ATE274344T1 - Pharmazeutische zubereitung mit verzögerter wirkstofffreisetzung von phenytoin natrium - Google Patents
Pharmazeutische zubereitung mit verzögerter wirkstofffreisetzung von phenytoin natriumInfo
- Publication number
- ATE274344T1 ATE274344T1 AT99935347T AT99935347T ATE274344T1 AT E274344 T1 ATE274344 T1 AT E274344T1 AT 99935347 T AT99935347 T AT 99935347T AT 99935347 T AT99935347 T AT 99935347T AT E274344 T1 ATE274344 T1 AT E274344T1
- Authority
- AT
- Austria
- Prior art keywords
- coating
- active ingredient
- sustained release
- phenytoin sodium
- pharmaceutical preparation
- Prior art date
Links
- 229960002790 phenytoin sodium Drugs 0.000 title abstract 2
- FJPYVLNWWICYDW-UHFFFAOYSA-M sodium;5,5-diphenylimidazolidin-1-ide-2,4-dione Chemical compound [Na+].O=C1[N-]C(=O)NC1(C=1C=CC=CC=1)C1=CC=CC=C1 FJPYVLNWWICYDW-UHFFFAOYSA-M 0.000 title abstract 2
- 230000003111 delayed effect Effects 0.000 title 1
- 239000000825 pharmaceutical preparation Substances 0.000 title 1
- 239000004480 active ingredient Substances 0.000 abstract 6
- 239000011248 coating agent Substances 0.000 abstract 3
- 238000000576 coating method Methods 0.000 abstract 3
- 239000002702 enteric coating Substances 0.000 abstract 3
- 238000009505 enteric coating Methods 0.000 abstract 3
- 238000013268 sustained release Methods 0.000 abstract 3
- 239000012730 sustained-release form Substances 0.000 abstract 3
- 238000012377 drug delivery Methods 0.000 abstract 2
- 230000001419 dependent effect Effects 0.000 abstract 1
- 239000002552 dosage form Substances 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 239000011253 protective coating Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
- A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5026—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
- A61K9/5042—Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose
- A61K9/5047—Cellulose ethers containing no ester groups, e.g. hydroxypropyl methylcellulose
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Indole Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09/111,188 US5968554A (en) | 1998-07-07 | 1998-07-07 | Sustained release pharmaceutical preparation |
| US09/338,716 US6312728B1 (en) | 1998-07-07 | 1999-06-23 | Sustained release pharmaceutical preparation |
| PCT/US1999/014204 WO2000001369A1 (en) | 1998-07-07 | 1999-06-25 | Sustained release pharmaceutical preparation |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE274344T1 true ATE274344T1 (de) | 2004-09-15 |
Family
ID=26808709
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT99935347T ATE274344T1 (de) | 1998-07-07 | 1999-06-25 | Pharmazeutische zubereitung mit verzögerter wirkstofffreisetzung von phenytoin natrium |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US6312728B1 (enExample) |
| EP (1) | EP1094790B9 (enExample) |
| JP (1) | JP2003524592A (enExample) |
| AT (1) | ATE274344T1 (enExample) |
| AU (1) | AU5084299A (enExample) |
| CA (1) | CA2337046C (enExample) |
| DE (1) | DE69919713T2 (enExample) |
| ES (1) | ES2226412T3 (enExample) |
| IL (1) | IL140761A0 (enExample) |
| WO (1) | WO2000001369A1 (enExample) |
Families Citing this family (48)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE9803871D0 (sv) * | 1998-11-11 | 1998-11-11 | Pharmacia & Upjohn Ab | Therapeutic method and formulation |
| US20030068356A1 (en) * | 2001-07-10 | 2003-04-10 | Pather S. Indiran | Sequential drug delivery systems |
| US6572889B1 (en) | 2002-03-07 | 2003-06-03 | Noveon Ip Holdings Corp. | Controlled release solid dosage carbamazepine formulations |
| US20040043067A1 (en) * | 2002-06-19 | 2004-03-04 | Salamone Joseph C. | Fluorosiloxane matrix controlled diffusion drug delivery systems |
