ATE288587T1 - Verfahren zur bestimmung der lipid-aufnahme - Google Patents
Verfahren zur bestimmung der lipid-aufnahmeInfo
- Publication number
- ATE288587T1 ATE288587T1 AT01938489T AT01938489T ATE288587T1 AT E288587 T1 ATE288587 T1 AT E288587T1 AT 01938489 T AT01938489 T AT 01938489T AT 01938489 T AT01938489 T AT 01938489T AT E288587 T1 ATE288587 T1 AT E288587T1
- Authority
- AT
- Austria
- Prior art keywords
- lipid uptake
- determining lipid
- determining
- uptake
- elegans
- Prior art date
Links
- 150000002632 lipids Chemical class 0.000 title abstract 2
- 241000244206 Nematoda Species 0.000 abstract 1
- 239000012190 activator Substances 0.000 abstract 1
- 238000001514 detection method Methods 0.000 abstract 1
- 238000005462 in vivo assay Methods 0.000 abstract 1
- 239000003112 inhibitor Substances 0.000 abstract 1
- 230000000968 intestinal effect Effects 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/5082—Supracellular entities, e.g. tissue, organisms
- G01N33/5085—Supracellular entities, e.g. tissue, organisms of invertebrates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic Table
- C07F5/02—Boron compounds
- C07F5/022—Boron compounds without C-boron linkages
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/92—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving lipids, e.g. cholesterol, lipoproteins, or their receptors
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/43504—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from invertebrates
- G01N2333/43526—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from invertebrates from worms
- G01N2333/4353—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from invertebrates from worms from nematodes
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/43504—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from invertebrates
- G01N2333/43526—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from invertebrates from worms
- G01N2333/4353—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from invertebrates from worms from nematodes
- G01N2333/43534—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from invertebrates from worms from nematodes from Caenorhabditis
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/04—Endocrine or metabolic disorders
- G01N2800/044—Hyperlipemia or hypolipemia, e.g. dyslipidaemia, obesity
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Urology & Nephrology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Cell Biology (AREA)
- Diabetes (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Food Science & Technology (AREA)
- Biochemistry (AREA)
- Pathology (AREA)
- General Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Physics & Mathematics (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Obesity (AREA)
- Endocrinology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Toxicology (AREA)
- Biophysics (AREA)
- Emergency Medicine (AREA)
- Child & Adolescent Psychology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0012229.1A GB0012229D0 (en) | 2000-05-19 | 2000-05-19 | Lipid uptake assays |
| PCT/IB2001/001061 WO2001088533A2 (en) | 2000-05-19 | 2001-05-21 | Lipid uptake assays |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE288587T1 true ATE288587T1 (de) | 2005-02-15 |
Family
ID=9891997
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT01938489T ATE288587T1 (de) | 2000-05-19 | 2001-05-21 | Verfahren zur bestimmung der lipid-aufnahme |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US6703214B2 (de) |
| EP (2) | EP1282816A2 (de) |
| JP (2) | JP2004524803A (de) |
| AT (1) | ATE288587T1 (de) |
| AU (2) | AU2001262601A1 (de) |
| DE (1) | DE60108746T2 (de) |
| GB (2) | GB0012229D0 (de) |
| WO (2) | WO2001088532A2 (de) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2002031202A2 (en) * | 2000-10-10 | 2002-04-18 | Thomas Jefferson University | High throughput genetic screening of lipid and cholesterol processing using fluorescent compounds |
| AU2003239706A1 (en) * | 2002-05-23 | 2003-12-12 | Devgen Nv | Method for determining the influence of a compound on cholesterol transport |
| WO2004033654A2 (en) * | 2002-10-09 | 2004-04-22 | Buck Institute | Automated method for high throughput screening of nematodes |
| CA2592350A1 (en) * | 2004-12-15 | 2006-06-22 | Schering Corporation | Functional assays for cholesterol absorption inhibitors |
| EP2160607B1 (de) * | 2007-05-31 | 2011-09-07 | Sanofi | Testverfahren zur erkennung von wirkstoffen zur modifizierung der aktivität von nape-pld oder abh4 |
