ATE291899T1 - Screening-verfahren mit hohem durchsatz (hts) unter verwendung von labormühlen oder microfluidics - Google Patents

Screening-verfahren mit hohem durchsatz (hts) unter verwendung von labormühlen oder microfluidics

Info

Publication number
ATE291899T1
ATE291899T1 AT02756105T AT02756105T ATE291899T1 AT E291899 T1 ATE291899 T1 AT E291899T1 AT 02756105 T AT02756105 T AT 02756105T AT 02756105 T AT02756105 T AT 02756105T AT E291899 T1 ATE291899 T1 AT E291899T1
Authority
AT
Austria
Prior art keywords
hts
particle size
compound
microfluidics
high throughput
Prior art date
Application number
AT02756105T
Other languages
English (en)
Inventor
Marie Lindner
Elaine Merisko-Liversidge
Greta Cary
Original Assignee
Marie Lindner
Elan Pharma Int Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Marie Lindner, Elan Pharma Int Ltd filed Critical Marie Lindner
Application granted granted Critical
Publication of ATE291899T1 publication Critical patent/ATE291899T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/145—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00—Screening for compounds of potential therapeutic value

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
AT02756105T 2001-06-22 2002-06-24 Screening-verfahren mit hohem durchsatz (hts) unter verwendung von labormühlen oder microfluidics ATE291899T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US29973301P 2001-06-22 2001-06-22
US33009301P 2001-10-19 2001-10-19
PCT/US2002/016589 WO2003000228A2 (en) 2001-06-22 2002-06-24 Method for high through put screening using a small scale mill or microfluidics

Publications (1)

Publication Number Publication Date
ATE291899T1 true ATE291899T1 (de) 2005-04-15

Family

ID=26971379

Family Applications (1)

Application Number Title Priority Date Filing Date
AT02756105T ATE291899T1 (de) 2001-06-22 2002-06-24 Screening-verfahren mit hohem durchsatz (hts) unter verwendung von labormühlen oder microfluidics

Country Status (8)

Country Link
US (1) US20030087308A1 (de)
EP (1) EP1401401B1 (de)
JP (1) JP2005504266A (de)
AT (1) ATE291899T1 (de)
AU (1) AU2002322019A1 (de)
CA (1) CA2451161A1 (de)
DE (1) DE60203506T2 (de)
WO (1) WO2003000228A2 (de)

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JP2011520779A (ja) * 2008-03-21 2011-07-21 エラン・ファルマ・インターナショナル・リミテッド イマチニブの部位特異的送達のための組成物および使用の方法
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CA2759125C (en) 2009-04-24 2017-08-15 Iceutica Pty Ltd A novel formulation of indomethacin
CA2763456C (en) 2009-05-27 2017-10-24 Alkermes Pharma Ireland Limited Reduction of flake-like aggregation in nanoparticulate active agent compositions
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US9334200B2 (en) 2013-01-28 2016-05-10 Bfp Management, Llc Fertilizer composition and method for suspending fertilizer in an aqueous solution
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Also Published As

Publication number Publication date
DE60203506T2 (de) 2006-02-16
EP1401401A2 (de) 2004-03-31
EP1401401B1 (de) 2005-03-30
DE60203506D1 (de) 2005-05-04
AU2002322019A1 (en) 2003-01-08
JP2005504266A (ja) 2005-02-10
CA2451161A1 (en) 2003-01-03
US20030087308A1 (en) 2003-05-08
WO2003000228A3 (en) 2003-12-18
WO2003000228A2 (en) 2003-01-03

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