ATE274376T1 - Magnetische anordnung für zellen-trennung und verfahren zur trennung - Google Patents

Magnetische anordnung für zellen-trennung und verfahren zur trennung

Info

Publication number
ATE274376T1
ATE274376T1 AT98928931T AT98928931T ATE274376T1 AT E274376 T1 ATE274376 T1 AT E274376T1 AT 98928931 T AT98928931 T AT 98928931T AT 98928931 T AT98928931 T AT 98928931T AT E274376 T1 ATE274376 T1 AT E274376T1
Authority
AT
Austria
Prior art keywords
magnets
solution
separation
magnetized
vessel
Prior art date
Application number
AT98928931T
Other languages
German (de)
English (en)
Inventor
Martin D Sterman
Paul Lituri
Richard E Stelter
Original Assignee
Genzyme Corp
Permag Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genzyme Corp, Permag Corp filed Critical Genzyme Corp
Application granted granted Critical
Publication of ATE274376T1 publication Critical patent/ATE274376T1/de

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B03—SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C—MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C1/00—Magnetic separation
    • B03C1/02—Magnetic separation acting directly on the substance being separated
    • B03C1/035—Open gradient magnetic separators, i.e. separators in which the gap is unobstructed, characterised by the configuration of the gap
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B03—SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C—MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C1/00—Magnetic separation
    • B03C1/02—Magnetic separation acting directly on the substance being separated
    • B03C1/025—High gradient magnetic separators
    • B03C1/031—Component parts; Auxiliary operations
    • B03C1/033—Component parts; Auxiliary operations characterised by the magnetic circuit
    • B03C1/0332—Component parts; Auxiliary operations characterised by the magnetic circuit using permanent magnets
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B03—SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C—MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C1/00—Magnetic separation
    • B03C1/02—Magnetic separation acting directly on the substance being separated
    • B03C1/28—Magnetic plugs and dipsticks
    • B03C1/288—Magnetic plugs and dipsticks disposed at the outer circumference of a recipient
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01F—MAGNETS; INDUCTANCES; TRANSFORMERS; SELECTION OF MATERIALS FOR THEIR MAGNETIC PROPERTIES
    • H01F7/00—Magnets
    • H01F7/02—Permanent magnets [PM]
    • H01F7/0273—Magnetic circuits with PM for magnetic field generation
    • H01F7/0278—Magnetic circuits with PM for magnetic field generation for generating uniform fields, focusing, deflecting electrically charged particles
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B03—SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C—MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C2201/00—Details of magnetic or electrostatic separation
    • B03C2201/18—Magnetic separation whereby the particles are suspended in a liquid
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B03—SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C—MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C2201/00—Details of magnetic or electrostatic separation
    • B03C2201/22—Details of magnetic or electrostatic separation characterised by the magnetic field, e.g. its shape or generation
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B03—SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C—MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C2201/00—Details of magnetic or electrostatic separation
    • B03C2201/26—Details of magnetic or electrostatic separation for use in medical or biological applications

Landscapes

  • Physics & Mathematics (AREA)
  • Electromagnetism (AREA)
  • Engineering & Computer Science (AREA)
  • Power Engineering (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Centrifugal Separators (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Investigating Or Analyzing Materials By The Use Of Magnetic Means (AREA)
AT98928931T 1997-06-04 1998-06-04 Magnetische anordnung für zellen-trennung und verfahren zur trennung ATE274376T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/868,598 US6451207B1 (en) 1997-06-04 1997-06-04 Magnetic cell separation device
PCT/US1998/011816 WO1998055236A1 (en) 1997-06-04 1998-06-04 Magnetic cell separation device

Publications (1)

Publication Number Publication Date
ATE274376T1 true ATE274376T1 (de) 2004-09-15

Family

ID=25351973

Family Applications (1)

Application Number Title Priority Date Filing Date
AT98928931T ATE274376T1 (de) 1997-06-04 1998-06-04 Magnetische anordnung für zellen-trennung und verfahren zur trennung

Country Status (8)

Country Link
US (2) US6451207B1 (enExample)
EP (1) EP0986436B1 (enExample)
JP (1) JP4444377B2 (enExample)
AT (1) ATE274376T1 (enExample)
AU (1) AU753848B2 (enExample)
CA (1) CA2292631C (enExample)
DE (1) DE69825890T2 (enExample)
WO (1) WO1998055236A1 (enExample)

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US9597395B2 (en) 2001-12-07 2017-03-21 Cytori Therapeutics, Inc. Methods of using adipose tissue-derived cells in the treatment of cardiovascular conditions
US20050095228A1 (en) 2001-12-07 2005-05-05 Fraser John K. Methods of using regenerative cells in the treatment of peripheral vascular disease and related disorders
US8105580B2 (en) 2001-12-07 2012-01-31 Cytori Therapeutics, Inc. Methods of using adipose derived stem cells to promote wound healing
US7771716B2 (en) 2001-12-07 2010-08-10 Cytori Therapeutics, Inc. Methods of using regenerative cells in the treatment of musculoskeletal disorders
US20030161816A1 (en) 2001-12-07 2003-08-28 Fraser John K. Systems and methods for treating patients with processed lipoaspirate cells
US7585670B2 (en) 2001-12-07 2009-09-08 Cytori Therapeutics, Inc. Automated methods for isolating and using clinically safe adipose derived regenerative cells
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US7162302B2 (en) 2002-03-04 2007-01-09 Nanoset Llc Magnetically shielded assembly
US20040225213A1 (en) 2002-01-22 2004-11-11 Xingwu Wang Magnetic resonance imaging coated assembly
US7091412B2 (en) 2002-03-04 2006-08-15 Nanoset, Llc Magnetically shielded assembly
US6846985B2 (en) 2002-01-22 2005-01-25 Nanoset, Llc Magnetically shielded assembly
US7011758B2 (en) * 2002-02-11 2006-03-14 The Board Of Trustees Of The University Of Illinois Methods and systems for membrane testing
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US7102005B2 (en) * 2002-05-03 2006-09-05 Molecular Probes, Inc. Compositions and methods for detection and isolation of phosphorylated molecules
US20040140875A1 (en) * 2003-01-22 2004-07-22 Strom Carl H. Unipolar magnetic system
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US8211386B2 (en) 2004-06-08 2012-07-03 Biokit, S.A. Tapered cuvette and method of collecting magnetic particles
US20060051265A1 (en) * 2004-09-08 2006-03-09 Health Research, Inc. Apparatus and method for sorting microstructures in a fluid medium
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EP1904237B1 (en) * 2005-06-24 2013-08-14 Sepmag Systems, S.L. Device and method for separating magnetic particles
US20070018764A1 (en) * 2005-07-19 2007-01-25 Analisi Tecnologica Innovadora Per A Processos Device and method for separating magnetic particles
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US7867765B2 (en) 2005-12-28 2011-01-11 The General Hospital Corporation Blood cell sorting methods and systems
WO2007139551A1 (en) * 2006-05-30 2007-12-06 Cytori Therapeutics, Inc. Systems and methods for manipulation of regenerative cells from adipose tissue
WO2008013863A2 (en) * 2006-07-26 2008-01-31 Cytori Therapeutics, Inc. Generation of adipose tissue and adipocytes
WO2008080047A2 (en) * 2006-12-23 2008-07-03 Baxter International Inc. Magnetic separation of fine particles from compositions
DE102007043281A1 (de) 2007-09-11 2009-05-28 Sebastian Dr. med. Chakrit Bhakdi Vorrichtung, Materialien und Verfahren zur Hochgradientenmagnetseparation biologischen Materials
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WO2016002256A1 (ja) * 2014-07-03 2016-01-07 三菱電機株式会社 渦電流選別装置および渦電流選別方法
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CN110004062B (zh) * 2019-04-18 2022-07-01 中国人民解放军第四军医大学 分选富集数量极稀少循环肿瘤细胞的装置和方法
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WO2025145622A1 (zh) * 2024-01-04 2025-07-10 北京麦戈龙生物科技有限公司 磁性粒子分离装置
CN117839863B (zh) * 2024-01-04 2025-02-25 北京麦戈龙科技有限公司 磁性粒子分离装置
CN117884254B (zh) * 2024-01-04 2025-02-25 北京麦戈龙科技有限公司 磁性粒子分离装置

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Also Published As

Publication number Publication date
DE69825890D1 (de) 2004-09-30
US6451207B1 (en) 2002-09-17
JP2002504852A (ja) 2002-02-12
EP0986436B1 (en) 2004-08-25
WO1998055236A1 (en) 1998-12-10
CA2292631C (en) 2008-01-15
CA2292631A1 (en) 1998-12-10
EP0986436A1 (en) 2000-03-22
DE69825890T2 (de) 2005-09-08
AU753848B2 (en) 2002-10-31
JP4444377B2 (ja) 2010-03-31
AU8061698A (en) 1998-12-21
US20030015474A1 (en) 2003-01-23
US6572778B2 (en) 2003-06-03

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