| JP5120889B2 (ja) * | 2008-06-12 | 2013-01-16 | 独立行政法人産業技術総合研究所 | ボロンジピロロメタン誘導体及びそれを用いた過酸化脂質測定試薬 |
| CN102288749B (zh) * | 2011-07-28 | 2013-07-31 | 山东农业大学 | 敌百虫仿生酶联免疫吸附检测方法 |
| GB201301043D0 (en) * | 2013-01-21 | 2013-03-06 | Chronos Therapeutics Ltd | Method for assessing cell aging |
| EP2775302A1 (de) * | 2013-03-08 | 2014-09-10 | Assistance Publique - Hôpitaux de Paris | Verbindungsträgersysteme für Tests in Nematoden |
| CN108794518B (zh) * | 2018-04-04 | 2020-06-19 | 安徽师范大学 | 一种以bodipy为基本骨架的有机共轭分子材料及其制备方法 |
| CN109799295A (zh) * | 2019-01-28 | 2019-05-24 | 江南大学 | 一种用于秀丽隐杆线虫代谢组学分析的样品前处理方法 |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4774339A (en) | 1987-08-10 | 1988-09-27 | Molecular Probes, Inc. | Chemically reactive dipyrrometheneboron difluoride dyes |
| AU5106790A (en) * | 1989-02-03 | 1990-09-05 | Cambridge Neuroscience Research, Inc. | Method of screening and classifying compounds |
| US5274113A (en) | 1991-11-01 | 1993-12-28 | Molecular Probes, Inc. | Long wavelength chemically reactive dipyrrometheneboron difluoride dyes and conjugates |
| US5338854A (en) | 1991-02-13 | 1994-08-16 | Molecular Probes, Inc. | Fluorescent fatty acids derived from dipyrrometheneboron difluoride dyes |
| US5583008A (en) * | 1993-05-19 | 1996-12-10 | Nemapharm, Inc. | Rapid diagnostic procedure for ivermectin resistance |
| US6342379B1 (en) * | 1995-06-07 | 2002-01-29 | The Regents Of The University Of California | Detection of transmembrane potentials by optical methods |
| US5994063A (en) * | 1995-06-23 | 1999-11-30 | Metzker; Michael L. | Substituted 4,4-difluoro-4-bora-3A,4A-diaza-s-indacene compounds for homogenous amplification/detection assays |
| US5929062A (en) * | 1997-06-19 | 1999-07-27 | University Of Western Ontario | Oxysterol inhibition of dietary cholesterol uptake |
| US6114177A (en) * | 1997-11-12 | 2000-09-05 | Phytochem Technologies, Inc. | Fluorometric assay for measurement of antioxidant activity |
| CA2314422A1 (en) * | 1997-12-18 | 1999-06-24 | Sepracor Inc. | Methods for the simultaneous identification of novel biological targets and lead structures for drug development |
| US6348321B1 (en) * | 1998-01-15 | 2002-02-19 | Whitehead Institute For Biomedical Research | Methods of identifying agents inhibiting fatty acid transport proteins |
| GB9827152D0 (en) | 1998-07-03 | 1999-02-03 | Devgen Nv | Characterisation of gene function using double stranded rna inhibition |
| GB2351151B (en) | 1999-04-15 | 2001-07-25 | Devgen Nv | Compound Screening Method in Nematode Worms |
| GB9908677D0 (en) | 1999-04-15 | 1999-06-09 | Devgen Nv | Compound assay |
| US6323186B1 (en) * | 1999-09-17 | 2001-11-27 | Molecular Probes, Inc. | Phosphate-bound polyazaindacene derivatives of nucleotides |
-
2000
- 2000-05-19 GB GBGB0012229.1A patent/GB0012229D0/en not_active Ceased
-
2001
- 2001-05-21 AU AU2001262601A patent/AU2001262601A1/en not_active Abandoned
- 2001-05-21 US US09/861,881 patent/US6703214B2/en not_active Expired - Fee Related
- 2001-05-21 JP JP2001584878A patent/JP2004524803A/ja active Pending
- 2001-05-21 GB GB0112360A patent/GB2366615B/en not_active Revoked
- 2001-05-21 DE DE60108746T patent/DE60108746T2/de not_active Expired - Fee Related
- 2001-05-21 EP EP01936742A patent/EP1282816A2/de not_active Withdrawn
- 2001-05-21 AT AT01938489T patent/ATE288587T1/de not_active IP Right Cessation
- 2001-05-21 WO PCT/IB2001/001058 patent/WO2001088532A2/en not_active Ceased
- 2001-05-21 AU AU2001264163A patent/AU2001264163A1/en not_active Abandoned
- 2001-05-21 WO PCT/IB2001/001061 patent/WO2001088533A2/en not_active Ceased
- 2001-05-21 EP EP01938489A patent/EP1285269B1/de not_active Expired - Lifetime
- 2001-05-21 JP JP2001584877A patent/JP2003533696A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| US6703214B2 (en) | 2004-03-09 |
| JP2003533696A (ja) | 2003-11-11 |
| DE60108746T2 (de) | 2006-03-30 |
| US20020137205A1 (en) | 2002-09-26 |
| WO2001088533A3 (en) | 2002-05-16 |
| EP1282816A2 (de) | 2003-02-12 |
| WO2001088532A2 (en) | 2001-11-22 |
| WO2001088532A3 (en) | 2002-04-04 |
| EP1285269A2 (de) | 2003-02-26 |
| GB2366615A (en) | 2002-03-13 |
| WO2001088533A2 (en) | 2001-11-22 |
| GB2366615B (en) | 2002-07-24 |
| AU2001262601A1 (en) | 2001-11-26 |
| GB0112360D0 (en) | 2001-07-11 |
| GB0012229D0 (en) | 2000-07-12 |
| DE60108746D1 (de) | 2005-03-10 |
| JP2004524803A (ja) | 2004-08-19 |
| EP1285269B1 (de) | 2005-02-02 |
| AU2001264163A1 (en) | 2001-11-26 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |