ATE264864T1 - Verbesserte chimäre oligonukleotidvektoren - Google Patents

Verbesserte chimäre oligonukleotidvektoren

Info

Publication number
ATE264864T1
ATE264864T1 AT98908601T AT98908601T ATE264864T1 AT E264864 T1 ATE264864 T1 AT E264864T1 AT 98908601 T AT98908601 T AT 98908601T AT 98908601 T AT98908601 T AT 98908601T AT E264864 T1 ATE264864 T1 AT E264864T1
Authority
AT
Austria
Prior art keywords
analogs
oligonucleotides
portions
end modifications
target complementary
Prior art date
Application number
AT98908601T
Other languages
English (en)
Inventor
Alex Andrus
Robert G Kuimelis
Original Assignee
Applera Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Applera Corp filed Critical Applera Corp
Application granted granted Critical
Publication of ATE264864T1 publication Critical patent/ATE264864T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • C07H21/04—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids with deoxyribosyl as saccharide radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H1/00—Processes for the preparation of sugar derivatives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • C07H21/02—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids with ribosyl as saccharide radical

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biochemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
AT98908601T 1997-03-03 1998-02-19 Verbesserte chimäre oligonukleotidvektoren ATE264864T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US3924497P 1997-03-03 1997-03-03
PCT/US1998/003224 WO1998039353A1 (en) 1997-03-03 1998-02-19 Improved chimeric oligonucleotide vectors

Publications (1)

Publication Number Publication Date
ATE264864T1 true ATE264864T1 (de) 2004-05-15

Family

ID=21904439

Family Applications (1)

Application Number Title Priority Date Filing Date
AT98908601T ATE264864T1 (de) 1997-03-03 1998-02-19 Verbesserte chimäre oligonukleotidvektoren

Country Status (5)

Country Link
EP (1) EP0931090B1 (de)
AT (1) ATE264864T1 (de)
AU (1) AU6659898A (de)
DE (1) DE69823324T2 (de)
WO (1) WO1998039353A1 (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6054568A (en) * 1998-01-16 2000-04-25 The Perkin-Elmer Corporation Nucleobase oligomers
AU6071300A (en) * 1999-07-06 2001-01-22 Isis Pharmaceuticals, Inc. Oligonucleotides incorporating both 2-aminoadenine and 5-substituted pyrimidines
US11555188B2 (en) * 2017-07-26 2023-01-17 Nissan Chemical Corporation Single-stranded oligonucleotide

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0733059B1 (de) * 1993-12-09 2000-09-13 Thomas Jefferson University Verbindungen und verfahren zur ortsspezifischen mutation in eukaryotischen zellen

Also Published As

Publication number Publication date
DE69823324T2 (de) 2005-02-24
EP0931090A1 (de) 1999-07-28
DE69823324D1 (de) 2004-05-27
WO1998039353A1 (en) 1998-09-11
EP0931090B1 (de) 2004-04-21
AU6659898A (en) 1998-09-22

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