| US8679533B2 (en) | 2002-07-25 | 2014-03-25 | Pharmacia Corporation | Pramipexole once-daily dosage form |
| WO2004041244A2 (en) * | 2002-10-30 | 2004-05-21 | Pharmacia Corporation | Oral extended release tablets and methods of making and using the same |
| US7988993B2 (en) * | 2002-12-09 | 2011-08-02 | Andrx Pharmaceuticals, Inc. | Oral controlled release dosage form |
| US20040253293A1 (en) * | 2003-06-16 | 2004-12-16 | Afshin Shafiee | Rate controlled release of a pharmaceutical agent in a biodegradable device |
| JP2007507491A (ja) * | 2003-09-29 | 2007-03-29 | シージェー コーポレーション | 徐放性製剤 |
| US7670624B2 (en) * | 2004-01-29 | 2010-03-02 | Astella Pharma Inc. | Gastrointestinal-specific multiple drug release system |
| WO2005117697A2 (en) * | 2004-05-28 | 2005-12-15 | Narayanan Ramasubramanian | Unified indigestion package and process for patient compliance with prescribed medication regimen |
| US20070003622A1 (en) * | 2004-12-16 | 2007-01-04 | Sovereign Pharmaceuticals, Ltd. | Diphenhydramine containing dosage form |
| US9592197B2 (en) * | 2004-12-16 | 2017-03-14 | Sovereign Pharmaceuticals, Llc | Dosage form containing diphenhydramine and another drug |
| US20060034910A1 (en) * | 2004-08-09 | 2006-02-16 | Sanjay Patel | Pharmaceutical composition for extended release of phenytoin sodium |
| CN101849920A (zh) * | 2004-08-13 | 2010-10-06 | 贝林格尔·英格海姆国际有限公司 | 包含普拉克索或其可药用盐的延长释放小球制剂、其制备方法及其用途 |
| EP2286801A3 (en) | 2004-08-13 | 2012-05-09 | Boehringer Ingelheim International GmbH | Extended release tablet formulation containing pramipexole or a pharmaceutically acceptable salt thereof, method for manufacturing the same and use thereof |
| US20060134175A1 (en) * | 2004-12-22 | 2006-06-22 | Stephen Bartels | Drug eluting pharmaceutical delivery system for treatment of ocular disease and method of use |
| US7529255B2 (en) * | 2005-04-21 | 2009-05-05 | Microsoft Corporation | Peer-to-peer multicasting using multiple transport protocols |
| CN101394849A (zh) | 2006-02-13 | 2009-03-25 | Vanda制药公司 | 咪唑基烷基-吡啶的稳定的剂量制剂 |
| JP5228359B2 (ja) * | 2007-04-12 | 2013-07-03 | ニプロ株式会社 | 主薬粒子及びその製造方法ならびに口腔内崩壊錠 |
| AU2007352872B2 (en) | 2007-05-07 | 2013-03-14 | Evonik Operations Gmbh | Solid dosage forms comprising an enteric coating with accelerated drug release |
| AU2008334933B2 (en) | 2007-12-13 | 2016-01-21 | Vanda Pharmaceuticals Inc. | Method and composition for treating a serotonin receptor-mediated condition |
| CA2709103C (en) | 2007-12-13 | 2017-01-17 | Vanda Pharmaceuticals Inc. | Method and composition for treating an alpha adrenoceptor-mediated condition |
| US20090214665A1 (en) * | 2008-02-26 | 2009-08-27 | Lai Felix S | Controlled Release Muscarinic Receptor Antagonist Formulation |
| US8663671B2 (en) * | 2009-11-05 | 2014-03-04 | Philip Morris Usa Inc. | Methods and compositions for producing hydrogel capsules coated for low permeability and physical integrity |
| US8999393B1 (en) | 2013-01-09 | 2015-04-07 | Edgemont Pharmaceuticals Llc | Sustained release formulations of lorazepam |
| US20230355689A1 (en) | 2019-12-27 | 2023-11-09 | Evelo Biosciences, Inc. | Solid dosage forms containing bacteria and microbial extracellular vesicles |
| TW202140051A (zh) | 2020-01-17 | 2021-11-01 | 美商艾弗洛生物科技股份有限公司 | 具有改善的崩散譜之固體劑型 |
| CN115551486A (zh) | 2020-04-17 | 2022-12-30 | 伊夫罗生物科学公司 | 具有改善的崩解谱的固体剂型 |
| KR20230088724A (ko) | 2020-09-18 | 2023-06-20 | 에벨로 바이오사이언시즈, 인크. | 박테리아의 고체 투여 형태 |
| WO2022094188A1 (en) | 2020-10-29 | 2022-05-05 | Evelo Biosciences, Inc. | Compositions comprising spirulina components |
| TW202237155A (zh) | 2020-12-14 | 2022-10-01 | 美商艾弗洛生物科技股份有限公司 | 細胞外囊泡製劑 |
| EP4267154A1 (en) | 2020-12-22 | 2023-11-01 | Evelo Biosciences, Inc. | Compositions comprising animal hemoglobin |
| WO2022164806A1 (en) | 2021-01-26 | 2022-08-04 | Evelo Biosciences, Inc. | Prevotella extracellular vesicle preparations |
| US20240148797A1 (en) | 2021-02-26 | 2024-05-09 | Evelo Biosciences, Inc. | Compositions and methods for reducing cytokine expression |
| TW202302125A (zh) | 2021-03-05 | 2023-01-16 | 美商艾弗洛生物科技股份有限公司 | 固體劑型 |
| WO2022217030A1 (en) | 2021-04-08 | 2022-10-13 | Evelo Biosciences, Inc. | Pharmaceutical composition containing bacteria |
| WO2022221183A1 (en) | 2021-04-12 | 2022-10-20 | Evelo Biosciences, Inc. | Fournierella extracellular vesicle preparations |
| WO2022251166A2 (en) | 2021-05-25 | 2022-12-01 | Evelo Biosciences, Inc. | Bacterial compositions comprising soy hemoglobin |
| WO2023049268A1 (en) | 2021-09-24 | 2023-03-30 | Evelo Biosciences, Inc. | Solid dosage forms containing bacteria and microbial extracellular vesicles |
| WO2023114295A1 (en) | 2021-12-14 | 2023-06-22 | Evelo Biosciences, Inc. | Veillonella parvula bacteria extracellular vesicle preparations |
| WO2023114296A2 (en) | 2021-12-14 | 2023-06-22 | Evelo Biosciences, Inc. | Extracellular vesicle preparations |
| WO2023114300A1 (en) | 2021-12-14 | 2023-06-22 | Evelo Biosciences, Inc. | Fournierella massiliensis bacteria extracellular vesicle preparations |
| WO2023146843A1 (en) | 2022-01-25 | 2023-08-03 | Evelo Biosciences, Inc. | Extracellular vesicle compositions and methods of use |
| WO2023183396A1 (en) | 2022-03-22 | 2023-09-28 | Evelo Biosciences, Inc. | Compositions and methods of treating inflammation using prevotella histicola |
| WO2023200837A1 (en) | 2022-04-13 | 2023-10-19 | Evelo Biosciences, Inc. | Compositions and methods of treating inflammation using prevotella histicola |
| WO2023239728A1 (en) | 2022-06-07 | 2023-12-14 | Evelo Biosciences, Inc. | Compositions and methods of treating inflammation using prevotella histicola extracellular vesicles |
| WO2024102226A1 (en) | 2022-10-14 | 2024-05-16 | Evelo Biosciences, Inc. | Methods for assaying drug substances and drug products by using cell lines with nf-kb- inducible reporter genes |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4994260A (en) | 1982-05-28 | 1991-02-19 | Astra Lakemedel Aktiebolag | Pharmaceutical mixture |
| US5238686A (en) | 1986-03-27 | 1993-08-24 | Kinaform Technology, Inc. | Sustained-release pharmaceutical preparation |
| US4968508A (en) | 1987-02-27 | 1990-11-06 | Eli Lilly And Company | Sustained release matrix |
| US5540945A (en) * | 1989-05-11 | 1996-07-30 | Chugai Seiyaku Kabushiki Kaisha | Pharmaceutical preparations for oral administration that are adapted to release the drug at appropriate sites in the intestines |
| IL95423A (en) * | 1989-09-21 | 1994-11-11 | American Cyanamid Co | Pulsatile once-a-day delivery systems for minocycline |
| US5368861A (en) * | 1989-10-26 | 1994-11-29 | Nippon Shinyaku Co., Ltd. | Gastric preparation with sustained release |
| US5229131A (en) | 1990-02-05 | 1993-07-20 | University Of Michigan | Pulsatile drug delivery system |
| US5188836A (en) | 1990-07-27 | 1993-02-23 | Warner-Lambert Company | Sustained release formulations |
| US5102668A (en) | 1990-10-05 | 1992-04-07 | Kingaform Technology, Inc. | Sustained release pharmaceutical preparation using diffusion barriers whose permeabilities change in response to changing pH |
| US5286493A (en) | 1992-01-27 | 1994-02-15 | Euroceltique, S.A. | Stabilized controlled release formulations having acrylic polymer coating |
| DE19630035A1 (de) * | 1996-07-25 | 1998-01-29 | Asta Medica Ag | Tramadol Multiple Unit Formulierungen |
| US5885616A (en) * | 1997-08-18 | 1999-03-23 | Impax Pharmaceuticals, Inc. | Sustained release drug delivery system suitable for oral administration |
