AU753848B2 - Magnetic cell separation device - Google Patents

Magnetic cell separation device Download PDF

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Publication number
AU753848B2
AU753848B2 AU80616/98A AU8061698A AU753848B2 AU 753848 B2 AU753848 B2 AU 753848B2 AU 80616/98 A AU80616/98 A AU 80616/98A AU 8061698 A AU8061698 A AU 8061698A AU 753848 B2 AU753848 B2 AU 753848B2
Authority
AU
Australia
Prior art keywords
adjacent
magnets
magnet
interpolar
magnetic device
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
AU80616/98A
Other languages
English (en)
Other versions
AU8061698A (en
Inventor
Paul Lituri
Richard E. Stelter
Martin D. Sterman
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Genzyme Corp
Permag Corp
Original Assignee
Genzyme Corp
Permag Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genzyme Corp, Permag Corp filed Critical Genzyme Corp
Publication of AU8061698A publication Critical patent/AU8061698A/en
Application granted granted Critical
Publication of AU753848B2 publication Critical patent/AU753848B2/en
Anticipated expiration legal-status Critical
Expired legal-status Critical Current

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Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B03—SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C—MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C1/00—Magnetic separation
    • B03C1/02—Magnetic separation acting directly on the substance being separated
    • B03C1/035—Open gradient magnetic separators, i.e. separators in which the gap is unobstructed, characterised by the configuration of the gap
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B03—SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C—MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C1/00—Magnetic separation
    • B03C1/02—Magnetic separation acting directly on the substance being separated
    • B03C1/025—High gradient magnetic separators
    • B03C1/031—Component parts; Auxiliary operations
    • B03C1/033—Component parts; Auxiliary operations characterised by the magnetic circuit
    • B03C1/0332—Component parts; Auxiliary operations characterised by the magnetic circuit using permanent magnets
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B03—SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C—MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C1/00—Magnetic separation
    • B03C1/02—Magnetic separation acting directly on the substance being separated
    • B03C1/28—Magnetic plugs and dipsticks
    • B03C1/288—Magnetic plugs and dipsticks disposed at the outer circumference of a recipient
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01F—MAGNETS; INDUCTANCES; TRANSFORMERS; SELECTION OF MATERIALS FOR THEIR MAGNETIC PROPERTIES
    • H01F7/00—Magnets
    • H01F7/02—Permanent magnets [PM]
    • H01F7/0273—Magnetic circuits with PM for magnetic field generation
    • H01F7/0278—Magnetic circuits with PM for magnetic field generation for generating uniform fields, focusing, deflecting electrically charged particles
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B03—SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C—MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C2201/00—Details of magnetic or electrostatic separation
    • B03C2201/18—Magnetic separation whereby the particles are suspended in a liquid
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B03—SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C—MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C2201/00—Details of magnetic or electrostatic separation
    • B03C2201/22—Details of magnetic or electrostatic separation characterised by the magnetic field, e.g. its shape or generation
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B03—SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C—MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C2201/00—Details of magnetic or electrostatic separation
    • B03C2201/26—Details of magnetic or electrostatic separation for use in medical or biological applications

Landscapes

  • Physics & Mathematics (AREA)
  • Electromagnetism (AREA)
  • Engineering & Computer Science (AREA)
  • Power Engineering (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Centrifugal Separators (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Investigating Or Analyzing Materials By The Use Of Magnetic Means (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
AU80616/98A 1997-06-04 1998-06-04 Magnetic cell separation device Expired AU753848B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US08/868598 1997-06-04
US08/868,598 US6451207B1 (en) 1997-06-04 1997-06-04 Magnetic cell separation device
PCT/US1998/011816 WO1998055236A1 (en) 1997-06-04 1998-06-04 Magnetic cell separation device

Publications (2)

Publication Number Publication Date
AU8061698A AU8061698A (en) 1998-12-21
AU753848B2 true AU753848B2 (en) 2002-10-31

Family

ID=25351973

Family Applications (1)

Application Number Title Priority Date Filing Date
AU80616/98A Expired AU753848B2 (en) 1997-06-04 1998-06-04 Magnetic cell separation device

Country Status (8)

Country Link
US (2) US6451207B1 (enExample)
EP (1) EP0986436B1 (enExample)
JP (1) JP4444377B2 (enExample)
AT (1) ATE274376T1 (enExample)
AU (1) AU753848B2 (enExample)
CA (1) CA2292631C (enExample)
DE (1) DE69825890T2 (enExample)
WO (1) WO1998055236A1 (enExample)

