech, Inc. Secreted and transmembrane polypeptides and nucleic acids encoding the same

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
DATABASE EMBL 1 February 2000 (2000-02-01), B. BIERY ET AL.: "HOMO SAPIENS CALCIUM-BINDING TRANSPORTER mRNA", XP002186856 *
DATABASE EMBL 11 September 1997 (1997-09-11), F. E. WEBER ET AL.: "ORYCTOLAGUS CUNICULUS PEROXISOMAL CA-DEPENDENT SOLUTE CARRIER mRNA", XP002186854 *
DATABASE EMBL 8 October 1999 (1999-10-08), DOE JOINT GENOME INSTITUTE: "HOMO SAPIENS CHROMOSOME 19 CLONE LLNLR-253C9", XP002186857 *
DATABASE SWISSPROT 1 May 1999 (1999-05-01), U. A RINK ET AL.: "MITOCHONDRIAL ENERGY TRANSFER PROTEIN PRECURSOR (BRITTLE1)", XP002186855 *
F. E. WEBER ET AL.: "MOLECULAR CLONING OF A PEROXISOMAL Ca2+-DEPENDENT MEMBER OF THE MITOCHONDRIAL CARRIER SUPERFAMILY", PROC. NATL. ACAD. SCI. USA, vol. 94, August 1997 (1997-08-01), pages 8509 - 8514, XP002188067 *

Also Published As

Publication number Publication date
WO2001074854A2 (en) 2001-10-11
AU2001249697A1 (en) 2001-10-15

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