ATE283278T1 - Peptid derivate - Google Patents

Peptid derivate

Info

Publication number
ATE283278T1
ATE283278T1 AT97924156T AT97924156T ATE283278T1 AT E283278 T1 ATE283278 T1 AT E283278T1 AT 97924156 T AT97924156 T AT 97924156T AT 97924156 T AT97924156 T AT 97924156T AT E283278 T1 ATE283278 T1 AT E283278T1
Authority
AT
Austria
Prior art keywords
peptide derivatives
peptide
derivatives
Prior art date
Application number
AT97924156T
Other languages
English (en)
Inventor
Ronald Cotton
Philip Neil Edwards
Richard William Arthur Luke
Keith Oldham
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9611881.5A external-priority patent/GB9611881D0/en
Priority claimed from GBGB9622890.3A external-priority patent/GB9622890D0/en
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Application granted granted Critical
Publication of ATE283278T1 publication Critical patent/ATE283278T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/02—Linear peptides containing at least one abnormal peptide link
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4713—Autoimmune diseases, e.g. Insulin-dependent diabetes mellitus, multiple sclerosis, rheumathoid arthritis, systemic lupus erythematosus; Autoantigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/82—Proteins from microorganisms
    • Y10S530/825—Bacteria
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/827—Proteins from mammals or birds
    • Y10S530/85—Reproductive organs or embryos
    • Y10S530/851—Placenta; amniotic fluid

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Rheumatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Diabetes (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Rehabilitation Therapy (AREA)
  • Hematology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
AT97924156T 1996-06-07 1997-06-03 Peptid derivate ATE283278T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB9611881.5A GB9611881D0 (en) 1996-06-07 1996-06-07 Peptide derivatives
GBGB9622890.3A GB9622890D0 (en) 1996-11-02 1996-11-02 Peptide compounds
PCT/GB1997/001491 WO1997046578A1 (en) 1996-06-07 1997-06-03 Peptide derivatives

Publications (1)

Publication Number Publication Date
ATE283278T1 true ATE283278T1 (de) 2004-12-15

Family

ID=26309459

Family Applications (1)

Application Number Title Priority Date Filing Date
AT97924156T ATE283278T1 (de) 1996-06-07 1997-06-03 Peptid derivate

Country Status (21)

Country Link
US (2) US6541453B2 (de)
EP (1) EP0914333B1 (de)
JP (1) JP2000512277A (de)
KR (1) KR100451522B1 (de)
CN (1) CN1130372C (de)
AR (1) AR008389A1 (de)
AT (1) ATE283278T1 (de)
AU (1) AU727757B2 (de)
BR (1) BR9709533A (de)
CA (1) CA2252417A1 (de)
DE (1) DE69731747T2 (de)
HR (1) HRP970308B1 (de)
ID (1) ID17440A (de)
IL (1) IL127332A0 (de)
NO (1) NO985680L (de)
NZ (1) NZ332347A (de)
PL (1) PL330348A1 (de)
SK (1) SK166798A3 (de)
TR (1) TR199802537T2 (de)
TW (1) TW474947B (de)
WO (1) WO1997046578A1 (de)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9809021D0 (en) * 1998-04-29 1998-06-24 Zeneca Ltd Chemical process
CA2386398A1 (en) * 1999-10-18 2001-04-26 Akzo Nobel Nv Modified peptides and peptidomimetics for use in immunotherapy
JP2008188285A (ja) * 2007-02-06 2008-08-21 Bridgestone Corp バックパッド及び車両用シート
ES2553968T3 (es) 2008-09-18 2015-12-15 Northwestern University Moduladores del receptor NMDA y sus usos
US8951968B2 (en) 2009-10-05 2015-02-10 Northwestern University Methods of treating depression and other related diseases
KR101692275B1 (ko) 2010-02-11 2017-01-04 노오쓰웨스턴 유니버시티 ２차 구조 안정화된 ｎｍｄａ 수용체 조절제 및 그의 용도
MX2012009388A (es) 2010-02-11 2012-10-01 Univ Northwestern Moduladores del receptor de n-metil-d-aspartato estabilizado de estructura secundaria y sus usos.
KR102280616B1 (ko) 2013-01-29 2021-07-21 앱티닉스 인크. 스피로-락탐 nmda 수용체 조절인자 및 그의 용도
CN105229010A (zh) 2013-01-29 2016-01-06 阿普廷伊克斯股份有限公司 螺-内酰胺nmda受体调节剂及其用途
MX2015009772A (es) 2013-01-29 2016-05-31 Aptinyx Inc Moduladores de receptores nmda de espiro-lactama y sus usos.
US9708335B2 (en) 2013-01-29 2017-07-18 Apytinyx Inc. Spiro-lactam NMDA receptor modulators and uses thereof
CN105026401A (zh) 2013-01-29 2015-11-04 诺雷克斯股份有限公司 螺-内酰胺nmda受体调节剂及其用途
WO2017201285A1 (en) 2016-05-19 2017-11-23 Aptinyx Inc. Spiro-lactam nmda receptor modulators and uses thereof
CA3024606C (en) 2016-05-19 2019-09-03 Aptinyx Inc. Spiro-lactam nmda receptor modulators and uses thereof
SG11201900558RA (en) 2016-08-01 2019-02-27 Aptinyx Inc Spiro-lactam nmda receptor modulators and uses thereof
AU2017305240B2 (en) 2016-08-01 2021-12-09 Aptinyx Inc. Spiro-lactam NMDA receptor modulators and uses thereof
SG10202101055VA (en) 2016-08-01 2021-03-30 Aptinyx Inc Spiro-lactam nmda receptor modulators and uses thereof
CN109661398B (zh) 2016-08-01 2022-07-05 阿普廷伊克斯股份有限公司 螺-内酰胺和二-螺-内酰胺nmda受体调节剂及其用途
WO2018026798A1 (en) 2016-08-01 2018-02-08 Aptinyx Inc. Spiro-lactam nmda modulators and methods of using same
MX2020008107A (es) 2018-01-31 2020-09-25 Aptinyx Inc Moduladores del receptor nmda espiro-lactama y usos de los mismos.
CN109115899A (zh) * 2018-06-19 2019-01-01 南京肽业生物科技有限公司 一种Fmoc氨基酸的分析方法
US12012413B2 (en) 2019-11-11 2024-06-18 Tenacia Biotechnology (Hong Kong) Co., Limited Methods of treating painful diabetic peripheral neuropathy
WO2021215952A1 (ru) 2020-04-24 2021-10-28 Общество С Ограниченной Ответственностью "Индженик" Способ получения частиц бактериофагов семейства levivirus

