PT1042340E - Oxima de 6-o-alquil-eritromicina b - Google Patents

Oxima de 6-o-alquil-eritromicina b

Info

Publication number
PT1042340E
PT1042340E PT98958055T PT98958055T PT1042340E PT 1042340 E PT1042340 E PT 1042340E PT 98958055 T PT98958055 T PT 98958055T PT 98958055 T PT98958055 T PT 98958055T PT 1042340 E PT1042340 E PT 1042340E
Authority
PT
Portugal
Prior art keywords
alkyl
eritromycin
oxyme
oxime erythromycin
alkyl derivative
Prior art date
Application number
PT98958055T
Other languages
English (en)
Inventor
Jih-Hua Liu
Stephen H Montgomery
Original Assignee
Abbott Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Lab filed Critical Abbott Lab
Publication of PT1042340E publication Critical patent/PT1042340E/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H1/00—Processes for the preparation of sugar derivatives

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Communicable Diseases (AREA)
  • Epidemiology (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
PT98958055T 1997-12-01 1998-11-17 Oxima de 6-o-alquil-eritromicina b PT1042340E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/980,918 US5932710A (en) 1997-12-01 1997-12-01 Process for preparing 6-O-alkyl-9-oxime erythromycin B

Publications (1)

Publication Number Publication Date
PT1042340E true PT1042340E (pt) 2004-12-31

Family

ID=25527956

Family Applications (1)

Application Number Title Priority Date Filing Date
PT98958055T PT1042340E (pt) 1997-12-01 1998-11-17 Oxima de 6-o-alquil-eritromicina b

Country Status (13)

Country Link
US (2) US5932710A (pt)
EP (1) EP1042340B1 (pt)
JP (1) JP2001525331A (pt)
KR (1) KR20010032688A (pt)
AT (1) ATE277063T1 (pt)
AU (1) AU1417399A (pt)
CA (1) CA2309963C (pt)
DE (1) DE69826520T2 (pt)
DK (1) DK1042340T3 (pt)
ES (1) ES2229550T3 (pt)
IL (1) IL136088A0 (pt)
PT (1) PT1042340E (pt)
WO (1) WO1999028332A1 (pt)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2003516999A (ja) * 1999-12-16 2003-05-20 テバ ファーマシューティカル インダストリーズ リミティド クラリスロマイシン多型体の製法及び多型体ｉｖ
KR20020071012A (ko) 2000-01-11 2002-09-11 테바 파마슈티컬 인더스트리즈 리미티드 클래리스로마이신 다형체의 제조 방법
US6544555B2 (en) 2000-02-24 2003-04-08 Advancis Pharmaceutical Corp. Antibiotic product, use and formulation thereof
PL366021A1 (en) 2000-02-29 2005-01-24 Teva Pharmaceutical Industries Ltd. Processes for preparing clarithromycin and clarithromycin intermediate, essentially oxime-free clarithromycin, and pharmaceutical composition comprising the same
US20020068078A1 (en) 2000-10-13 2002-06-06 Rudnic Edward M. Antifungal product, use and formulation thereof
US6455680B1 (en) 2000-12-21 2002-09-24 Abbott Laboratories Methods utilizing aryl thioimines in synthesis of erythromycin derivatives
TWI246515B (en) 2001-05-30 2006-01-01 Abbott Lab An arylation method for the functionalization of O-allyl erythromycin derivatives
US8313776B2 (en) 2003-07-21 2012-11-20 Shionogi Inc. Antibiotic product, use and formulation thereof
US8425936B2 (en) 2003-07-21 2013-04-23 Shionogi Inc. Antibiotic product, use and formulation thereof
AU2004258953B2 (en) 2003-07-21 2011-02-10 Shionogi, Inc. Antibiotic product, use and formulation thereof
JP2007502296A (ja) 2003-08-11 2007-02-08 アドバンシス ファーマスーティカル コーポレイション ロバストペレット
WO2005016278A2 (en) 2003-08-12 2005-02-24 Advancis Pharmaceuticals Corporation Antibiotic product, use and formulation thereof
WO2005023184A2 (en) * 2003-08-29 2005-03-17 Advancis Pharmaceuticals Corporation Antibiotic product, use and formulation thereof
US8460710B2 (en) 2003-09-15 2013-06-11 Shionogi, Inc. Antibiotic product, use and formulation thereof
CA2572292A1 (en) 2004-07-02 2006-02-09 Advancis Pharmaceutical Corporation Tablet for pulsed delivery
US8357394B2 (en) 2005-12-08 2013-01-22 Shionogi Inc. Compositions and methods for improved efficacy of penicillin-type antibiotics
US8778924B2 (en) 2006-12-04 2014-07-15 Shionogi Inc. Modified release amoxicillin products
JPWO2007119717A1 (ja) * 2006-04-13 2009-08-27 大正製薬株式会社 アルドヘキソピラノース中間体の製造法
RU2455308C2 (ru) * 2006-05-01 2012-07-10 Тайсо Фармасьютикал Ко., Лтд. Макролидные производные
US8299052B2 (en) 2006-05-05 2012-10-30 Shionogi Inc. Pharmaceutical compositions and methods for improved bacterial eradication
EP2177526A4 (en) 2007-08-06 2012-08-22 Taisho Pharmaceutical Co Ltd 10A-AZALIDE COMPOUND CROSS-LINKED IN POSITION 10A AND POSITION 12
WO2009023191A2 (en) * 2007-08-09 2009-02-19 Teva Pharmaceutical Industries Ltd. An improved process for the preparation of clarithromycin
WO2009139181A1 (ja) 2008-05-15 2009-11-19 大正製薬株式会社 ４員環構造を有する１０ａ－アザライド化合物
CN102082088B (zh) * 2009-11-30 2012-04-18 上海华虹Nec电子有限公司 在直接化学机械抛光工艺的产品中共用sl掩模板的方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3681326A (en) * 1971-01-11 1972-08-01 Abbott Lab 9-substituted erythromycin a and b oximes
US3855203A (en) * 1973-05-03 1974-12-17 Abbott Lab 4{41 -o-sulfonyl erythromycin-9-o-oxime derivatives
JPS5896097A (ja) * 1981-12-01 1983-06-07 Taisho Pharmaceut Co Ltd エリスロマイシンｂ誘導体
JPS60214796A (ja) * 1984-04-06 1985-10-28 Taisho Pharmaceut Co Ltd ６−０−メチルエリスロマイシン類の製法
JPS61103890A (ja) * 1984-10-26 1986-05-22 Taisho Pharmaceut Co Ltd ６−０−メチルエリスロマイシンａ誘導体
US4670549A (en) * 1985-03-18 1987-06-02 Taisho Pharmaceutical Co., Ltd. Method for selective methylation of erythromycin a derivatives
US5141926A (en) * 1990-04-18 1992-08-25 Abbott Laboratories Erythromycin derivatives
WO1993013780A1 (en) * 1992-01-21 1993-07-22 Abbott Laboratories 4''-deoxyerythromycin derivatives

Also Published As

Publication number Publication date
EP1042340B1 (en) 2004-09-22
EP1042340A1 (en) 2000-10-11
ES2229550T3 (es) 2005-04-16
ATE277063T1 (de) 2004-10-15
DK1042340T3 (da) 2004-11-29
KR20010032688A (ko) 2001-04-25
AU1417399A (en) 1999-06-16
CA2309963A1 (en) 1999-06-10
US5932710A (en) 1999-08-03
CA2309963C (en) 2008-06-17
US6194387B1 (en) 2001-02-27
DE69826520D1 (en) 2004-10-28
DE69826520T2 (de) 2005-12-01
IL136088A0 (en) 2001-05-20
WO1999028332A1 (en) 1999-06-10
JP2001525331A (ja) 2001-12-11

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