ATE264499T1 - Fluoreszenzintensitätsanalyse unter verwendung einer vielzahl von verteilungen: konkurrierende bestimmung von diffusionszeiten und molekularer helligkeit - Google Patents
Fluoreszenzintensitätsanalyse unter verwendung einer vielzahl von verteilungen: konkurrierende bestimmung von diffusionszeiten und molekularer helligkeitInfo
- Publication number
- ATE264499T1 ATE264499T1 AT01903729T AT01903729T ATE264499T1 AT E264499 T1 ATE264499 T1 AT E264499T1 AT 01903729 T AT01903729 T AT 01903729T AT 01903729 T AT01903729 T AT 01903729T AT E264499 T1 ATE264499 T1 AT E264499T1
- Authority
- AT
- Austria
- Prior art keywords
- particles
- distributions
- variety
- fluorescence intensity
- intensity analysis
- Prior art date
Links
- 238000009792 diffusion process Methods 0.000 title abstract 2
- 230000002860 competitive effect Effects 0.000 title 1
- 239000002245 particle Substances 0.000 abstract 5
- 238000005259 measurement Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 238000012544 monitoring process Methods 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/645—Specially adapted constructive features of fluorimeters
- G01N21/6456—Spatial resolved fluorescence measurements; Imaging
- G01N21/6458—Fluorescence microscopy
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01J—MEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
- G01J3/00—Spectrometry; Spectrophotometry; Monochromators; Measuring colours
- G01J3/28—Investigating the spectrum
- G01J3/44—Raman spectrometry; Scattering spectrometry ; Fluorescence spectrometry
- G01J3/4406—Fluorescence spectrometry
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01J—MEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
- G01J3/00—Spectrometry; Spectrophotometry; Monochromators; Measuring colours
- G01J3/28—Investigating the spectrum
- G01J3/457—Correlation spectrometry, e.g. of the intensity
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01J—MEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
- G01J3/00—Spectrometry; Spectrophotometry; Monochromators; Measuring colours
- G01J3/28—Investigating the spectrum
- G01J2003/2866—Markers; Calibrating of scan
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N2021/6417—Spectrofluorimetric devices
- G01N2021/6421—Measuring at two or more wavelengths
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/645—Specially adapted constructive features of fluorimeters
- G01N2021/6463—Optics
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/6408—Fluorescence; Phosphorescence with measurement of decay time, time resolved fluorescence
Landscapes
- Physics & Mathematics (AREA)
- Spectroscopy & Molecular Physics (AREA)
- Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Biochemistry (AREA)
- Analytical Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US18156400P | 2000-02-10 | 2000-02-10 | |
EP00126774 | 2000-12-06 | ||
PCT/EP2001/001431 WO2001059416A1 (en) | 2000-02-10 | 2001-02-09 | Fluorescence intensity multiple distributions analysis: concurrent determination of diffusion times and molecular brightness |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE264499T1 true ATE264499T1 (de) | 2004-04-15 |
Family
ID=26071648
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT01903729T ATE264499T1 (de) | 2000-02-10 | 2001-02-09 | Fluoreszenzintensitätsanalyse unter verwendung einer vielzahl von verteilungen: konkurrierende bestimmung von diffusionszeiten und molekularer helligkeit |
Country Status (5)
Country | Link |
---|---|
EP (1) | EP1254353B1 (de) |
AT (1) | ATE264499T1 (de) |
AU (1) | AU3172301A (de) |
DE (1) | DE60102797T2 (de) |
WO (1) | WO2001059416A1 (de) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2007508810A (ja) | 2003-09-30 | 2007-04-12 | エヴォテック ニューロサイエンシス ゲゼルシャフト ミット ベシュレンクテル ハフツング | スルホトランスフェラーゼの神経変性疾患に関する診断的および治療的使用 |
EP1528379A1 (de) * | 2003-10-27 | 2005-05-04 | Evotec Technologies GmbH | Verfahren zum Auflösen von Spezies von fluoreszierenden Molekülen in einer Probe |
US20080301821A1 (en) | 2004-08-11 | 2008-12-04 | Evotec Neurosciences Gmbh | Diagnostic and Therapeutic use of a Plasma Membrane Atpase |
US20090172827A1 (en) | 2005-05-27 | 2009-07-02 | Johannes Pohlner | Kcnn3 as diagnostic and therapeutic target for neurodegenerative diseases |
JP4929277B2 (ja) | 2005-05-30 | 2012-05-09 | 武田薬品工業株式会社 | 神経変性疾患に対する診断上及び治療上の標的prkxタンパク質 |
US20090133135A1 (en) | 2005-06-01 | 2009-05-21 | Evotec Neurosciences Gmbh | Diagnostic and Therapeutic Target SLC39A11 Proteins for Neurodegenerative Diseases |
ATE495269T1 (de) | 2005-06-16 | 2011-01-15 | Evotec Neurosciences Gmbh | Adarb2 proteine als diagnostische und therapeutische targets für neurodegenerative erkrankungen |
EP2053397A1 (de) | 2007-10-25 | 2009-04-29 | EVOTEC Neurosciences GmbH | PPM1E-Proteine und Nukleinsäuren als Targets für neurodegenerative Erkrankungen |
DE102013213362A1 (de) | 2013-07-08 | 2015-01-08 | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. | Verfahren zur Identifizierung und Quantifizierung von emittierenden Teilchen in Systemen |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1595422A (en) * | 1977-04-28 | 1981-08-12 | Nat Res Dev | Scaning microscopes |
EP0884583A1 (de) * | 1997-06-10 | 1998-12-16 | Evotec BioSystems GmbH | Verfahren zur Charakterisierung von Proben in einem mindestens zweidimensionalen Raum spezifischer physikalischer Eigenschaften |
EP1063502A1 (de) * | 1999-06-23 | 2000-12-27 | Evotec BioSystems AG | Verfahren zur Charakterisierung fluoreszierender Moleküle oder anderer Teilchen unter Verwendung von erzeugenden Funktionen |
-
2001
- 2001-02-09 WO PCT/EP2001/001431 patent/WO2001059416A1/en active IP Right Grant
- 2001-02-09 AT AT01903729T patent/ATE264499T1/de not_active IP Right Cessation
- 2001-02-09 AU AU31723/01A patent/AU3172301A/en not_active Abandoned
- 2001-02-09 DE DE60102797T patent/DE60102797T2/de not_active Expired - Lifetime
- 2001-02-09 EP EP01903729A patent/EP1254353B1/de not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
WO2001059416A1 (en) | 2001-08-16 |
EP1254353A1 (de) | 2002-11-06 |
DE60102797T2 (de) | 2005-09-08 |
EP1254353B1 (de) | 2004-04-14 |
AU3172301A (en) | 2001-08-20 |
DE60102797D1 (de) | 2004-05-19 |
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RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |