ATE298420T1 - Mehrschichtenmembranen für enzymelektrode und verfahren zu ihrer herstellung - Google Patents

Mehrschichtenmembranen für enzymelektrode und verfahren zu ihrer herstellung

Info

Publication number
ATE298420T1
ATE298420T1 AT97928393T AT97928393T ATE298420T1 AT E298420 T1 ATE298420 T1 AT E298420T1 AT 97928393 T AT97928393 T AT 97928393T AT 97928393 T AT97928393 T AT 97928393T AT E298420 T1 ATE298420 T1 AT E298420T1
Authority
AT
Austria
Prior art keywords
sensor
layer
sample solution
electrode membrane
enzyme
Prior art date
Application number
AT97928393T
Other languages
English (en)
Inventor
Robert Mccaffrey
Bonnie Dalzell
Katarina Tkacik
Susan Holbert
Mark Boden
James Flaherty
Michael Flanagan
Josef Brown
Kimiya Takeshita
Peter Edelman
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag filed Critical Bayer Ag
Application granted granted Critical
Publication of ATE298420T1 publication Critical patent/ATE298420T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/001—Enzyme electrodes
    • C12Q1/002—Electrode membranes
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/817—Enzyme or microbe electrode

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Inert Electrodes (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
AT97928393T 1996-07-12 1997-07-11 Mehrschichtenmembranen für enzymelektrode und verfahren zu ihrer herstellung ATE298420T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/679,089 US5696314A (en) 1996-07-12 1996-07-12 Multilayer enzyme electrode membranes and methods of making same
PCT/IB1997/000861 WO1998002736A1 (en) 1996-07-12 1997-07-11 Multilayer enzyme electrode membranes and methods of making same

Publications (1)

Publication Number Publication Date
ATE298420T1 true ATE298420T1 (de) 2005-07-15

Family

ID=24725520

Family Applications (1)

Application Number Title Priority Date Filing Date
AT97928393T ATE298420T1 (de) 1996-07-12 1997-07-11 Mehrschichtenmembranen für enzymelektrode und verfahren zu ihrer herstellung

Country Status (9)

Country Link
US (1) US5696314A (de)
EP (1) EP0910794B1 (de)
JP (1) JP2001506742A (de)
AT (1) ATE298420T1 (de)
AU (1) AU3270797A (de)
DE (1) DE69733608T2 (de)
DK (1) DK0910794T3 (de)
ES (1) ES2245000T3 (de)
WO (1) WO1998002736A1 (de)