| US5968554A (en) * | 1998-07-07 | 1999-10-19 | Cascade Development, Inc. A Subsidiary Of Cardinal Health, Inc. | Sustained release pharmaceutical preparation |
-
1999
- 1999-06-23 US US09/338,716 patent/US6312728B1/en not_active Expired - Lifetime
- 1999-06-25 CA CA002337046A patent/CA2337046C/en not_active Expired - Lifetime
- 1999-06-25 WO PCT/US1999/014204 patent/WO2000001369A1/en not_active Ceased
- 1999-06-25 ES ES99935347T patent/ES2226412T3/es not_active Expired - Lifetime
- 1999-06-25 AT AT99935347T patent/ATE274344T1/de not_active IP Right Cessation
- 1999-06-25 JP JP2000557816A patent/JP2003524592A/ja active Pending
- 1999-06-25 AU AU50842/99A patent/AU5084299A/en not_active Abandoned
- 1999-06-25 DE DE69919713T patent/DE69919713T2/de not_active Expired - Lifetime
- 1999-06-25 IL IL14076199A patent/IL140761A0/xx unknown
- 1999-06-25 EP EP99935347A patent/EP1094790B9/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| DE69919713T2 (de) | 2005-09-22 |
| WO2000001369A1 (en) | 2000-01-13 |
| EP1094790B1 (en) | 2004-08-25 |
| JP2003524592A (ja) | 2003-08-19 |
| ES2226412T3 (es) | 2005-03-16 |
| EP1094790A1 (en) | 2001-05-02 |
| IL140761A0 (en) | 2002-02-10 |
| EP1094790A4 (en) | 2003-03-12 |
| AU5084299A (en) | 2000-01-24 |
| US6312728B1 (en) | 2001-11-06 |
| CA2337046C (en) | 2005-08-16 |
| CA2337046A1 (en) | 2000-01-13 |
| DE69919713D1 (de) | 2004-09-30 |
| EP1094790B9 (en) | 2005-05-04 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ATE274344T1 (de) | Pharmazeutische zubereitung mit verzögerter wirkstofffreisetzung von phenytoin natrium | |
| GEP20053501B (en) | Core Tablet for Controlled Release of Gliclazide after Oral Administration | |
| DE69100991D1 (de) | Pharmazeutische formulierungen. | |
| AU4989997A (en) | Soluble form osmotic dose delivery system | |
| DK1406568T3 (da) | Sekventielle lægemiddelafgivelsessystemer | |
| EA200401009A1 (ru) | Предварительно желатинированный крахмал в композиции с контролируемым высвобождением | |
| DE59802670D1 (de) | Osmotisches arzneimittelfreisetzungssystem | |
| DE68909772D1 (de) | Diclofenac-Natrium-Arzneizubereitung mit verlängerter Wirkstoffabgabe. | |
| ATE198152T1 (de) | Oral anzuwendende arzneizubereitung mit verzögerter wirkstoffabgabe | |
| ATE541562T1 (de) | Ibuprofen-suspension | |
| ATE292453T1 (de) | Antivirale arznei | |
| CY1107819T1 (el) | Φαρμακευτικη διαμορφωση της ολανζαπινης | |
| NO20023551D0 (no) | Ibuprofen-inneholdende aktivt middel-preparat | |
| ID28510A (id) | Formulasi oral yang baru untuk agonis atau antagonis 5-ht4 | |
| DE60018629D1 (de) | Carbamazepinformulierung mit verzögerter Freigabe | |
| ES2186207T3 (es) | Metodo para preparacion de formulaciones farmaceuticas. | |
| WO2003061557A3 (en) | Levothyroxine pharmaceutical compositions, methods of making and methods of administration | |
| FR2793685B1 (fr) | Compositions pharmaceutiques, destinees a l'administration par voie orale de phloroglucinol et leur preparation | |
| WO1999047172A3 (en) | Oral pharmaceutical compositions to be taken without liquids, which contain inclusion complexes | |
| GEP20043377B (en) | Pharmaceutical Complex | |
| PT1144420E (pt) | Fosfatidilinositois sulfatados a sua preparacao e a sua utilizacao | |
| ATE258046T1 (de) | Pharmazeutische, metamizol enthaltende brauseformulierung | |
| FR2803521B1 (fr) | Utilisation de l'acide tiludronique et de ses derives chez la volaille pour la preparation d'un medicament destine a prevenir et a traiter l'osteoporose | |
| YU25297A (en) | A controlled release formulation for poorly soluble basic drugs | |
| BR9805026A (pt) | Compostos contdndo tetrahidrolipstatina |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |