ATE277063T1 - 6-o-alkylerythromycinoxim b - Google Patents

6-o-alkylerythromycinoxim b

Info

Publication number
ATE277063T1
ATE277063T1 AT98958055T AT98958055T ATE277063T1 AT E277063 T1 ATE277063 T1 AT E277063T1 AT 98958055 T AT98958055 T AT 98958055T AT 98958055 T AT98958055 T AT 98958055T AT E277063 T1 ATE277063 T1 AT E277063T1
Authority
AT
Austria
Prior art keywords
oxime erythromycin
alkyl
alkylerythromycinoxime
alkyl derivative
erythromycin
Prior art date
Application number
AT98958055T
Other languages
English (en)
Inventor
Stephen H Montgomery
Jih-Hua Liu
Original Assignee
Abbott Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Lab filed Critical Abbott Lab
Application granted granted Critical
Publication of ATE277063T1 publication Critical patent/ATE277063T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H1/00—Processes for the preparation of sugar derivatives

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Communicable Diseases (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Epidemiology (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT98958055T 1997-12-01 1998-11-17 6-o-alkylerythromycinoxim b ATE277063T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/980,918 US5932710A (en) 1997-12-01 1997-12-01 Process for preparing 6-O-alkyl-9-oxime erythromycin B
PCT/US1998/024547 WO1999028332A1 (en) 1997-12-01 1998-11-17 6-o-alkyl erythromycin b oxime

Publications (1)

Publication Number Publication Date
ATE277063T1 true ATE277063T1 (de) 2004-10-15

Family

ID=25527956

Family Applications (1)

Application Number Title Priority Date Filing Date
AT98958055T ATE277063T1 (de) 1997-12-01 1998-11-17 6-o-alkylerythromycinoxim b

Country Status (13)

Country Link
US (2) US5932710A (de)
EP (1) EP1042340B1 (de)
JP (1) JP2001525331A (de)
KR (1) KR20010032688A (de)
AT (1) ATE277063T1 (de)
AU (1) AU1417399A (de)
CA (1) CA2309963C (de)
DE (1) DE69826520T2 (de)
DK (1) DK1042340T3 (de)
ES (1) ES2229550T3 (de)
IL (1) IL136088A0 (de)
PT (1) PT1042340E (de)
WO (1) WO1999028332A1 (de)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2244491T3 (es) 1999-12-16 2005-12-16 Teva Pharmaceutical Industries Ltd. Procedimiento para la preparacion de polimorfos de claritromicina y nuevo polimorfo iv.
BR0016992A (pt) 2000-01-11 2002-12-31 Teva Pharma Processos para o preparo de polimorfos de claritromicina
US6544555B2 (en) 2000-02-24 2003-04-08 Advancis Pharmaceutical Corp. Antibiotic product, use and formulation thereof
SK13722002A3 (sk) * 2000-02-29 2003-08-05 Teva Pharmaceutical Industries Ltd. Spôsob prípravy klaritromycínu a klaritromycínového medziproduktu, v podstate prostého oxímu a farmaceutický prostriedok, ktorý ho obsahuje
US20020068078A1 (en) 2000-10-13 2002-06-06 Rudnic Edward M. Antifungal product, use and formulation thereof
US6455680B1 (en) 2000-12-21 2002-09-24 Abbott Laboratories Methods utilizing aryl thioimines in synthesis of erythromycin derivatives
TWI246515B (en) 2001-05-30 2006-01-01 Abbott Lab An arylation method for the functionalization of O-allyl erythromycin derivatives
CA2533178C (en) 2003-07-21 2014-03-11 Advancis Pharmaceutical Corporation Antibiotic product, use and formulation thereof
WO2005009364A2 (en) 2003-07-21 2005-02-03 Advancis Pharmaceutical Corporation Antibiotic product, use and formulation thereof
AU2004258953B2 (en) 2003-07-21 2011-02-10 Shionogi, Inc. Antibiotic product, use and formulation thereof
WO2005016311A1 (en) 2003-08-11 2005-02-24 Advancis Pharmaceutical Corporation Robust pellet
JP2007502294A (ja) 2003-08-12 2007-02-08 アドバンシス ファーマスーティカル コーポレイション 抗生物質製剤、その使用法及び作成方法
AU2004270170B2 (en) * 2003-08-29 2011-01-27 Shionogi, Inc. Antibiotic product, use and formulation thereof
AU2004273830B2 (en) 2003-09-15 2011-03-24 Shionogi, Inc. Antibiotic product, use and formulation thereof
JP2008505124A (ja) 2004-07-02 2008-02-21 アドバンシス ファーマスーティカル コーポレイション パルス送達用錠剤
US8778924B2 (en) 2006-12-04 2014-07-15 Shionogi Inc. Modified release amoxicillin products
US8357394B2 (en) 2005-12-08 2013-01-22 Shionogi Inc. Compositions and methods for improved efficacy of penicillin-type antibiotics
JPWO2007119717A1 (ja) * 2006-04-13 2009-08-27 大正製薬株式会社 アルドヘキソピラノース中間体の製造法
JP5126685B2 (ja) * 2006-05-01 2013-01-23 大正製薬株式会社 マクロライド誘導体
US8299052B2 (en) 2006-05-05 2012-10-30 Shionogi Inc. Pharmaceutical compositions and methods for improved bacterial eradication
JPWO2009019868A1 (ja) 2007-08-06 2010-10-28 大正製薬株式会社 １０ａ、１２位架橋型１０ａ−アザライド化合物
WO2009023191A2 (en) * 2007-08-09 2009-02-19 Teva Pharmaceutical Industries Ltd. An improved process for the preparation of clarithromycin
US8299035B2 (en) 2008-05-15 2012-10-30 Taisho Pharmaceutucal Co., Ltd. 10a-azalide compound having 4-membered ring structure
CN102082088B (zh) * 2009-11-30 2012-04-18 上海华虹Nec电子有限公司 在直接化学机械抛光工艺的产品中共用sl掩模板的方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3681326A (en) * 1971-01-11 1972-08-01 Abbott Lab 9-substituted erythromycin a and b oximes
US3855203A (en) * 1973-05-03 1974-12-17 Abbott Lab 4{41 -o-sulfonyl erythromycin-9-o-oxime derivatives
JPS5896097A (ja) * 1981-12-01 1983-06-07 Taisho Pharmaceut Co Ltd エリスロマイシンｂ誘導体
JPS60214796A (ja) * 1984-04-06 1985-10-28 Taisho Pharmaceut Co Ltd ６−０−メチルエリスロマイシン類の製法
JPS61103890A (ja) * 1984-10-26 1986-05-22 Taisho Pharmaceut Co Ltd ６−０−メチルエリスロマイシンａ誘導体
US4670549A (en) * 1985-03-18 1987-06-02 Taisho Pharmaceutical Co., Ltd. Method for selective methylation of erythromycin a derivatives
US5141926A (en) * 1990-04-18 1992-08-25 Abbott Laboratories Erythromycin derivatives
JP2662094B2 (ja) * 1992-01-21 1997-10-08 アボツト・ラボラトリーズ ４″−デオキシエリスロマイシン誘導体

Also Published As

Publication number Publication date
US6194387B1 (en) 2001-02-27
CA2309963A1 (en) 1999-06-10
WO1999028332A1 (en) 1999-06-10
AU1417399A (en) 1999-06-16
KR20010032688A (ko) 2001-04-25
IL136088A0 (en) 2001-05-20
DE69826520T2 (de) 2005-12-01
ES2229550T3 (es) 2005-04-16
CA2309963C (en) 2008-06-17
JP2001525331A (ja) 2001-12-11
EP1042340B1 (de) 2004-09-22
US5932710A (en) 1999-08-03
DE69826520D1 (en) 2004-10-28
PT1042340E (pt) 2004-12-31
DK1042340T3 (da) 2004-11-29
EP1042340A1 (de) 2000-10-11

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