Families Citing this family (81)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5593852A (en) 1993-12-02 1997-01-14 Heller; Adam Subcutaneous glucose electrode
US7899511B2 (en) 2004-07-13 2011-03-01 Dexcom, Inc. Low oxygen in vivo analyte sensor
US6030827A (en) * 1998-01-23 2000-02-29 I-Stat Corporation Microfabricated aperture-based sensor
US6134461A (en) 1998-03-04 2000-10-17 E. Heller & Company Electrochemical analyte
US8688188B2 (en) 1998-04-30 2014-04-01 Abbott Diabetes Care Inc. Analyte monitoring device and methods of use
US8346337B2 (en) 1998-04-30 2013-01-01 Abbott Diabetes Care Inc. Analyte monitoring device and methods of use
US8480580B2 (en) 1998-04-30 2013-07-09 Abbott Diabetes Care Inc. Analyte monitoring device and methods of use
US8974386B2 (en) 1998-04-30 2015-03-10 Abbott Diabetes Care Inc. Analyte monitoring device and methods of use
US6175752B1 (en) 1998-04-30 2001-01-16 Therasense, Inc. Analyte monitoring device and methods of use
US8465425B2 (en) 1998-04-30 2013-06-18 Abbott Diabetes Care Inc. Analyte monitoring device and methods of use
US6949816B2 (en) 2003-04-21 2005-09-27 Motorola, Inc. Semiconductor component having first surface area for electrically coupling to a semiconductor chip and second surface area for electrically coupling to a substrate, and method of manufacturing same
US9066695B2 (en) 1998-04-30 2015-06-30 Abbott Diabetes Care Inc. Analyte monitoring device and methods of use
EP0969282B1 (de) * 1998-07-02 2011-09-21 NEC Corporation Eine Enzymelektrode, ein Biosensor und ein Messapparat dafür
EP1039291A1 (de) * 1999-03-26 2000-09-27 Sony International (Europe) GmbH Optochemischer Fühler and Herstellungsmethode
AU2001263022A1 (en) 2000-05-12 2001-11-26 Therasense, Inc. Electrodes with multilayer membranes and methods of using and making the electrodes
ATE278956T1 (de) * 2000-07-27 2004-10-15 Micronas Holding Gmbh Sensor-chips mit polysiloxan-mehrfachschichten
JP3713522B2 (ja) * 2000-10-27 2005-11-09 アークレイ株式会社 バイオセンサ
US6560471B1 (en) 2001-01-02 2003-05-06 Therasense, Inc. Analyte monitoring device and methods of use
US6932894B2 (en) * 2001-05-15 2005-08-23 Therasense, Inc. Biosensor membranes composed of polymers containing heterocyclic nitrogens
JP4167595B2 (ja) * 2001-07-24 2008-10-15 日本電気株式会社 酵素電極およびその製造方法
US7323142B2 (en) * 2001-09-07 2008-01-29 Medtronic Minimed, Inc. Sensor substrate and method of fabricating same
US7025760B2 (en) * 2001-09-07 2006-04-11 Medtronic Minimed, Inc. Method and system for non-vascular sensor implantation
US6671554B2 (en) 2001-09-07 2003-12-30 Medtronic Minimed, Inc. Electronic lead for a medical implant device, method of making same, and method and apparatus for inserting same
US6915147B2 (en) 2001-09-07 2005-07-05 Medtronic Minimed, Inc. Sensing apparatus and process
US8506550B2 (en) * 2001-09-07 2013-08-13 Medtronic Minimed, Inc. Method and system for non-vascular sensor implantation
US8465466B2 (en) 2001-10-23 2013-06-18 Medtronic Minimed, Inc Method and system for non-vascular sensor implantation
US7192766B2 (en) * 2001-10-23 2007-03-20 Medtronic Minimed, Inc. Sensor containing molded solidified protein
US6809507B2 (en) 2001-10-23 2004-10-26 Medtronic Minimed, Inc. Implantable sensor electrodes and electronic circuitry
US20040137547A1 (en) * 2001-12-28 2004-07-15 Medtronic Minimed, Inc. Method for formulating a glucose oxidase enzyme with a desired property or properties and a glucose oxidase enzyme with the desired property
US9247901B2 (en) 2003-08-22 2016-02-02 Dexcom, Inc. Systems and methods for replacing signal artifacts in a glucose sensor data stream
US8260393B2 (en) 2003-07-25 2012-09-04 Dexcom, Inc. Systems and methods for replacing signal data artifacts in a glucose sensor data stream
US8010174B2 (en) 2003-08-22 2011-08-30 Dexcom, Inc. Systems and methods for replacing signal artifacts in a glucose sensor data stream
US20070227907A1 (en) * 2006-04-04 2007-10-04 Rajiv Shah Methods and materials for controlling the electrochemistry of analyte sensors
US7162289B2 (en) * 2002-09-27 2007-01-09 Medtronic Minimed, Inc. Method and apparatus for enhancing the integrity of an implantable sensor device
US7736309B2 (en) * 2002-09-27 2010-06-15 Medtronic Minimed, Inc. Implantable sensor method and system
US20050272989A1 (en) * 2004-06-04 2005-12-08 Medtronic Minimed, Inc. Analyte sensors and methods for making and using them
US20040074785A1 (en) * 2002-10-18 2004-04-22 Holker James D. Analyte sensors and methods for making them
US9237865B2 (en) * 2002-10-18 2016-01-19 Medtronic Minimed, Inc. Analyte sensors and methods for making and using them
US8060173B2 (en) 2003-08-01 2011-11-15 Dexcom, Inc. System and methods for processing analyte sensor data
US7591801B2 (en) 2004-02-26 2009-09-22 Dexcom, Inc. Integrated delivery device for continuous glucose sensor
US7920906B2 (en) 2005-03-10 2011-04-05 Dexcom, Inc. System and methods for processing analyte sensor data for sensor calibration
US20140121989A1 (en) 2003-08-22 2014-05-01 Dexcom, Inc. Systems and methods for processing analyte sensor data
JP2007514460A (ja) * 2003-09-30 2007-06-07 エフ ホフマン−ラ ロッシュ アクチェン ゲゼルシャフト 増大した生物適合性を示すセンサー
US8414489B2 (en) * 2003-11-13 2013-04-09 Medtronic Minimed, Inc. Fabrication of multi-sensor arrays
US9247900B2 (en) 2004-07-13 2016-02-02 Dexcom, Inc. Analyte sensor
WO2005051170A2 (en) 2003-11-19 2005-06-09 Dexcom, Inc. Integrated receiver for continuous analyte sensor
US8615282B2 (en) 2004-07-13 2013-12-24 Dexcom, Inc. Analyte sensor
US8423114B2 (en) 2006-10-04 2013-04-16 Dexcom, Inc. Dual electrode system for a continuous analyte sensor
US11633133B2 (en) 2003-12-05 2023-04-25 Dexcom, Inc. Dual electrode system for a continuous analyte sensor
EP2239566B1 (de) 2003-12-05 2014-04-23 DexCom, Inc. Kalibrierverfahren für einen kontinuierlichen Analytsensor
RU2004103056A (ru) * 2004-02-05 2005-07-10 Сергей Владимирович Синицын (BY) Способ воздействия на молекулу, способ управления ферментативным катализом и устройство захвата и изменения молекулы
US7807043B2 (en) * 2004-02-23 2010-10-05 Oakville Hong Kong Company Limited Microfluidic test device
WO2009048462A1 (en) 2007-10-09 2009-04-16 Dexcom, Inc. Integrated insulin delivery system with continuous glucose sensor
US8808228B2 (en) 2004-02-26 2014-08-19 Dexcom, Inc. Integrated medicament delivery device for use with continuous analyte sensor
US20060013731A1 (en) * 2004-03-26 2006-01-19 Phil Stout Microfluidic system with feedback control
US20050266571A1 (en) * 2004-03-26 2005-12-01 Phil Stout Method for feedback control of a microfluidic system
US8792955B2 (en) 2004-05-03 2014-07-29 Dexcom, Inc. Transcutaneous analyte sensor
WO2005121759A2 (en) * 2004-05-24 2005-12-22 Albatros Technologies Gmbh & Co. Kg Device and method for analyte measurement
US7905833B2 (en) 2004-07-13 2011-03-15 Dexcom, Inc. Transcutaneous analyte sensor
US8565848B2 (en) 2004-07-13 2013-10-22 Dexcom, Inc. Transcutaneous analyte sensor
WO2006127694A2 (en) 2004-07-13 2006-11-30 Dexcom, Inc. Analyte sensor
US20060020192A1 (en) 2004-07-13 2006-01-26 Dexcom, Inc. Transcutaneous analyte sensor
CN103305590A (zh) * 2004-12-13 2013-09-18 拜尔保健有限公司 用于测量生物液体中的分析物的自我限定大小的组合物和检验设备
WO2006064342A2 (en) * 2004-12-14 2006-06-22 Nissan Motor Co., Ltd. Electrode for use in a battery and method of making the same
US8133178B2 (en) 2006-02-22 2012-03-13 Dexcom, Inc. Analyte sensor
US20060249542A1 (en) * 2005-04-26 2006-11-09 Allen Randall E Dispensing device for materials, method and system of use thereof
US7725148B2 (en) 2005-09-23 2010-05-25 Medtronic Minimed, Inc. Sensor with layered electrodes
US9757061B2 (en) 2006-01-17 2017-09-12 Dexcom, Inc. Low oxygen in vivo analyte sensor
US20080306434A1 (en) 2007-06-08 2008-12-11 Dexcom, Inc. Integrated medicament delivery device for use with continuous analyte sensor
US20100025238A1 (en) * 2008-07-31 2010-02-04 Medtronic Minimed, Inc. Analyte sensor apparatuses having improved electrode configurations and methods for making and using them
US8700114B2 (en) * 2008-07-31 2014-04-15 Medtronic Minmed, Inc. Analyte sensor apparatuses comprising multiple implantable sensor elements and methods for making and using them
US8900431B2 (en) 2008-08-27 2014-12-02 Edwards Lifesciences Corporation Analyte sensor
US8660628B2 (en) * 2009-12-21 2014-02-25 Medtronic Minimed, Inc. Analyte sensors comprising blended membrane compositions and methods for making and using them
WO2014110492A2 (en) * 2013-01-11 2014-07-17 Northeastern University Saliva glucose monitoring system
EP3380833B1 (de) * 2015-11-27 2019-12-25 Radiometer Medical ApS Aussenschicht für enzymsensoren
JP7068327B2 (ja) * 2017-03-03 2022-05-16 シーメンス・ヘルスケア・ダイアグノスティックス・インコーポレーテッド ナノビーズを含むバイオセンサーの製造方法及びその使用
US11331022B2 (en) 2017-10-24 2022-05-17 Dexcom, Inc. Pre-connected analyte sensors
US11382540B2 (en) 2017-10-24 2022-07-12 Dexcom, Inc. Pre-connected analyte sensors
US11109784B2 (en) * 2018-04-09 2021-09-07 California Institute Of Technology Metal-enzyme sandwich layers
JP7410158B2 (ja) * 2019-01-28 2024-01-09 アボット ダイアベティス ケア インコーポレイテッド 複数の酵素を用いた分析物センサ
CN114660140B (zh) * 2020-12-23 2024-02-23 北京京东方技术开发有限公司 生物检测装置、生物芯片、微电极结构及其制备方法

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3661011A (en) * 1970-03-02 1972-05-09 Melabs Inc High-speed microvolume membrane osmometry
US3635075A (en) * 1970-06-29 1972-01-18 Beckman Instruments Inc Osmometer
US3756923A (en) * 1970-11-30 1973-09-04 H Dahms Method of determining so2 concentration
US4238757A (en) * 1976-03-19 1980-12-09 General Electric Company Field effect transistor for detection of biological reactions
US4267023A (en) * 1977-10-17 1981-05-12 Orion Research Incorporated Chemically integrating dosimeter and gas analysis methods
US4311669A (en) * 1980-08-21 1982-01-19 The Bendix Corporation Membrane interface for ion mobility detector cells
JPS57208997A (en) * 1981-06-17 1982-12-22 Fuji Photo Film Co Ltd Liquid analyzing material for oxidase enzyme reaction system
JPS61281960A (ja) * 1985-06-07 1986-12-12 Kirin Brewery Co Ltd ハイブリッド酵素膜アルコ−ルセンサ−
GB8612861D0 (en) * 1986-05-27 1986-07-02 Cambridge Life Sciences Immobilised enzyme biosensors
GB8817997D0 (en) * 1988-07-28 1988-09-01 Cambridge Life Sciences Enzyme electrodes & improvements in manufacture thereof
US5438984A (en) * 1988-09-08 1995-08-08 Sudor Partners Apparatus and method for the collection of analytes on a dermal patch
US5200051A (en) * 1988-11-14 1993-04-06 I-Stat Corporation Wholly microfabricated biosensors and process for the manufacture and use thereof
US5212050A (en) * 1988-11-14 1993-05-18 Mier Randall M Method of forming a permselective layer
JPH04212050A (ja) * 1990-05-29 1992-08-03 Matsushita Electric Ind Co Ltd バイオセンサおよびその製造法
JP2786336B2 (ja) * 1991-03-04 1998-08-13 富士写真フイルム株式会社 免疫分析要素および免疫分析方法
AU3274693A (en) * 1991-12-31 1993-07-28 Abbott Laboratories Composite membrane
JP2550463B2 (ja) * 1992-09-25 1996-11-06 株式会社エー・アンド・デイ 酵素電極
US5494562A (en) * 1994-06-27 1996-02-27 Ciba Corning Diagnostics Corp. Electrochemical sensors
US5520788A (en) * 1995-01-17 1996-05-28 The Yellow Springs Instrument Company, Inc. Support layer for enzyme electrode laminated membranes
EP0771867A3 (de) * 1995-10-30 1998-09-02 Ciba-Geigy Japan Limited Enzymelektrode
DE69634802T2 (de) * 1995-11-08 2006-03-16 Hypoguard Ltd., Woodbridge Biosensoren mit membran

Also Published As

Publication number Publication date
DK0910794T3 (da) 2005-09-19
DE69733608T2 (de) 2006-05-11
JP2001506742A (ja) 2001-05-22
WO1998002736A1 (en) 1998-01-22
US5696314A (en) 1997-12-09
EP0910794A1 (de) 1999-04-28
AU3270797A (en) 1998-02-09
DE69733608D1 (de) 2005-07-28
ES2245000T3 (es) 2005-12-16
EP0910794B1 (de) 2005-06-22

Similar Documents

Publication Publication Date Title
ATE298420T1 (de) Mehrschichtenmembranen für enzymelektrode und verfahren zu ihrer herstellung
Do et al. Microbial fuel cell-based biosensor for online monitoring wastewater quality: a critical review
US5916156A (en) Electrochemical sensors having improved selectivity and enhanced sensitivity
AU605111B2 (en) Enzyme-electrode sensor
US4356074A (en) Substrate specific galactose oxidase enzyme electrodes
CA2072885C (en) Polarographic chemical sensor with external reference electrode
Fraiwan et al. Bacteria-powered battery on paper
Abass et al. Development of an amperometric sulfite biosensor based on sulfite oxidase with cytochrome c, as electron acceptor, and a screen-printed transducer
JPH0418626B2 (de)
JPH0777511A (ja) ガス測定用バイオセンサー及びその製造方法
Wang et al. Study on the kinetics of homogeneous enzyme reactions in a micro/nanofluidics device
CN107884462B (zh) 生物传感器、其制造方法、葡萄糖或乳酸的浓度测定方法和浓度测定系统
JPH0136062B2 (de)
DE2638193C3 (de) Laminierte Membran für die Verwendung in einer Enzymelektrode und Verfahren zur Herstellung einer solchen Membran
EP1271143A4 (de) Muster, das die kapazität hat, solide komponenten zu separieren
AU662895B2 (en) Sensor devices
US4859306A (en) Selectively ion-permeable dry electrodes for analyzing selected ions in aqueous solution
JPS60185153A (ja) 固定化酵素膜
JP2007003280A (ja) 電極構造体及びそれを含む体液中のリン酸測定用酵素センサー
JP2977258B2 (ja) バイオセンサ
JP2010060375A (ja) 電気化学測定装置用電極およびバイオセンサ用電極
AU671253B2 (en) Solid state ion sensor with polyurethane membrane
KR0161954B1 (ko) 전기화학식 면역 바이오센서
ATE161054T1 (de) Analytisches verfahren und vorrichtung zur bestimmung von hydrogen peroxid
Metelka et al. Carbon paste electrode containing dispersed bismuth powder for pH measurements

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification

Ref document number: 0910794

Country of ref document: EP

REN Ceased due to non-payment of the annual fee