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DE10136060A1 (de) * 2001-07-25 2003-02-13 Roche Diagnostics Gmbh System zur Separation von magnetisch anziehbaren Partikeln
US7651684B2 (en) 2001-12-07 2010-01-26 Cytori Therapeutics, Inc. Methods of using adipose tissue-derived cells in augmenting autologous fat transfer
US20050095228A1 (en) 2001-12-07 2005-05-05 Fraser John K. Methods of using regenerative cells in the treatment of peripheral vascular disease and related disorders
US7585670B2 (en) 2001-12-07 2009-09-08 Cytori Therapeutics, Inc. Automated methods for isolating and using clinically safe adipose derived regenerative cells
CA2469370C (en) 2001-12-07 2014-07-08 Macropore Biosurgery, Inc. Adipose-derived cell processing unit
US8105580B2 (en) 2001-12-07 2012-01-31 Cytori Therapeutics, Inc. Methods of using adipose derived stem cells to promote wound healing
US9597395B2 (en) 2001-12-07 2017-03-21 Cytori Therapeutics, Inc. Methods of using adipose tissue-derived cells in the treatment of cardiovascular conditions
US7771716B2 (en) 2001-12-07 2010-08-10 Cytori Therapeutics, Inc. Methods of using regenerative cells in the treatment of musculoskeletal disorders
US6846985B2 (en) 2002-01-22 2005-01-25 Nanoset, Llc Magnetically shielded assembly
US7162302B2 (en) 2002-03-04 2007-01-09 Nanoset Llc Magnetically shielded assembly
US20040225213A1 (en) 2002-01-22 2004-11-11 Xingwu Wang Magnetic resonance imaging coated assembly
US7091412B2 (en) 2002-03-04 2006-08-15 Nanoset, Llc Magnetically shielded assembly
US7011758B2 (en) * 2002-02-11 2006-03-14 The Board Of Trustees Of The University Of Illinois Methods and systems for membrane testing
WO2003086637A1 (en) 2002-04-12 2003-10-23 Instrumentation Laboratory Company Immunoassay probe
CN1665790A (zh) * 2002-05-03 2005-09-07 莫莱丘莱尔探针公司 用于检测和分离磷酸化分子的组合物及方法
US20040140875A1 (en) * 2003-01-22 2004-07-22 Strom Carl H. Unipolar magnetic system
ATE524070T1 (de) 2003-02-20 2011-09-15 Cytori Therapeutics Inc Verfahren zur verwendung von aus fettgewebe stammenden zellen bei der behandlung von herz- kreislauf-leiden
WO2005028640A1 (en) * 2003-09-19 2005-03-31 Newsouth Innovations Pty Limited Method for isolating hepatocytes
JP2005128771A (ja) * 2003-10-23 2005-05-19 Fujitsu Ltd データファイルシステム、データアクセスサーバ、およびデータアクセスプログラム
US20050266394A1 (en) * 2003-12-24 2005-12-01 Massachusette Institute Of Technology Magnetophoretic cell clarification
US8211386B2 (en) 2004-06-08 2012-07-03 Biokit, S.A. Tapered cuvette and method of collecting magnetic particles
US20060051265A1 (en) * 2004-09-08 2006-03-09 Health Research, Inc. Apparatus and method for sorting microstructures in a fluid medium
NL1028845C2 (nl) * 2005-04-22 2006-10-24 Rail Road Systems B V Inrichting voor het creeren van een substantieel magneetveld vrij gebied omgeven door een gebied met een magneetveld gradient.
WO2006136237A1 (en) * 2005-06-24 2006-12-28 Analisi Tecnologica Innovadora Per A Processos Industrials Competitius, S.L. Device and method for separating magnetic particles
US20070018764A1 (en) * 2005-07-19 2007-01-25 Analisi Tecnologica Innovadora Per A Processos Device and method for separating magnetic particles
NL1030761C2 (nl) * 2005-12-23 2007-06-29 Bakker Holding Son Bv Werkwijze en inrichting voor het scheiden van vaste deeltjes op basis van dichtheidsverschil.
EP1996931B1 (en) 2005-12-28 2013-11-27 The General Hospital Corporation Blood cell sorting methods and systems
US20090304644A1 (en) * 2006-05-30 2009-12-10 Cytori Therapeutics, Inc. Systems and methods for manipulation of regenerative cells separated and concentrated from adipose tissue
US20100015104A1 (en) * 2006-07-26 2010-01-21 Cytori Therapeutics, Inc Generation of adipose tissue and adipocytes
US20090152176A1 (en) * 2006-12-23 2009-06-18 Baxter International Inc. Magnetic separation of fine particles from compositions
DE102007043281A1 (de) 2007-09-11 2009-05-28 Sebastian Dr. med. Chakrit Bhakdi Vorrichtung, Materialien und Verfahren zur Hochgradientenmagnetseparation biologischen Materials
EP2306959A2 (en) * 2008-07-11 2011-04-13 The General Hospital Corporation Magnetic apparatus for blood separation
WO2010021993A1 (en) 2008-08-19 2010-02-25 Cytori Therapeutics, Inc. Methods of using adipose tissue-derived cells in the treatment of the lymphatic system and malignant disease
US20100099076A1 (en) * 2008-10-16 2010-04-22 Kent State University Sensitive and rapid detection of viral particles in early viral infection by laser tweezers
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EP2553686A4 (en) 2010-03-29 2015-01-21 Glenn Lane Family Ltd Liability Ltd Partnership SPATIAL SEGREGATION OF PLASMA COMPONENTS
CN103501913B (zh) 2011-03-11 2017-02-15 杨贵生 磁性颗粒清除装置及方法
US20120262260A1 (en) * 2011-04-18 2012-10-18 Exact Sciences Corporation Magnetic microparticle localization device
AU2012245294B2 (en) 2011-04-20 2015-10-29 Magglobal, Llc Iron ore separation device
KR20150130557A (ko) 2013-03-15 2015-11-23 글렌 레인 패밀리 리미티드 리에빌러티 리미티드 파트너쉽 조정 가능한 질량 분해 애퍼쳐
MX2016003127A (es) 2013-09-19 2016-10-28 Cytori Therapeutics Inc Metodos de uso de células derivadas de tejido adiposo en la modulación de dolor y/o fibrosis.
CN106457314A (zh) * 2014-07-03 2017-02-22 三菱电机株式会社 涡电流分选装置以及涡电流分选方法
US9387486B2 (en) * 2014-09-30 2016-07-12 Ut-Battelle, Llc High-gradient permanent magnet apparatus and its use in particle collection
EP3609993A1 (en) 2017-04-13 2020-02-19 Universiteit Antwerpen Micro algae harvesting methods and devices
US12145151B2 (en) * 2018-03-03 2024-11-19 Applied Cells Inc. Methods and apparatus to separate biological entities
US11278915B1 (en) 2018-07-20 2022-03-22 NeoGeneStar LLC Device for capturing and releasing magnetic particles
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CN110004062B (zh) * 2019-04-18 2022-07-01 中国人民解放军第四军医大学 分选富集数量极稀少循环肿瘤细胞的装置和方法
DE102021125870A1 (de) * 2021-10-05 2023-04-06 Sekels Gmbh Vorrichtung zur Bewegung eines magnetischen Objekts in einem Behältnis
EP4344786A1 (en) 2022-09-27 2024-04-03 Sepmag Systems, S.L. Biomagnetic separation system with double ring profile
CN117884254B (zh) * 2024-01-04 2025-02-25 北京麦戈龙科技有限公司 磁性粒子分离装置
CN117839863B (zh) * 2024-01-04 2025-02-25 北京麦戈龙科技有限公司 磁性粒子分离装置
WO2025145622A1 (zh) * 2024-01-04 2025-07-10 北京麦戈龙生物科技有限公司 磁性粒子分离装置

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Also Published As

Publication number Publication date
EP0986436A1 (en) 2000-03-22
US20030015474A1 (en) 2003-01-23
CA2292631C (en) 2008-01-15
DE69825890D1 (de) 2004-09-30
JP2002504852A (ja) 2002-02-12
WO1998055236A1 (en) 1998-12-10
DE69825890T2 (de) 2005-09-08
ATE274376T1 (de) 2004-09-15
AU8061698A (en) 1998-12-21
JP4444377B2 (ja) 2010-03-31
EP0986436B1 (en) 2004-08-25
US6572778B2 (en) 2003-06-03
CA2292631A1 (en) 1998-12-10
US6451207B1 (en) 2002-09-17

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Legal Events

Date Code Title Description
FGA Letters patent sealed or granted (standard patent)
MK14 Patent ceased section 143(a) (annual fees not paid) or expired