Family Cites Families (23)

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Publication number Priority date Publication date Assignee Title
US4301151A (en) 1979-11-27 1981-11-17 Merck & Co., Inc. Long-lasting agonists of enkephalin
US4254107A (en) 1979-11-27 1981-03-03 Merck & Co., Inc. Long-lasting agonists of enkephalin
US4474778A (en) 1983-11-09 1984-10-02 E. R. Squibb & Sons, Inc. Lactam containing compounds, their pharmaceutical compositions and method of use
US4680283A (en) 1984-09-26 1987-07-14 Merck & Co., Inc. Analogs of substance P and eledoisin
DE3711335A1 (de) 1987-04-03 1988-10-20 Merck Patent Gmbh Aminosaeurederivate
US5331089A (en) 1988-03-25 1994-07-19 Merck Sharpe & Dohme, Ltd. Peptides useful as tachykinin agonists
EP0360390A1 (de) 1988-07-25 1990-03-28 Glaxo Group Limited Spirolactamderivate
WO1990003399A1 (en) * 1988-09-30 1990-04-05 Australian Commercial Research & Development Limited Amino acid transport proteins, amino acid analogues, assay apparatus, uses thereof for treatment and diagnosis of cancer
US5223485A (en) 1989-01-31 1993-06-29 Abbott Laboratories Anaphylatoxin-receptor ligands
AU8305491A (en) 1990-08-01 1992-03-02 Cytel Corporation Novel immunosuppressant peptides
DE4034829A1 (de) 1990-11-02 1992-05-07 Merck Patent Gmbh Cyclopeptide
WO1993005011A1 (en) 1991-08-29 1993-03-18 Sandoz Ltd. Novel immunosuppressants
JPH0725887A (ja) 1993-06-04 1995-01-27 Sterling Winthrop Inc インターロイキン−１β転換酵素阻害剤
JP3926839B2 (ja) 1993-09-14 2007-06-06 エピミューン，インコーポレイティド 万能ｄｒ−結合性ペプチドを用いる免疫応答の改変
CA2186873A1 (en) * 1994-04-01 1995-10-12 Charles J. Hackett Haptenated peptides and uses thereof
JPH10508034A (ja) 1995-03-24 1998-08-04 モレキュメティックス リミテッド βシート模倣物および生物学的に活性なペプチドまたはタンパク質のインヒビターとしてのその使用
US5817757A (en) 1995-10-30 1998-10-06 Merck & Co., Inc. Inhibitors of peptide binding to MHO class II proteins
AU7604196A (en) 1995-10-30 1997-05-22 Merck & Co., Inc. Novel inhibitors of peptide binding to mhc class ii proteins
US5840835A (en) 1995-10-30 1998-11-24 Merck & Co., Inc. Inhibitors of peptide binding to MHC class II proteins
US5719296A (en) 1995-10-30 1998-02-17 Merck & Co., Inc. Pseudopeptide lactam inhibitors of peptide binding to MHC class II proteins
GB9702377D0 (en) 1996-02-23 1997-03-26 Zeneca Ltd Peptide derivatives
GB9621836D0 (en) 1996-10-19 1996-12-11 Zeneca Ltd Peptide compounds
GB9625865D0 (en) 1996-12-12 1997-01-29 Zeneca Ltd Peptides

Also Published As

Publication number Publication date
TW474947B (en) 2002-02-01
AU727757B2 (en) 2000-12-21
CN1221424A (zh) 1999-06-30
AR008389A1 (es) 2000-01-19
US20030195158A1 (en) 2003-10-16
HRP970308A2 (en) 1998-04-30
CA2252417A1 (en) 1997-12-11
IL127332A0 (en) 1999-09-22
NO985680L (no) 1999-02-04
PL330348A1 (en) 1999-05-10
US20020103335A1 (en) 2002-08-01
AU2972097A (en) 1998-01-05
ID17440A (id) 1997-12-24
EP0914333B1 (de) 2004-11-24
HRP970308B1 (en) 2002-04-30
DE69731747D1 (de) 2004-12-30
KR100451522B1 (ko) 2004-12-08
CN1130372C (zh) 2003-12-10
BR9709533A (pt) 1999-08-10
TR199802537T2 (xx) 1999-03-22
EP0914333A1 (de) 1999-05-12
JP2000512277A (ja) 2000-09-19
DE69731747T2 (de) 2006-02-02
NZ332347A (en) 2000-05-26
WO1997046578A1 (en) 1997-12-11
SK166798A3 (en) 1999-07-12
US6541453B2 (en) 2003-04-01
KR20000016465A (ko) 2000-03-25
NO985680D0 (no) 1998-12-04

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Legal Events

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RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties