ATE294179T1 - Synthese acyclischer nucleosid-derivate - Google Patents

Synthese acyclischer nucleosid-derivate

Info

Publication number
ATE294179T1
ATE294179T1 AT99948005T AT99948005T ATE294179T1 AT E294179 T1 ATE294179 T1 AT E294179T1 AT 99948005 T AT99948005 T AT 99948005T AT 99948005 T AT99948005 T AT 99948005T AT E294179 T1 ATE294179 T1 AT E294179T1
Authority
AT
Austria
Prior art keywords
chem
compound
formula
synthesis
nucleoside derivatives
Prior art date
Application number
AT99948005T
Other languages
English (en)
Inventor
M Robert Leanna
Steven M Hannick
Michael Rasmussen
Jien-Heh J Tien
Lakshmi Bhagavatula
Pulla Reddy Singam
Bradley D Gates
Lawrence Kolaczkowski
Ramesh R Patel
Greg Wayne
Greg Lannoye
Weijiang Zhang
Kirill A Lukin
Bikshandarkor Narayanan
David A Riley
Howard Morton
Sou-Jen Chang
Cynthia B Curty
Daniel Plata
John Bellettini
Bhadra Shellat
Tiffany Spitz
Cheng-Xi Yang
Zhenping Tian
Original Assignee
Medivir Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Medivir Ab filed Critical Medivir Ab
Application granted granted Critical
Publication of ATE294179T1 publication Critical patent/ATE294179T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D473/00Heterocyclic compounds containing purine ring systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C309/00Sulfonic acids; Halides, esters, or anhydrides thereof
    • C07C309/63Esters of sulfonic acids
    • C07C309/72Esters of sulfonic acids having sulfur atoms of esterified sulfo groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
    • C07C309/73Esters of sulfonic acids having sulfur atoms of esterified sulfo groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton to carbon atoms of non-condensed six-membered aromatic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D473/00Heterocyclic compounds containing purine ring systems
    • C07D473/02Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C07D473/18Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 one oxygen and one nitrogen atom, e.g. guanine
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
AT99948005T 1998-08-06 1999-08-05 Synthese acyclischer nucleosid-derivate ATE294179T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/130,214 US6184376B1 (en) 1997-02-10 1998-08-06 Synthesis of acyclic nucleoside derivatives
PCT/SE1999/001339 WO2000008025A1 (en) 1998-08-06 1999-08-05 Synthesis of acyclic nucleoside derivatives

Publications (1)

Publication Number Publication Date
ATE294179T1 true ATE294179T1 (de) 2005-05-15

Family

ID=22443606

Family Applications (1)

Application Number Title Priority Date Filing Date
AT99948005T ATE294179T1 (de) 1998-08-06 1999-08-05 Synthese acyclischer nucleosid-derivate

Country Status (10)

Country Link
US (5) US6184376B1 (de)
EP (2) EP1535923A1 (de)
JP (1) JP2002522439A (de)
AT (1) ATE294179T1 (de)
AU (1) AU765286B2 (de)
CA (1) CA2339250C (de)
DE (1) DE69925023T2 (de)
ES (1) ES2237942T3 (de)
IL (2) IL141161A0 (de)
WO (1) WO2000008025A1 (de)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AUPQ806700A0 (en) * 2000-06-08 2000-07-06 Commonwealth Scientific And Industrial Research Organisation Antiviral agents
SE0102273D0 (sv) * 2001-06-26 2001-06-26 Medivir Ab Improved synthesis of branched acyclic nucleosides
DE60321457D1 (de) * 2002-04-08 2008-07-17 Sumitomo Chemical Co Kristall und solvat von 2-amino-6-benzyloxypurin und produktionsverfahren dafür
ATE518875T1 (de) * 2002-06-13 2011-08-15 Oreal Glucose und vitamin f derivate, zusammensetzungen derselben und ihre verwendung zur verbesserung des zustands von haaren
TWI332507B (en) * 2002-11-19 2010-11-01 Hoffmann La Roche Antiviral nucleoside derivatives
CN1742018A (zh) * 2002-12-10 2006-03-01 弗·哈夫曼-拉罗切有限公司 抗病毒的核苷衍生物
US20080233053A1 (en) * 2005-02-07 2008-09-25 Pharmalight Inc. Method and Device for Ophthalmic Administration of Active Pharmaceutical Ingredients
FR2914920B1 (fr) * 2007-04-11 2011-09-09 Clariant Specialty Fine Chem F Procede de deacetalisation d'alpha-aminoacetals.
CA2700227A1 (en) 2007-09-21 2009-04-02 Epiphany Biosciences, Inc. Valomaciclovir polymorphs
US7939336B2 (en) * 2008-09-30 2011-05-10 Calera Corporation Compositions and methods using substances containing carbon
WO2014047562A2 (en) * 2012-09-21 2014-03-27 Epiphany Biosciences Method of treating and/or preventing shingles and method of treating and/or preventing zoster associated pain
US11408892B2 (en) 2013-06-18 2022-08-09 The Trustees Of Columbia University In The City Of New York Devices, compositions and methods for imaging with raman scattering
WO2014205074A2 (en) * 2013-06-18 2014-12-24 The Trustees Of Columbia University In The City Of New York Devices, compositions and methods for imaging with raman scattering
WO2016044000A1 (en) * 2014-09-15 2016-03-24 Elevance Renewable Sciences, Inc. Low-toxicity olefinic ester compositions and methods of using the same

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5284837A (en) 1988-05-06 1994-02-08 Medivir Ab Derivatives of purine, process for their preparation and a pharmaceutical preparation
SE8801729D0 (sv) 1988-05-06 1988-05-06 Astra Ab Purine derivatives for use in therapy
US5216141A (en) 1988-06-06 1993-06-01 Benner Steven A Oligonucleotide analogs containing sulfur linkages
US5874578A (en) 1992-07-13 1999-02-23 Bristol-Myers Squibb Process for preparing guanine-containing antiviral agents and purinyl salts useful in such process
US5298651A (en) * 1992-10-15 1994-03-29 Monsanto Company Process for preparing isocyanates using phosphazine catalysts
WO1995022330A1 (en) 1994-02-17 1995-08-24 Commonwealth Scientific And Industrial Research Organisation Antiviral agents
PE32296A1 (es) 1994-07-28 1996-08-07 Hoffmann La Roche Ester de l-monovalina derivado de 2-(2-amino-1,6-dihidro-6-oxo-purin-9-il) metoxi-1,3-propandiol y sus sales farmaceuticamente aceptables
JP3906488B2 (ja) 1995-02-21 2007-04-18 味の素株式会社 プリン誘導体の製造方法
US5869493A (en) 1996-02-16 1999-02-09 Medivir Ab Acyclic nucleoside derivatives
EP0827960A1 (de) 1996-09-10 1998-03-11 Ajinomoto Co., Inc. Verfahren zur Herstellung von Purinderivaten
EP0971923B1 (de) * 1997-02-10 2002-11-06 Medivir Ab Verfahren zur herstellung von azyklischen nukleosiden

Also Published As

Publication number Publication date
US20040248910A1 (en) 2004-12-09
US7189849B2 (en) 2007-03-13
US20050250795A1 (en) 2005-11-10
US6613936B1 (en) 2003-09-02
AU765286B2 (en) 2003-09-11
DE69925023D1 (en) 2005-06-02
CA2339250C (en) 2008-07-15
US6184376B1 (en) 2001-02-06
IL141161A0 (en) 2002-02-10
EP1535923A1 (de) 2005-06-01
JP2002522439A (ja) 2002-07-23
ES2237942T3 (es) 2005-08-01
CA2339250A1 (en) 2000-02-17
EP1131323A1 (de) 2001-09-12
IL141161A (en) 2007-07-24
WO2000008025A1 (en) 2000-02-17
AU6127199A (en) 2000-02-28
DE69925023T2 (de) 2006-03-09
US20040024214A1 (en) 2004-02-05
EP1131323B1 (de) 2005-04-27
US6878844B2 (en) 2005-04-12

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