ATE270298T1 - Reaktionssystem und verfahren zur verstärkung der lumineszenz von makrocyclischen lanthanid(iii)- komplexen - Google Patents

Reaktionssystem und verfahren zur verstärkung der lumineszenz von makrocyclischen lanthanid(iii)- komplexen

Info

Publication number
ATE270298T1
ATE270298T1 AT00905653T AT00905653T ATE270298T1 AT E270298 T1 ATE270298 T1 AT E270298T1 AT 00905653 T AT00905653 T AT 00905653T AT 00905653 T AT00905653 T AT 00905653T AT E270298 T1 ATE270298 T1 AT E270298T1
Authority
AT
Austria
Prior art keywords
luminescence
enhancing
lanthanide element
energy transfer
lanthanide
Prior art date
Application number
AT00905653T
Other languages
English (en)
Inventor
Robert C Leif
Lidia M Vallarino
Original Assignee
Robert C Leif
Lidia M Vallarino
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Robert C Leif, Lidia M Vallarino filed Critical Robert C Leif
Application granted granted Critical
Publication of ATE270298T1 publication Critical patent/ATE270298T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/18—Bridged systems
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/582—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with fluorescent label
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2474/00—Immunochemical assays or immunoassays characterised by detection mode or means of detection
    • G01N2474/20—Immunohistochemistry assay
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/968—High energy substrates, e.g. fluorescent, chemiluminescent, radioactive

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Food Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Cell Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Biotechnology (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Luminescent Compositions (AREA)
AT00905653T 1999-01-19 2000-01-18 Reaktionssystem und verfahren zur verstärkung der lumineszenz von makrocyclischen lanthanid(iii)- komplexen ATE270298T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US11631699P 1999-01-19 1999-01-19
PCT/US2000/001211 WO2000042048A1 (en) 1999-01-19 2000-01-18 A reagent system and method for increasing the luminescence of lanthanide(iii) macrocyclic complexes

Publications (1)

Publication Number Publication Date
ATE270298T1 true ATE270298T1 (de) 2004-07-15

Family

ID=22366470

Family Applications (1)

Application Number Title Priority Date Filing Date
AT00905653T ATE270298T1 (de) 1999-01-19 2000-01-18 Reaktionssystem und verfahren zur verstärkung der lumineszenz von makrocyclischen lanthanid(iii)- komplexen

Country Status (6)

Country Link
US (2) US6340744B1 (de)
EP (1) EP1150985B1 (de)
AT (1) ATE270298T1 (de)
CA (1) CA2360054A1 (de)
DE (1) DE60011877D1 (de)
WO (1) WO2000042048A1 (de)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000042048A1 (en) * 1999-01-19 2000-07-20 Leif Robert C A reagent system and method for increasing the luminescence of lanthanide(iii) macrocyclic complexes
GB0008618D0 (en) * 2000-04-08 2000-05-31 Univ Strathclyde Analyte detection & apparatus therefor
US20060034954A1 (en) * 2001-02-02 2006-02-16 Bland Jeffrey S Medical composition for balancing bodily processes
AU2002322351A1 (en) * 2001-06-28 2003-03-03 Ia, Inc. Fiber-optic sensor array
WO2005046735A1 (en) * 2003-11-07 2005-05-26 Newport Instruments A reagent system and method for modifying the luminescence of lanthanide(iii) macrocyclic complexes
WO2007026808A1 (ja) * 2005-08-31 2007-03-08 Japan Science And Technology Agency 新規な蛍光標識化合物
KR101449507B1 (ko) * 2005-10-21 2014-10-13 씨드 리써치 앤드 디벨롭먼트, 엘엘씨 아팝토시스의 생체내 검출
GB0613823D0 (en) 2006-07-12 2006-08-23 Univ Durham Assay
KR100993389B1 (ko) * 2006-10-11 2010-11-09 주식회사 엘지화학 나노입자가 표면에 부착된 유기-무기 혼성 재료 및 그제조방법
EP2982963B1 (de) 2006-11-02 2019-08-21 Fluidigm Canada Inc. Partikel mit detektierbarem elementarem code
IL304064A (en) 2009-07-10 2023-08-01 O Scott Linzy Iii Methods and compositions for the treatment of diseases related to the thyroid gland, with a reduced amount of folates
AU2011230619C1 (en) 2010-03-25 2016-06-23 Oregon Health & Science University CMV glycoproteins and recombinant vectors
LT2691530T (lt) 2011-06-10 2018-08-10 Oregon Health & Science University Cmv glikoproteinai ir rekombinantiniai vektoriai
US20130189754A1 (en) 2011-09-12 2013-07-25 International Aids Vaccine Initiative Immunoselection of recombinant vesicular stomatitis virus expressing hiv-1 proteins by broadly neutralizing antibodies
US9402894B2 (en) 2011-10-27 2016-08-02 International Aids Vaccine Initiative Viral particles derived from an enveloped virus
EP2679596B1 (de) 2012-06-27 2017-04-12 International Aids Vaccine Initiative HIV-1 Env-proteinvariante
DE102013205346A1 (de) * 2013-03-26 2014-10-02 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Lanthanoidkomplexbasierte spektroskopische Hämoglobinbestimmung in einem flüssigen biologischen Medium
KR101423589B1 (ko) 2013-03-27 2014-07-28 주식회사 메디센서 란탄족 착물을 포함하는 무독성 형광 입자
US20150065381A1 (en) 2013-09-05 2015-03-05 International Aids Vaccine Initiative Methods of identifying novel hiv-1 immunogens
US10058604B2 (en) 2013-10-07 2018-08-28 International Aids Vaccine Initiative Soluble HIV-1 envelope glycoprotein trimers
FI125976B (en) * 2014-10-27 2016-05-13 Aqsens Oy Method for determination of phosphonates
US10174292B2 (en) 2015-03-20 2019-01-08 International Aids Vaccine Initiative Soluble HIV-1 envelope glycoprotein trimers
EP3072901A1 (de) 2015-03-23 2016-09-28 International Aids Vaccine Initiative Lösliche hiv-1-hüllglykoproteintrimere
BR112018014146A2 (pt) 2016-01-21 2018-12-11 Selux Diagnostics Inc métodos de teste rápido de suscetibilidade antimicrobiana
US9834808B2 (en) 2016-01-21 2017-12-05 SeLux Diagnostics, Inc. Methods for rapid antibiotic susceptibility testing
WO2017211799A1 (en) 2016-06-09 2017-12-14 Radiometer Turku Oy Background blockers for binding assays
CN110603333A (zh) 2016-12-23 2019-12-20 赛录科试诊断公司 用于改进的快速抗微生物剂敏感性测试的方法
WO2018144633A1 (en) * 2017-01-31 2018-08-09 Theranos Ip Company, Llc Methods and devices for improved signal detection from biological samples
CN113607953A (zh) * 2021-08-02 2021-11-05 中国科学院江西稀土研究院 一种稀土配合物荧光微球及其制备方法和应用

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5004565A (en) * 1986-07-17 1991-04-02 The Board Of Governors Of Wayne State University Method and compositions providing enhanced chemiluminescence from 1,2-dioxetanes
CA1340527C (en) 1988-05-31 1999-05-04 Lidia Vallarino Macrocyclic complexes of yttrium, the lanthanides and the actinides having peripheral coupling functionalities
US5696240A (en) * 1991-03-15 1997-12-09 Vallarino; Lidia M. Macrocyclic complexes of yttrium, the lanthanides and the actinides having peripheral coupling functionalities
FI88654C (fi) * 1991-03-15 1993-06-10 Datacity Center Oy Fluorescenshoejningsmetod
DE69131206T2 (de) * 1991-12-05 2000-01-05 Wallac Oy Lumineszierende lanthanidenchelate
WO2000042048A1 (en) * 1999-01-19 2000-07-20 Leif Robert C A reagent system and method for increasing the luminescence of lanthanide(iii) macrocyclic complexes

Also Published As

Publication number Publication date
US6750005B2 (en) 2004-06-15
US6340744B1 (en) 2002-01-22
EP1150985A1 (de) 2001-11-07
EP1150985B1 (de) 2004-06-30
US20020132992A1 (en) 2002-09-19
CA2360054A1 (en) 2000-07-20
WO2000042048A1 (en) 2000-07-20
DE60011877D1 (de) 2004-08-05
EP1150985A4 (de) 2002-03-20

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