ATE270115T1 - Behandlung einer intrazelluläre infektion - Google Patents

Behandlung einer intrazelluläre infektion

Info

Publication number
ATE270115T1
ATE270115T1 AT00919042T AT00919042T ATE270115T1 AT E270115 T1 ATE270115 T1 AT E270115T1 AT 00919042 T AT00919042 T AT 00919042T AT 00919042 T AT00919042 T AT 00919042T AT E270115 T1 ATE270115 T1 AT E270115T1
Authority
AT
Austria
Prior art keywords
agent
target cell
phage
treatment
combating
Prior art date
Application number
AT00919042T
Other languages
English (en)
Inventor
Vladimir Artymovich Pasechnik
Allen Douglas Glen Roberts
Richard James Sharp
Original Assignee
Health Prot Agency
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Health Prot Agency filed Critical Health Prot Agency
Application granted granted Critical
Publication of ATE270115T1 publication Critical patent/ATE270115T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
    • A61K47/6901—Conjugates being cells, cell fragments, viruses, ghosts, red blood cells or viral vectors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
    • A61K47/65—Peptidic linkers, binders or spacers, e.g. peptidic enzyme-labile linkers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Virology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cell Biology (AREA)
  • Hematology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Communicable Diseases (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
AT00919042T 1999-04-09 2000-04-10 Behandlung einer intrazelluläre infektion ATE270115T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9908195.2A GB9908195D0 (en) 1999-04-09 1999-04-09 Treatment of intracellular infection
PCT/GB2000/001350 WO2000061190A2 (en) 1999-04-09 2000-04-10 Treatment of intracellular infection

Publications (1)

Publication Number Publication Date
ATE270115T1 true ATE270115T1 (de) 2004-07-15

Family

ID=10851274

Family Applications (1)

Application Number Title Priority Date Filing Date
AT00919042T ATE270115T1 (de) 1999-04-09 2000-04-10 Behandlung einer intrazelluläre infektion

Country Status (12)

Country Link
US (1) US6660264B1 (de)
EP (1) EP1169063B1 (de)
JP (1) JP2002541217A (de)
AT (1) ATE270115T1 (de)
AU (1) AU772115B2 (de)
CA (1) CA2372078A1 (de)
DE (1) DE60011880T2 (de)
DK (1) DK1169063T3 (de)
ES (1) ES2220451T3 (de)
GB (1) GB9908195D0 (de)
PT (1) PT1169063E (de)
WO (1) WO2000061190A2 (de)

Families Citing this family (17)

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WO2002034892A1 (en) * 2000-10-25 2002-05-02 Intercell Biomedizinische Forschungs- Und Entwicklungs Ag Modified phage, comprising a non-lytic modification and expressing a kil-gene
WO2002092116A1 (en) * 2001-05-15 2002-11-21 Faulk Pharmaceuticals, Inc. Targeted delivery of drugs for the treatment of viral infections
GB0115385D0 (en) * 2001-06-22 2001-08-15 Regma Biotechnologies Ltd Novel preparation
GB0118009D0 (en) * 2001-07-24 2001-09-19 Regma Biotechnologies Ltd Novel preparation
CA2869088A1 (en) * 2002-02-07 2003-08-14 Massachusetts Institute Of Technology Anti-pathogen treatments
GB0205786D0 (en) * 2002-03-12 2002-04-24 Regma Bio Technologies Ltd Novel Composition
GB0209680D0 (en) * 2002-04-27 2002-06-05 Univ Strathclyde Immobilisation and stabilisation of bacteriophage
DE10235967B4 (de) * 2002-08-06 2005-09-08 Bayer Healthcare Ag Methode zum Identifizieren von Substanzen mit antimikrobieller Wirkung
WO2004087924A2 (en) * 2003-03-31 2004-10-14 MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. Method for delivery of substances to intracellular microorganisms
US8703134B2 (en) 2003-05-15 2014-04-22 Iogenetics, Llc Targeted cryptosporidium biocides
US8394379B2 (en) 2003-05-15 2013-03-12 Iogenetics, Llc Targeted cryptosporidium biocides
WO2005080410A1 (en) * 2004-02-20 2005-09-01 Genesis Research And Development Corporation Limited Targeted delivery of rna interference molecules for the treatment of ige-mediated disorders
US8080560B2 (en) * 2004-12-17 2011-12-20 3M Innovative Properties Company Immune response modifier formulations containing oleic acid and methods
DK2102338T3 (da) * 2006-12-12 2010-11-01 Morphosys Ag Internalisering
US8619257B2 (en) 2007-12-13 2013-12-31 Kimberley-Clark Worldwide, Inc. Recombinant bacteriophage for detection of nosocomial infection
PT2646470T (pt) 2010-11-30 2017-05-03 Hoffmann La Roche Anticorpos anti-recetor da transferrina de baixa afinidade e a sua utilização na transferência de scfv terapêuticos através da barreira hematoencefálica
EP4114422A4 (de) * 2020-03-06 2024-09-18 Endolytix Tech Inc Zusammensetzungen und verfahren zur behandlung intrazellulärer bakterieller infektionen

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GB829266A (en) 1957-03-20 1960-03-02 Biogena A method of manufacturing bacteriophages in solid dry form
AU4308689A (en) 1988-09-02 1990-04-02 Protein Engineering Corporation Generation and selection of recombinant varied binding proteins
WO1992015605A2 (en) 1991-03-01 1992-09-17 Protein Engineering Corporation Inhibitors of human neutrophil elastase and human cathepsin g
US5108921A (en) 1989-04-03 1992-04-28 Purdue Research Foundation Method for enhanced transmembrane transport of exogenous molecules
IL93982A0 (en) 1989-04-03 1991-01-31 Purdue Research Foundation Method for enhancing transmembrane transport of exogenous molecules
DE59106279D1 (de) 1990-05-18 1995-09-21 Genentech Inc Neue protein-polykation-konjugate.
AU665190B2 (en) 1990-07-10 1995-12-21 Cambridge Antibody Technology Limited Methods for producing members of specific binding pairs
GB9015198D0 (en) 1990-07-10 1990-08-29 Brien Caroline J O Binding substance
AU8740491A (en) 1990-09-28 1992-04-28 Protein Engineering Corporation Proteinaceous anti-dental plaque agents
AU660629B2 (en) 1990-10-01 1995-07-06 University Of Connecticut, The Targeting viruses and cells for selective internalization by cells
ATE363532T1 (de) 1991-03-01 2007-06-15 Dyax Corp Verfahren zur herstellung bindender miniproteine
DE4110409C2 (de) 1991-03-29 1999-05-27 Boehringer Ingelheim Int Neue Protein-Polykation-Konjugate
DE4115038A1 (de) 1991-05-08 1992-11-12 Genentech Inc Neue konjugate, bestehend aus einem glykoprotein und einer nukleinsaeure-bindenden substanz
WO1993000103A1 (en) 1991-06-21 1993-01-07 The Wistar Institute Of Anatomy And Biology Chimeric envelope proteins for viral targeting
NZ244306A (en) 1991-09-30 1995-07-26 Boehringer Ingelheim Int Composition for introducing nucleic acid complexes into eucaryotic cells, complex containing nucleic acid and endosomolytic agent, peptide with endosomolytic domain and nucleic acid binding domain and preparation
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DE4311651A1 (de) 1993-04-08 1994-10-13 Boehringer Ingelheim Int Virus für den Transport von Fremd-DNA in höhere eukaryotische Zellen
EP0691828A4 (de) 1993-04-27 1996-07-17 Symbiotech Inc Verfahren zum nachweisen von verbindungen unter verwendungvon chemisch veränderten lambdoiden bakteriophagen
DE4335025A1 (de) 1993-10-14 1995-04-20 Boehringer Ingelheim Int Endosomolytisch wirksame Partikel
JPH09511397A (ja) 1994-04-05 1997-11-18 エクスポネンシャル バイオセラピーズ，インコーポレイテッド 遺伝子型改変バクテリオファージによる抗菌治療
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AU3737297A (en) 1996-08-05 1998-02-25 Brigham And Women's Hospital Bacteriophage-mediated gene therapy
US6054312A (en) 1997-08-29 2000-04-25 Selective Genetics, Inc. Receptor-mediated gene delivery using bacteriophage vectors
CA2302292A1 (en) * 1997-08-29 1999-03-04 Selective Genetics, Inc. Methods using phage display for selecting internalizing ligands for gene delivery
DE19909770A1 (de) 1999-03-05 2000-09-07 Werner Lubitz Bakterienghosts als Träger- und Targetingvehikel

Also Published As

Publication number Publication date
EP1169063B1 (de) 2004-06-30
WO2000061190A3 (en) 2001-03-01
GB9908195D0 (en) 1999-06-02
AU3979800A (en) 2000-11-14
AU772115B2 (en) 2004-04-08
US6660264B1 (en) 2003-12-09
CA2372078A1 (en) 2000-10-19
PT1169063E (pt) 2004-10-29
EP1169063A2 (de) 2002-01-09
WO2000061190A2 (en) 2000-10-19
DE60011880D1 (de) 2004-08-05
DE60011880T2 (de) 2005-08-25
ES2220451T3 (es) 2004-12-16
JP2002541217A (ja) 2002-12-03
DK1169063T3 (da) 2004-11-01

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