ATE28875T1 - Reinigung von ceforanid. - Google Patents

Reinigung von ceforanid.

Info

Publication number
ATE28875T1
ATE28875T1 AT83110435T AT83110435T ATE28875T1 AT E28875 T1 ATE28875 T1 AT E28875T1 AT 83110435 T AT83110435 T AT 83110435T AT 83110435 T AT83110435 T AT 83110435T AT E28875 T1 ATE28875 T1 AT E28875T1
Authority
AT
Austria
Prior art keywords
ceforanide
purification
salt
cephalosporin
purified
Prior art date
Application number
AT83110435T
Other languages
English (en)
Inventor
Paul David Sleezer
Richard Root Smith
Original Assignee
Bristol Myers Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Co filed Critical Bristol Myers Co
Application granted granted Critical
Publication of ATE28875T1 publication Critical patent/ATE28875T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/36—Methylene radicals, substituted by sulfur atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT83110435T 1982-10-20 1983-10-19 Reinigung von ceforanid. ATE28875T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/435,583 US4448958A (en) 1982-10-20 1982-10-20 Purification of ceforanide
EP83110435A EP0106369B1 (de) 1982-10-20 1983-10-19 Reinigung von Ceforanid

Publications (1)

Publication Number Publication Date
ATE28875T1 true ATE28875T1 (de) 1987-08-15

Family

ID=23728969

Family Applications (1)

Application Number Title Priority Date Filing Date
AT83110435T ATE28875T1 (de) 1982-10-20 1983-10-19 Reinigung von ceforanid.

Country Status (5)

Country Link
US (1) US4448958A (de)
EP (1) EP0106369B1 (de)
JP (2) JPH0613524B2 (de)
AT (1) ATE28875T1 (de)
DE (1) DE3372969D1 (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102898442A (zh) * 2012-10-25 2013-01-30 河南中帅医药科技发展有限公司 头孢雷特的精制方法
CN113956270A (zh) * 2021-10-28 2022-01-21 成都大学 一种头孢雷特主要降解产物的制备方法

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3488730A (en) * 1966-09-08 1970-01-06 Lilly Co Eli Salts of cephalosporin antibiotics
GB1265315A (de) * 1968-04-05 1972-03-01 Glaxo Lab Ltd
US3634416A (en) * 1969-03-21 1972-01-11 Glaxo Lab Ltd Purification of 7alpha-aminoarylacetamido delta**3-4-carboxy-cephalosporins
US3766175A (en) * 1971-05-11 1973-10-16 R & L Molecular Research Ltd Certain 7 - (o-aminomethylphenylacetamido) - 3-((heterocyclylthio)methyl)ceph-3-em-4-carboxylic acids
JPS5246237B2 (de) * 1971-12-04 1977-11-22
JPS5422998B2 (de) * 1972-04-21 1979-08-10
US3984403A (en) * 1972-06-30 1976-10-05 Takeda Chemical Industries, Ltd. Arginine and lysine salts of acid cephalosporins
US3830809A (en) * 1972-08-25 1974-08-20 Bristol Myers Co Bis-dicyclohexylamine n-carbisobutoxycephalosporin c
US3907786A (en) * 1973-09-04 1975-09-23 Bristol Myers Co 7-{8 {60 -(2-aminomethyl-1,4-cyclohexadienyl)acetamido{9 -3-heterocyclic-thiomethyl-3-cephem-4-carboxylic acids and salts
US3946000A (en) * 1973-10-31 1976-03-23 Bristol-Myers Company 7-[α-(2-Aminomethyl-1-cyclohexenyl)-acetamido]-3-heterocyclic thiomethyl-3-cephem-4-carboxylic acids
JPS5653557B2 (de) * 1973-10-15 1981-12-19
US4297489A (en) * 1974-09-03 1981-10-27 Bristol-Myers Company 7-α-Amino-substituted acylamino-3-(1-carboxymethyltetrazol-5-ylthiomethyl)-3-cephem-4-carboxylic acids
GB1546757A (en) * 1975-04-10 1979-05-31 Lilly Industries Ltd Crystalline cephalosporin salts
JPS525787A (en) * 1975-06-27 1977-01-17 Bristol Myers Co Antiibacterial agent
US4327279A (en) * 1979-11-27 1982-04-27 Sunsetl, Ltd. Counter-top reheating unit for packaged pre-cooked meals

Also Published As

Publication number Publication date
US4448958A (en) 1984-05-15
JPH085898B2 (ja) 1996-01-24
JPH0665254A (ja) 1994-03-08
EP0106369A2 (de) 1984-04-25
EP0106369B1 (de) 1987-08-12
JPH0613524B2 (ja) 1994-02-23
DE3372969D1 (en) 1987-09-17
JPS5989687A (ja) 1984-05-23
EP0106369A3 (en) 1985-01-30

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Legal Events

Date Code Title Description
EELA Cancelled due to lapse of time