ATE277042T1 - Antimikrobielle 4-oxochinolizine mit 2- pyridongerüsten als teilstruktur - Google Patents
Antimikrobielle 4-oxochinolizine mit 2- pyridongerüsten als teilstrukturInfo
- Publication number
- ATE277042T1 ATE277042T1 AT00969876T AT00969876T ATE277042T1 AT E277042 T1 ATE277042 T1 AT E277042T1 AT 00969876 T AT00969876 T AT 00969876T AT 00969876 T AT00969876 T AT 00969876T AT E277042 T1 ATE277042 T1 AT E277042T1
- Authority
- AT
- Austria
- Prior art keywords
- group
- hydrogen atom
- amino
- oxochinolizine
- pyridone
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D455/00—Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine
- C07D455/02—Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine containing not further condensed quinolizine ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/4375—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having nitrogen as a ring heteroatom, e.g. quinolizines, naphthyridines, berberine, vincamine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Oncology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Communicable Diseases (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP29638399 | 1999-10-19 | ||
PCT/JP2000/007256 WO2001029035A1 (fr) | 1999-10-19 | 2000-10-19 | Antimicrobiens 4-oxoquinolizine presentant des squelettes 2-pyridone en tant que structure partielle |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE277042T1 true ATE277042T1 (de) | 2004-10-15 |
Family
ID=17832846
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT00969876T ATE277042T1 (de) | 1999-10-19 | 2000-10-19 | Antimikrobielle 4-oxochinolizine mit 2- pyridongerüsten als teilstruktur |
Country Status (8)
Country | Link |
---|---|
US (1) | US6525066B2 (de) |
EP (1) | EP1227096B1 (de) |
JP (1) | JP4328049B2 (de) |
AT (1) | ATE277042T1 (de) |
AU (1) | AU7948900A (de) |
DE (1) | DE60014143T2 (de) |
ES (1) | ES2225237T3 (de) |
WO (1) | WO2001029035A1 (de) |
Families Citing this family (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2387016C (en) * | 1999-10-08 | 2010-09-28 | William H. Miller | Acrylamide derivatives as fab i inhibitors |
WO2002022614A1 (fr) * | 2000-09-12 | 2002-03-21 | Sankyo Company,Limited | Derives de quinolizine |
WO2003088897A2 (en) * | 2001-04-06 | 2003-10-30 | Affinium Pharmaceuticals, Inc. | Fab i inhibitors |
ATE404558T1 (de) * | 2001-09-28 | 2008-08-15 | Sato Pharma | Antimikrobielle 4-oxochinolizinverbindungen, die als teilstruktur ein 2-pyridonskelett aufweisen |
EP1575951B1 (de) * | 2002-12-06 | 2014-06-25 | Debiopharm International SA | Heterozyclische verbindungen, verfahren zu deren herstellung und ihre verwendung als heilmittel |
WO2004082586A2 (en) | 2003-03-17 | 2004-09-30 | Affinium Pharmaceuticals, Inc. | Phamaceutical compositions comprising inhibitors of fab i and further antibiotics |
WO2005019224A2 (en) * | 2003-06-06 | 2005-03-03 | Cadila Healthcare Limited | Novel antiinfective compounds |
PL1828167T3 (pl) * | 2004-06-04 | 2015-02-27 | Debiopharm Int Sa | Pochodne akryloamidu jako środki antybiotykowe |
WO2007067416A2 (en) * | 2005-12-05 | 2007-06-14 | Affinium Pharmaceuticals, Inc. | Heterocyclylacrylamide compounds as fabi inhibitors and antibacterial agents |
EP2054422B1 (de) | 2006-07-20 | 2017-06-14 | Debiopharm International SA | Acrylamidderivate als fab-i-inhibitoren |
US20080139574A1 (en) | 2006-11-30 | 2008-06-12 | Cadila Healthcare Limited | Novel quinoline derivatives |
EP3255045A1 (de) * | 2007-02-16 | 2017-12-13 | Debiopharm International SA | Salze, prodrugs und polymorphe von fab i-inhibitoren |
WO2011031745A1 (en) | 2009-09-09 | 2011-03-17 | Achaogen, Inc. | Antibacterial fluoroquinolone analogs |
EP3034078A1 (de) | 2010-09-27 | 2016-06-22 | Emergent Product Development Gaithersburg Inc. | Antimikrobielle 2-pyridon-zusammensetzungen |
WO2012104305A1 (en) * | 2011-02-01 | 2012-08-09 | Evolva Sa | Antimicrobial 4-oxoquinolizines |
JP6085026B2 (ja) | 2012-06-19 | 2017-02-22 | デビオファーム インターナショナル エスエーDebiopharm International Sa | (e)−n−メチル−n−((3−メチルベンゾフラン−2−イル)メチル)−3−(7−オキソ−5,6,7,8−テトラヒドロ−1,8−ナフチリジン−3−イル)アクリルアミドのプロドラッグ誘導体 |
US10751351B2 (en) | 2016-02-26 | 2020-08-25 | Debiopharm International S.A. | Medicament for treatment of diabetic foot infections |
CN110938028B (zh) * | 2019-12-09 | 2022-03-04 | 南京杰运医药科技有限公司 | 一种(1r)-5-溴-2,3-二氢-1-甲基-1h-异吲哚的制备方法 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU689809B2 (en) * | 1993-10-14 | 1998-04-09 | Abbott Laboratories | Quinolizinone type compounds |
DK0775702T3 (da) | 1994-08-12 | 2003-08-18 | Toyama Chemical Co Ltd | Hidtil ukendte quinolon- eller naphthylidoncarboxylsyrederivater eller salt deraf |
JP3833738B2 (ja) | 1995-11-15 | 2006-10-18 | 第一製薬株式会社 | 置換アミノメチルピロリジン誘導体 |
WO2002022614A1 (fr) * | 2000-09-12 | 2002-03-21 | Sankyo Company,Limited | Derives de quinolizine |
-
2000
- 2000-10-19 AU AU79489/00A patent/AU7948900A/en not_active Abandoned
- 2000-10-19 AT AT00969876T patent/ATE277042T1/de not_active IP Right Cessation
- 2000-10-19 WO PCT/JP2000/007256 patent/WO2001029035A1/ja active IP Right Grant
- 2000-10-19 JP JP2001531834A patent/JP4328049B2/ja not_active Expired - Fee Related
- 2000-10-19 ES ES00969876T patent/ES2225237T3/es not_active Expired - Lifetime
- 2000-10-19 DE DE60014143T patent/DE60014143T2/de not_active Expired - Fee Related
- 2000-10-19 EP EP00969876A patent/EP1227096B1/de not_active Expired - Lifetime
-
2002
- 2002-04-18 US US10/124,485 patent/US6525066B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
WO2001029035A1 (fr) | 2001-04-26 |
EP1227096B1 (de) | 2004-09-22 |
US20020173517A1 (en) | 2002-11-21 |
AU7948900A (en) | 2001-04-30 |
US6525066B2 (en) | 2003-02-25 |
EP1227096A4 (de) | 2003-04-02 |
DE60014143D1 (de) | 2004-10-28 |
ES2225237T3 (es) | 2005-03-16 |
DE60014143T2 (de) | 2006-03-02 |
JP4328049B2 (ja) | 2009-09-09 |
EP1227096A1 (de) | 2002-07-31 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
ATE277042T1 (de) | Antimikrobielle 4-oxochinolizine mit 2- pyridongerüsten als teilstruktur | |
AP2002002603A0 (en) | 3-aminoquinazolin-2,4-dione antibacterial agents. | |
BR9913097B1 (pt) | Derivado heterocíclico de carboxamida contendo nitrogênio ou um sal do mesmo | |
PE20011348A1 (es) | Agentes antivirales de imidazopiridina e imidazopimiridina | |
RS51444B (sr) | JEDINJENJA KOJA SADRŽE LAKTAM I NJIHOVI DERIVATI KAO INHIBITORI FAKTORA Xa | |
ATE392411T1 (de) | Neue substituierte anilinderivate mit herbizider wirkung | |
MY132698A (en) | Herbicidal composition | |
HUP9802822A2 (hu) | Halogén-benzimidazol-származékok, intermedierjeik, előállításuk és a vegyületeket hatóanyagként tartalmazó mikrobicid készítmények | |
ATE161257T1 (de) | Azolylamin-derivat | |
PT976748E (pt) | Derivados de pirrolidina com actividade inibidora de fosfolipase a2 | |
DK1180519T3 (da) | Hydrochlorid af en kondenseret heterocyklisk forbindelse | |
PH12015501098A1 (en) | Antituberculous composition comprising oxazole compounds | |
MY138466A (en) | Aminoalkoxyndoles as 5-ht6-receptor ligands for the treatment of cns-disorders | |
EP1357124A4 (de) | Heterocyclische verbindungen und mittel, die die hirnfunktion verbessern und als wirkstoff diese verbindungen enthalten | |
AU9025601A (en) | Cephem compounds and esbl-detecting reagents containing the same | |
TW200505446A (en) | Inhibitor of cox | |
MXPA05006450A (es) | Nuevo derivado de 2,4-diamino-1,3,5-triazina. | |
DE60227655D1 (de) | Pyrrolderivat | |
DK1433480T3 (da) | Lægemiddel indeholdende pyrimidin-derivat | |
EP1557407A4 (de) | Neue alpha-ketoamidderivate und deren verwendung | |
DK1140919T3 (da) | 1,4-Disubstituerede cyclohexanderivater til behandling af depression | |
EP1489076A4 (de) | Cyclisches hemiacetalderivat und dessen anwendung |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
UEP | Publication of translation of european patent specification |
Ref document number: 1227096 Country of ref document: EP |
|
REN | Ceased due to non-payment of the annual fee |